HK1159494A1 - 使用粘膜緩釋生物粘附治療載體治療粘膜中的炎症和炎性疼痛 - Google Patents

使用粘膜緩釋生物粘附治療載體治療粘膜中的炎症和炎性疼痛

Info

Publication number
HK1159494A1
HK1159494A1 HK11114048.0A HK11114048A HK1159494A1 HK 1159494 A1 HK1159494 A1 HK 1159494A1 HK 11114048 A HK11114048 A HK 11114048A HK 1159494 A1 HK1159494 A1 HK 1159494A1
Authority
HK
Hong Kong
Prior art keywords
mucosal
mucosa
inflammatory pain
prolonged release
treating inflammation
Prior art date
Application number
HK11114048.0A
Other languages
English (en)
Inventor
Pierre Attali
Caroline Lemarchand
Vanessa Roulet
Claire Scheuir
Lorraine Zakin
Original Assignee
Onxeo S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Onxeo S A filed Critical Onxeo S A
Publication of HK1159494A1 publication Critical patent/HK1159494A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41681,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2063Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK11114048.0A 2008-09-18 2011-12-29 使用粘膜緩釋生物粘附治療載體治療粘膜中的炎症和炎性疼痛 HK1159494A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9805308P 2008-09-18 2008-09-18
EP08164648A EP2165706A1 (en) 2008-09-18 2008-09-18 Treating Inflammatory Pain in Mucosa of the Oral Cavity Using Mucosal Prolonged Release Bioadhesive Therapeutic Carriers.
PCT/EP2009/062068 WO2010031819A1 (en) 2008-09-18 2009-09-17 Treating inflammation and inflammatory pain in mucosa using mucosal prolonged release bioadhesive therapeutic carriers.

Publications (1)

Publication Number Publication Date
HK1159494A1 true HK1159494A1 (zh) 2012-08-03

Family

ID=40010612

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11114048.0A HK1159494A1 (zh) 2008-09-18 2011-12-29 使用粘膜緩釋生物粘附治療載體治療粘膜中的炎症和炎性疼痛

Country Status (15)

Country Link
US (3) US20110288140A1 (zh)
EP (2) EP2165706A1 (zh)
JP (2) JP5693455B2 (zh)
KR (1) KR101352210B1 (zh)
CN (1) CN102170877B (zh)
AU (1) AU2009294612B2 (zh)
CA (1) CA2732893C (zh)
DK (1) DK2395997T3 (zh)
ES (1) ES2569611T3 (zh)
HK (1) HK1159494A1 (zh)
HU (1) HUE027226T2 (zh)
IL (1) IL210916A (zh)
PL (1) PL2395997T3 (zh)
WO (1) WO2010031819A1 (zh)
ZA (1) ZA201101175B (zh)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2165706A1 (en) 2008-09-18 2010-03-24 BioAlliance Pharma Treating Inflammatory Pain in Mucosa of the Oral Cavity Using Mucosal Prolonged Release Bioadhesive Therapeutic Carriers.
JP5498571B2 (ja) 2009-04-30 2014-05-21 ミッドウェスタン ユニバーシティ センタキンを用いた新規の治療方法
US20130096170A1 (en) 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
WO2013076160A1 (en) 2011-11-21 2013-05-30 Université Libre de Bruxelles Sustained release formulations useful in the treatment of diseases
US8242158B1 (en) 2012-01-04 2012-08-14 Hospira, Inc. Dexmedetomidine premix formulation
US9108942B1 (en) 2014-11-05 2015-08-18 Mahesh Kandula Compositions and methods for the treatment of moderate to severe pain
US20150250782A1 (en) * 2012-08-31 2015-09-10 Pharmazz, Inc. Methods and Compositions for Hypotensive Resuscitation
KR101446066B1 (ko) * 2012-12-14 2014-10-01 박재돈 구안파신 함유 경구용 서방성 캡슐제 조성물
US9333187B1 (en) 2013-05-15 2016-05-10 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory bowel disease
CA2914461A1 (en) 2013-06-04 2014-12-11 Cellixbio Private Limited Compositions and methods for the treatment of diabetes and pre-diabetes
KR101831290B1 (ko) 2013-10-07 2018-02-22 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 조성물을 사용하여 주의력 결핍 과잉행동 장애, 불안 및 불면증을 치료하기 위한 방법 및 조성물
ES2847936T3 (es) 2013-10-07 2021-08-04 Teikoku Pharma Usa Inc Métodos y composiciones para el suministro transdérmico de una cantidad no sedante de dexmedetomidina
KR101827980B1 (ko) 2013-10-07 2018-02-13 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 전달 장치 및 이의 사용 방법
US9096537B1 (en) 2014-12-31 2015-08-04 Mahesh Kandula Compositions and methods for the treatment of mucositis
RU2552307C1 (ru) * 2014-06-17 2015-06-10 Ольга Александровна Гализина Способ лечения воспалительных заболеваний пародонта и слизистой оболочки полости рта
CN104138362A (zh) * 2014-08-07 2014-11-12 力品药业(厦门)有限公司 一种盐酸可乐定缓释片的制备方法
WO2016046835A1 (en) 2014-09-26 2016-03-31 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy and neurological disorders
CA2967908C (en) 2014-09-29 2020-11-17 Mahesh Kandula Compositions and methods for the treatment of multiple sclerosis
US9932294B2 (en) 2014-12-01 2018-04-03 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
WO2016105449A1 (en) * 2014-12-22 2016-06-30 Seth Lederman Compounds for use as pain therapeutics
SG11201705524SA (en) 2015-01-06 2017-08-30 Cellix Bio Private Ltd Compositions and methods for the treatment of inflammation and pain
KR102375047B1 (ko) * 2015-04-17 2022-03-15 모노파르 테라퓨틱스 인크. 화학요법의 유해 부작용 예방 및/또는 치료에 사용하기 위한 클로니딘 및/또는 클로니딘 유도체
EP3294292A1 (en) * 2015-05-13 2018-03-21 Monopar Therapeutics Inc. Clonidine and/or clonidine derivatives for use in the prevention of skin injury resulting from radiotherapy
KR102544141B1 (ko) * 2016-09-29 2023-06-16 에스케이케미칼 주식회사 라코사미드 서방성 제제
CN107412200B (zh) * 2017-04-27 2018-07-24 哈尔滨乾佰纳生物药业有限公司 一种具有生物粘附性的缓释型口腔溃疡膜及其制备方法
US20220031664A1 (en) * 2020-07-28 2022-02-03 Melt Pharmaceuticals, Inc. Pharmaceutical compositions comprising antiemetics and alpha-2-adrenergic receptor agonists and methods of using the same for anesthesiological applications

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3133862A (en) 1960-07-22 1964-05-19 Miles Lab Buccal tablet containing vitamin a and sodium proteinate
US4201211A (en) 1977-07-12 1980-05-06 Alza Corporation Therapeutic system for administering clonidine transdermally
US4291015A (en) 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4590067A (en) * 1984-10-18 1986-05-20 Peritain, Ltd. Treatment for periodontal disease
US4765974A (en) 1985-12-24 1988-08-23 Nitto Electric Industrial Co., Ltd. Preparation for percutaneous administration
US5175052A (en) 1988-05-11 1992-12-29 Nitto Denko Corporation Adhesive tape preparation of clonidine
US5102870A (en) * 1989-04-14 1992-04-07 Schering Ag Treatment and prevention of oral mucositis with growth factors
FR2665357B1 (fr) 1990-07-31 1995-03-31 Aiache Jean Marc Procede de preparation d'une forme galenique bio-adhesive et forme galenique ainsi preparee.
US5578315A (en) 1993-12-01 1996-11-26 Rutgers, The State University Of New Jersey Mucosal adhesive device for long-acting delivery of pharmaceutical combinations in oral cavity
SE518578C2 (sv) 1994-06-15 2002-10-29 Gs Dev Ab Lipidbaserad komposition
US5766620A (en) 1995-10-23 1998-06-16 Theratech, Inc. Buccal delivery of glucagon-like insulinotropic peptides
US6210699B1 (en) 1999-04-01 2001-04-03 Watson Pharmaceuticals, Inc. Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity
GB0010446D0 (en) 2000-04-28 2000-06-14 Glaxo Wellcome Kk Pharmaceutical formulation
FR2827517B1 (fr) * 2001-07-23 2003-10-24 Bioalliance Pharma Systemes therapeutiques bioadhesifs a liberation prolongee
US7345065B2 (en) 2002-05-21 2008-03-18 Allergan, Inc. Methods and compositions for alleviating pain
US20050059744A1 (en) * 2003-09-12 2005-03-17 Allergan, Inc. Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions
WO2005055945A2 (en) * 2003-12-08 2005-06-23 Gel-Del Technologies, Inc. Mucoadhesive drug delivery devices and methods of making and using thereof
US20060253100A1 (en) * 2004-10-22 2006-11-09 Medtronic, Inc. Systems and Methods to Treat Pain Locally
EP1848403B8 (en) * 2005-01-14 2010-05-19 Camurus Ab Topical bioadhesive formulations
HUE054887T2 (hu) * 2005-06-17 2021-10-28 Wisconsin Alumni Res Found Topikális érösszehúzó készítmények és eljárások sejtek védelmére rák kemoterápia és radioterápia alatt
FR2889417B1 (fr) 2005-08-05 2008-02-08 Roquette Freres Proteines de pois texturee
WO2007096906A2 (en) * 2006-02-27 2007-08-30 Panacea Biotec Ltd. Novel buccoadhesive compositions and process of preparation thereof
EP1837020A1 (en) * 2006-03-24 2007-09-26 Bioalliance Pharma Mucosal bioadhesive slow release carrier for delivering active principles
EP1972332A1 (en) 2007-03-23 2008-09-24 BioAlliance Pharma Mucosal bioadhesive slow release carrier for delivering active principles
WO2009049648A2 (en) 2007-10-17 2009-04-23 Pharmathen S.A. Improved pharmaceutical composition containing antiviral agent and method for the preparation thereof
US20090137477A1 (en) 2007-11-09 2009-05-28 Bioalliance Pharma Treatment of oropharyngeal candidiasis in cancer patients
EP2165706A1 (en) 2008-09-18 2010-03-24 BioAlliance Pharma Treating Inflammatory Pain in Mucosa of the Oral Cavity Using Mucosal Prolonged Release Bioadhesive Therapeutic Carriers.
US8592434B2 (en) 2009-12-09 2013-11-26 Bioalliance Pharma Sa Mucoadhesive buccal tablets for the treatment of orofacial herpes
WO2011070125A1 (en) 2009-12-09 2011-06-16 Bioalliance Pharma Mucoadhesive buccal tablets for the treatment of orofacial herpes

Also Published As

Publication number Publication date
WO2010031819A1 (en) 2010-03-25
IL210916A0 (en) 2011-04-28
US20130274306A1 (en) 2013-10-17
EP2395997A1 (en) 2011-12-21
JP2015013889A (ja) 2015-01-22
JP5693455B2 (ja) 2015-04-01
US9089559B2 (en) 2015-07-28
HUE027226T2 (en) 2016-10-28
US20150148398A1 (en) 2015-05-28
AU2009294612B2 (en) 2015-08-20
AU2009294612A1 (en) 2010-03-25
CA2732893A1 (en) 2010-03-25
KR101352210B1 (ko) 2014-02-17
CN102170877A (zh) 2011-08-31
IL210916A (en) 2016-09-29
KR20110063471A (ko) 2011-06-10
EP2165706A1 (en) 2010-03-24
ES2569611T3 (es) 2016-05-11
US9192599B2 (en) 2015-11-24
ZA201101175B (en) 2011-10-26
PL2395997T3 (pl) 2016-07-29
JP2012502952A (ja) 2012-02-02
CN102170877B (zh) 2014-08-27
EP2395997B1 (en) 2016-02-10
DK2395997T3 (en) 2016-05-02
US20110288140A1 (en) 2011-11-24
CA2732893C (en) 2017-03-14

Similar Documents

Publication Publication Date Title
HK1159494A1 (zh) 使用粘膜緩釋生物粘附治療載體治療粘膜中的炎症和炎性疼痛
HRP20190059T1 (hr) Pripravci za liječenje boli i/ili upale
EP2120823A4 (en) DRESSING FORMULATIONS FOR PREVENTING AND REDUCING SCAR TRAINING
HK1148232A1 (zh) 粘膜組織敷料及其使用方法
EP2358378A4 (en) TOPICAL FORMULATION FOR THE TREATMENT OF INFLAMMATORY DISEASE, SKIN AND SLAUGHTER DISEASES AND SIMILAR DISEASES
EP2273982A4 (en) DELAYED FORMS HAVING DIFFERENT RELEASING PROFILES TO MITIGATE, PREVENT OR TREAT PAIN OR INFLAMMATION
EP2293751A4 (en) APPARATUS FOR MULTI-DIRECTIVE SPONGE ADMINISTRATION AND METHOD FOR THE APPLICATION THEREFOR
EP2190408A4 (en) ANALGETIC AND ANTI-INFLAMMATORY COMPOSITIONS AND METHOD FOR THE TREATMENT, PREVENTION OR TREATMENT OF PAIN AND IGNITION
HK1153684A1 (zh) 在皮膚傷口癒合中使用幹細胞的組合物和方法
AP2657A (en) Anti-inflammatory compositions comprising tetracyclines and use thereof in therapy
EP2219448A4 (en) THERAPEUTIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASES AND SUFFERINGS
IL192130A0 (en) METHODS OF TRETING PAIN AND INFLAMMATION IN NEURONAL TISSUE USING IL-31Ra AND OSMRb ANTAGONISTS
EP2215264A4 (en) PREVENTION AND TREATMENT OF INFLAMMATION AND ORGAN DAMAGE AFTER ISCHEMIA / REPERFUSION USING MFG-E8
EP2408740A4 (en) COMPOUNDS FOR THE TREATMENT OF INFLAMMATION AND PAIN
WO2009155116A9 (en) Methods of reducing pain and inflammation
ZA201008810B (en) Pharmaceutical transdermal compositions and method for treating inflammation in cattle
IL207965A0 (en) N-substitutedbenzenepropanamide ofr denzenepropenamide derivatives for use in the treatment of pain and inflammation
HU0700051D0 (en) Treatment of gastrointestinal disorders associated with enhanced motility and inflammation using kynurenic acid
HK1143756A1 (en) Use of sulfonyl-substituted 2-sulfonylaminobenzoic acid n-phenylamides in the treatment of pain
IL197237A0 (en) Use of c7 sugars in prevention and treatment of mycoses
PL2475361T3 (pl) N-podstawione benzenopropanoamidy do stosowania w leczeniu bólu i stanu zapalnego
HK1165280A1 (zh) 芐達明在治療 依賴性疾病中的用途
EP2429559A4 (en) TREATMENT OF PAIN AND / OR INFLAMMATION AS WELL AS TREATMENT AND PREVENTION OF SKIN OR SLICING DISEASES OR TROUBLES
TWI340035B (en) Lemnalol applying for treating inflammation and pain
HK1144247A1 (en) Use of osteoblasts in the treatment of inflammatory rheumatic diseases

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230915