HK1121461A1 - Water-soluble benzoazepine compound and its pharmaceutical composition - Google Patents

Water-soluble benzoazepine compound and its pharmaceutical composition

Info

Publication number
HK1121461A1
HK1121461A1 HK09101802.7A HK09101802A HK1121461A1 HK 1121461 A1 HK1121461 A1 HK 1121461A1 HK 09101802 A HK09101802 A HK 09101802A HK 1121461 A1 HK1121461 A1 HK 1121461A1
Authority
HK
Hong Kong
Prior art keywords
water
benzoazepine compound
soluble
pharmaceutical composition
benzoazepine
Prior art date
Application number
HK09101802.7A
Other languages
English (en)
Inventor
Makoto Komatsu
Fumitaka Goto
Yasuhiro Menjo
Keigo Yamada
Takakuni Matsuda
Yusuke Kato
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37877008&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1121461(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of HK1121461A1 publication Critical patent/HK1121461A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532—Seven-(or more) membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532—Seven-(or more) membered rings
    • C07F9/5535—Seven-(or more) membered rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
HK09101802.7A 2005-12-27 2009-02-25 Water-soluble benzoazepine compound and its pharmaceutical composition HK1121461A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005375457 2005-12-27
PCT/JP2006/326311 WO2007074915A1 (en) 2005-12-27 2006-12-22 Water-soluble benzoazepine compound and its pharmaceutical composition

Publications (1)

Publication Number Publication Date
HK1121461A1 true HK1121461A1 (en) 2009-04-24

Family

ID=37877008

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09101802.7A HK1121461A1 (en) 2005-12-27 2009-02-25 Water-soluble benzoazepine compound and its pharmaceutical composition

Country Status (23)

Country Link
US (6) US20100004206A1 (pt)
EP (2) EP2674436A1 (pt)
JP (2) JP4644287B2 (pt)
KR (1) KR101008931B1 (pt)
CN (1) CN101346390B (pt)
AR (2) AR058737A1 (pt)
AU (1) AU2006330277B2 (pt)
BR (1) BRPI0620715A2 (pt)
CA (1) CA2633929A1 (pt)
CY (1) CY1116208T1 (pt)
DK (1) DK1968990T3 (pt)
ES (1) ES2533007T3 (pt)
HK (1) HK1121461A1 (pt)
IL (1) IL191935A (pt)
MY (1) MY146042A (pt)
NO (1) NO342436B1 (pt)
PL (1) PL1968990T3 (pt)
PT (1) PT1968990E (pt)
RU (1) RU2418804C2 (pt)
SI (1) SI1968990T1 (pt)
TW (1) TWI323257B (pt)
WO (1) WO2007074915A1 (pt)
ZA (1) ZA200805011B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI459947B (zh) 2007-06-26 2014-11-11 Otsuka Pharma Co Ltd 苯并氮呯化合物及藥學製劑
JP5590780B2 (ja) * 2007-06-26 2014-09-17 大塚製薬株式会社 医薬
AU2009257174A1 (en) * 2008-06-09 2009-12-17 Dimerix Bioscience Pty Ltd Novel receptor hetero-dimers/-oligomers
CN102020609A (zh) * 2009-09-17 2011-04-20 北京本草天源药物研究院 托伐普坦晶体或无定形物及其制备方法
DE102010041263A1 (de) * 2010-09-23 2012-03-29 Siemens Medical Instruments Pte. Ltd. Hörgerätegehäuse mit Dichtungslippe
TWI704919B (zh) * 2012-05-31 2020-09-21 日商大塚製藥股份有限公司 用於預防及/或治療多囊性腎臟病之藥物
NZ630346A (en) * 2012-12-28 2016-06-24 Otsuka Pharma Co Ltd Injectable depot formulation comprising optically active tolvaptan and process of producing the same
TW201605488A (zh) 2013-10-15 2016-02-16 大塚製藥股份有限公司 用以預防及／或治療多囊腎病之藥物
CA3029374A1 (en) * 2016-07-07 2018-01-11 Ironwood Pharmaceuticals, Inc. Phosphorus prodrugs of sgc stimulators
JP2021014406A (ja) * 2017-10-25 2021-02-12 トーアエイヨー株式会社 バソプレシン受容体拮抗剤
EA202192088A1 (ru) * 2019-01-30 2021-11-03 Оцука Фармасьютикал Ко., Лтд. Способ получения бензоазепинового соединения
EA202192635A1 (ru) * 2019-03-28 2021-12-10 Оцука Фармасьютикал Ко., Лтд. Фармацевтическая композиция, содержащая бензоазепиновое соединение
EP3946259A1 (en) 2019-03-28 2022-02-09 Otsuka Pharmaceutical Co., Ltd. Benzoazepine compound-containing freeze-dried composition
CN116744935A (zh) 2021-02-10 2023-09-12 上海森辉医药有限公司 苯并氮杂䓬类化合物及其制备方法和医药用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5043273A (en) 1989-08-17 1991-08-27 Monsanto Company Phosphorylated glycosidase inhibitor prodrugs
US5258510A (en) 1989-10-20 1993-11-02 Otsuka Pharma Co Ltd Benzoheterocyclic compounds
US5753677A (en) * 1989-10-20 1998-05-19 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds
CA2066104C (en) 1991-04-19 2003-05-27 Hidenori Ogawa Benzazepine derivatives as vasopressin antagonists
US5466683A (en) * 1994-08-25 1995-11-14 Teva Pharmaceutical Industries Ltd. Water-soluble analogs of carbamazepine
GB9602080D0 (en) 1996-02-02 1996-04-03 Pfizer Ltd Pharmaceutical compounds
JP4210355B2 (ja) 1997-07-03 2009-01-14 大塚製薬株式会社 固形製剤組成物
US5972882A (en) * 1997-12-15 1999-10-26 University Of Kansas Medical Center Treatment of polycystic kidney disease using vasopressin V2 receptor antagonists
US6436989B1 (en) * 1997-12-24 2002-08-20 Vertex Pharmaceuticals, Incorporated Prodrugs of aspartyl protease inhibitors
TWI322689B (en) 2003-02-24 2010-04-01 Otsuka Pharma Co Ltd Method for treating severe heart failure and medicament therefor

Also Published As

Publication number Publication date
CY1116208T1 (el) 2017-02-08
NO342436B1 (no) 2018-05-22
US20120277188A1 (en) 2012-11-01
NO20082630L (no) 2008-09-16
BRPI0620715A2 (pt) 2011-11-22
SI1968990T1 (sl) 2015-05-29
US9809609B2 (en) 2017-11-07
JP5550522B2 (ja) 2014-07-16
IL191935A (en) 2013-07-31
US9303052B2 (en) 2016-04-05
EP1968990A1 (en) 2008-09-17
TWI323257B (en) 2010-04-11
AR107193A2 (es) 2018-03-28
CA2633929A1 (en) 2007-07-05
US20110098250A1 (en) 2011-04-28
JP4644287B2 (ja) 2011-03-02
RU2418804C2 (ru) 2011-05-20
AU2006330277A1 (en) 2007-07-05
PT1968990E (pt) 2015-03-16
CN101346390B (zh) 2011-11-09
AR058737A1 (es) 2008-02-20
US20100004206A1 (en) 2010-01-07
EP2674436A1 (en) 2013-12-18
US20120277189A1 (en) 2012-11-01
DK1968990T3 (da) 2015-04-27
KR20080078916A (ko) 2008-08-28
ES2533007T3 (es) 2015-04-06
RU2008130887A (ru) 2010-02-10
MY146042A (en) 2012-06-15
PL1968990T3 (pl) 2015-06-30
US20110082110A1 (en) 2011-04-07
WO2007074915A8 (en) 2007-11-08
TW200734309A (en) 2007-09-16
JP2011046731A (ja) 2011-03-10
IL191935A0 (en) 2008-12-29
JP2009521397A (ja) 2009-06-04
KR101008931B1 (ko) 2011-01-17
CN101346390A (zh) 2009-01-14
ZA200805011B (en) 2009-11-25
WO2007074915A1 (en) 2007-07-05
EP1968990B1 (en) 2015-02-11
US20130331358A1 (en) 2013-12-12
AU2006330277B2 (en) 2011-10-06

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20181222