HK1128305A1 - Mutant type ii beta- lactam acylases - Google Patents

Mutant type ii beta- lactam acylases

Info

Publication number
HK1128305A1
HK1128305A1 HK09106042.6A HK09106042A HK1128305A1 HK 1128305 A1 HK1128305 A1 HK 1128305A1 HK 09106042 A HK09106042 A HK 09106042A HK 1128305 A1 HK1128305 A1 HK 1128305A1
Authority
HK
Hong Kong
Prior art keywords
beta
lactam
mutant type
lactam acylase
mutant
Prior art date
Application number
HK09106042.6A
Other languages
English (en)
Inventor
Van Der Jan Metske Laan
Richard Kerkman
Willem Bijleveld
Bianca Gielesen
Original Assignee
Dsm Sinochem Pharm Nl Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Sinochem Pharm Nl Bv filed Critical Dsm Sinochem Pharm Nl Bv
Publication of HK1128305A1 publication Critical patent/HK1128305A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK09106042.6A 2005-12-28 2009-07-06 Mutant type ii beta- lactam acylases HK1128305A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05113024 2005-12-28
PCT/EP2006/012654 WO2007073947A2 (en) 2005-12-28 2006-12-28 Mutant type ii beta- lactam acylases

Publications (1)

Publication Number Publication Date
HK1128305A1 true HK1128305A1 (en) 2009-10-23

Family

ID=36584602

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09106042.6A HK1128305A1 (en) 2005-12-28 2009-07-06 Mutant type ii beta- lactam acylases

Country Status (7)

Country Link
EP (2) EP1974029A2 (xx)
KR (1) KR20080084986A (xx)
CN (1) CN101351549B (xx)
BR (1) BRPI0621278A2 (xx)
ES (1) ES2571865T3 (xx)
HK (1) HK1128305A1 (xx)
WO (1) WO2007073947A2 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103060298B (zh) * 2012-12-31 2014-07-02 安徽丰原基因工程技术有限公司 一种头孢菌素c酰化酶突变体及其编码基因与应用
KR101985911B1 (ko) * 2017-12-28 2019-06-04 아미코젠주식회사 Achromobacter sp. CCM 4824 유래 페니실린 G 아실라제 변이체 및 이의 이용
CN109055475A (zh) * 2018-08-03 2018-12-21 菏泽睿智科技开发有限公司 一种粪产碱杆菌的新用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003894A (en) 1971-08-17 1977-01-18 Gist-Brocades N.V. Preparation of 7-substituted amino-desacetoxycephalosporanic acid compounds
PT97116B (pt) 1990-03-23 1998-10-30 Gist Brocades Nv Processo para modular a producao de metabolitos secundarios nomeadamente derivados de beta-lactama
ES2119756T3 (es) 1990-04-18 1998-10-16 Gist Brocades Nv Genes de beta lactama acilasa mutados.
US5318896A (en) 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
GB9204439D0 (en) * 1992-02-27 1992-04-15 Fujisawa Pharmaceutical Co A new cephalosporin c acylase
SK282617B6 (sk) 1993-07-30 2002-10-08 Dsm N. V. Spôsob výroby a izolácie 7-aminodesacetoxycefalosporánovej kyseliny
PL180799B1 (pl) 1993-07-30 2001-04-30 Gist Brocades Bv Sposób wydajnego wytwarzania 7-ADCA poprzez 2-(karboksyetylotio)acetylo-7-ADCA i 3-(karboksymetylotio)-propionylo-7-ADCA
TW400384B (en) 1993-11-01 2000-08-01 Fujisawa Pharmaceutical Co A new cephalosporin C acylase
GB9424945D0 (en) * 1994-12-09 1995-02-08 Fujisawa Pharmaceutical Co A new cephalosporin C acylase
ES2318851T3 (es) 1995-07-18 2009-05-01 Dsm Ip Assets B.V. Penilicina g acilasa inmovilizada mejorada.
AU7648798A (en) 1997-04-22 1998-11-13 Gist-Brocades B.V. A method for controlling the solubility of a beta-lactam nucleus
JP2006528970A (ja) 2003-05-28 2006-12-28 デーエスエム アイピー アセッツ ベー. ヴェー. セフェム化合物
KR100530299B1 (ko) 2003-08-11 2005-11-22 산도즈 게엠베하 변이 세팔로스포린 c 아실라제 및 이를 이용한 7-aca 제조방법
ITMI20040016A1 (it) 2004-01-12 2004-04-12 Antibiotics S P A Cefalosporina c acilasi

Also Published As

Publication number Publication date
EP2851423B1 (en) 2016-03-02
ES2571865T3 (es) 2016-05-27
CN101351549A (zh) 2009-01-21
BRPI0621278A2 (pt) 2011-12-06
EP1974029A2 (en) 2008-10-01
EP2851423A1 (en) 2015-03-25
KR20080084986A (ko) 2008-09-22
WO2007073947A2 (en) 2007-07-05
CN101351549B (zh) 2013-03-20
WO2007073947A3 (en) 2007-11-08

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20201228