HK1142608A1 - 5-pyridinone substituted indazoles and pharmaceutical compositions thereof 5- - Google Patents
5-pyridinone substituted indazoles and pharmaceutical compositions thereof 5-Info
- Publication number
- HK1142608A1 HK1142608A1 HK10109173.8A HK10109173A HK1142608A1 HK 1142608 A1 HK1142608 A1 HK 1142608A1 HK 10109173 A HK10109173 A HK 10109173A HK 1142608 A1 HK1142608 A1 HK 1142608A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pharmaceutical compositions
- substituted indazoles
- pyridinone substituted
- pyridinone
- indazoles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95120107P | 2007-07-21 | 2007-07-21 | |
PCT/US2008/070535 WO2009015037A2 (fr) | 2007-07-21 | 2008-07-18 | Indazoles substitués par du 5-pyridinone |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1142608A1 true HK1142608A1 (en) | 2010-12-10 |
Family
ID=40282093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK10109173.8A HK1142608A1 (en) | 2007-07-21 | 2010-09-24 | 5-pyridinone substituted indazoles and pharmaceutical compositions thereof 5- |
Country Status (13)
Country | Link |
---|---|
US (1) | US8273770B2 (fr) |
EP (1) | EP2176251B1 (fr) |
JP (1) | JP2010534248A (fr) |
KR (1) | KR20100044225A (fr) |
CN (1) | CN101861311A (fr) |
AT (1) | ATE544759T1 (fr) |
AU (1) | AU2008279321B2 (fr) |
BR (1) | BRPI0814772A2 (fr) |
CA (1) | CA2693377A1 (fr) |
ES (1) | ES2382982T3 (fr) |
HK (1) | HK1142608A1 (fr) |
NZ (1) | NZ582586A (fr) |
WO (1) | WO2009015037A2 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2009007337A (es) * | 2007-01-10 | 2009-07-15 | Albany Molecular Res Inc | Indazoles sustituidos con 5-piridinona. |
CN101861311A (zh) | 2007-07-21 | 2010-10-13 | 阿尔巴尼分子研究公司 | 5-吡啶酮取代的吲唑 |
CA2727055C (fr) | 2008-01-11 | 2016-12-20 | Albany Molecular Research, Inc. | Pyridoindoles (1-azinone)-substitues en tant qu'antagonistes mch |
WO2011003012A1 (fr) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Antagonistes de mch-1 azapolycycles substitués par azinone, leurs procédés de fabrication et leur utilisation |
US9073925B2 (en) | 2009-07-01 | 2015-07-07 | Albany Molecular Research, Inc. | Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof |
WO2011003007A1 (fr) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Antagonistes de mch-1 dazabicycloalcane-indole et dazabicycloalcane-pyrrolo-pyridine, procédés de préparation, et utilisation de ceux-ci |
EP2448585B1 (fr) * | 2009-07-01 | 2014-01-01 | Albany Molecular Research, Inc. | Antagonistes de mch-1 d azépino[b]indole et pyrido-pyrrolo-azépine azinone-substitué, procédés de préparation, et utilisation de ceux-ci |
US8993765B2 (en) | 2010-12-21 | 2015-03-31 | Albany Molecular Research, Inc. | Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof |
WO2012088038A2 (fr) | 2010-12-21 | 2012-06-28 | Albany Molecular Research, Inc. | Antagonistes de mch-1 consistant en tétrahydro-carbolines substituées par pipérazinone, leurs procédés de fabrication et utilisations |
BR112014007603A2 (pt) | 2011-09-30 | 2017-06-13 | Glaxosmithkline Llc | métodos de tratamento do câncer |
CN107011283A (zh) * | 2017-05-31 | 2017-08-04 | 湖南华腾制药有限公司 | 一种甲硫基取代苯并[d]恶唑衍生物的制备方法 |
US11242334B2 (en) | 2017-08-22 | 2022-02-08 | Js Innopharm (Shanghai) Ltd. | Heterocyclic compounds as kinase inhibitors, compositions comprising the heterocyclic compound, and methods of use thereof |
WO2020169058A1 (fr) * | 2019-02-21 | 2020-08-27 | 杭州阿诺生物医药科技有限公司 | Composé antagoniste de pd-l1 |
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WO2006017257A2 (fr) | 2004-07-12 | 2006-02-16 | Phenomix Corporation | Derives d'acetidinone |
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KR20090097214A (ko) * | 2007-01-10 | 2009-09-15 | 알바니 몰레큘라 리써치, 인크. | 5-푸로피리디논 치환된 인다졸 |
MX2009007337A (es) | 2007-01-10 | 2009-07-15 | Albany Molecular Res Inc | Indazoles sustituidos con 5-piridinona. |
CN101861311A (zh) | 2007-07-21 | 2010-10-13 | 阿尔巴尼分子研究公司 | 5-吡啶酮取代的吲唑 |
-
2008
- 2008-07-18 CN CN200880107571A patent/CN101861311A/zh active Pending
- 2008-07-18 NZ NZ582586A patent/NZ582586A/en not_active IP Right Cessation
- 2008-07-18 WO PCT/US2008/070535 patent/WO2009015037A2/fr active Application Filing
- 2008-07-18 JP JP2010518311A patent/JP2010534248A/ja active Pending
- 2008-07-18 ES ES08796320T patent/ES2382982T3/es active Active
- 2008-07-18 EP EP08796320A patent/EP2176251B1/fr not_active Not-in-force
- 2008-07-18 AU AU2008279321A patent/AU2008279321B2/en not_active Ceased
- 2008-07-18 KR KR1020107003768A patent/KR20100044225A/ko not_active Application Discontinuation
- 2008-07-18 CA CA2693377A patent/CA2693377A1/fr not_active Abandoned
- 2008-07-18 AT AT08796320T patent/ATE544759T1/de active
- 2008-07-18 BR BRPI0814772-8A2A patent/BRPI0814772A2/pt not_active IP Right Cessation
- 2008-07-18 US US12/176,144 patent/US8273770B2/en not_active Expired - Fee Related
-
2010
- 2010-09-24 HK HK10109173.8A patent/HK1142608A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NZ582586A (en) | 2011-12-22 |
AU2008279321A1 (en) | 2009-01-29 |
CN101861311A (zh) | 2010-10-13 |
US20090082359A1 (en) | 2009-03-26 |
WO2009015037A3 (fr) | 2009-04-30 |
US8273770B2 (en) | 2012-09-25 |
AU2008279321B2 (en) | 2013-08-01 |
JP2010534248A (ja) | 2010-11-04 |
ES2382982T3 (es) | 2012-06-15 |
ATE544759T1 (de) | 2012-02-15 |
WO2009015037A2 (fr) | 2009-01-29 |
EP2176251A2 (fr) | 2010-04-21 |
KR20100044225A (ko) | 2010-04-29 |
CA2693377A1 (fr) | 2009-01-29 |
BRPI0814772A2 (pt) | 2015-03-03 |
EP2176251B1 (fr) | 2012-02-08 |
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