HK1110784A1 - Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases - Google Patents

Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases

Info

Publication number
HK1110784A1
HK1110784A1 HK08105212.3A HK08105212A HK1110784A1 HK 1110784 A1 HK1110784 A1 HK 1110784A1 HK 08105212 A HK08105212 A HK 08105212A HK 1110784 A1 HK1110784 A1 HK 1110784A1
Authority
HK
Hong Kong
Prior art keywords
neoangiogenesis
revascularization
useful
pharmaceutical composition
ischemic heart
Prior art date
Application number
HK08105212.3A
Other languages
English (en)
Inventor
Ming Li
Lei Cheng
Hongwei Liu
Original Assignee
Lead Billion Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IB2005/003202 external-priority patent/WO2007049089A1/en
Priority claimed from PCT/IB2005/003191 external-priority patent/WO2007049088A1/en
Application filed by Lead Billion Ltd filed Critical Lead Billion Ltd
Publication of HK1110784A1 publication Critical patent/HK1110784A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/32—Unsaturated compounds containing hydroxy or O-metal groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Vascular Medicine (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
HK08105212.3A 2005-10-27 2008-05-08 Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases HK1110784A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/IB2005/003202 WO2007049089A1 (en) 2005-10-27 2005-10-27 Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues
PCT/IB2005/003191 WO2007049088A1 (en) 2005-10-27 2005-10-27 Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues
US79146206P 2006-04-13 2006-04-13
PCT/CN2006/002886 WO2007048353A1 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases

Publications (1)

Publication Number Publication Date
HK1110784A1 true HK1110784A1 (en) 2008-07-25

Family

ID=37967417

Family Applications (2)

Application Number Title Priority Date Filing Date
HK08105212.3A HK1110784A1 (en) 2005-10-27 2008-05-08 Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases
HK08108022.7A HK1112848A1 (en) 2005-10-27 2008-07-21 Pharmaceutical composition for regenerating myofibers in the treatment of muscle injuries

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK08108022.7A HK1112848A1 (en) 2005-10-27 2008-07-21 Pharmaceutical composition for regenerating myofibers in the treatment of muscle injuries

Country Status (10)

Country Link
US (6) US9155744B2 (es)
EP (2) EP1848445B1 (es)
JP (2) JP4950996B2 (es)
CN (1) CN101137387B (es)
AU (2) AU2006308337B2 (es)
CA (2) CA2593161C (es)
DK (2) DK1848440T3 (es)
ES (2) ES2427354T3 (es)
HK (2) HK1110784A1 (es)
WO (2) WO2007048353A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1848445B1 (en) 2005-10-27 2015-04-01 Lead Billion Limited Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases
JP5689117B2 (ja) * 2009-06-12 2015-03-25 ジェネレックス ファーマシューティカルズ インコーポレイテッド 心不全を防止及び治療するための組成物及び方法
EP2655390B1 (en) * 2010-12-23 2019-03-27 Huya Bioscience International LLC Purified cardiogenin isomer and related methods
WO2012107202A1 (en) * 2011-02-08 2012-08-16 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Sweetener, sweetener compositions, methods of making the same and consumables containing the same
ES2688879T3 (es) * 2012-05-16 2018-11-07 Prairie Berry Europe Gmbh Ácidos triterpénicos pentacíclicos polihidroxilados como inhibidores de la HMG-CoA reductasa
JP6024880B2 (ja) * 2012-09-03 2016-11-16 国立大学法人東北大学 環状デプシペプチドの新規使用方法
LU101117B1 (en) 2019-02-07 2020-08-07 Luxembourg Institute Of Science And Tech (List) METHOD FOR PRODUCING A COMPOSITION COMPRISING A 3-O-p-COUMAROYL ESTER OF TORMENTIC ACID FROM A PLANT CELL CULTURE, APPLICATIONS THEREOF AS ANTIPARASITIC AGENT FOR THE TREATMENT OF TRYPANOSOMIASIS
WO2023129377A1 (en) * 2022-01-03 2023-07-06 The Johns Hopkins University Methods and materials for treating heart attack
KR102645399B1 (ko) * 2022-07-25 2024-03-11 코스맥스엔에스 주식회사 유스카픽 에시드를 포함하는 근 기능 개선 또는 근육 질환 예방, 개선 또는 치료용 조성물

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62129220A (ja) * 1985-11-30 1987-06-11 Riide Chem Kk 制癌剤
JPS646289A (en) * 1987-06-29 1989-01-10 Lead Chem Co Ltd Pharmaceutical composition for remedy and crisis-prevention of acquired immunodeficiency syndrome
JPH0881489A (ja) * 1994-07-15 1996-03-26 Sagami Chem Res Center ポリガラクツロナーゼ阻害剤
US5916919A (en) 1997-06-27 1999-06-29 Dalhousie University Retrovirus protease inhibitors
JP2001335503A (ja) * 2000-05-29 2001-12-04 Teika Seiyaku Kk ラジカル消去用医薬品
JP4982665B2 (ja) * 2001-11-21 2012-07-25 リード ビリオン リミテッド ダイコンソウ（ＧｅｕｍＪａｐｏｎｉｃｕｍｔｈｕｎｂｖａｒ．）の有機抽出物を含む組成物およびその使用
CA2506762C (en) 2002-12-10 2011-11-08 The Chinese University Of Hong Kong An organic extract of geum japonicum thumb variant and use thereof
US20070053839A1 (en) * 2003-06-12 2007-03-08 Jianyi Zhang Directing cells to target tissues organs
CN1325055C (zh) 2003-10-24 2007-07-11 中山大学 甜叶甙r1及其衍生物在制备防治帕金森病的药物中的应用
CN1582946B (zh) 2004-06-09 2010-04-28 北京苏里曼医药科技有限公司 积雪草酸衍生物在制备防治心、脑血管疾病的药物中的用途
CN100467025C (zh) 2004-06-09 2009-03-11 北京苏里曼医药科技有限公司 积雪草总苷、积雪草苷或羟基积雪草苷在制备防治心、脑血管疾病药物中的用途
CN100531740C (zh) 2004-06-10 2009-08-26 北京苏里曼医药科技有限公司 一种辅助防治心、脑血管疾病的保健品
WO2007049088A1 (en) 2005-10-27 2007-05-03 Lead Billion Limited Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues
EP1848445B1 (en) 2005-10-27 2015-04-01 Lead Billion Limited Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases
WO2007049089A1 (en) 2005-10-27 2007-05-03 Lead Billion Limited Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues

Also Published As

Publication number Publication date
EP1848445A1 (en) 2007-10-31
CA2593171A1 (en) 2007-05-03
EP1848440B1 (en) 2013-07-17
EP1848440A1 (en) 2007-10-31
WO2007048353B1 (en) 2007-06-07
WO2007048353A1 (en) 2007-05-03
CN101137387B (zh) 2011-05-25
JP2009520683A (ja) 2009-05-28
AU2006308338B2 (en) 2009-11-05
US20090028959A1 (en) 2009-01-29
JP5117386B2 (ja) 2013-01-16
AU2006308337A1 (en) 2007-05-03
EP1848445A4 (en) 2010-07-21
CA2593171C (en) 2012-05-08
AU2006308338A1 (en) 2007-05-03
CA2593161A1 (en) 2007-05-03
CN101137387A (zh) 2008-03-05
US20190358251A1 (en) 2019-11-28
US20170189432A1 (en) 2017-07-06
US9155744B2 (en) 2015-10-13
US20080124388A1 (en) 2008-05-29
HK1112848A1 (en) 2008-09-19
ES2427354T3 (es) 2013-10-30
EP1848440A4 (en) 2010-07-21
DK1848440T3 (da) 2013-09-23
DK1848445T3 (en) 2015-05-26
US20220152070A1 (en) 2022-05-19
JP4950996B2 (ja) 2012-06-13
WO2007048352B1 (en) 2007-06-14
WO2007048352A1 (en) 2007-05-03
JP2009520684A (ja) 2009-05-28
ES2540912T3 (es) 2015-07-14
US20160058797A1 (en) 2016-03-03
CA2593161C (en) 2011-09-13
AU2006308337B2 (en) 2010-01-21
EP1848445B1 (en) 2015-04-01

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