HK1121461A1 - Water-soluble benzoazepine compound and its pharmaceutical composition - Google Patents
Water-soluble benzoazepine compound and its pharmaceutical compositionInfo
- Publication number
- HK1121461A1 HK1121461A1 HK09101802.7A HK09101802A HK1121461A1 HK 1121461 A1 HK1121461 A1 HK 1121461A1 HK 09101802 A HK09101802 A HK 09101802A HK 1121461 A1 HK1121461 A1 HK 1121461A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- water
- benzoazepine compound
- soluble
- pharmaceutical composition
- benzoazepine
- Prior art date
Links
- -1 benzoazepine compound Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/5532—Seven-(or more) membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/5532—Seven-(or more) membered rings
- C07F9/5535—Seven-(or more) membered rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005375457 | 2005-12-27 | ||
| PCT/JP2006/326311 WO2007074915A1 (en) | 2005-12-27 | 2006-12-22 | Water-soluble benzoazepine compound and its pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1121461A1 true HK1121461A1 (en) | 2009-04-24 |
Family
ID=37877008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK09101802.7A HK1121461A1 (en) | 2005-12-27 | 2009-02-25 | Water-soluble benzoazepine compound and its pharmaceutical composition |
Country Status (23)
| Country | Link |
|---|---|
| US (6) | US20100004206A1 (ru) |
| EP (2) | EP1968990B1 (ru) |
| JP (2) | JP4644287B2 (ru) |
| KR (1) | KR101008931B1 (ru) |
| CN (1) | CN101346390B (ru) |
| AR (2) | AR058737A1 (ru) |
| AU (1) | AU2006330277B2 (ru) |
| BR (1) | BRPI0620715A2 (ru) |
| CA (1) | CA2633929A1 (ru) |
| CY (1) | CY1116208T1 (ru) |
| DK (1) | DK1968990T3 (ru) |
| ES (1) | ES2533007T3 (ru) |
| HK (1) | HK1121461A1 (ru) |
| IL (1) | IL191935A (ru) |
| MY (1) | MY146042A (ru) |
| NO (1) | NO342436B1 (ru) |
| PL (1) | PL1968990T3 (ru) |
| PT (1) | PT1968990E (ru) |
| RU (1) | RU2418804C2 (ru) |
| SI (1) | SI1968990T1 (ru) |
| TW (1) | TWI323257B (ru) |
| WO (1) | WO2007074915A1 (ru) |
| ZA (1) | ZA200805011B (ru) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5590780B2 (ja) * | 2007-06-26 | 2014-09-17 | 大塚製薬株式会社 | 医薬 |
| TWI459947B (zh) | 2007-06-26 | 2014-11-11 | Otsuka Pharma Co Ltd | 苯并氮呯化合物及藥學製劑 |
| AU2009257174A1 (en) * | 2008-06-09 | 2009-12-17 | Dimerix Bioscience Pty Ltd | Novel receptor hetero-dimers/-oligomers |
| CN102020609A (zh) * | 2009-09-17 | 2011-04-20 | 北京本草天源药物研究院 | 托伐普坦晶体或无定形物及其制备方法 |
| DE102010041263A1 (de) * | 2010-09-23 | 2012-03-29 | Siemens Medical Instruments Pte. Ltd. | Hörgerätegehäuse mit Dichtungslippe |
| TWI633887B (zh) | 2012-05-31 | 2018-09-01 | 大塚製藥股份有限公司 | 用於預防及／或治療多囊性腎臟病之藥物 |
| JP6265999B2 (ja) * | 2012-12-28 | 2018-01-24 | 大塚製薬株式会社 | 光学活性のトルバプタンを含む注射用持効性製剤及びその製造方法 |
| TW201605488A (zh) | 2013-10-15 | 2016-02-16 | 大塚製藥股份有限公司 | 用以預防及／或治療多囊腎病之藥物 |
| EP3481837B1 (en) * | 2016-07-07 | 2023-12-06 | Cyclerion Therapeutics, Inc. | Phosphorus prodrugs of sgc stimulators |
| JP2021014406A (ja) * | 2017-10-25 | 2021-02-12 | トーアエイヨー株式会社 | バソプレシン受容体拮抗剤 |
| CN113383001A (zh) * | 2019-01-30 | 2021-09-10 | 大塚制药株式会社 | 生产苯并氮杂卓化合物的方法 |
| JP7130879B2 (ja) * | 2019-03-28 | 2022-09-05 | 大塚製薬株式会社 | ベンゾアゼピン化合物含有医薬組成物 |
| WO2020196814A1 (en) | 2019-03-28 | 2020-10-01 | Otsuka Pharmaceutical Co., Ltd. | Benzoazepine compound-containing freeze-dried composition |
| CA3207957A1 (en) | 2021-02-10 | 2022-08-18 | Shanghai Senhui Medicine Co., Ltd. | Benzazepine compounds, preparation method therefor and pharmaceutical use thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5043273A (en) | 1989-08-17 | 1991-08-27 | Monsanto Company | Phosphorylated glycosidase inhibitor prodrugs |
| US5258510A (en) | 1989-10-20 | 1993-11-02 | Otsuka Pharma Co Ltd | Benzoheterocyclic compounds |
| US5753677A (en) * | 1989-10-20 | 1998-05-19 | Otsuka Pharmaceutical Co., Ltd. | Benzoheterocyclic compounds |
| TW198715B (ru) | 1991-04-19 | 1993-01-21 | Dtsuka Seiyaku Kk | |
| US5466683A (en) * | 1994-08-25 | 1995-11-14 | Teva Pharmaceutical Industries Ltd. | Water-soluble analogs of carbamazepine |
| GB9602080D0 (en) | 1996-02-02 | 1996-04-03 | Pfizer Ltd | Pharmaceutical compounds |
| JP4210355B2 (ja) | 1997-07-03 | 2009-01-14 | 大塚製薬株式会社 | 固形製剤組成物 |
| US5972882A (en) * | 1997-12-15 | 1999-10-26 | University Of Kansas Medical Center | Treatment of polycystic kidney disease using vasopressin V2 receptor antagonists |
| US6436989B1 (en) * | 1997-12-24 | 2002-08-20 | Vertex Pharmaceuticals, Incorporated | Prodrugs of aspartyl protease inhibitors |
| TWI322689B (en) | 2003-02-24 | 2010-04-01 | Otsuka Pharma Co Ltd | Method for treating severe heart failure and medicament therefor |
-
2006
- 2006-12-22 PL PL06843686T patent/PL1968990T3/pl unknown
- 2006-12-22 US US12/159,027 patent/US20100004206A1/en not_active Abandoned
- 2006-12-22 MY MYPI20082112A patent/MY146042A/en unknown
- 2006-12-22 EP EP06843686.4A patent/EP1968990B1/en not_active Not-in-force
- 2006-12-22 KR KR1020087018000A patent/KR101008931B1/ko active IP Right Grant
- 2006-12-22 JP JP2008530267A patent/JP4644287B2/ja active Active
- 2006-12-22 PT PT68436864T patent/PT1968990E/pt unknown
- 2006-12-22 AU AU2006330277A patent/AU2006330277B2/en not_active Ceased
- 2006-12-22 DK DK06843686T patent/DK1968990T3/da active
- 2006-12-22 BR BRPI0620715-4A patent/BRPI0620715A2/pt not_active Application Discontinuation
- 2006-12-22 EP EP13183898.9A patent/EP2674436A1/en not_active Withdrawn
- 2006-12-22 RU RU2008130887/04A patent/RU2418804C2/ru active
- 2006-12-22 CA CA002633929A patent/CA2633929A1/en not_active Abandoned
- 2006-12-22 ZA ZA200805011A patent/ZA200805011B/xx unknown
- 2006-12-22 CN CN2006800494221A patent/CN101346390B/zh active Active
- 2006-12-22 ES ES06843686.4T patent/ES2533007T3/es active Active
- 2006-12-22 SI SI200631915T patent/SI1968990T1/sl unknown
- 2006-12-22 WO PCT/JP2006/326311 patent/WO2007074915A1/en active Application Filing
- 2006-12-25 TW TW095148734A patent/TWI323257B/zh not_active IP Right Cessation
- 2006-12-26 AR ARP060105779A patent/AR058737A1/es not_active Application Discontinuation
-
2008
- 2008-06-04 IL IL191935A patent/IL191935A/en not_active IP Right Cessation
- 2008-06-05 NO NO20082630A patent/NO342436B1/no not_active IP Right Cessation
-
2009
- 2009-02-25 HK HK09101802.7A patent/HK1121461A1/xx not_active IP Right Cessation
-
2010
- 2010-10-22 JP JP2010237235A patent/JP5550522B2/ja not_active Expired - Fee Related
- 2010-12-13 US US12/966,629 patent/US20110082110A1/en not_active Abandoned
- 2010-12-28 US US12/980,266 patent/US20110098250A1/en not_active Abandoned
-
2012
- 2012-05-01 US US13/461,642 patent/US9809609B2/en not_active Expired - Fee Related
- 2012-05-01 US US13/461,665 patent/US20120277189A1/en not_active Abandoned
-
2013
- 2013-08-12 US US13/964,853 patent/US9303052B2/en not_active Expired - Fee Related
-
2015
- 2015-04-27 CY CY20151100385T patent/CY1116208T1/el unknown
-
2016
- 2016-12-26 AR ARP160104016A patent/AR107193A2/es unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20181222 |