HK1155170A1 - Pyridine compounds - Google Patents

Pyridine compounds

Info

Publication number
HK1155170A1
HK1155170A1 HK11109503.8A HK11109503A HK1155170A1 HK 1155170 A1 HK1155170 A1 HK 1155170A1 HK 11109503 A HK11109503 A HK 11109503A HK 1155170 A1 HK1155170 A1 HK 1155170A1
Authority
HK
Hong Kong
Prior art keywords
pyridine compounds
pyridine
compounds
Prior art date
Application number
HK11109503.8A
Other languages
English (en)
Chinese (zh)
Inventor
Bernard Christophe Barlaam
Kevin Michael Foote
Patrick Ple
Clifford David Jones
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1155170A1 publication Critical patent/HK1155170A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK11109503.8A 2008-06-17 2011-09-08 Pyridine compounds HK1155170A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7305508P 2008-06-17 2008-06-17
PCT/GB2009/050675 WO2009153589A1 (en) 2008-06-17 2009-06-15 Pyridine compounds

Publications (1)

Publication Number Publication Date
HK1155170A1 true HK1155170A1 (en) 2012-05-11

Family

ID=40896110

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11109503.8A HK1155170A1 (en) 2008-06-17 2011-09-08 Pyridine compounds

Country Status (18)

Country Link
US (1) US8569298B2 (ru)
EP (1) EP2303861B1 (ru)
JP (1) JP5551689B2 (ru)
KR (1) KR101695501B1 (ru)
CN (1) CN102124000B (ru)
AU (1) AU2009261764B2 (ru)
BR (1) BRPI0914927B8 (ru)
CA (1) CA2726508C (ru)
CR (1) CR11854A (ru)
DO (1) DOP2010000390A (ru)
EA (1) EA020807B1 (ru)
EC (1) ECSP10010695A (ru)
ES (1) ES2472323T3 (ru)
HK (1) HK1155170A1 (ru)
IL (1) IL209727A0 (ru)
MX (1) MX2010014057A (ru)
WO (1) WO2009153589A1 (ru)
ZA (1) ZA201100388B (ru)

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US20140155410A1 (en) * 2008-10-27 2014-06-05 Glaxosmithkline Llc Pyrazolylaminopyridines as inhibitors of fak
JO3067B1 (ar) * 2008-10-27 2017-03-15 Glaxosmithkline Llc بيرميدينات بيرازولو امينو كمثبطات ل fak
WO2010068947A2 (en) * 2008-12-12 2010-06-17 H. Lee Moffitt Cancer Center And Research Institute, Inc. Nuclear export inhibitors of topoisomerase ii alpha
PL2464645T3 (pl) 2009-07-27 2017-12-29 Gilead Sciences, Inc. Skondensowane heterocykliczne związki jako modulatory kanałów jonowych
CN103003264B (zh) 2010-05-21 2014-08-06 切米利亚股份公司 嘧啶衍生物
CN103313697B (zh) 2010-06-29 2016-06-01 维瑞斯特姆股份有限公司 激酶抑制剂的口服制剂
AU2011280031B2 (en) * 2010-06-30 2015-09-10 Verastem, Inc. Synthesis and use of Kinase inhibitors
CN103096977B (zh) 2010-07-02 2017-02-15 吉利德科学公司 作为离子通道调节剂的稠杂环化合物
US20120244141A1 (en) 2010-09-28 2012-09-27 Boehringer Ingelheim International Gmbh Stratification of cancer patients for susceptibility to therapy with PTK2 inhibitors
CN103476413B (zh) * 2011-01-26 2016-03-16 葛兰素史密斯克莱知识产权有限公司 组合
US20130324532A1 (en) 2011-02-17 2013-12-05 Cancer Therapeutics Crc Pty Limited Fak inhibitors
DK2675794T3 (da) 2011-02-17 2019-05-06 Cancer Therapeutics Crc Pty Ltd Selektive fak-inhibitorer
JP5886411B2 (ja) 2011-03-24 2016-03-16 ノビガ・リサーチ・エービーNoviga Research AB 新規のピリミジン誘導体
MX361350B (es) 2011-05-10 2018-12-04 Gilead Sciences Inc Compuestos heterocíclicos fusionados como moduladores del canal de sodio.
NO3175985T3 (ru) 2011-07-01 2018-04-28
TW201837023A (zh) 2011-07-01 2018-10-16 美商基利科學股份有限公司 作為離子通道調節劑之稠合雜環化合物
SG10201507714XA (en) 2012-03-16 2015-10-29 Axikin Pharmaceuticals Inc 3,5-diaminopyrazole kinase inhibitors
NZ631142A (en) 2013-09-18 2016-03-31 Axikin Pharmaceuticals Inc Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors
WO2015193765A1 (en) * 2014-06-17 2015-12-23 Pfizer Inc. Substituted dihydroisoquinolinone compounds
US9442005B2 (en) 2014-07-30 2016-09-13 Corning Optical Communications LLC Non-contact methods of measuring insertion loss in optical fiber connectors
CN107250116B (zh) 2014-12-23 2020-10-27 艾士盟医疗公司 3,5-二氨基吡唑激酶抑制剂
GB201510010D0 (en) 2015-06-09 2015-07-22 King S College London PDD and BPD compounds
JP2018519327A (ja) 2015-06-29 2018-07-19 ベラステム・インコーポレーテッドVerastem,Inc. 治療用組成物、組合せ物および使用の方法
GB201514928D0 (en) 2015-08-21 2015-10-07 King S College London PDD compounds
US20180339985A1 (en) 2015-08-21 2018-11-29 Femtogenix Limited Pdd compounds
IL302719A (en) 2018-02-28 2023-07-01 Basf Se Use of N-functional alkoxy pyrazole compounds as nitrification inhibitors
WO2019166558A1 (en) 2018-02-28 2019-09-06 Basf Se Use of pyrazole propargyl ethers as nitrification inhibitors
RU2020133451A (ru) 2018-03-12 2022-04-12 Инститьют Насьонал Де Ла Санте Et De La Решерш Медикаль (Инсерм) Применение терапевтически эффективной комбинации химиотерапиии и ингибитора контрольной точки иммунного ответа с миметиком ограничения калорийности для лечения рака
CN108912095B (zh) * 2018-08-09 2019-08-20 广州安岩仁医药科技有限公司 苯并咪唑类化合物及其制备方法和应用
JP2022552019A (ja) 2019-10-18 2022-12-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 病的血管障害の治療のための作用物質としての3-フェニルスルホニル-キノリン誘導体
AR125955A1 (es) 2021-05-21 2023-08-30 Basf Se Uso de un compuesto de alcoxi pirazol n-funcionalizado como inhibidor de nitrificación

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0004890D0 (en) * 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0305929D0 (en) 2003-03-14 2003-04-23 Novartis Ag Organic compounds
DE10336184A1 (de) 2003-08-07 2005-02-24 Bayer Materialscience Ag Neue Katalysatoren für die selektive Isocyanatdimerisierung
WO2005016894A1 (en) * 2003-08-15 2005-02-24 Novartis Ag 2, 4-pyrimidinediamines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders
BRPI0512342A (pt) 2004-06-21 2008-03-04 Pharmacia & Upjohn Co Llc métodos para aumento ósseo
GB0419160D0 (en) 2004-08-27 2004-09-29 Novartis Ag Organic compounds
GB0419161D0 (en) * 2004-08-27 2004-09-29 Novartis Ag Organic compounds
ATE519759T1 (de) 2004-12-30 2011-08-15 Exelixis Inc Pyrimidinderivate als kinasemodulatoren und anwendungsverfahren
US8722884B2 (en) * 2005-12-01 2014-05-13 Verastem, Inc. Pyrimidine derivatives for the treatment of abnormal cell growth
JP4332590B2 (ja) 2005-12-21 2009-09-16 ファイザー・プロダクツ・インク 異常細胞増殖を治療するためのピリミジン誘導体
PL2091918T3 (pl) 2006-12-08 2015-02-27 Novartis Ag Związki i kompozycje jako inhibitory kinazy białkowej
EP2134689B1 (en) * 2007-03-16 2014-04-23 The Scripps Research Institute Inhibitors of focal adhesion kinase
WO2009012283A1 (en) * 2007-07-17 2009-01-22 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
WO2009105498A1 (en) * 2008-02-19 2009-08-27 Smithkline Beecham Corporation Anilinopyridines as inhibitors of fak

Also Published As

Publication number Publication date
ES2472323T3 (es) 2014-06-30
CN102124000B (zh) 2014-09-17
CA2726508A1 (en) 2009-12-23
EA201100032A1 (ru) 2012-01-30
EA020807B1 (ru) 2015-01-30
KR20110023884A (ko) 2011-03-08
JP5551689B2 (ja) 2014-07-16
JP2011524411A (ja) 2011-09-01
BRPI0914927B8 (pt) 2021-05-25
US20110166139A1 (en) 2011-07-07
ZA201100388B (en) 2011-10-26
AU2009261764A1 (en) 2009-12-23
EP2303861A1 (en) 2011-04-06
KR101695501B1 (ko) 2017-01-11
BRPI0914927B1 (pt) 2020-10-06
CN102124000A (zh) 2011-07-13
US8569298B2 (en) 2013-10-29
AU2009261764B2 (en) 2013-01-10
CA2726508C (en) 2016-06-07
BRPI0914927A2 (pt) 2017-06-20
CR11854A (es) 2011-02-25
MX2010014057A (es) 2011-03-21
IL209727A0 (en) 2011-02-28
EP2303861B1 (en) 2014-04-23
DOP2010000390A (es) 2011-01-15
ECSP10010695A (es) 2011-01-31
WO2009153589A1 (en) 2009-12-23

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