HK1140199A1 - Novel carbapenem derivatives - Google Patents

Novel carbapenem derivatives

Info

Publication number
HK1140199A1
HK1140199A1 HK10106343.9A HK10106343A HK1140199A1 HK 1140199 A1 HK1140199 A1 HK 1140199A1 HK 10106343 A HK10106343 A HK 10106343A HK 1140199 A1 HK1140199 A1 HK 1140199A1
Authority
HK
Hong Kong
Prior art keywords
carbapenem derivatives
novel carbapenem
novel
derivatives
carbapenem
Prior art date
Application number
HK10106343.9A
Other languages
English (en)
Inventor
Yanyan Dong
Zhenhua Huang
Original Assignee
Xuanzhu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xuanzhu Pharma Co Ltd filed Critical Xuanzhu Pharma Co Ltd
Publication of HK1140199A1 publication Critical patent/HK1140199A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK10106343.9A 2007-06-28 2010-06-29 Novel carbapenem derivatives HK1140199A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN200710015310 2007-06-28
PCT/CN2008/071446 WO2009000210A1 (fr) 2007-06-28 2008-06-26 Nouveaux dérivés de carbapénème

Publications (1)

Publication Number Publication Date
HK1140199A1 true HK1140199A1 (en) 2010-10-08

Family

ID=40185205

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10106343.9A HK1140199A1 (en) 2007-06-28 2010-06-29 Novel carbapenem derivatives

Country Status (6)

Country Link
US (1) US8293895B2 (xx)
EP (1) EP2177522B1 (xx)
JP (1) JP5406181B2 (xx)
CN (2) CN101720326B (xx)
HK (1) HK1140199A1 (xx)
WO (1) WO2009000210A1 (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8318716B2 (en) * 2009-12-31 2012-11-27 Kbp Biosciences Co., Ltd. Carbapenem derivatives
CN102690242A (zh) * 2010-02-11 2012-09-26 山东轩竹医药科技有限公司 含有胺基甲酰基杂环的碳青霉烯化合物
WO2011143935A1 (zh) * 2010-05-21 2011-11-24 山东轩竹医药科技有限公司 碳青霉烯衍生物或其水合物的晶型及其制备方法与用途
CN102250095A (zh) * 2010-05-21 2011-11-23 山东轩竹医药科技有限公司 碳青霉烯衍生物或其水合物的晶型及其制备方法
CN102267996A (zh) * 2010-06-03 2011-12-07 山东轩竹医药科技有限公司 碳青霉烯类衍生物或其水合物的晶型及其制备方法
CN103025733B (zh) * 2010-06-03 2015-11-25 山东轩竹医药科技有限公司 碳青霉烯类衍生物或其水合物的晶型及其制备方法与用途
WO2012079289A1 (zh) * 2010-12-16 2012-06-21 珠海亿邦制药股份有限公司 碳青霉烯衍生物的无定形粉末和多晶型物及其制备方法和应用
CN102584827B (zh) * 2010-12-21 2015-08-12 山东轩竹医药科技有限公司 含氨基磺酰基杂环甲胺基甲酰基吡咯烷的碳青霉烯化合物
CN110698480B (zh) * 2018-07-09 2023-09-08 武汉启瑞药业有限公司 一种厄他培南中间体的合成及纯化方法
CN112174965B (zh) * 2019-07-03 2022-02-08 轩竹生物科技股份有限公司 氘修饰的碳青霉烯衍生物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
JPS6019787A (ja) * 1983-07-12 1985-01-31 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物及びその製造法
JPS60104088A (ja) * 1983-11-11 1985-06-08 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物およびその製造法
JPS6058987A (ja) * 1983-09-09 1985-04-05 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物およびその製造法
JPS6479181A (en) * 1983-11-11 1989-03-24 Sumitomo Pharma Novel beta-lactam compound and production thereof
US4925838A (en) 1988-03-18 1990-05-15 Fujisawa Pharmaceutical Company, Ltd. 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
NO178498C (no) * 1990-02-23 1996-04-10 Sankyo Co Analogifremgangsmåte ved fremstilling av terapeutisk aktive karbapenemderivater
JPH0341066A (ja) * 1990-07-04 1991-02-21 Sumitomo Pharmaceut Co Ltd ２―置換アミノカルボニル―４―メルカプトピロリジン誘導体
JP3384768B2 (ja) * 1995-12-21 2003-03-10 三共株式会社 １−メチルカルバペネム誘導体を含有する医薬
JP2000508343A (ja) * 1996-10-28 2000-07-04 メルク エンド カンパニー インコーポレーテッド 安定化されたカルバペネム抗生物質組成物及びその製造方法
TW445265B (en) * 1996-11-25 2001-07-11 Meiji Seika Kaisha Carbapenem derivatives and antimicrobial agents
CA2303446C (en) * 1997-09-13 2004-10-26 Korea Institute Of Science And Technology Carbapenem derivatives and a preparation method thereof
US8318716B2 (en) * 2009-12-31 2012-11-27 Kbp Biosciences Co., Ltd. Carbapenem derivatives

Also Published As

Publication number Publication date
EP2177522A1 (en) 2010-04-21
EP2177522A4 (en) 2012-01-25
JP5406181B2 (ja) 2014-02-05
CN101372489A (zh) 2009-02-25
CN101720326B (zh) 2012-07-18
US20100197653A1 (en) 2010-08-05
EP2177522B1 (en) 2013-09-04
CN101720326A (zh) 2010-06-02
WO2009000210A1 (fr) 2008-12-31
JP2010531310A (ja) 2010-09-24
CN101372489B (zh) 2011-05-18
US8293895B2 (en) 2012-10-23

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