HK1118721A1 - Use of l-carnitine or of alkanoyl l-carnitines for the preparation of a physiological supplement or medicament for ophthalmic use in the form of eye-drops l- l- - Google Patents

Use of l-carnitine or of alkanoyl l-carnitines for the preparation of a physiological supplement or medicament for ophthalmic use in the form of eye-drops l- l-

Info

Publication number
HK1118721A1
HK1118721A1 HK08110830.5A HK08110830A HK1118721A1 HK 1118721 A1 HK1118721 A1 HK 1118721A1 HK 08110830 A HK08110830 A HK 08110830A HK 1118721 A1 HK1118721 A1 HK 1118721A1
Authority
HK
Hong Kong
Prior art keywords
carnitines
carnitine
alkanoyl
medicament
drops
Prior art date
Application number
HK08110830.5A
Other languages
English (en)
Chinese (zh)
Inventor
Aleardo Koverech
Nicola Pescosolido
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of HK1118721A1 publication Critical patent/HK1118721A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
HK08110830.5A 2005-07-01 2008-09-29 Use of l-carnitine or of alkanoyl l-carnitines for the preparation of a physiological supplement or medicament for ophthalmic use in the form of eye-drops l- l- HK1118721A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05014337 2005-07-01
PCT/EP2006/062919 WO2007003481A1 (en) 2005-07-01 2006-06-06 Use of l-carnitine or of alkanoyl l-carnitines for the preparation of a physiological supplement or medicament for ophthalmic use in the form of eye-drops

Publications (1)

Publication Number Publication Date
HK1118721A1 true HK1118721A1 (en) 2009-02-20

Family

ID=36930661

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08110830.5A HK1118721A1 (en) 2005-07-01 2008-09-29 Use of l-carnitine or of alkanoyl l-carnitines for the preparation of a physiological supplement or medicament for ophthalmic use in the form of eye-drops l- l-

Country Status (12)

Country Link
US (2) US7655698B2 (xx)
EP (1) EP1906949B1 (xx)
JP (1) JP5117384B2 (xx)
KR (1) KR101401353B1 (xx)
CN (1) CN101242825B (xx)
AU (1) AU2006265248B2 (xx)
BR (1) BRPI0612596A2 (xx)
CA (1) CA2611909C (xx)
HK (1) HK1118721A1 (xx)
MX (1) MX2007016047A (xx)
TW (1) TWI404526B (xx)
WO (1) WO2007003481A1 (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0612596A2 (pt) * 2005-07-01 2010-11-23 Sigma Tau Ind Farmaceuti uso de l-carnitina ou alcanoil-l-carnitinas para a preparação de um suplemento ou medicamento fisiológico para uso oftálmico na forma de gotas oftálmicas
CN101534812B (zh) * 2006-12-11 2012-09-05 希格马托制药工业公司 L-卡尼汀制备用于治疗角膜疾病的滴眼剂形式药物的用途
EP2101725A1 (en) * 2006-12-14 2009-09-23 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Use of l-carnitine or of alkanoyl l-carnitines for the preparation of a physiological supplement or medicament for ophthalmic use in the form of eye drops
WO2008077712A1 (en) * 2006-12-22 2008-07-03 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Gel useful for the delivery of ophthalmic drugs
WO2009006130A2 (en) * 2007-06-28 2009-01-08 Bausch & Lomb Incorporated Salt free hyaluronate ophthalmic solution
TWI474817B (zh) * 2008-07-04 2015-03-01 Sigma Tau Ind Farmaceuti 用於預防或治療調節性眼疲勞之化合物類
WO2010085568A1 (en) * 2009-01-21 2010-07-29 The Research Foundation Of State University Of New York Methods of diagnosing and treating severe dry eye syndrome
US20110015154A1 (en) * 2009-07-20 2011-01-20 Kellermann Gottfried H Supporting acetylcholine function
US20110098265A1 (en) * 2009-10-28 2011-04-28 Neuroscience, Inc. Methods for reducing cravings and impulses associated with addictive and compulsive behaviors
EP2363126A1 (en) * 2010-03-04 2011-09-07 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Composition comprising as active ingredient L-carnitine in combination with hydroxykynurenine-O-beta-DL-glucoside, for the prevention and/or treatment of pathologies of the eye due to ultraviolet radiation
US10085960B2 (en) 2012-03-30 2018-10-02 Brien Holden Vision Institute Methods and compositions for reducing ocular discomfort
US10238673B2 (en) * 2013-03-13 2019-03-26 Genetic Disease Investigators, LLC Methods and compositions for treatment of dry eye and correction of organ dysfunctions
EP2783695A1 (en) * 2013-03-28 2014-10-01 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Physiological supplement or medicament for ophthalmic use containing L-carnitine or alkanoyl L-carnitines in combination with eledoisin
US9173915B1 (en) 2014-10-10 2015-11-03 Peter F. Kador Antioxidant eye drops
CN110559261A (zh) * 2018-06-06 2019-12-13 常州药物研究所有限公司 含有纳米交联透明质酸的脂质体微乳及其制备方法和应用
CN110604812B (zh) * 2018-06-14 2023-01-31 陕西慧康生物科技有限责任公司 一种含有重组人溶菌酶的人工泪液
CN110604811B (zh) * 2018-06-14 2023-01-31 陕西慧康生物科技有限责任公司 含有重组人溶菌酶和重组人表皮生长因子的人工泪液
US20230346735A1 (en) * 2020-04-28 2023-11-02 Lonza Greenwood Llc Nutritional Composition Comprising Carnitine and Method for Treating or Preventing an Infection in a Mammal
WO2023069036A1 (en) * 2021-10-18 2023-04-27 Vsy Biyoteknoloji Ve Ilac Sanayi Anonim Sirketi An ophthalmic formulation for treatment and prevention of cataract and production method thereof

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1263606A (en) * 1985-05-29 1989-12-05 Jeffrey P. Gilbard Non-toxic opthalmic preparations
GB8710780D0 (en) * 1987-05-07 1987-06-10 Scras Opthalmological application of eicosapentaenoic acid
IT1235153B (it) * 1988-11-15 1992-06-22 Sigma Tau Ind Farmaceuti Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento
EP0546728A3 (en) * 1991-12-13 1993-09-08 Alcon Laboratories Inc Physiological tear compositions and methods for their preparation
WO1995005803A1 (en) * 1993-08-20 1995-03-02 Alcon Laboratories, Inc. Topical ophthalmic pharmaceutical vehicles
CN1160346A (zh) * 1994-09-14 1997-09-24 大正制药株式会社 用于修复角膜损伤的滴眼液
JPH08133968A (ja) * 1994-09-14 1996-05-28 Taisho Pharmaceut Co Ltd 角膜障害修復用点眼液
EP0861088A1 (en) * 1995-11-14 1998-09-02 Xoma Corporation Bactericidal permeability increasing protein (bpi) for treating conditions associated with corneal injury
KR980008239A (ko) * 1996-07-26 1998-04-30 김충환 사이클로스포린-함유 약학적 조성물
US5817630A (en) * 1997-03-18 1998-10-06 Austin Nutriceutical Corporation Glutathione antioxidant eye drops
AU1295200A (en) * 1998-11-13 2000-06-05 Continental Projects Limited Complexes of hyaluronic acid/carnitines and pharmaceutical and cosmetic compositions
US6720001B2 (en) * 1999-10-18 2004-04-13 Lipocine, Inc. Emulsion compositions for polyfunctional active ingredients
DK1142566T3 (da) * 2000-04-07 2004-02-09 Medidom Lab Oftalmologiske formuleringer på basis af ciclosporin, hyaluronsyre og polysorbat
RU2165749C1 (ru) * 2000-07-06 2001-04-27 Общество с ограниченной ответственностью "Научно-экспериментальное производство Микрохирургия глаза" Способ восстановления эндотелия роговицы
AU2002252338B2 (en) * 2001-03-15 2007-09-13 Rhode Island Hospital, A Lifespan Partner Taurine compounds
AU2003259145A1 (en) * 2002-07-17 2004-02-02 Spencer P. Thornton Treatment for dry eye syndrome
US7465463B2 (en) * 2002-09-04 2008-12-16 Polyheal, Ltd. Compositions comprising microspheres with anti-inflammatory properties for healing of ocular tissues
WO2004084877A1 (ja) * 2003-03-26 2004-10-07 Menicon Co., Ltd. 眼科用組成物
US8569367B2 (en) * 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
BRPI0612596A2 (pt) 2005-07-01 2010-11-23 Sigma Tau Ind Farmaceuti uso de l-carnitina ou alcanoil-l-carnitinas para a preparação de um suplemento ou medicamento fisiológico para uso oftálmico na forma de gotas oftálmicas

Also Published As

Publication number Publication date
KR20080030077A (ko) 2008-04-03
MX2007016047A (es) 2008-03-10
BRPI0612596A2 (pt) 2010-11-23
US20100093858A1 (en) 2010-04-15
EP1906949A1 (en) 2008-04-09
CN101242825A (zh) 2008-08-13
AU2006265248B2 (en) 2011-12-15
TWI404526B (zh) 2013-08-11
JP2009500369A (ja) 2009-01-08
US7655698B2 (en) 2010-02-02
KR101401353B1 (ko) 2014-05-29
US20070265338A1 (en) 2007-11-15
US8377988B2 (en) 2013-02-19
JP5117384B2 (ja) 2013-01-16
AU2006265248A1 (en) 2007-01-11
EP1906949B1 (en) 2015-02-11
TW200744574A (en) 2007-12-16
CN101242825B (zh) 2011-03-30
WO2007003481A1 (en) 2007-01-11
CA2611909C (en) 2014-01-07
CA2611909A1 (en) 2007-01-11

Similar Documents

Publication Publication Date Title
HK1118721A1 (en) Use of l-carnitine or of alkanoyl l-carnitines for the preparation of a physiological supplement or medicament for ophthalmic use in the form of eye-drops l- l-
USD647282S1 (en) Pajamas with detachable feet
USD638591S1 (en) Bone shape absorbent pad
IL183929A0 (en) Use of inerferon - ?? in the preparation of a medicament
GB2428974B (en) Further medical use of a botanical drug or dietary supplement
IL186555A (en) (4r, 9as) –5– Hydroxy – 4 – methyl – 6,10 – dioxo –10.9 a, 9,6,4,3 – hexahydro – 2 h – 1– oxa –8 a, 4a 4,2-diplooro-benzylamide carboxylic acid or its pharmacy salt, a preparation containing it and its use in the treatment or prevention of HIV
EP1758595A4 (en) Use of lipid conjugates in the treatment of diseases
IL187220A (en) Use of sodium arsenite sodium in the preparation of a drug for the treatment of metastatic tumor diseases
ZA200802897B (en) New pyrimidine derivatives and their use in therapy as well as the use of pyrimidine derivatives in the manufacture of a medicament for prevention and/or treatment of Alzheimer's Disease
IL195626A (en) Use of an ophthalmic device containing at least one prescription drug in combination with any carrier suitable for the provision of an eye for the preparation of a drug or an ophthalmic drug for the treatment of the disease in the back of the eye in a person or animal
IL186544A (en) Use of Acid 3,1 - Propandysulfonic or Sodium Salt in the Preparation of Pharmaceuticals for the Treatment of aa Amyloidosis and Pharmaceuticals for the Treatment of aa Amyloidosis
TWI366457B (en) Use of a beta2-adrenoceptor agonist for the preparation of a dermatological medicament
WO2007016679A3 (en) Combination immediate release controlled release levodopa and carbidopa dosage forms
HRP20130319T1 (hr) Upotreba kombinacije koju äśine l-karnitin ili alkanoil-l-karnitin, benzokinon topljiv u lipidima i omega-3-polinezasiä†ena masna kiselina, u pripravi dodatka za prehranu ili medikamenta za lijeäśenje bolesti rožnice
EP2094281A4 (en) USE OF LIPID CONJUGATES IN THE TREATMENT OF DISEASES OR OCULAR DISORDERS
GB0427856D0 (en) Maniflod for use in medicament dispenser
HUP0700370A2 (en) Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania
ZA201007391B (en) Use of dronedarone or a pharmaceutically acceptable salt thereof, for the preparation of a medicament for regulating the potassium in the blood
SI2918286T1 (sl) Farmacevtski pripravek, ki vsebuje inzulin v kristalni obliki in tudi v obliki raztopine
USD668972S1 (en) Milk bottle expiration timer
IL212215A0 (en) Use of lipid conjugates in the treatment of disease
HK1135019A1 (en) Use of l-carnitine for the preparation of a medicament in the form of eye- drops for treating corneal diseases l-
SI1714647T1 (sl) Uporaba agomelatina pri izdelavi zdravila za zdravljenje bipolarnih motenj
PL378537A1 (pl) Zastosowanie propionylo L-karnityny do otrzymywania leku do leczenia glaukomii
IL200192A (en) Use of l-cannitin and / or alkonial l-carnitine, or their common pharmaceutical salt, in combination with statin, for the preparation of a drug for the treatment of type 2 diabetes

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20190606