HK1155450A1 - Tertiary amine derivatives as phosphodiesterase-4 inhibitors -4 - Google Patents

Tertiary amine derivatives as phosphodiesterase-4 inhibitors -4

Info

Publication number
HK1155450A1
HK1155450A1 HK11109767.9A HK11109767A HK1155450A1 HK 1155450 A1 HK1155450 A1 HK 1155450A1 HK 11109767 A HK11109767 A HK 11109767A HK 1155450 A1 HK1155450 A1 HK 1155450A1
Authority
HK
Hong Kong
Prior art keywords
phosphodiesterase
inhibitors
tertiary amine
amine derivatives
derivatives
Prior art date
Application number
HK11109767.9A
Other languages
English (en)
Chinese (zh)
Inventor
．裡茲
．阿曼尼
．佩雷托
．拉伯樂達
Original Assignee
奇斯藥製品公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 奇斯藥製品公司 filed Critical 奇斯藥製品公司
Publication of HK1155450A1 publication Critical patent/HK1155450A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
HK11109767.9A 2008-04-14 2011-09-16 Tertiary amine derivatives as phosphodiesterase-4 inhibitors -4 HK1155450A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08007284A EP2110375A1 (de) 2008-04-14 2008-04-14 Phosphodiesterase-4-Hemmer der Tertiäraminklasse
PCT/EP2009/002242 WO2009127320A1 (en) 2008-04-14 2009-03-27 Tertiary amine derivatives as phosphodiesterase-4 inhibitors

Publications (1)

Publication Number Publication Date
HK1155450A1 true HK1155450A1 (en) 2012-05-18

Family

ID=39731427

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11109767.9A HK1155450A1 (en) 2008-04-14 2011-09-16 Tertiary amine derivatives as phosphodiesterase-4 inhibitors -4

Country Status (13)

Country Link
US (1) US7820698B2 (de)
EP (2) EP2110375A1 (de)
JP (1) JP5492190B2 (de)
KR (1) KR101208193B1 (de)
CN (1) CN102007117B (de)
AU (1) AU2009238014B2 (de)
BR (1) BRPI0907267A2 (de)
CA (1) CA2721240A1 (de)
EA (1) EA018069B1 (de)
HK (1) HK1155450A1 (de)
MX (1) MX2010011016A (de)
WO (1) WO2009127320A1 (de)
ZA (1) ZA201007317B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2022783A1 (de) 2007-08-08 2009-02-11 CHIESI FARMACEUTICI S.p.A. 1-Phenyl-2-Pyridinylalkyl-Alkoholderivate als Phosphodiesterasehemmer
EP2216327A1 (de) 2009-02-06 2010-08-11 CHIESI FARMACEUTICI S.p.A. (1-Phenyl-2-Pyridin-4-yl)ethyl-benzoate als Phosphodiesterasehemmer
CN103052378A (zh) 2010-08-03 2013-04-17 奇斯药制品公司 包含磷酸二酯酶抑制剂的药物制剂
CN106946848B (zh) 2011-06-06 2022-01-04 奇斯药制品公司 作为磷酸二酯酶抑制剂的1-苯基-2-吡啶基烷基醇的衍生物
CN103827088B (zh) 2011-09-26 2017-10-13 奇斯药制品公司 作为磷酸二酯酶抑制剂的1‑苯基‑2‑吡啶基烷基醇的衍生物
BR112014029642A2 (pt) * 2012-06-04 2017-06-27 Chiesi Farm Spa composto, combinação de um composto, composição farmacêutica, uso de um composto, dispositivo e kit
KR20150090253A (ko) 2012-12-05 2015-08-05 키에시 파르마슈티시 엣스. 피. 에이. Pde4-억제제로서 페닐에틸피리딘 유도체
PL2928869T3 (pl) 2012-12-05 2019-08-30 Chiesi Farmaceutici S.P.A. Pochodne alkoholu 1-fenylo-2-pirydynyloalkilowego jako inhibitory fosfodiesterazy
EP2928880B1 (de) 2012-12-05 2018-02-14 Chiesi Farmaceutici S.p.A. Phenylethylpyridin derivate als pde4-inhibitoren und muscarin rezeptor antagonisten
WO2014086855A1 (en) 2012-12-05 2014-06-12 Chiesi Farmaceutici S.P.A. Phenylethylpyridine derivatives as pde4-inhibitors
US9427376B2 (en) 2013-10-10 2016-08-30 Chiesi Farmaceutici S.P.A. Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient
WO2017089347A1 (en) 2015-11-25 2017-06-01 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and pharmaceutical compositions for the treatment of braf inhibitor resistant melanomas

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ527081A (en) * 2001-01-22 2006-03-31 Memory Pharm Corp Aniline derivatives useful as phosphodiesterase 4 inhibitors
MXPA05000827A (es) * 2002-07-19 2005-08-29 Memory Pharm Corp Inhibidores de fosfodiesterasa 4, incluyendo analogos de anilina y difenilamina n-sustituidos.
CN100513397C (zh) * 2002-11-19 2009-07-15 记忆药物公司 磷酸二酯酶4抑制剂
EP1443330A1 (de) * 2003-02-03 2004-08-04 Gilson Sas Verfahren, Rack und Vorrichtung zur Vorbereitung von Proben für analytische Zwecke
MY141255A (en) * 2003-12-11 2010-03-31 Memory Pharm Corp Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs
EP1888528A2 (de) 2005-06-10 2008-02-20 Memory Pharmaceuticals Corporation Phosphodiesterase-4-inhibitoren
WO2008006509A1 (en) * 2006-07-14 2008-01-17 Chiesi Farmaceutici S.P.A. Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors
DK2049556T3 (da) * 2006-08-09 2013-08-12 Basilea Pharmaceutica Ag Nye makrolider anvendelige mod inflammatoriske og allergiske sygdomme

Also Published As

Publication number Publication date
US7820698B2 (en) 2010-10-26
EP2268632B1 (de) 2012-08-08
WO2009127320A1 (en) 2009-10-22
EA201001481A1 (ru) 2011-06-30
EP2110375A1 (de) 2009-10-21
US20090258905A1 (en) 2009-10-15
KR101208193B1 (ko) 2012-12-04
AU2009238014B2 (en) 2013-07-18
CN102007117B (zh) 2014-06-25
AU2009238014A1 (en) 2009-10-22
JP2011517687A (ja) 2011-06-16
CN102007117A (zh) 2011-04-06
KR20100128330A (ko) 2010-12-07
JP5492190B2 (ja) 2014-05-14
MX2010011016A (es) 2010-11-09
EP2268632A1 (de) 2011-01-05
ZA201007317B (en) 2012-01-25
EA018069B1 (ru) 2013-05-30
CA2721240A1 (en) 2009-10-22
BRPI0907267A2 (pt) 2015-07-21

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20190327