HK1128305A1 - Mutant type ii beta- lactam acylases - Google Patents

Mutant type ii beta- lactam acylases

Info

Publication number
HK1128305A1
HK1128305A1 HK09106042.6A HK09106042A HK1128305A1 HK 1128305 A1 HK1128305 A1 HK 1128305A1 HK 09106042 A HK09106042 A HK 09106042A HK 1128305 A1 HK1128305 A1 HK 1128305A1
Authority
HK
Hong Kong
Prior art keywords
beta
lactam
mutant type
lactam acylase
mutant
Prior art date
Application number
HK09106042.6A
Other languages
English (en)
Inventor
Van Der Jan Metske Laan
Richard Kerkman
Willem Bijleveld
Bianca Gielesen
Original Assignee
Dsm Sinochem Pharm Nl Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Sinochem Pharm Nl Bv filed Critical Dsm Sinochem Pharm Nl Bv
Publication of HK1128305A1 publication Critical patent/HK1128305A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK09106042.6A 2005-12-28 2009-07-06 Mutant type ii beta- lactam acylases HK1128305A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05113024 2005-12-28
PCT/EP2006/012654 WO2007073947A2 (en) 2005-12-28 2006-12-28 Mutant type ii beta- lactam acylases

Publications (1)

Publication Number Publication Date
HK1128305A1 true HK1128305A1 (en) 2009-10-23

Family

ID=36584602

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09106042.6A HK1128305A1 (en) 2005-12-28 2009-07-06 Mutant type ii beta- lactam acylases

Country Status (7)

Country Link
EP (2) EP2851423B1 (pt)
KR (1) KR20080084986A (pt)
CN (1) CN101351549B (pt)
BR (1) BRPI0621278A2 (pt)
ES (1) ES2571865T3 (pt)
HK (1) HK1128305A1 (pt)
WO (1) WO2007073947A2 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103060298B (zh) * 2012-12-31 2014-07-02 安徽丰原基因工程技术有限公司 一种头孢菌素c酰化酶突变体及其编码基因与应用
KR101985911B1 (ko) * 2017-12-28 2019-06-04 아미코젠주식회사 Achromobacter sp. CCM 4824 유래 페니실린 G 아실라제 변이체 및 이의 이용
CN109055475A (zh) * 2018-08-03 2018-12-21 菏泽睿智科技开发有限公司 一种粪产碱杆菌的新用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003894A (en) 1971-08-17 1977-01-18 Gist-Brocades N.V. Preparation of 7-substituted amino-desacetoxycephalosporanic acid compounds
PT97116B (pt) 1990-03-23 1998-10-30 Gist Brocades Nv Processo para modular a producao de metabolitos secundarios nomeadamente derivados de beta-lactama
EP0453048B1 (en) 1990-04-18 1998-06-17 Gist-Brocades N.V. Mutated beta-lactam acylase genes
US5318896A (en) 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
GB9204439D0 (en) * 1992-02-27 1992-04-15 Fujisawa Pharmaceutical Co A new cephalosporin c acylase
BR9407108A (pt) 1993-07-30 1996-08-27 Gist Brocades Nv Processo para a preparação e recuperação de ácido 7-amino desacetoxi cefalosporânico (7-adca) vetor de ADN recombinante e célula hospedeira transformada com um vetor definido
HU219265B (en) 1993-07-30 2001-03-28 Gist Brocades Bv Process for the efficient production of 7-adca via 3-(carboxyethylthio)propionyl-7-adca, recombinant dna vectors and host cells
TW400384B (en) 1993-11-01 2000-08-01 Fujisawa Pharmaceutical Co A new cephalosporin C acylase
GB9424945D0 (en) * 1994-12-09 1995-02-08 Fujisawa Pharmaceutical Co A new cephalosporin C acylase
CN1165616C (zh) 1995-07-18 2004-09-08 吉斯特·布罗卡迪斯股份有限公司 一种改进的固定化青霉素g酰基转移酶
WO1998048037A1 (en) 1997-04-22 1998-10-29 Dsm N.V. A METHOD FOR CONTROLLING THE SOLUBILITY OF A β-LACTAM NUCLEUS
ES2400562T3 (es) 2003-05-28 2013-04-10 Dsm Sinochem Pharmaceuticals Netherlands B.V. Compuesto de cefem
KR100530299B1 (ko) 2003-08-11 2005-11-22 산도즈 게엠베하 변이 세팔로스포린 ｃ 아실라제 및 이를 이용한 7-ａｃａ 제조방법
ITMI20040016A1 (it) 2004-01-12 2004-04-12 Antibiotics S P A Cefalosporina c acilasi

Also Published As

Publication number Publication date
EP1974029A2 (en) 2008-10-01
EP2851423B1 (en) 2016-03-02
CN101351549B (zh) 2013-03-20
ES2571865T3 (es) 2016-05-27
WO2007073947A3 (en) 2007-11-08
EP2851423A1 (en) 2015-03-25
KR20080084986A (ko) 2008-09-22
CN101351549A (zh) 2009-01-21
BRPI0621278A2 (pt) 2011-12-06
WO2007073947A2 (en) 2007-07-05

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20201228