HK1108582A1 - Methods for preparing purified lipopeptides - Google Patents

Methods for preparing purified lipopeptides

Info

Publication number
HK1108582A1
HK1108582A1 HK07113829.3A HK07113829A HK1108582A1 HK 1108582 A1 HK1108582 A1 HK 1108582A1 HK 07113829 A HK07113829 A HK 07113829A HK 1108582 A1 HK1108582 A1 HK 1108582A1
Authority
HK
Hong Kong
Prior art keywords
methods
lipopeptides
relates
present
preparing purified
Prior art date
Application number
HK07113829.3A
Other languages
English (en)
Inventor
Dennis Keith
Jan-Ji Lai
C Govardhan
N Khalaf
Original Assignee
Cubist Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27500563&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1108582(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cubist Pharm Inc filed Critical Cubist Pharm Inc
Publication of HK1108582A1 publication Critical patent/HK1108582A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
HK07113829.3A 2000-12-18 2007-12-19 Methods for preparing purified lipopeptides HK1108582A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25626800P 2000-12-18 2000-12-18
US27474101P 2001-03-09 2001-03-09
US34052501P 2001-12-13 2001-12-13
US34131501P 2001-12-13 2001-12-13

Publications (1)

Publication Number Publication Date
HK1108582A1 true HK1108582A1 (en) 2008-05-09

Family

ID=27500563

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07113829.3A HK1108582A1 (en) 2000-12-18 2007-12-19 Methods for preparing purified lipopeptides

Country Status (13)

Country Link
US (2) US20030045678A1 (he)
EP (3) EP1908770B2 (he)
JP (2) JP2004525108A (he)
KR (4) KR20110127732A (he)
CN (3) CN1592753A (he)
AT (1) ATE535539T1 (he)
AU (3) AU2002246687C1 (he)
CA (1) CA2432096A1 (he)
ES (2) ES2691680T3 (he)
HK (1) HK1108582A1 (he)
IL (3) IL156394A0 (he)
NZ (2) NZ571597A (he)
WO (1) WO2002056829A2 (he)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
US20090149453A1 (en) * 2002-05-23 2009-06-11 Activbiotics Pharma Llc Methods and compositions for treating bacterial infections and diseases associated therewith
US20040077533A1 (en) * 2002-05-23 2004-04-22 Sayada Chalom B. Methods and compositions for treating bacterial infections and diseases associated therewith
US20030236265A1 (en) * 2002-05-23 2003-12-25 Sayada Chalom B. Methods of treating bacterial infections and diseases associated therewith
WO2003103699A1 (en) 2002-06-06 2003-12-18 Vicuron Pharmaceuticals Inc. Use of ramoplanin to treat diseases associated with the use of antibiotics
US20040176404A1 (en) * 2002-12-12 2004-09-09 Sayada Chalom B. Methods and reagents for treating or preventing atherosclerosis and diseases associated therewith
US20040126414A1 (en) * 2002-12-12 2004-07-01 Michaelis Arthur F. Methods and compositions for treating and preventing ear infections
US7267624B2 (en) * 2004-07-30 2007-09-11 Acushnet Company Golf ball dimple pattern
US20080050441A1 (en) * 2006-07-20 2008-02-28 Enrico Bettetini Process for the preparation of solid sterile active pharmaceutical ingredient
WO2009144739A1 (en) * 2008-05-26 2009-12-03 Biocon Limited Amorphous daptomycin and a method of purification thereof
PT2398817E (pt) 2009-02-19 2015-08-28 Xellia Pharmaceuticals Aps Processo para purificar lipopéptidos
CN101830970B (zh) * 2009-03-12 2012-06-27 成都雅途生物技术有限公司 一种高纯度达托霉素(Daptomycin)的纯化制备方法
CN101899094B (zh) * 2009-06-01 2012-11-21 安徽丰原发酵技术工程研究有限公司 一种高纯达托霉素的制备方法
RU2607526C2 (ru) * 2009-11-23 2017-01-10 Кьюбист Фармасьютикалз ЭлЭлСи Липопептидные композиции и родственные способы
JP2013511522A (ja) * 2009-11-23 2013-04-04 イーグル・ファーマシューティカルズ・インコーポレーテッド ダプトマイシン製剤
KR101151878B1 (ko) * 2010-06-08 2012-05-31 미원상사주식회사 지방산 트리펩타이드염 및 이를 함유하는 항균 조성물
CN102276696B (zh) * 2010-06-09 2014-11-05 上海来益生物药物研究开发中心有限责任公司 达托霉素的纯化方法
ES2645769T3 (es) 2011-01-05 2017-12-07 Hospira, Inc. Secado por pulverización de la vancomicina
KR101034663B1 (ko) * 2011-03-18 2011-05-17 김태욱 손목 피로를 저감시키는 마우스
CN102206694B (zh) * 2011-04-06 2013-10-16 山东新时代药业有限公司 一种含有癸酸的缓释组合物
MX2013013760A (es) * 2011-05-26 2014-01-08 Cubist Pharm Inc Composiciones de cb-183, 315 y metodos relacionados.
CN102241732B (zh) * 2011-05-30 2015-01-21 浙江海正药业股份有限公司 一种脂肽化合物的纯化方法
KR20140057414A (ko) 2011-06-22 2014-05-12 바이옴 바이오사이언스 피브이티. 엘티디. 컨쥬게이트계 항진균 및 항세균 프로드러그
CN102875652A (zh) * 2011-07-13 2013-01-16 北大方正集团有限公司 一种分离纯化达托霉素的方法
WO2013012101A1 (ko) * 2011-07-15 2013-01-24 미원상사주식회사 지방산 트리펩타이드염 및 이를 함유하는 항균 조성물
CN102718839B (zh) * 2012-07-05 2017-05-24 鲁南新时代生物技术有限公司 一种分离纯化达托霉素的方法
US20150246024A1 (en) * 2012-08-20 2015-09-03 The University Of Chicago Methods and compositions for inhibiting gram positive bacteria
CN104043104B (zh) 2013-03-15 2018-07-10 浙江创新生物有限公司 含盐酸万古霉素的喷雾干粉及其工业化制备方法
CN104387444B (zh) * 2014-11-13 2017-12-08 北大医药重庆大新药业股份有限公司 一种达托霉素杂质rs‑2高纯度样品的制备方法
US11667674B2 (en) 2016-04-08 2023-06-06 Versitech Limited Antibacterial cyclic lipopeptides
US10647746B2 (en) 2016-04-08 2020-05-12 Versitech Limited Antibacterial cyclic lipopeptides
WO2017173932A1 (en) * 2016-04-08 2017-10-12 Versitech Limited Antibacterial cyclic lipopeptides
IT201600127655A1 (it) 2016-12-16 2018-06-16 Gnosis Spa Processo per la purificazione di antibiotici lipopolipeptidici
US10072045B1 (en) 2017-06-26 2018-09-11 Ramapo Pharmaceuticals, Inc. Antibacterial lipopeptides and methods for their preparation and use
IT201800006314A1 (it) * 2018-06-14 2019-12-14 Uso di resine a scambio cationico per la purificazione di antibiotici lipopolipeptidici
WO2020086931A1 (en) * 2018-10-25 2020-04-30 Cidara Therapeutics, Inc. Polymorph of echinocandin antifungal agent
CN113301885A (zh) 2018-12-21 2021-08-24 艾瑞克有限公司 新型组合物
CN112979756B (zh) * 2019-12-13 2023-01-03 浙江昌海制药有限公司 达托霉素的提纯方法
CN113480623B (zh) * 2021-08-09 2022-12-27 广州天赐高新材料股份有限公司 一种脂肽组合物及其制备方法和应用
CN116726145A (zh) * 2022-03-04 2023-09-12 海南普利制药股份有限公司 一种稳定的酯肽类药物组合物
WO2024085235A1 (ja) * 2022-10-20 2024-04-25 中外製薬株式会社 環状ペプチドの結晶の製造方法

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1021538B (de) † 1954-06-04 1957-12-27 Bristol Lab Inc Verfahren zur Herstellung und Gewinnung einer antibiotisch wirkenden Verbindung
US3854480A (en) 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
USRE32455E (en) 1978-10-16 1987-07-07 Eli Lilly And Company A-21978 antibiotics and process for their production
USRE31396E (en) * 1978-10-16 1983-09-27 Eli Lilly And Company A-21978 Antibiotics and process for their production
USRE32333E (en) 1978-10-16 1987-01-20 Eli Lilly And Company A-21978 Antibiotics and process for their production
EP0014815A3 (de) * 1978-12-20 1980-10-29 Ciba-Geigy Ag Peptidderivate, Verfahren zu deren Herstellung und Zwischenprodukte sowie pharmazeutische Präparate mit einer dieser Verbindungen
US4485045A (en) * 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
CA1195983A (en) 1982-02-27 1985-10-29 Graham Walker Antibacterial 1-normon-2-yl thiazoles and - oxazoles
USRE32310E (en) * 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4524135A (en) * 1982-05-21 1985-06-18 Eli Lilly And Company A-21978C cyclic peptides
USRE32311E (en) * 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4537717A (en) * 1982-05-21 1985-08-27 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4482487A (en) 1982-05-21 1984-11-13 Eli Lilly And Company A-21978C cyclic peptides
US4522811A (en) * 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
FR2533209B1 (fr) * 1982-09-22 1985-11-08 Centre Nat Rech Scient Lipopeptides, leur obtention et leur application comme emulsifiants
US4452775A (en) 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
US4544545A (en) * 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US4885243A (en) 1984-10-09 1989-12-05 Eli Lilly And Company Process for producing A-21978C derivatives
US4800157A (en) 1985-09-09 1989-01-24 Eli Lilly And Company Process for producing the A-21978C antibiotics
US4874843A (en) * 1987-12-03 1989-10-17 Eli Lilly And Company Chromatographic purification process
EP0294990A3 (en) † 1987-06-10 1990-05-09 Eli Lilly And Company Chromatographic purification process
ZA883887B (en) * 1987-06-10 1990-02-28 Lilly Co Eli Chromatographic purification process
US4994270A (en) * 1988-04-11 1991-02-19 Eli Lilly And Company A54145 antibiotics and process for their production
CA1337758C (en) * 1988-04-11 1995-12-19 Eli Lilly And Company Peptide antibiotics
US5039789A (en) * 1988-04-11 1991-08-13 Eli Lilly And Company A54145 cyclic peptides
US4886243A (en) * 1988-10-26 1989-12-12 Trumbull Christopher J Hydraulic jack ramp
EP0386951A3 (en) * 1989-03-06 1992-05-20 Eli Lilly And Company An improved diluent formulation for daptomycin
US5202309A (en) 1989-06-30 1993-04-13 Merck & Co., Inc. Antibiotic cyclopeptide fermentation product
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
JPH04167172A (ja) 1990-10-31 1992-06-15 Nec Corp ベクトルプロセッサ
JPH04224197A (ja) * 1990-12-26 1992-08-13 Fujitsu Ltd 生体高分子結晶化方法および装置
US5369093A (en) * 1991-03-15 1994-11-29 Merck & Co., Inc. Lipopeptide derivatives
US5336756A (en) † 1991-05-01 1994-08-09 Merck & Co., Inc. Process for crystalline cyclic lipopeptides
TW213468B (he) * 1991-06-29 1993-09-21 Hoechst Ag
US5393528A (en) * 1992-05-07 1995-02-28 Staab; Robert J. Dissolvable device for contraception or delivery of medication
DE69332954D1 (de) * 1992-10-21 2003-06-12 Gynetech Lab Inc Abgabesystem bestehend aus einem vaginaschwamm
EP0712405A1 (en) 1993-08-13 1996-05-22 Smithkline Beecham Plc Derivatives of monic acids a and c having antibacterial, antimycoplasmatical, antifungal and herbicidal activity
DE4411025A1 (de) 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
US5716960A (en) * 1995-01-13 1998-02-10 U.S. Bioscience Inc. And Individuals Crystalline trimetrexate salts and the process for making the same
JP3067972B2 (ja) * 1995-03-03 2000-07-24 新日本理化株式会社 ジアセタールの六方晶結晶、該六方晶結晶を含む核剤、該六方晶結晶を含むポリオレフィン系樹脂組成物及び成形物、並びに該組成物の成形方法
WO1997003959A1 (en) * 1995-07-17 1997-02-06 Warner-Lambert Company Crystalline [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid hemi calcium salt (atorvastatin)
DE19546573A1 (de) * 1995-12-13 1997-06-19 Uetikon Chemie Gmbh Kristallines Polymorph von Terazosin-Hydrochlorid, sowie Verfahren zu seiner Herstellung
US5972331A (en) * 1995-12-22 1999-10-26 Schering Corporation Crystalline interferon alpha for pulmonary delivery and method for producing the same
JP4711471B2 (ja) * 1996-07-05 2011-06-29 三菱商事フードテック株式会社 結晶マルチトール及びそれを含有する含蜜結晶の製造方法
US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
US5928666A (en) * 1996-11-12 1999-07-27 Cygnus Inc. Crystalline form of estradiol and pharmaceutical formulations comprising same
JP3569422B2 (ja) * 1996-12-26 2004-09-22 シャープ株式会社 結晶型オキソチタニルフタロシアニン及びそれを用いた電子写真感光体並びに画像形成方法
US6017562A (en) * 1997-04-28 2000-01-25 Arch Chemicals, Inc. Non-spherical and non-platelet crystalline forms of pyrithione salts
US5965747A (en) * 1997-07-10 1999-10-12 Merck & Co., Inc. Crystalline forms of antibiotic side chain intermediates
EP1059976A4 (en) * 1998-02-18 2001-02-28 Biospace Internat Inc DYNAMICALLY CONTROLLED CRYSTALIZATION METHOD, DEVICE AND CRYSTALS GENERATED THEREFOR
DE19807972A1 (de) † 1998-02-25 1999-08-26 Hoechst Marion Roussel De Gmbh Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung
EP1100947A4 (en) 1998-08-07 2001-09-05 Merck & Co Inc PRODUCTION OF AN ANTIBIOTIC
WO2000018419A2 (en) 1998-09-25 2000-04-06 Cubist Pharmaceuticals, Inc. Methods for administration of antibiotics
IL150223A0 (en) 1999-12-15 2002-12-01 Cubist Pharm Inc Lipopeptides and pharmaceutical compositions containing the same
BR0017028A (pt) 1999-12-15 2003-01-07 Cubist Pharm Inc Lipopepìdeos como agentes antibacterianos
WO2001044274A1 (en) 1999-12-15 2001-06-21 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
WO2002059145A1 (en) † 2000-12-18 2002-08-01 Cubist Pharmaceuticals, Inc. Methods for preparing purified lipopeptides
US9394340B2 (en) † 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides

Also Published As

Publication number Publication date
JP4927003B2 (ja) 2012-05-09
EP2261237A3 (en) 2011-01-26
CN102070703B (zh) 2014-08-06
JP2004525108A (ja) 2004-08-19
AU2002246688A1 (en) 2002-07-30
NZ554405A (en) 2009-04-30
EP2261237A2 (en) 2010-12-15
IL230244A (he) 2017-12-31
CN1982330B (zh) 2012-01-25
KR20090122469A (ko) 2009-11-30
EP1908770B2 (en) 2015-07-15
EP1908770A1 (en) 2008-04-09
ES2377931T3 (es) 2012-04-03
US20030045678A1 (en) 2003-03-06
CA2432096A1 (en) 2002-08-01
ES2377931T5 (es) 2015-11-04
KR20110127732A (ko) 2011-11-25
NZ571597A (en) 2010-05-28
EP2261237B1 (en) 2018-08-22
EP1343811A4 (en) 2004-12-08
AU2002246687C1 (en) 2009-11-05
AU2002246687B8 (en) 2008-10-02
AU2008207496A1 (en) 2008-09-11
CN102070703A (zh) 2011-05-25
CN1592753A (zh) 2005-03-09
AU2002246687B2 (en) 2008-05-29
WO2002056829A3 (en) 2003-03-27
EP1343811A1 (en) 2003-09-17
IL156394A (he) 2015-05-31
US20030045484A1 (en) 2003-03-06
AU2008207496B2 (en) 2012-06-14
IL156394A0 (en) 2004-01-04
JP2008214348A (ja) 2008-09-18
ES2691680T3 (es) 2018-11-28
EP1908770B1 (en) 2011-11-30
ATE535539T1 (de) 2011-12-15
CN1982330A (zh) 2007-06-20
KR20030081353A (ko) 2003-10-17
KR20080036661A (ko) 2008-04-28
WO2002056829A2 (en) 2002-07-25

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20191213