HK1159989A1 - Bicyclic triazole derivatives for treating tumors - Google Patents

Bicyclic triazole derivatives for treating tumors

Info

Publication number
HK1159989A1
HK1159989A1 HK12100381.3A HK12100381A HK1159989A1 HK 1159989 A1 HK1159989 A1 HK 1159989A1 HK 12100381 A HK12100381 A HK 12100381A HK 1159989 A1 HK1159989 A1 HK 1159989A1
Authority
HK
Hong Kong
Prior art keywords
triazole derivatives
treating tumors
bicyclic triazole
bicyclic
tumors
Prior art date
Application number
HK12100381.3A
Other languages
English (en)
Inventor
Frank Stieber
Oliver Schadt
Dieter Dorsch
Andree Blaukat
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HK1159989A1 publication Critical patent/HK1159989A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK12100381.3A 2008-08-14 2012-01-12 Bicyclic triazole derivatives for treating tumors HK1159989A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008037790A DE102008037790A1 (de) 2008-08-14 2008-08-14 Bicyclische Triazolderivate
PCT/EP2009/005172 WO2010017870A1 (de) 2008-08-14 2009-07-16 Bicyclische triazolderivate zur behandlung von tumoren

Publications (1)

Publication Number Publication Date
HK1159989A1 true HK1159989A1 (en) 2012-08-10

Family

ID=41138729

Family Applications (1)

Application Number Title Priority Date Filing Date
HK12100381.3A HK1159989A1 (en) 2008-08-14 2012-01-12 Bicyclic triazole derivatives for treating tumors

Country Status (17)

Country Link
US (1) US8435986B2 (ja)
EP (1) EP2310013B1 (ja)
JP (1) JP5475778B2 (ja)
KR (1) KR20110051243A (ja)
CN (1) CN102123710B (ja)
AR (1) AR073055A1 (ja)
AU (1) AU2009281491B2 (ja)
BR (1) BRPI0914555A2 (ja)
CA (1) CA2733941C (ja)
DE (1) DE102008037790A1 (ja)
EA (1) EA201100334A1 (ja)
ES (1) ES2648233T3 (ja)
HK (1) HK1159989A1 (ja)
IL (1) IL211193A0 (ja)
MX (1) MX2011001511A (ja)
WO (1) WO2010017870A1 (ja)
ZA (1) ZA201101899B (ja)

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TWI796596B (zh) 2018-02-13 2023-03-21 美商基利科學股份有限公司 Pd‐1/pd‐l1抑制劑
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KR20230159715A (ko) 2018-07-13 2023-11-21 길리애드 사이언시즈, 인코포레이티드 Pd-1/pd-l1 억제제
KR102635333B1 (ko) 2018-10-24 2024-02-15 길리애드 사이언시즈, 인코포레이티드 Pd-1/pd-l1 억제제

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Also Published As

Publication number Publication date
AU2009281491A1 (en) 2010-02-18
BRPI0914555A2 (pt) 2015-12-15
ZA201101899B (en) 2011-11-30
DE102008037790A1 (de) 2010-02-18
EP2310013B1 (de) 2017-08-23
MX2011001511A (es) 2011-03-15
EA201100334A1 (ru) 2011-08-30
KR20110051243A (ko) 2011-05-17
CN102123710B (zh) 2012-11-07
CN102123710A (zh) 2011-07-13
JP5475778B2 (ja) 2014-04-16
EP2310013A1 (de) 2011-04-20
US8435986B2 (en) 2013-05-07
IL211193A0 (en) 2011-04-28
ES2648233T3 (es) 2017-12-29
US20110135600A1 (en) 2011-06-09
WO2010017870A1 (de) 2010-02-18
AU2009281491B2 (en) 2014-02-20
CA2733941C (en) 2016-10-04
JP2011530545A (ja) 2011-12-22
AR073055A1 (es) 2010-10-13
CA2733941A1 (en) 2010-02-18

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20170716