HK1151323A1 - Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs hc cdr1cdr2cdr3 lc cdr1cdr2cdr3 - Google Patents

Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs hc cdr1cdr2cdr3 lc cdr1cdr2cdr3

Info

Publication number
HK1151323A1
HK1151323A1 HK11105221.7A HK11105221A HK1151323A1 HK 1151323 A1 HK1151323 A1 HK 1151323A1 HK 11105221 A HK11105221 A HK 11105221A HK 1151323 A1 HK1151323 A1 HK 1151323A1
Authority
HK
Hong Kong
Prior art keywords
cdr1
cdr2
novel
cdr3
libraries
Prior art date
Application number
HK11105221.7A
Other languages
English (en)
Chinese (zh)
Inventor
Robert C Ladner
Original Assignee
Dyax Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyax Corp filed Critical Dyax Corp
Publication of HK1151323A1 publication Critical patent/HK1151323A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK11105221.7A 2008-04-24 2011-05-25 Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs hc cdr1cdr2cdr3 lc cdr1cdr2cdr3 HK1151323A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4752908P 2008-04-24 2008-04-24
PCT/US2009/041688 WO2009132287A2 (en) 2008-04-24 2009-04-24 Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs

Publications (1)

Publication Number Publication Date
HK1151323A1 true HK1151323A1 (en) 2012-01-27

Family

ID=41217437

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11105221.7A HK1151323A1 (en) 2008-04-24 2011-05-25 Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs hc cdr1cdr2cdr3 lc cdr1cdr2cdr3

Country Status (11)

Country Link
US (4) US9388510B2 (de)
EP (1) EP2281078B1 (de)
JP (1) JP5780951B2 (de)
AU (1) AU2009240481B2 (de)
CA (3) CA3049612C (de)
CY (1) CY1116306T1 (de)
DK (1) DK2281078T3 (de)
ES (1) ES2528963T3 (de)
HK (1) HK1151323A1 (de)
PT (1) PT2281078E (de)
WO (1) WO2009132287A2 (de)

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US9873957B2 (en) 2008-03-13 2018-01-23 Dyax Corp. Libraries of genetic packages comprising novel HC CDR3 designs
DK2281078T3 (en) 2008-04-24 2015-02-02 Dyax Corp LIBRARIES OF RE-PACKAGES INCLUDING UNKNOWN HC-CDR1, -CDR2 AND -CDR3 AND UNKNOWN LC-CDR1, -CDR2 AND-CDR3 DESIGNS
KR101895245B1 (ko) 2010-03-31 2018-09-05 에이전시 포 사이언스, 테크놀로지 앤드 리서치 양친매성 선형 펩티드/펩토이드 및 이를 포함하는 히드로겔
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US9120841B2 (en) * 2012-09-28 2015-09-01 Agency For Science, Technology And Research Amphiphilic linear peptidepeptoid and hydrogel comprising the same
CN105073781A (zh) 2013-01-11 2015-11-18 加州生物医学研究所 牛融合抗体
CN105593242B (zh) * 2013-07-11 2020-11-06 斯克利普斯研究所 卷曲螺旋免疫球蛋白融合蛋白及其组合物
EP3022221B1 (de) 2013-07-18 2021-09-15 Taurus Biosciences, LLC Humanisierte antikörper mit ultralangen komplementaritätsbestimmenden regionen
EP3293293A1 (de) * 2016-09-08 2018-03-14 Italfarmaco SpA Hc-cdr3-only-bibliotheken mit verringerter kombinatorischer redundanz und optimierter schleifenlängenverteilung
SG10201913144TA (en) 2017-07-11 2020-03-30 Compass Therapeutics Llc Agonist antibodies that bind human cd137 and uses thereof
WO2019089753A2 (en) 2017-10-31 2019-05-09 Compass Therapeutics Llc Cd137 antibodies and pd-1 antagonists and uses thereof
WO2019099454A2 (en) * 2017-11-15 2019-05-23 Philippe Valadon Highly functional antibody libraries
EP3713961A2 (de) 2017-11-20 2020-09-30 Compass Therapeutics LLC Cd137-antikörper und tumorantigenbindende antikörper sowie deren verwendung
MX2021005594A (es) 2018-11-13 2021-10-22 Compass Therapeutics Llc Constructos multiespecificos de union contra moleculas de puntos de control y usos de los mismos.
CN113912675B (zh) * 2021-09-23 2023-04-11 中国药科大学 一种具有镇痛活性的蜈蚣多肽及其应用

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Also Published As

Publication number Publication date
US20160355571A1 (en) 2016-12-08
US9388510B2 (en) 2016-07-12
CA2968164A1 (en) 2009-10-29
US20110172125A1 (en) 2011-07-14
CA3049612A1 (en) 2009-10-29
JP5780951B2 (ja) 2015-09-16
CA3049612C (en) 2023-01-10
CA2722409C (en) 2017-12-12
CY1116306T1 (el) 2017-02-08
EP2281078A2 (de) 2011-02-09
US10683342B2 (en) 2020-06-16
ES2528963T3 (es) 2015-02-13
DK2281078T3 (en) 2015-02-02
JP2011518565A (ja) 2011-06-30
WO2009132287A2 (en) 2009-10-29
US20230340697A1 (en) 2023-10-26
AU2009240481B2 (en) 2015-07-30
US20200347117A1 (en) 2020-11-05
EP2281078B1 (de) 2014-10-22
US11598024B2 (en) 2023-03-07
CA2968164C (en) 2019-08-20
EP2281078A4 (de) 2011-07-20
PT2281078E (pt) 2015-02-05
WO2009132287A3 (en) 2010-01-28
AU2009240481A1 (en) 2009-10-29
CA2722409A1 (en) 2009-10-29

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