HK1114516A1 - Substituted sulfoxide compounds, methods for preparing the same and use thereof - Google Patents

Substituted sulfoxide compounds, methods for preparing the same and use thereof

Info

Publication number
HK1114516A1
HK1114516A1 HK08104408.0A HK08104408A HK1114516A1 HK 1114516 A1 HK1114516 A1 HK 1114516A1 HK 08104408 A HK08104408 A HK 08104408A HK 1114516 A1 HK1114516 A1 HK 1114516A1
Authority
HK
Hong Kong
Prior art keywords
preparing
methods
same
sulfoxide compounds
substituted sulfoxide
Prior art date
Application number
HK08104408.0A
Other languages
English (en)
Inventor
Jingen Deng
Qin Yang
Yongle Chen
Jin Zhu
Qiwei Wang
Qiuya Huang
Xuemei Hou
Original Assignee
Livzon Pharmaceutical Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Livzon Pharmaceutical Group filed Critical Livzon Pharmaceutical Group
Publication of HK1114516A1 publication Critical patent/HK1114516A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK08104408.0A 2005-03-25 2008-04-22 Substituted sulfoxide compounds, methods for preparing the same and use thereof HK1114516A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN200510058962 2005-03-25
PCT/CN2006/000490 WO2006099810A1 (en) 2005-03-25 2006-03-24 Substituted sulfoxide compounds, methods for preparing the same and use thereof

Publications (1)

Publication Number Publication Date
HK1114516A1 true HK1114516A1 (en) 2008-10-31

Family

ID=37023375

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08104408.0A HK1114516A1 (en) 2005-03-25 2008-04-22 Substituted sulfoxide compounds, methods for preparing the same and use thereof

Country Status (9)

Country Link
US (2) US20060217423A1 (ja)
EP (1) EP1861391B1 (ja)
JP (1) JP4837722B2 (ja)
AT (1) ATE528301T1 (ja)
AU (1) AU2006227032B2 (ja)
CA (1) CA2597632C (ja)
ES (1) ES2375298T3 (ja)
HK (1) HK1114516A1 (ja)
WO (1) WO2006099810A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2597632C (en) * 2005-03-25 2012-05-15 Livzon Pharmaceutical Group Inc. Substituted sulfoxide compounds, methods for preparing the same and use thereof
WO2008083319A1 (en) * 2006-12-29 2008-07-10 Il Yang Pharmaceutical Company, Ltd. Solid state forms of enantiopure ilaprazole
RU2466129C2 (ru) 2006-12-29 2012-11-10 Ил Янг Фармасьютикал Компани, Лтд. Твердые формы рацемического илапразола
WO2009061529A1 (en) * 2007-11-06 2009-05-14 Tap Pharmaceutical Products, Inc. (+)-enantiomer of 5-pyrrolyl-2-pyridylmethylsulfinyl benzimidazole and processing method eor preparing the same
KR101044880B1 (ko) * 2008-06-12 2011-06-28 일양약품주식회사 항궤양제 화합물의 합성에 유용한 중간체의 제조방법
CZ302548B6 (cs) * 2008-10-22 2011-07-07 Zentiva, A.S. Zpusob výroby 5-amino-2-[(4-methoxy-3-methyl-2-pyridyl)methylthio]-1H-benzimidazolu a 5-(1H-pyrrol-1-yl)-2-[(4-methoxy-3-methyl-2-pyridyl)methylthio]-1H-benzimidazolu
WO2011042910A2 (en) 2009-10-09 2011-04-14 Hetero Research Foundation Optical resolution of substituted 2-(2- pyridinylmethylsulphinyl)-1h-benzimidazoles
CN102336788B (zh) * 2011-06-29 2014-08-27 涂家生 质子泵抑制剂氨基葡萄糖复盐
US11666562B2 (en) 2020-04-02 2023-06-06 Northwestern University Ilaprazole for inhibiting the release of enveloped viruses from cells
WO2021217187A1 (en) * 2020-04-23 2021-10-28 Northwestern University Small molecule inhibitors that block the budding of enveloped viruses

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4035455A1 (de) 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
SE9301830D0 (sv) 1993-05-28 1993-05-28 Ab Astra New compounds
US5877192A (en) 1993-05-28 1999-03-02 Astra Aktiebolag Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole
KR0179401B1 (ko) * 1994-02-28 1999-03-20 송택선 신규한 5-피롤릴-2-피리딜메틸설피닐벤즈이미다졸 유도체
SE504459C2 (sv) * 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
KR20010065950A (ko) * 1999-12-30 2001-07-11 우재영 신규한 5-피롤릴-2-피리딜메틸설피닐 벤즈이미다졸유도체의 이성질체
AU2002332178B2 (en) * 2001-09-18 2005-12-08 Zeria Pharmaceutical Co., Ltd. Benzimidazole derivatives
WO2003089408A2 (en) * 2002-04-22 2003-10-30 Sun Pharmaceutical Industries Limited Optically active substituted pyridinylmethyl-sulphinyl-benzimidazole and salts
US6894066B2 (en) * 2002-05-09 2005-05-17 Bernard Charles Sherman Magnesium salt of S-omeprazole
CA2520157A1 (fr) * 2003-03-28 2004-10-14 Sidem Pharma Procede de preparation enantioselective de derives de sulfoxydes
CA2597632C (en) * 2005-03-25 2012-05-15 Livzon Pharmaceutical Group Inc. Substituted sulfoxide compounds, methods for preparing the same and use thereof

Also Published As

Publication number Publication date
US8017784B2 (en) 2011-09-13
EP1861391A4 (en) 2008-11-05
EP1861391A1 (en) 2007-12-05
EP1861391B1 (en) 2011-10-12
AU2006227032A1 (en) 2006-09-28
CA2597632A1 (en) 2006-09-28
US20060217423A1 (en) 2006-09-28
ES2375298T3 (es) 2012-02-28
JP2008534446A (ja) 2008-08-28
WO2006099810A1 (en) 2006-09-28
JP4837722B2 (ja) 2011-12-14
CA2597632C (en) 2012-05-15
AU2006227032B2 (en) 2010-02-25
US20080234487A1 (en) 2008-09-25
ATE528301T1 (de) 2011-10-15

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