HK1125387A1 - Compositions and methods for fusion protein separation - Google Patents

Compositions and methods for fusion protein separation

Info

Publication number
HK1125387A1
HK1125387A1 HK09103410.7A HK09103410A HK1125387A1 HK 1125387 A1 HK1125387 A1 HK 1125387A1 HK 09103410 A HK09103410 A HK 09103410A HK 1125387 A1 HK1125387 A1 HK 1125387A1
Authority
HK
Hong Kong
Prior art keywords
compositions
methods
fusion protein
protein separation
cleavage site
Prior art date
Application number
HK09103410.7A
Other languages
English (en)
Inventor
Sujeong Kim
Jong-Mook Kim
Song Shan Xu
Original Assignee
Viromed Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viromed Co Ltd filed Critical Viromed Co Ltd
Publication of HK1125387A1 publication Critical patent/HK1125387A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5431—IL-11
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57581—Thymosin; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
HK09103410.7A 2005-04-20 2009-04-14 Compositions and methods for fusion protein separation HK1125387A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67287905P 2005-04-20 2005-04-20
PCT/IB2006/002378 WO2006126102A2 (fr) 2005-04-20 2006-04-20 Compositions et procedes de separation de proteines hybrides

Publications (1)

Publication Number Publication Date
HK1125387A1 true HK1125387A1 (en) 2009-08-07

Family

ID=37452418

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09103410.7A HK1125387A1 (en) 2005-04-20 2009-04-14 Compositions and methods for fusion protein separation

Country Status (9)

Country Link
US (2) US7585943B2 (fr)
EP (1) EP1871785B1 (fr)
JP (1) JP4897792B2 (fr)
KR (1) KR101312339B1 (fr)
CN (1) CN101287748B (fr)
AT (1) ATE466868T1 (fr)
DE (1) DE602006014126D1 (fr)
HK (1) HK1125387A1 (fr)
WO (1) WO2006126102A2 (fr)

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KR101541935B1 (ko) * 2007-09-26 2015-08-05 인트렉손 코포레이션 합성 5'ｕｔｒ, 발현 벡터, 및 전이유전자 발현의 증가방법
KR100980457B1 (ko) 2008-06-27 2010-09-07 한국생명공학연구원 대장균에서 활성형 인간 인터루킨-6의 생산 및 정제방법
CA2730721C (fr) * 2008-08-25 2016-08-09 Viromed Co., Ltd. Conjugues de biopolymere comprenant un analogue de l'interleukine-11
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CN102262158A (zh) * 2010-05-27 2011-11-30 戴国祯 重组融合蛋白质在快速诊断检测中的直接应用
WO2011151716A1 (fr) 2010-06-04 2011-12-08 Lupin Limited Procédé de purification d'il-11 humaine recombinante
WO2011151721A1 (fr) 2010-06-04 2011-12-08 Lupin Limited Procédé de production de protéines de fusion à l'aide de la thioredoxine tronquée d'e. coli
CA2807749C (fr) 2010-08-05 2023-02-28 Council Of Scientific & Industrial Research Proteines de fusion recombinants possedant des proprietes thrombolytiques et anticoagulantes
CN102161700A (zh) * 2011-01-19 2011-08-24 温州医学院 一种新型人白细胞介素-11
US8580922B2 (en) 2011-03-04 2013-11-12 Shire Human Genetic Therapies, Inc. Peptide linkers for polypeptide compositions and methods for using same
EP2680879B1 (fr) * 2011-03-04 2021-01-06 Shire Human Genetic Therapies, Inc. Lieurs peptidiques pour compositions de polypeptide et procédés pour les utiliser
KR20140036905A (ko) * 2012-09-18 2014-03-26 삼성전자주식회사 이중특이 항체를 포함하는 단백질 복합체
WO2014084432A1 (fr) * 2012-11-30 2014-06-05 경상대학교 산학협력단 Vecteurs d'expression d'helicobacter pylori
US20140364368A1 (en) * 2013-06-06 2014-12-11 Massachusetts Institute Of Technology Stimulus responsive nanocomplexes and methods of use thereof
CN105473610A (zh) * 2013-08-21 2016-04-06 卡迪拉保健有限公司 用于pth的纯化方法
KR101814048B1 (ko) 2014-01-28 2018-01-02 (주)에이피테크놀로지 대량 생산이 가능하도록 개선된 경구투여용 트롬보포이에틴 및 이의 대량 생산공정
ES2952405T3 (es) 2014-12-01 2023-10-31 Pfenex Inc Parejas de fusión para la producción de péptidos
CN104437411A (zh) * 2014-12-15 2015-03-25 武汉大学 可逆组装和分解的Strep-tag多肽标记的生物分子衍生化基质及其应用
CN106884030A (zh) * 2015-12-16 2017-06-23 丰益(上海)生物技术研发中心有限公司 提高含纤维素结合域的融合蛋白的发酵产量的方法
JP6758889B2 (ja) * 2016-04-07 2020-09-23 シスメックス株式会社 標的タンパク質の精製方法
WO2020113403A1 (fr) * 2018-12-04 2020-06-11 Beijing Percans Oncology Co. Ltd. Protéines de fusion de cytokines
KR102140531B1 (ko) * 2018-08-07 2020-08-04 (주)휴온스 Gly-Tβ4의 제조방법
CN114805598A (zh) * 2019-04-28 2022-07-29 广州市雷德生物科技有限公司 促进蛋白二聚体形成的拉链扣结构及其应用
CN110484551B (zh) * 2019-07-29 2021-04-02 因之彩生物科技（武汉）有限公司 金属硫蛋白表达载体及其应用
CN111909947B (zh) * 2020-08-04 2022-06-07 辽宁省海洋水产科学研究院 一种仿刺参β-胸腺素的制备及应用
CN112946041B (zh) * 2021-02-06 2022-07-22 自然资源部第一海洋研究所 一种基于融合蛋白传感器的重金属离子检测方法
CN115078728A (zh) * 2021-03-11 2022-09-20 盛禾(中国)生物制药有限公司 一种融合蛋白的快速分析方法
CN114644715A (zh) * 2022-03-04 2022-06-21 苏州红冠庄国药股份有限公司 一种igfbp-3和igf-1的融合蛋白及复合物制备方法

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Also Published As

Publication number Publication date
EP1871785A4 (fr) 2009-03-18
WO2006126102A8 (fr) 2008-05-15
DE602006014126D1 (de) 2010-06-17
US20100285526A1 (en) 2010-11-11
JP4897792B2 (ja) 2012-03-14
EP1871785A2 (fr) 2008-01-02
JP2008539696A (ja) 2008-11-20
US8106158B2 (en) 2012-01-31
KR20080002845A (ko) 2008-01-04
ATE466868T1 (de) 2010-05-15
CN101287748A (zh) 2008-10-15
CN101287748B (zh) 2013-03-27
US20080171852A9 (en) 2008-07-17
US20060276625A1 (en) 2006-12-07
US7585943B2 (en) 2009-09-08
EP1871785B1 (fr) 2010-05-05
KR101312339B1 (ko) 2013-09-27
WO2006126102A2 (fr) 2006-11-30

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