HK1157249A1 - Injectable cross-linked polymeric preparations and uses thereof - Google Patents
Injectable cross-linked polymeric preparations and uses thereofInfo
- Publication number
- HK1157249A1 HK1157249A1 HK11111510.5A HK11111510A HK1157249A1 HK 1157249 A1 HK1157249 A1 HK 1157249A1 HK 11111510 A HK11111510 A HK 11111510A HK 1157249 A1 HK1157249 A1 HK 1157249A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- linked polymeric
- polymeric preparations
- injectable cross
- injectable
- preparations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/33—Fibroblasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/734—Alginic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/738—Cross-linked polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/20—Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL15577403 | 2003-05-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1157249A1 true HK1157249A1 (en) | 2012-06-29 |
Family
ID=33428272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11111510.5A HK1157249A1 (en) | 2003-05-05 | 2011-10-26 | Injectable cross-linked polymeric preparations and uses thereof |
Country Status (12)
Country | Link |
---|---|
US (9) | US20050003010A1 (xx) |
EP (2) | EP1620140B1 (xx) |
JP (2) | JP2006525405A (xx) |
KR (1) | KR101180896B1 (xx) |
CN (1) | CN100393367C (xx) |
CA (1) | CA2524356C (xx) |
DK (1) | DK1620140T3 (xx) |
ES (1) | ES2440654T3 (xx) |
HK (1) | HK1157249A1 (xx) |
IL (1) | IL170952A (xx) |
MX (1) | MXPA05011896A (xx) |
WO (1) | WO2004098669A1 (xx) |
Families Citing this family (142)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6702744B2 (en) | 2001-06-20 | 2004-03-09 | Advanced Cardiovascular Systems, Inc. | Agents that stimulate therapeutic angiogenesis and techniques and devices that enable their delivery |
US8608661B1 (en) | 2001-11-30 | 2013-12-17 | Advanced Cardiovascular Systems, Inc. | Method for intravascular delivery of a treatment agent beyond a blood vessel wall |
AU2003248750A1 (en) * | 2002-06-27 | 2004-01-19 | J. Luis Guerrero | Ventricular remodeling for artioventricular valve regurgitation |
US7361368B2 (en) | 2002-06-28 | 2008-04-22 | Advanced Cardiovascular Systems, Inc. | Device and method for combining a treatment agent and a gel |
US7641643B2 (en) | 2003-04-15 | 2010-01-05 | Abbott Cardiovascular Systems Inc. | Methods and compositions to treat myocardial conditions |
US8821473B2 (en) | 2003-04-15 | 2014-09-02 | Abbott Cardiovascular Systems Inc. | Methods and compositions to treat myocardial conditions |
ES2440654T3 (es) | 2003-05-05 | 2014-01-29 | Ben-Gurion University Of The Negev Research And Development Authority | Preparaciones poliméricas reticuladas inyectables y usos de las mismas |
EP1691747B1 (en) * | 2003-11-13 | 2012-05-23 | CardioPolymers, Inc. | Control of cardiac arrhythmias by modification of neuronal conduction within fat pads of the heart |
US8073538B2 (en) * | 2003-11-13 | 2011-12-06 | Cardio Polymers, Inc. | Treatment of cardiac arrhythmia by modification of neuronal signaling through fat pads of the heart |
EP1756272A2 (en) * | 2004-01-09 | 2007-02-28 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compounds, pharmaceutical compositions and therapeutic methods of preventing and treating diseases and disorders associated with amyloid fibril formation |
US8828433B2 (en) | 2005-04-19 | 2014-09-09 | Advanced Cardiovascular Systems, Inc. | Hydrogel bioscaffoldings and biomedical device coatings |
US20080125745A1 (en) | 2005-04-19 | 2008-05-29 | Shubhayu Basu | Methods and compositions for treating post-cardial infarction damage |
US8303972B2 (en) | 2005-04-19 | 2012-11-06 | Advanced Cardiovascular Systems, Inc. | Hydrogel bioscaffoldings and biomedical device coatings |
US8187621B2 (en) | 2005-04-19 | 2012-05-29 | Advanced Cardiovascular Systems, Inc. | Methods and compositions for treating post-myocardial infarction damage |
US9539410B2 (en) | 2005-04-19 | 2017-01-10 | Abbott Cardiovascular Systems Inc. | Methods and compositions for treating post-cardial infarction damage |
US8568761B2 (en) * | 2005-07-15 | 2013-10-29 | Cormatrix Cardiovascular, Inc. | Compositions for regenerating defective or absent myocardium |
US20070014869A1 (en) * | 2005-07-15 | 2007-01-18 | Cormatrix Cardiovascular, Inc. | Compositions for reconstruction, replacement or repair of intracardiac tissue |
US8083726B1 (en) * | 2005-09-30 | 2011-12-27 | Advanced Cardiovascular Systems, Inc. | Encapsulating cells and lumen |
PT2347775T (pt) | 2005-12-13 | 2020-07-14 | The President And Fellows Of Harvard College | Estruturas em andaime para transplante celular |
AU2007249682B2 (en) * | 2006-05-15 | 2013-05-16 | Cardiopolymers, Inc. | Post-operative control of cardiac arrhythmia by modification of neuronal signaling |
WO2007146319A2 (en) * | 2006-06-13 | 2007-12-21 | Symphony Medical, Inc. | Methods and apparatus for using polymer-based beads and hydrogels for cardiac applications |
CA2655026C (en) | 2006-06-15 | 2016-08-02 | Microvention, Inc. | Embolization device constructed from expansible polymer |
US20080085295A1 (en) * | 2006-07-14 | 2008-04-10 | Fmc Biopolymer As | Hydrogels containing low molecular weight alginates and biostructures made therefrom |
US7732190B2 (en) | 2006-07-31 | 2010-06-08 | Advanced Cardiovascular Systems, Inc. | Modified two-component gelation systems, methods of use and methods of manufacture |
US9242005B1 (en) | 2006-08-21 | 2016-01-26 | Abbott Cardiovascular Systems Inc. | Pro-healing agent formulation compositions, methods and treatments |
US20090012413A1 (en) * | 2006-09-08 | 2009-01-08 | Sabbah Hani N | Cardiac patterning for improving diastolic function |
JP5522663B2 (ja) * | 2006-09-08 | 2014-06-18 | カーディオポリマーズ, インコーポレイテッド | 全体的な心臓のサイズ変更および再形成のための心筋内パターン形成 |
US8741326B2 (en) | 2006-11-17 | 2014-06-03 | Abbott Cardiovascular Systems Inc. | Modified two-component gelation systems, methods of use and methods of manufacture |
US9005672B2 (en) | 2006-11-17 | 2015-04-14 | Abbott Cardiovascular Systems Inc. | Methods of modifying myocardial infarction expansion |
US8192760B2 (en) | 2006-12-04 | 2012-06-05 | Abbott Cardiovascular Systems Inc. | Methods and compositions for treating tissue using silk proteins |
EP2476411A1 (en) * | 2007-03-13 | 2012-07-18 | Biolinerx Ltd. | A method of promoting tissue repair |
AU2008239681B2 (en) * | 2007-04-11 | 2013-10-03 | Henry Ford Health System | Cardiac repair, resizing and reshaping using the venous system of the heart |
US20110022149A1 (en) * | 2007-06-04 | 2011-01-27 | Cox Brian J | Methods and devices for treatment of vascular defects |
US9770535B2 (en) | 2007-06-21 | 2017-09-26 | President And Fellows Of Harvard College | Scaffolds for cell collection or elimination |
IL187707A0 (en) | 2007-11-27 | 2008-11-03 | Univ Ben Gurion | Alginate scaffold in hepatectomy |
EP2266639B1 (en) | 2007-12-21 | 2016-10-05 | MicroVention, Inc. | Methods for preparing hydrogel filaments for biomedical use |
CA2715460C (en) | 2008-02-13 | 2020-02-18 | President And Fellows Of Harvard College | Continuous cell programming devices |
US9370558B2 (en) | 2008-02-13 | 2016-06-21 | President And Fellows Of Harvard College | Controlled delivery of TLR agonists in structural polymeric devices |
US20090259210A1 (en) * | 2008-04-10 | 2009-10-15 | Sabbah Hani N | Method, apparatus and kits for forming structural members within the cardiac venous system |
US8801665B2 (en) * | 2008-04-10 | 2014-08-12 | Henry Ford Health System | Apparatus and method for controlled depth of injection into myocardial tissue |
CN106974691A (zh) | 2008-05-02 | 2017-07-25 | 斯昆特医疗公司 | 用于治疗血管缺损的丝状装置 |
US9012399B2 (en) * | 2008-05-30 | 2015-04-21 | President And Fellows Of Harvard College | Controlled release of growth factors and signaling molecules for promoting angiogenesis |
GB2476624B (en) | 2008-09-30 | 2013-07-10 | Univ California | Compositions and methods for tissue repair with extracellular matrices |
ES2553762T3 (es) * | 2009-02-18 | 2015-12-11 | Cormatrix Cardiovascular, Inc. | Composiciones y métodos para prevenir la arritmia cardiaca |
WO2010120749A2 (en) | 2009-04-13 | 2010-10-21 | President And Fellow Of Harvard College | Harnessing cell dynamics to engineer materials |
US10639396B2 (en) | 2015-06-11 | 2020-05-05 | Microvention, Inc. | Polymers |
AU2010278702C1 (en) | 2009-07-31 | 2016-07-14 | Forsyth Dental Infirmary For Children | Programming of cells for tolerogenic therapies |
US9993252B2 (en) | 2009-10-26 | 2018-06-12 | Microvention, Inc. | Embolization device constructed from expansile polymer |
WO2011057002A2 (en) * | 2009-11-05 | 2011-05-12 | Sequent Medical Inc. | Multiple layer filamentary devices or treatment of vascular defects |
US9610328B2 (en) * | 2010-03-05 | 2017-04-04 | President And Fellows Of Harvard College | Enhancement of skeletal muscle stem cell engraftment by dual delivery of VEGF and IGF-1 |
EP2585053A4 (en) | 2010-06-25 | 2014-02-26 | Harvard College | COMMON RELEASE OF STIMULATING AND HEMMING FACTORS FOR THE PRODUCTION OF TEMPORARY STABILIZED AND SPATULARLY LIMITED ZONES |
EP2600901B1 (en) | 2010-08-06 | 2019-03-27 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
ES2751393T3 (es) | 2010-08-24 | 2020-03-31 | Univ California | Composiciones y métodos para la terapia cardíaca |
HRP20220796T1 (hr) | 2010-10-01 | 2022-10-14 | ModernaTX, Inc. | Ribonukleinske kiseline koje sadrže n1-metil-pseudouracil i njihove uporabe |
US11202759B2 (en) * | 2010-10-06 | 2021-12-21 | President And Fellows Of Harvard College | Injectable, pore-forming hydrogels for materials-based cell therapies |
WO2012064697A2 (en) | 2010-11-08 | 2012-05-18 | President And Fellows Of Harvard College | Materials presenting notch signaling molecules to control cell behavior |
EP2606828B1 (en) * | 2011-12-20 | 2018-04-11 | Angioclinic AG | Hyaluronic acid and its use for treating venous insufficiency and varicose veins |
CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
WO2012145431A2 (en) | 2011-04-18 | 2012-10-26 | Microvention, Inc. | Embolic devices |
EP2701753B1 (en) | 2011-04-27 | 2018-12-26 | President and Fellows of Harvard College | Cell-friendly inverse opal hydrogels for cell encapsulation, drug and protein delivery, and functional nanoparticle encapsulation |
EP2701745B1 (en) | 2011-04-28 | 2018-07-11 | President and Fellows of Harvard College | Injectable preformed macroscopic 3-dimensional scaffolds for minimally invasive administration |
US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
US8404256B2 (en) * | 2011-05-06 | 2013-03-26 | The University Of Memphis Research Foundation | Biomaterial composite composition and method of use |
JP6062426B2 (ja) | 2011-06-03 | 2017-01-18 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | インサイチュー抗原生成癌ワクチン |
WO2013036708A2 (en) | 2011-09-07 | 2013-03-14 | The Regents Of The University Of California | Compositions and methods for tissue repair with extracellular matrices |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
EP3492109B1 (en) | 2011-10-03 | 2020-03-04 | ModernaTX, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
RS63244B1 (sr) | 2011-12-16 | 2022-06-30 | Modernatx Inc | Kompozicije modifikovane mrna |
CA2859717A1 (en) | 2011-12-21 | 2013-06-27 | Bellerophon Bcm Llc | Process for manufacturing partially cross-linked alginate solution |
CN102532564B (zh) * | 2012-01-16 | 2013-09-25 | 孙珊 | 一种水凝胶及其制备方法 |
WO2013151664A1 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
US9303079B2 (en) | 2012-04-02 | 2016-04-05 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
SI2838515T1 (sl) | 2012-04-16 | 2020-07-31 | President And Fellows Of Harvard College | Mezoporozni sestavki iz silicijevega dioksida za moduliranje imunskih odgovorov |
WO2013158781A1 (en) | 2012-04-18 | 2013-10-24 | Microvention, Inc. | Embolic devices |
EP2861257B1 (en) | 2012-06-14 | 2021-12-08 | Microvention, Inc. | Polymeric treatment compositions |
US9827321B2 (en) | 2012-08-14 | 2017-11-28 | The Trustees Of The University Of Pennsylvania | Stabilizing shear-thinning hydrogels |
JP6040506B2 (ja) * | 2012-08-27 | 2016-12-07 | 国立大学法人名古屋大学 | アルギン酸の分解方法とアルギン酸および/またはその誘導体からなる組成物 |
AU2013331439B2 (en) | 2012-10-15 | 2016-05-12 | Microvention, Inc. | Polymeric treatment compositions |
PL2922554T3 (pl) | 2012-11-26 | 2022-06-20 | Modernatx, Inc. | Na zmodyfikowany na końcach |
WO2014102802A1 (en) | 2012-12-30 | 2014-07-03 | Hadasit Medical Research Services And Development Ltd. | Alginate compositions and uses thereof |
GB201304514D0 (en) * | 2013-03-13 | 2013-04-24 | Univ Birmingham | Cell delivery |
WO2014152211A1 (en) | 2013-03-14 | 2014-09-25 | Moderna Therapeutics, Inc. | Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
US9901662B2 (en) * | 2013-05-29 | 2018-02-27 | Otsuka Pharmaceutical Factory, Inc. | Adhesion preventing material |
CA2915143C (en) | 2013-06-13 | 2021-08-03 | Orgenesis Ltd. | Cell populations, methods of transdifferentiation and methods of use thereof |
US9078658B2 (en) | 2013-08-16 | 2015-07-14 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
US9955976B2 (en) | 2013-08-16 | 2018-05-01 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
CA2923029A1 (en) | 2013-09-03 | 2015-03-12 | Moderna Therapeutics, Inc. | Chimeric polynucleotides |
US20160194368A1 (en) | 2013-09-03 | 2016-07-07 | Moderna Therapeutics, Inc. | Circular polynucleotides |
CN103480037B (zh) * | 2013-09-06 | 2015-12-02 | 奚廷斐 | 用于心衰辅助治疗的可注射型海藻酸基生物材料及其制备方法 |
SG11201602503TA (en) | 2013-10-03 | 2016-04-28 | Moderna Therapeutics Inc | Polynucleotides encoding low density lipoprotein receptor |
WO2015153996A1 (en) | 2014-04-03 | 2015-10-08 | Micro Vention, Inc. | Embolic devices |
US9629635B2 (en) | 2014-04-14 | 2017-04-25 | Sequent Medical, Inc. | Devices for therapeutic vascular procedures |
WO2015160793A1 (en) | 2014-04-14 | 2015-10-22 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biodegradable, thermally responsive injectable hydrogel for treatment of ischemic cardiomyopathy |
JP6599361B2 (ja) | 2014-04-29 | 2019-10-30 | マイクロベンション インコーポレイテッド | 活性剤を含むポリマー |
US10092663B2 (en) | 2014-04-29 | 2018-10-09 | Terumo Corporation | Polymers |
US10682400B2 (en) | 2014-04-30 | 2020-06-16 | President And Fellows Of Harvard College | Combination vaccine devices and methods of killing cancer cells |
EP3169693B1 (en) | 2014-07-16 | 2022-03-09 | ModernaTX, Inc. | Chimeric polynucleotides |
US20170210788A1 (en) | 2014-07-23 | 2017-07-27 | Modernatx, Inc. | Modified polynucleotides for the production of intrabodies |
MA41296A (fr) | 2014-12-30 | 2017-11-07 | Orgenesis Ltd | Procédés de transdifférenciation et procédés d'utilisation de ceux-ci |
US11786457B2 (en) | 2015-01-30 | 2023-10-17 | President And Fellows Of Harvard College | Peritumoral and intratumoral materials for cancer therapy |
ES2855006T3 (es) | 2015-04-01 | 2021-09-23 | Univ Yale | Partículas de hierro y platino para la adherencia de productos biológicos en implantes médicos |
US20180085496A1 (en) | 2015-04-01 | 2018-03-29 | Yale University | Ferromagnetic particles bound to polymeric implants |
WO2016164705A1 (en) | 2015-04-10 | 2016-10-13 | Omar Abdel-Rahman Ali | Immune cell trapping devices and methods for making and using the same |
AU2016311504A1 (en) * | 2015-08-24 | 2018-03-08 | Jerachmiel Yori APPELBAUM | Pharmaceutical compositions and methods for the treatment of hypoxia-related diseases |
US9655842B1 (en) * | 2015-12-04 | 2017-05-23 | Covidien Lp | Injectable non-aqueous compositions and methods of treating vascular disease |
CN109072197A (zh) | 2016-02-06 | 2018-12-21 | 哈佛学院校长同事会 | 重塑造血巢以重建免疫 |
US11555177B2 (en) | 2016-07-13 | 2023-01-17 | President And Fellows Of Harvard College | Antigen-presenting cell-mimetic scaffolds and methods for making and using the same |
US10368874B2 (en) | 2016-08-26 | 2019-08-06 | Microvention, Inc. | Embolic compositions |
FR3055805B1 (fr) * | 2016-09-09 | 2020-05-15 | Assistance Publique - Hopitaux De Paris (Ap-Hp) | Biomateriau a usage therapeutique |
US11590162B2 (en) | 2016-10-07 | 2023-02-28 | University of Pittsburgh—of the Commonwealth System of Higher Education | Biodegradable, antioxidant, thermally responsive injectable hydrogel and uses therefor |
US10505870B2 (en) | 2016-11-07 | 2019-12-10 | At&T Intellectual Property I, L.P. | Method and apparatus for a responsive software defined network |
WO2018187286A1 (en) | 2017-04-03 | 2018-10-11 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | A biodegradable, porous, thermally responsive injectable hydrogel as soft tissue defect filler |
US10673751B2 (en) * | 2017-04-27 | 2020-06-02 | At&T Intellectual Property I, L.P. | Method and apparatus for enhancing services in a software defined network |
US10819606B2 (en) | 2017-04-27 | 2020-10-27 | At&T Intellectual Property I, L.P. | Method and apparatus for selecting processing paths in a converged network |
US10749796B2 (en) | 2017-04-27 | 2020-08-18 | At&T Intellectual Property I, L.P. | Method and apparatus for selecting processing paths in a software defined network |
EP3635106A4 (en) | 2017-05-08 | 2021-01-06 | Orgenesis Ltd. | TRANSDIFFERENTIAL CELL POPULATIONS AND METHOD OF USING THEM |
US10382903B2 (en) | 2017-05-09 | 2019-08-13 | At&T Intellectual Property I, L.P. | Multi-slicing orchestration system and method for service and/or content delivery |
US10257668B2 (en) | 2017-05-09 | 2019-04-09 | At&T Intellectual Property I, L.P. | Dynamic network slice-switching and handover system and method |
KR102056007B1 (ko) * | 2017-06-19 | 2019-12-13 | 순천향대학교 산학협력단 | 근원세포 분화 억제 조성물, 이를 이용한 근육 소모성 질환의 치료제 스크리닝 시스템 및 스크리닝 방법 |
US10070344B1 (en) | 2017-07-25 | 2018-09-04 | At&T Intellectual Property I, L.P. | Method and system for managing utilization of slices in a virtual network function environment |
US10576182B2 (en) | 2017-10-09 | 2020-03-03 | Microvention, Inc. | Radioactive liquid embolic |
KR102071111B1 (ko) * | 2017-10-11 | 2020-01-29 | 아주대학교산학협력단 | 성장인자 모사 펩타이드가 도입된 생체물질, 이의 제조방법 및 이의 응용 |
US10104548B1 (en) | 2017-12-18 | 2018-10-16 | At&T Intellectual Property I, L.P. | Method and apparatus for dynamic instantiation of virtual service slices for autonomous machines |
US11504335B2 (en) | 2018-06-18 | 2022-11-22 | University Of Kentucky Research Foundation | Increased cell retention in diseased site when cells encapsulated in gelatin methacrylate and polyethylene glycol diacrylate hydrogels |
CN108853147B (zh) * | 2018-07-24 | 2021-12-24 | 苏州大学 | 一种缓释外泌体的多肽纳米纤维水凝胶及其制备方法与应用 |
CN113556985B (zh) | 2019-03-15 | 2024-10-18 | 美科微先股份有限公司 | 用于治疗血管缺陷的丝装置 |
EP3908208A4 (en) | 2019-03-15 | 2022-10-19 | Sequent Medical, Inc. | FILAMENTARY DEVICES WITH A FLEXIBLE JOINT FOR THE TREATMENT OF VASCULAR ABNORMALITIES |
EP3908354A4 (en) | 2019-03-15 | 2023-04-26 | Sequent Medical, Inc. | FIBROUS DEVICES FOR TREATMENT OF VASCULAR DEFECTS |
KR102253619B1 (ko) | 2019-12-05 | 2021-05-20 | 한국철도기술연구원 | 아진공 튜브 내부 캡슐차량과 가이드와이어 사이의 마찰력 계측 실험장치 |
KR102299142B1 (ko) | 2019-12-31 | 2021-09-09 | 한국철도기술연구원 | 아진공 튜브 내부 캡슐차량 발사 진동 감쇄 시스템 |
WO2021181437A1 (en) * | 2020-03-10 | 2021-09-16 | University Of Petra | A method of preparing alginate micro-particulates |
US12070220B2 (en) | 2020-03-11 | 2024-08-27 | Microvention, Inc. | Devices having multiple permeable shells for treatment of vascular defects |
US12023034B2 (en) | 2020-03-11 | 2024-07-02 | Microvention, Inc. | Devices for treatment of vascular defects |
GB202008857D0 (en) * | 2020-06-11 | 2020-07-29 | Univ Birmingham | Fluid gel compositions |
KR102545746B1 (ko) * | 2020-12-03 | 2023-06-20 | 가톨릭대학교 산학협력단 | 유도만능줄기세포 유래 혈관세포 및 SDF1a를 발현하는 중간엽 줄기세포를 포함하는 심장 재생용 조성물 |
US12090243B2 (en) * | 2021-03-24 | 2024-09-17 | Aleo Bme, Inc. | Compositions comprising fluid gels for tissue separation |
CN117462750A (zh) * | 2022-05-07 | 2024-01-30 | 四川大学 | 具有心肌组织修复功能的抗心衰可注射水凝胶及其制备方法和应用 |
CN115475282A (zh) * | 2022-10-17 | 2022-12-16 | 中国人民解放军空军军医大学 | 一种海藻酸盐-胶原可注射复合水凝胶及其制备方法 |
CN117959494B (zh) * | 2024-03-28 | 2024-06-07 | 四川大学 | 一种双交联网络结构水凝胶及其制备方法及其用途及修复材料 |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4717713A (en) | 1983-10-31 | 1988-01-05 | Research Corporation | Controlled release liquid pharmaceutical |
US4604394A (en) * | 1984-10-01 | 1986-08-05 | Merck & Co., Inc. | Antiarrhythmic compositions and method |
US5318780A (en) * | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
US5709854A (en) * | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
EP0708662A1 (en) * | 1993-04-30 | 1996-05-01 | Massachusetts Institute Of Technology | Injectable polysaccharide-cell compositions |
DK94693D0 (da) | 1993-08-19 | 1993-08-19 | Coloplast As | Ikke-fibroest poroest materiale, saarbandage omfattende en saadan bandage samt fremgangsmaade til fremstilling af materialet |
IL114193A (en) * | 1994-06-20 | 2000-02-29 | Teva Pharma | Ophthalmic pharmaceutical compositions based on sodium alginate |
US6099876A (en) | 1994-10-11 | 2000-08-08 | Yissum Research Development Co. Of The Hebrew University Of Jerusalem | Temperature-stable liquid cells |
US5614204A (en) | 1995-01-23 | 1997-03-25 | The Regents Of The University Of California | Angiographic vascular occlusion agents and a method for hemostatic occlusion |
US6129761A (en) * | 1995-06-07 | 2000-10-10 | Reprogenesis, Inc. | Injectable hydrogel compositions |
US5924073A (en) | 1995-11-14 | 1999-07-13 | Beacon Patient Physician Association, Llc | System and method for assessing physician performance using robust multivariate techniques of statistical analysis |
CA2192773C (en) | 1995-12-15 | 2008-09-23 | Hiroaki Okada | Production of sustained-release preparation for injection |
GB9606040D0 (en) | 1996-03-22 | 1996-05-22 | Isis Innovation | Active peptide |
IL118376A0 (en) * | 1996-05-22 | 1996-09-12 | Univ Ben Gurion | Polysaccharide sponges for cell culture and transplantation |
NO305441B1 (no) * | 1996-07-12 | 1999-05-31 | Norsk Hydro As | Anvendelse av G-blokk polysakkarider |
US6642363B1 (en) | 1996-09-19 | 2003-11-04 | The Regents Of The University Of Michigan | Polymers containing polysaccharides such as alginates or modified alginates |
US5924973A (en) * | 1996-09-26 | 1999-07-20 | The Trustees Of Columbia University In The City Of New York | Method of treating a disease process in a luminal structure |
US5878147A (en) | 1996-12-31 | 1999-03-02 | Etymotic Research, Inc. | Directional microphone assembly |
CA2212300A1 (en) | 1997-08-04 | 1999-02-04 | Abdellatif Chenite | In vitro or in vivo gelfying chitosan and therapeutic uses thereof |
EP1015042A1 (en) * | 1997-09-19 | 2000-07-05 | Reprogenesis, Inc | Improved hydrogel for tissue engineering |
ES2161546T3 (es) * | 1997-11-18 | 2001-12-01 | Mokesys Ag | Revestimiento refractario de paredes tubulares. |
US6171610B1 (en) * | 1998-04-24 | 2001-01-09 | University Of Massachusetts | Guided development and support of hydrogel-cell compositions |
US6360749B1 (en) | 1998-10-09 | 2002-03-26 | Swaminathan Jayaraman | Modification of properties and geometry of heart tissue to influence heart function |
DE19904785A1 (de) | 1999-02-05 | 2000-08-10 | Ulrich Zimmermann | Verfahren zur Herstellung von stabilem Alginatmaterial |
US6592566B2 (en) * | 2000-02-03 | 2003-07-15 | Arizona Board Of Regents | Method for forming an endovascular occlusion |
US7214371B1 (en) | 2000-09-01 | 2007-05-08 | Ben-Gurion University Of The Negev Research & Development Authority | Tissue engineered biografts for repair of damaged myocardium |
ES2233570T3 (es) | 2000-11-30 | 2005-06-16 | Pfizer Products Inc. | Composicion que contiene agonistas/antagosnistas de estrogenos y testosterona para tratar un descenso en el nivel de la hormona testosterona. |
EP1451306A1 (en) | 2001-11-06 | 2004-09-01 | Medtronic, Inc. | Method and system for myocardial infarction repair |
WO2003054182A2 (en) | 2001-12-21 | 2003-07-03 | Nexia Biotechnologies, Inc. | Production of butyrylcholinesterases in transgenic mammals |
US6811777B2 (en) | 2002-04-13 | 2004-11-02 | Allan Mishra | Compositions and minimally invasive methods for treating incomplete connective tissue repair |
US20040106896A1 (en) | 2002-11-29 | 2004-06-03 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
US7641643B2 (en) | 2003-04-15 | 2010-01-05 | Abbott Cardiovascular Systems Inc. | Methods and compositions to treat myocardial conditions |
ES2340587T3 (es) | 2003-04-30 | 2010-06-07 | Drexel University | Mezclas de polimeros termogelificantes para su aplicacion en biomateriales. |
ES2440654T3 (es) | 2003-05-05 | 2014-01-29 | Ben-Gurion University Of The Negev Research And Development Authority | Preparaciones poliméricas reticuladas inyectables y usos de las mismas |
EP1756272A2 (en) | 2004-01-09 | 2007-02-28 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compounds, pharmaceutical compositions and therapeutic methods of preventing and treating diseases and disorders associated with amyloid fibril formation |
-
2004
- 2004-05-04 ES ES04731094.1T patent/ES2440654T3/es not_active Expired - Lifetime
- 2004-05-04 CA CA2524356A patent/CA2524356C/en not_active Expired - Fee Related
- 2004-05-04 CN CNB2004800192010A patent/CN100393367C/zh not_active Expired - Fee Related
- 2004-05-04 WO PCT/IL2004/000371 patent/WO2004098669A1/en active Search and Examination
- 2004-05-04 EP EP04731094.1A patent/EP1620140B1/en not_active Expired - Lifetime
- 2004-05-04 MX MXPA05011896A patent/MXPA05011896A/es active IP Right Grant
- 2004-05-04 DK DK04731094.1T patent/DK1620140T3/da active
- 2004-05-04 JP JP2006507619A patent/JP2006525405A/ja active Pending
- 2004-05-04 KR KR1020057020917A patent/KR101180896B1/ko active IP Right Grant
- 2004-05-04 EP EP10013184.6A patent/EP2314327B2/en not_active Expired - Lifetime
- 2004-05-05 US US10/840,008 patent/US20050003010A1/en not_active Abandoned
-
2005
- 2005-09-19 IL IL170952A patent/IL170952A/en active IP Right Grant
- 2005-09-19 US US11/229,119 patent/US8168612B2/en not_active Expired - Fee Related
-
2009
- 2009-12-24 US US12/647,280 patent/US20100190741A1/en not_active Abandoned
- 2009-12-24 US US12/647,295 patent/US8168613B2/en not_active Expired - Fee Related
- 2009-12-24 US US12/647,257 patent/US8110561B2/en not_active Expired - Fee Related
-
2011
- 2011-06-15 JP JP2011132761A patent/JP5492147B2/ja not_active Expired - Fee Related
- 2011-10-26 HK HK11111510.5A patent/HK1157249A1/xx not_active IP Right Cessation
-
2012
- 2012-03-26 US US13/430,020 patent/US8461132B2/en not_active Expired - Fee Related
- 2012-03-26 US US13/429,997 patent/US8455463B2/en not_active Expired - Fee Related
-
2013
- 2013-05-01 US US13/874,837 patent/US8993538B2/en not_active Expired - Fee Related
- 2013-05-14 US US13/893,567 patent/US9006213B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1157249A1 (en) | Injectable cross-linked polymeric preparations and uses thereof | |
TWI340606B (en) | Polymer compound and polymer luminous element using the same | |
HK1084883A1 (en) | 2-cyanopyrrolopyrimidines and pharmaceutical uses thereof | |
EP1636334A4 (en) | RECOMBINANT ANTI-CD30 ANTIBODIES AND USES THEREOF | |
ZA200603882B (en) | Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides | |
IL175491A0 (en) | Substituted benzimidazole-, benztriazole-, and benzimidazolone-o-glucosides | |
EP1539941A4 (en) | ADZYMES AND THEIR USES | |
IL207953A0 (en) | Gastrin - releasing peptide compounds and methods utilizing the same | |
AU2003241788A1 (en) | Polymer and polymeric luminescent element comprising the same | |
AU2003256217A8 (en) | New polymers and applications | |
HK1088837A1 (en) | Clk-peptide and slk-peptide | |
GB0428391D0 (en) | Connection and connection part | |
EP1697140A4 (en) | STRIP AND CUTTING CORRECTION | |
AU2003244054A8 (en) | Polymer and polymeric luminescent element comprising the same | |
IL165112A0 (en) | Variant integrinpolypeptides and thereof | |
IL156263A0 (en) | Livin-derived peptides, compositions and uses thereof | |
AU2003272011A8 (en) | Solid and semi-solid polymeric ionic conjugates | |
GB0324457D0 (en) | Modified peptides and their uses | |
HK1209050A1 (en) | Survivin-derived peptides and use thereof | |
GB0228525D0 (en) | Polymers and their use | |
AU2003250881A1 (en) | Polymeric blends and use thereof | |
GB0317376D0 (en) | Immunogenic protein and uses thereof | |
EP1694845A4 (en) | ANTICARCINOMIC ANTIBODIES AND USES THEREOF | |
EP1660088A4 (en) | PYRIDOMORPHINANES, PYRIDAZINOMORPHINANES AND USE THEREOF | |
EP1487547A4 (en) | MEDIUM FOR PHYSICAL INTERACTION AND ITS RELATED USES |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AM43 | Amendment of standard patent following opposition or revocation proceedings in the designated patent office (acc. sect 43 patent ordinance) | ||
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20190504 |