HK1139332A1 - -羥基三苯氧胺的化學穩定組合物 - Google Patents

-羥基三苯氧胺的化學穩定組合物

Info

Publication number
HK1139332A1
HK1139332A1 HK10106178.9A HK10106178A HK1139332A1 HK 1139332 A1 HK1139332 A1 HK 1139332A1 HK 10106178 A HK10106178 A HK 10106178A HK 1139332 A1 HK1139332 A1 HK 1139332A1
Authority
HK
Hong Kong
Prior art keywords
chemically stable
stable compositions
hydroxy tamoxifen
tamoxifen
hydroxy
Prior art date
Application number
HK10106178.9A
Other languages
English (en)
Inventor
Dana C Hilt
Valrie Masini-Eteve
Richard Fedynec
Brigitte Taravella
Original Assignee
Besins Healthcare Lu Sarl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Besins Healthcare Lu Sarl filed Critical Besins Healthcare Lu Sarl
Publication of HK1139332A1 publication Critical patent/HK1139332A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
HK10106178.9A 2004-03-22 2010-06-23 -羥基三苯氧胺的化學穩定組合物 HK1139332A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04290762A EP1579857A1 (en) 2004-03-22 2004-03-22 Chemically stable compositions of 4-hydroxy tamoxifen
US10/805,530 US20050208139A1 (en) 2004-03-22 2004-03-22 Chemically stable compositions of 4-hydroxy tamoxifen

Publications (1)

Publication Number Publication Date
HK1139332A1 true HK1139332A1 (zh) 2010-09-17

Family

ID=34854723

Family Applications (2)

Application Number Title Priority Date Filing Date
HK07104159.2A HK1098674A1 (en) 2004-03-22 2007-04-20 Chemically stable compositions of 4-hydroxy tamoxifen
HK10106178.9A HK1139332A1 (zh) 2004-03-22 2010-06-23 -羥基三苯氧胺的化學穩定組合物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK07104159.2A HK1098674A1 (en) 2004-03-22 2007-04-20 Chemically stable compositions of 4-hydroxy tamoxifen

Country Status (22)

Country Link
US (1) US20050208139A1 (zh)
EP (4) EP1579857A1 (zh)
JP (1) JP5489407B2 (zh)
CN (1) CN101080222B (zh)
AR (1) AR048587A1 (zh)
AT (1) ATE453387T1 (zh)
AU (1) AU2005227073B2 (zh)
CA (1) CA2557806C (zh)
DE (1) DE602005018613D1 (zh)
DK (1) DK1727532T3 (zh)
ES (3) ES2517894T3 (zh)
HK (2) HK1098674A1 (zh)
IL (2) IL177778A (zh)
MX (1) MXPA06010928A (zh)
NO (1) NO337298B1 (zh)
NZ (1) NZ549664A (zh)
PL (1) PL1727532T3 (zh)
PT (1) PT1727532E (zh)
RU (1) RU2389483C2 (zh)
TW (1) TWI401078B (zh)
WO (1) WO2005092310A2 (zh)
ZA (1) ZA200607291B (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1572171B1 (en) * 2002-12-18 2009-04-22 Laboratoires Besins International Reduction of breast density with 4-hydroxy tamoxifen
JP4938237B2 (ja) * 2002-12-18 2012-05-23 ラボラトワール ブザン アンテルナスィヨナル ４−ヒドロキシタモキシフェンによる乳房痛の治療
EP1952810B1 (en) 2003-04-01 2014-01-08 Besins Healthcare Luxembourg SARL Treatment of breast cancer with 4-hydroxytamoxifen
WO2004110420A1 (en) 2003-06-09 2004-12-23 Ascend Therapeutics, Inc. Treatment and prevention of excessive scarring with 4-hydroxy tamoxifen
US7968532B2 (en) 2003-12-15 2011-06-28 Besins Healthcare Luxembourg Treatment of gynecomastia with 4-hydroxy tamoxifen
US7507769B2 (en) 2004-03-22 2009-03-24 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
EP1647271A1 (en) * 2004-10-14 2006-04-19 Laboratoires Besins International 4-Hydroxy tamoxifen gel formulations
EP1799201B1 (en) * 2004-10-14 2008-11-26 Laboratoires Besins International 4-hydroxy tamoxifen gel formulations
US8785501B2 (en) 2009-10-13 2014-07-22 Duquesne University Of The Holy Spirit Anti-cancer tamoxifen-melatonin hybrid ligand
US10016370B2 (en) * 2011-07-14 2018-07-10 Able Cerebral, Llc Composition, device and method for delayed and sustained release of brain energy molecules

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Publication number Priority date Publication date Assignee Title
FR2558373B1 (fr) * 1984-01-20 1987-07-03 Mauvais Jarvis Pierre Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee
US5475851A (en) * 1986-04-14 1995-12-12 National Instruments Corporation Method and apparatus for improved local and global variable capabilities in a graphical data flow program
US5002938A (en) * 1988-03-21 1991-03-26 Bristol-Myers Squibb Company Antifungal gel formulations
CA2032695A1 (en) 1989-12-20 1991-06-21 Hiroshi Akimoto Condensed heterocyclic compounds, their production and use
DE4407742C1 (de) * 1994-03-08 1995-06-22 Hexal Pharma Gmbh Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat
US5809266A (en) * 1994-07-29 1998-09-15 Oracle Corporation Method and apparatus for generating reports using declarative tools
DE4435784C2 (de) * 1994-10-06 1998-10-29 Heraeus Electro Nite Int Elektrisch beheizbarer Starterkat
US5777621A (en) * 1994-12-22 1998-07-07 Apple Computer, Inc. Quality control mechanism for three-dimensional graphics rendering
EP0883587A1 (en) * 1996-01-20 1998-12-16 Bradford University Tamoxifen and analogues thereof
ES2156361T5 (es) * 1996-03-29 2012-12-26 Keyvest Gmbh Cosmético o bien composición cosmética para el alisado y la tersura de la piel en el caso de tejido adiposo afectado, en especial en el caso de la "celulitis"
US6083996A (en) * 1997-11-05 2000-07-04 Nexmed Holdings, Inc. Topical compositions for NSAI drug delivery
WO1999033451A2 (en) * 1997-12-23 1999-07-08 Hexal Ag Mixture and pharmaceutical composition comprising z-4-hydroxytamoxifen and cyclodextrin
JP2000038335A (ja) * 1998-07-22 2000-02-08 Kanebo Ltd 皮膚化粧料
AU6890800A (en) 1999-08-23 2001-03-19 Eli Lilly And Company A novel crystalline form of disodium n-[4-[2-(2-amino-4,7-dihydro-4-oxo-3h-pyrrolo[2,3-D]- pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid salt and processes therefor
DE10033853A1 (de) * 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
US20040198706A1 (en) * 2003-03-11 2004-10-07 Carrara Dario Norberto R. Methods and formulations for transdermal or transmucosal application of active agents
US6503894B1 (en) * 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
AU2002340120A1 (en) * 2001-10-04 2003-04-14 Cellegy Pharmaceuticals, Inc. Semisolid topical hormonal compositions and methods for treatment
ES2330188T3 (es) * 2001-12-07 2009-12-07 Besins Manufacturing Belgium Composicion farmaceutica en forma de gel o de solucion a base de dihidrotestoterona, su procedimiento de preparacion y sus utilizaciones.
US6695171B2 (en) * 2002-02-12 2004-02-24 Seaquistperfect Dispensing Foreign, Inc. Pump dispenser
EP1572171B1 (en) * 2002-12-18 2009-04-22 Laboratoires Besins International Reduction of breast density with 4-hydroxy tamoxifen
JP4938237B2 (ja) * 2002-12-18 2012-05-23 ラボラトワール ブザン アンテルナスィヨナル ４−ヒドロキシタモキシフェンによる乳房痛の治療
EP1952810B1 (en) * 2003-04-01 2014-01-08 Besins Healthcare Luxembourg SARL Treatment of breast cancer with 4-hydroxytamoxifen
WO2004110420A1 (en) * 2003-06-09 2004-12-23 Ascend Therapeutics, Inc. Treatment and prevention of excessive scarring with 4-hydroxy tamoxifen
US7968532B2 (en) * 2003-12-15 2011-06-28 Besins Healthcare Luxembourg Treatment of gynecomastia with 4-hydroxy tamoxifen
DK1694319T3 (da) * 2003-12-15 2008-11-17 Besins Int Lab Anvendelser af 4-hydroxytamoxifen til fremstilling af et medikament til behandling af gynækomasti
US7507769B2 (en) * 2004-03-22 2009-03-24 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
EP1647271A1 (en) * 2004-10-14 2006-04-19 Laboratoires Besins International 4-Hydroxy tamoxifen gel formulations

Also Published As

Publication number Publication date
EP2269599B1 (en) 2013-02-20
IL215897A (en) 2014-09-30
TW200533334A (en) 2005-10-16
US20050208139A1 (en) 2005-09-22
PL1727532T3 (pl) 2010-06-30
RU2006137282A (ru) 2008-04-27
WO2005092310A3 (en) 2005-12-01
IL215897A0 (en) 2011-12-29
EP1727532B1 (en) 2009-12-30
CA2557806A1 (en) 2005-10-06
ES2517894T3 (es) 2014-11-04
EP2147670A1 (en) 2010-01-27
JP5489407B2 (ja) 2014-05-14
NZ549664A (en) 2011-01-28
ES2337069T3 (es) 2010-04-20
JP2007530498A (ja) 2007-11-01
AU2005227073A1 (en) 2005-10-06
RU2389483C2 (ru) 2010-05-20
NO337298B1 (no) 2016-03-07
EP2269599A1 (en) 2011-01-05
AU2005227073B2 (en) 2011-06-23
IL177778A (en) 2011-12-29
NO20064765L (no) 2006-10-20
HK1098674A1 (en) 2007-07-27
ZA200607291B (en) 2008-04-30
EP1579857A1 (en) 2005-09-28
PT1727532E (pt) 2010-03-30
CA2557806C (en) 2011-08-30
EP1727532A2 (en) 2006-12-06
DK1727532T3 (da) 2010-05-03
DE602005018613D1 (de) 2010-02-11
CN101080222A (zh) 2007-11-28
CN101080222B (zh) 2013-08-07
ATE453387T1 (de) 2010-01-15
WO2005092310A2 (en) 2005-10-06
ES2402921T3 (es) 2013-05-10
EP2147670B1 (en) 2014-10-01
TWI401078B (zh) 2013-07-11
MXPA06010928A (es) 2006-12-15
IL177778A0 (en) 2006-12-31
AR048587A1 (es) 2006-05-10

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