HK1157784A1 - Quinoxalinedione derivatives - Google Patents
Quinoxalinedione derivativesInfo
- Publication number
- HK1157784A1 HK1157784A1 HK11112373.9A HK11112373A HK1157784A1 HK 1157784 A1 HK1157784 A1 HK 1157784A1 HK 11112373 A HK11112373 A HK 11112373A HK 1157784 A1 HK1157784 A1 HK 1157784A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- quinoxalinedione derivatives
- quinoxalinedione
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08290564 | 2008-06-16 | ||
| PCT/EP2009/003538 WO2009152909A1 (en) | 2008-06-16 | 2009-05-19 | Quinoxalinedione derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1157784A1 true HK1157784A1 (en) | 2012-07-06 |
Family
ID=40823394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK11112373.9A HK1157784A1 (en) | 2008-06-16 | 2011-11-16 | Quinoxalinedione derivatives |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US8329698B2 (xx) |
| EP (1) | EP2285786B1 (xx) |
| JP (1) | JP5596676B2 (xx) |
| KR (1) | KR101641391B1 (xx) |
| CN (1) | CN102066342B (xx) |
| AR (1) | AR072148A1 (xx) |
| AU (1) | AU2009259754B2 (xx) |
| BR (1) | BRPI0915064B8 (xx) |
| CA (1) | CA2728018C (xx) |
| CO (1) | CO6321252A2 (xx) |
| CY (1) | CY1114737T1 (xx) |
| DK (1) | DK2285786T3 (xx) |
| EA (1) | EA020236B1 (xx) |
| EC (1) | ECSP11010760A (xx) |
| ES (1) | ES2436195T3 (xx) |
| HK (1) | HK1157784A1 (xx) |
| HR (1) | HRP20131069T1 (xx) |
| IL (1) | IL209421A (xx) |
| MX (1) | MX2010013577A (xx) |
| MY (1) | MY155695A (xx) |
| NZ (1) | NZ590503A (xx) |
| PL (1) | PL2285786T3 (xx) |
| PT (1) | PT2285786E (xx) |
| SI (1) | SI2285786T1 (xx) |
| WO (1) | WO2009152909A1 (xx) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| US8889730B2 (en) | 2012-04-10 | 2014-11-18 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
| LT2841428T (lt) | 2012-04-24 | 2018-12-10 | Vertex Pharmaceuticals Incorporated | Dnr-pk inhibitoriai |
| DK2970218T3 (en) | 2013-03-12 | 2019-03-25 | Vertex Pharma | DNA-PK inhibitors |
| JP6064062B2 (ja) | 2013-03-15 | 2017-01-18 | ファイザー・インク | Ａｍｐｋを活性化させるインダゾール化合物 |
| CN103435561B (zh) * | 2013-08-19 | 2016-08-10 | 上海交通大学 | 一种新型d-氨基酸氧化酶抑制剂及其制备和应用 |
| EP3424920B1 (en) | 2013-10-17 | 2020-04-15 | Vertex Pharmaceuticals Incorporated | Co-crystals of (s)-n-methyl-8-(1-((2'-methyl-[4,5'-bipyrimidin]-6-yl)amino)propan-2-yl)quinoline-4-carboxamide and deuterated derivatives thereof as dna-pk inhibitors |
| AU2017335648B2 (en) | 2016-09-27 | 2022-02-17 | Vertex Pharmaceuticals Incorporated | Method for treating cancer using a combination of DNA-damaging agents and DNA-PK inhibitors |
| EP3941496A4 (en) * | 2019-03-18 | 2022-11-23 | University of Washington | METHOD OF PROMOTING CELLULAR MATURATION WITH AMPK ACTIVATORS |
| CN110642798B (zh) * | 2019-11-10 | 2020-07-24 | 湖南科技学院 | 一种n-取代-1,4-二氢-2,3-喹喔啉二酮化合物的绿色合成方法 |
| US11618751B1 (en) | 2022-03-25 | 2023-04-04 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives |
| CA3178994A1 (en) | 2020-05-19 | 2021-11-25 | Iyassu Sebhat | Ampk activators |
| JP2023531726A (ja) | 2020-06-26 | 2023-07-25 | キャリーオペ，インク． | Ａｍｐｋアクチベーター |
| CN116322663A (zh) | 2020-09-30 | 2023-06-23 | 比奥维拉迪维治疗股份有限公司 | Ampk激活剂及其使用方法 |
| US11767320B2 (en) | 2020-10-02 | 2023-09-26 | Incyte Corporation | Bicyclic dione compounds as inhibitors of KRAS |
| US20240067645A1 (en) * | 2020-11-26 | 2024-02-29 | Lg Chem, Ltd. | Heterocyclic compound as diacylglycerol kinase inhibitor and use thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5631373A (en) * | 1993-11-05 | 1997-05-20 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon | Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones |
| NZ336971A (en) | 1997-02-18 | 2000-10-27 | American Home Prod | 5-Aminoalkoxy-1,4-dihydroquinoxaline-2,3-diones useful as dopamine agonists |
| EP1397134A2 (en) * | 2001-05-25 | 2004-03-17 | Boehringer Ingelheim Pharma GmbH & Co.KG | Combination of a dopamine d2-receptor agonist and tiotropium or a derivative therof for treating obstructive airways |
| CA2551639A1 (en) | 2004-01-06 | 2005-07-28 | Janssen Pharmaceutica N.V. | (3-oxo-3, 4-dihydro-quinoxalin-2-yl-amino) -benzamide derivatives and related compound as glycogen phosphorylase inhibitors for the treatment of diabetes and obesity |
| MY139645A (en) * | 2004-02-11 | 2009-10-30 | Amgen Inc | Vanilloid receptor ligands and their use in treatments |
| BRPI0711628A2 (pt) * | 2006-05-15 | 2011-12-06 | Irm Llc | composto, composição farmacêutica, uso e processo para preparação do composto |
| FR2903695B1 (fr) * | 2006-07-13 | 2008-10-24 | Merck Sante Soc Par Actions Si | Utilisation de derives d'imidazole activateurs de l'ampk, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2009
- 2009-05-19 PL PL09765489T patent/PL2285786T3/pl unknown
- 2009-05-19 BR BRPI0915064A patent/BRPI0915064B8/pt active IP Right Grant
- 2009-05-19 PT PT97654891T patent/PT2285786E/pt unknown
- 2009-05-19 NZ NZ590503A patent/NZ590503A/xx unknown
- 2009-05-19 AU AU2009259754A patent/AU2009259754B2/en active Active
- 2009-05-19 SI SI200930812T patent/SI2285786T1/sl unknown
- 2009-05-19 MX MX2010013577A patent/MX2010013577A/es active IP Right Grant
- 2009-05-19 EA EA201100007A patent/EA020236B1/ru not_active IP Right Cessation
- 2009-05-19 CN CN2009801227397A patent/CN102066342B/zh active Active
- 2009-05-19 WO PCT/EP2009/003538 patent/WO2009152909A1/en active Application Filing
- 2009-05-19 EP EP09765489.1A patent/EP2285786B1/en active Active
- 2009-05-19 CA CA2728018A patent/CA2728018C/en active Active
- 2009-05-19 US US12/997,641 patent/US8329698B2/en active Active
- 2009-05-19 KR KR1020117000992A patent/KR101641391B1/ko active IP Right Grant
- 2009-05-19 MY MYPI2010005917A patent/MY155695A/en unknown
- 2009-05-19 ES ES09765489T patent/ES2436195T3/es active Active
- 2009-05-19 JP JP2011513895A patent/JP5596676B2/ja active Active
- 2009-05-19 DK DK09765489.1T patent/DK2285786T3/da active
- 2009-06-16 AR ARP090102166A patent/AR072148A1/es active IP Right Grant
-
2010
- 2010-11-18 IL IL209421A patent/IL209421A/en active IP Right Grant
- 2010-12-14 CO CO10156748A patent/CO6321252A2/es active IP Right Grant
-
2011
- 2011-01-14 EC EC2011010760A patent/ECSP11010760A/es unknown
- 2011-11-16 HK HK11112373.9A patent/HK1157784A1/xx unknown
-
2012
- 2012-08-24 US US13/593,722 patent/US8674097B2/en active Active
-
2013
- 2013-11-08 HR HRP20131069AT patent/HRP20131069T1/hr unknown
- 2013-12-27 CY CY20131101166T patent/CY1114737T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1256310A1 (zh) | N-磺酰基吡咯衍生物 | |
| HK1157784A1 (en) | Quinoxalinedione derivatives | |
| IL210548A0 (en) | Spiroaminodihydrothiazine derivatives | |
| EP2376494A4 (en) | DIHYDROPYRIMIDOPIRYMIDINE DERIVATIVES | |
| ZA201100799B (en) | Imidazopyridin-2-one derivatives | |
| EP2376493A4 (en) | DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVE | |
| EP2380877A4 (en) | PYRIDINE-3-CARBONSÄUREAMIDDERIVAT | |
| SG10201506608RA (en) | 3-deazaneplanocin derivatives | |
| ZA201100876B (en) | Pyrrolopyridinylpyrimidin-2-ylamine derivatives | |
| EP2291078A4 (en) | OXAZOLBENZIMIDAZOLDERIVATE | |
| ZA201102449B (en) | Morpholinopurine derivatives | |
| EP2279532A4 (en) | OXAZOLBENZIMIDAZOLDERIVATE | |
| EP2269993A4 (en) | 2-aminoquinazoline DERIVATIVE | |
| IL210869A0 (en) | Imidazothiadiazoles derivatives | |
| IL208623A0 (en) | Cyclopentylacrylamide derivative | |
| IL206875A0 (en) | Bicycloamine derivative | |
| IL208336A0 (en) | Pyrisazinone derivatives | |
| ZA201100948B (en) | Acylaminobenzamide derivatives | |
| IL210164A0 (en) | Thiazolylpiperidine derivatives | |
| ZA201105050B (en) | Quinazolinamide derivatives | |
| ZA201008052B (en) | 2-phenyl-4-cyclopropyl-pyrimidine derivatives | |
| EP2292613A4 (en) | DIHYDROINDOLINONDERIVATE | |
| EP2258697A4 (en) | HYDROXYCHINOXALINCARBOXAMIDDERIVAT | |
| EP2248811A4 (en) | 2-OXOCHROMENE DERIVATIVE | |
| IL212683A0 (en) | Biphenylacetamide derivative |