HK1129596A1 - Methods and compositions for treating disease - Google Patents

Methods and compositions for treating disease

Info

Publication number
HK1129596A1
HK1129596A1 HK09108675.6A HK09108675A HK1129596A1 HK 1129596 A1 HK1129596 A1 HK 1129596A1 HK 09108675 A HK09108675 A HK 09108675A HK 1129596 A1 HK1129596 A1 HK 1129596A1
Authority
HK
Hong Kong
Prior art keywords
compositions
methods
treating disease
disease
treating
Prior art date
Application number
HK09108675.6A
Other languages
English (en)
Chinese (zh)
Inventor
Thomas D Reed
Robert P Beech
Original Assignee
Intrexon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intrexon Corp filed Critical Intrexon Corp
Publication of HK1129596A1 publication Critical patent/HK1129596A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0093—Purging against cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/724—Glycosyltransferases (EC 2.4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/02—Pentosyltransferases (2.4.2)
    • C12Y204/02036—NAD(+)--diphthamide ADP-ribosyltransferase (2.4.2.36)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK09108675.6A 2006-07-26 2009-09-23 Methods and compositions for treating disease HK1129596A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82038106P 2006-07-26 2006-07-26
US88909507P 2007-02-09 2007-02-09
PCT/US2007/016747 WO2008073154A2 (en) 2006-07-26 2007-07-26 Methods and compositions for treating disease

Publications (1)

Publication Number Publication Date
HK1129596A1 true HK1129596A1 (en) 2009-12-04

Family

ID=39512236

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09108675.6A HK1129596A1 (en) 2006-07-26 2009-09-23 Methods and compositions for treating disease

Country Status (17)

Country Link
US (3) US20100003226A1 (xx)
EP (1) EP2043662B1 (xx)
JP (1) JP2009544711A (xx)
KR (1) KR20090035011A (xx)
AU (1) AU2007332980A1 (xx)
CA (1) CA2658836C (xx)
DK (1) DK2043662T3 (xx)
ES (1) ES2553332T3 (xx)
HK (1) HK1129596A1 (xx)
HU (1) HUE027142T2 (xx)
IL (1) IL196638A (xx)
MX (1) MX2009000966A (xx)
NZ (1) NZ575075A (xx)
PL (1) PL2043662T3 (xx)
PT (1) PT2043662E (xx)
RU (1) RU2468820C2 (xx)
WO (1) WO2008073154A2 (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013109944A1 (en) * 2012-01-18 2013-07-25 The Trustees Of The University Of Pennsylvania Methods for assessing risk for cancer using biomarkers
CN108498532B (zh) 2012-05-09 2021-07-23 坎泰克斯制药股份有限公司 骨髓抑制的治疗
US10052346B2 (en) 2015-02-17 2018-08-21 Cantex Pharmaceuticals, Inc. Treatment of myelodysplastic syndromes with 2-O and,or 3-O desulfated heparinoids
EP3258940A1 (en) * 2015-02-17 2017-12-27 Cantex Pharmaceuticals, Inc. Adoptive cell transfer methods
MX2018005886A (es) 2015-11-11 2018-08-15 Intrexon Corp Composiciones y metodos para la expresion de polipeptidos biologicamente activos a partir de un vector unico para tratamiento de condiciones cardiacas y otras patologias.
US20210128639A1 (en) * 2017-05-09 2021-05-06 Keio University Cell preparation for treating brain tumor

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830686A (en) * 1994-01-13 1998-11-03 Calydon Tissue-specific enhancer active in prostate
AU702323B2 (en) * 1994-03-15 1999-02-18 Selective Genetics, Inc. Heparin-binding growth factors for gene therapy and anterior eye disorders
CA2221269A1 (en) * 1995-05-16 1996-11-21 Lois A. Chandler Compositions containing nucleic acids and ligands for therapeutic treatment
EP0923387B1 (en) * 1996-06-24 2001-09-26 Selective Genetics, Inc. Heparin-coated medical devices for intravenous use containing heparin-binding growth factor conjugates
CN1303436A (zh) * 1998-02-19 2001-07-11 圣朱迪儿童研究医院 致敏和抑制人肿瘤细胞生长的组合物和方法
US7691370B2 (en) * 1998-10-15 2010-04-06 Canji, Inc. Selectivity replicating viral vector
WO2000075347A2 (en) * 1999-06-07 2000-12-14 Wolfgang Hillen Tet repressor-based transcriptional regulatory proteins
ATE338135T1 (de) 2000-03-22 2006-09-15 Rheogene Holdings Inc Induziertes genexpressionssystem basierend auf ecdysonrezeptoren
US20040033600A1 (en) 2001-03-21 2004-02-19 Palli Subba Reddy Ecdysone receptor-based inducible gene expression system
ES2394877T3 (es) * 2000-08-14 2013-02-06 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Recombinación homóloga mejorada mediada por proteínas de recombinación de lambda
US8105825B2 (en) 2000-10-03 2012-01-31 Intrexon Corporation Multiple inducible gene regulation system
AU2002248372B8 (en) * 2001-01-19 2008-03-20 Vegenics Limited FLT4(VEGFR-3) as a target for tumor imaging and anti-tumor therapy
MXPA03007493A (es) 2001-02-20 2004-10-15 Rheogene Holdings Inc Nuevo sistema de expresion genetica inducible a base de receptor de ecdisona/receptor x retinoide de invertebrado.
US8715959B2 (en) 2001-02-20 2014-05-06 Intrexon Corporation Substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
WO2002066615A2 (en) 2001-02-20 2002-08-29 Rheogene, Inc. Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
ES2392508T3 (es) 2001-02-20 2012-12-11 Intrexon Corporation Receptores X retinoides quiméricos y su uso en un sistema inducible de expresión génica basado en receptores de ecdisona novedoso
US6828102B2 (en) * 2001-11-20 2004-12-07 Albany Medical College Plasmids and methods for monitoring endonuclease digestion efficiency
EP1327688A1 (en) * 2002-01-14 2003-07-16 Vereniging Voor Christelijk Wetenschappelijk Onderwijs Adenoviruses with enhanced lytic potency
WO2004016791A1 (en) * 2002-08-01 2004-02-26 Evolva Ltd Methods of mixing large numbers of heterologous genes
US7785871B2 (en) 2002-10-09 2010-08-31 Intrexon Corporation DNA cloning vector plasmids and methods for their use
EP1631319A4 (en) * 2003-05-30 2007-10-31 Cleveland Clinic Foundation IN VIVO PRODUCTION OF A CLOSTRIDIUM NEUROTOXIN LIGHT CHAIN PEPTIDE
CA2436196A1 (en) * 2003-07-25 2005-01-25 Oncolytics Biotech Inc. Oncolytic virus for purging cellular compositions of cells of lymphoid malignancies
US7935510B2 (en) 2004-04-30 2011-05-03 Intrexon Corporation Mutant receptors and their use in a nuclear receptor-based inducible gene expression system
NZ583974A (en) 2004-05-18 2011-11-25 Intrexon Corp Methods for dynamic vector assembly of DNA cloning vector plasmids

Also Published As

Publication number Publication date
KR20090035011A (ko) 2009-04-08
PT2043662E (pt) 2015-11-25
HUE027142T2 (en) 2016-08-29
MX2009000966A (es) 2009-03-05
EP2043662A4 (en) 2010-04-14
EP2043662B1 (en) 2015-09-09
US20150132265A1 (en) 2015-05-14
US20100003226A1 (en) 2010-01-07
NZ575075A (en) 2011-10-28
IL196638A (en) 2013-11-28
CA2658836C (en) 2017-11-28
CA2658836A1 (en) 2008-06-19
IL196638A0 (en) 2009-11-18
WO2008073154A3 (en) 2008-12-04
JP2009544711A (ja) 2009-12-17
US20170191027A1 (en) 2017-07-06
EP2043662A2 (en) 2009-04-08
AU2007332980A1 (en) 2008-06-19
PL2043662T3 (pl) 2016-03-31
ES2553332T3 (es) 2015-12-07
RU2468820C2 (ru) 2012-12-10
DK2043662T3 (en) 2015-12-14
WO2008073154A2 (en) 2008-06-19
RU2009103208A (ru) 2010-09-10

Similar Documents

Publication Publication Date Title
IL291175A (en) Compositions and methods for treating collagen-mediated diseases
IL257681A (en) Methods and compositions for the treatment of cancer
PL2578081T4 (pl) Kompozycje, sposoby i urządzenia do leczenia chorób wątroby
HK1125868A1 (en) Compositions and methods for treating bone
EP1959929A4 (en) COMPOSITIONS AND METHODS FOR TREATING DERMATOLOGICAL SUFFERING
IL197721A0 (en) Compositions and methods for diagnosing and treating cancer
EP2032166A4 (en) COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CANCER
IL195619A0 (en) Compositions and methods for joininig non-conjoined iumens
IL198723A0 (en) Methods and compositions for therapeutic treatment
EP2069391A4 (en) COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING EYE DRYING
EP2056849A4 (en) METHODS AND COMPOSITIONS FOR TREATING IGE MEDIATED DISEASES
EP2057179A4 (en) COMPOSITION AND METHOD FOR THE TREATMENT OF MYELOSUPPRESSION
HK1129596A1 (en) Methods and compositions for treating disease
GB0718918D0 (en) Compositions and methods for treating skin conditions
EP2099491A4 (en) COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CANCER
GB0620695D0 (en) Composition and methods for the treatment of nurdegenerative disease
EP2094279A4 (en) METHOD AND COMPOSITIONS FOR THE TREATMENT OF INFLUENZA
GB0618309D0 (en) Compositions and methods for the treatment of disease
ZA201001779B (en) Compositions and methods for treating collagen-mediated diseases
EP2068629A4 (en) COMPOSITIONS AND METHODS FOR TREATING CANCER
GB0507963D0 (en) Composition and method for treating disease
GB0522732D0 (en) Composition and method for treating disease

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20200728