HK1104236A1 - Use of [d-meala]3-[etval]4-cyclosporin for the treatment of hepatitis c infection and pharmaceutical composition comprising said [d-meala]3- [etval]4-cyclosporin [d-meala]3-[etval]4 - Google Patents

Use of [d-meala]3-[etval]4-cyclosporin for the treatment of hepatitis c infection and pharmaceutical composition comprising said [d-meala]3- [etval]4-cyclosporin [d-meala]3-[etval]4

Info

Publication number
HK1104236A1
HK1104236A1 HK07112681.2A HK07112681A HK1104236A1 HK 1104236 A1 HK1104236 A1 HK 1104236A1 HK 07112681 A HK07112681 A HK 07112681A HK 1104236 A1 HK1104236 A1 HK 1104236A1
Authority
HK
Hong Kong
Prior art keywords
etval
meala
cyclosporin
treatment
infection
Prior art date
Application number
HK07112681.2A
Other languages
English (en)
Inventor
Pietro Scalfaro
Jean-Maurice Dumont
Gregoire Vuagniaux
Rolland-Yves R Mauvernay
Original Assignee
Debiopharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm Sa filed Critical Debiopharm Sa
Publication of HK1104236A1 publication Critical patent/HK1104236A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HK07112681.2A 2004-10-01 2007-11-21 Use of [d-meala]3-[etval]4-cyclosporin for the treatment of hepatitis c infection and pharmaceutical composition comprising said [d-meala]3- [etval]4-cyclosporin [d-meala]3-[etval]4 HK1104236A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2004003205 2004-10-01
PCT/IB2005/002940 WO2006038088A1 (en) 2004-10-01 2005-10-03 Use of [d-meala]3-[etval]4-cyclosporin for the treatment of hepatitis c infection and pharmaceutical composition comprising said [d-meala]3-[etval]4-cyclosporin

Publications (1)

Publication Number Publication Date
HK1104236A1 true HK1104236A1 (en) 2008-01-11

Family

ID=34959441

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07112681.2A HK1104236A1 (en) 2004-10-01 2007-11-21 Use of [d-meala]3-[etval]4-cyclosporin for the treatment of hepatitis c infection and pharmaceutical composition comprising said [d-meala]3- [etval]4-cyclosporin [d-meala]3-[etval]4

Country Status (30)

Country Link
US (3) US7439227B2 (xx)
EP (1) EP1793844B1 (xx)
JP (1) JP4892486B2 (xx)
KR (1) KR101191833B1 (xx)
CN (1) CN101056648B (xx)
AT (1) ATE490778T1 (xx)
AU (1) AU2005290984B2 (xx)
BR (1) BRPI0515494A (xx)
CA (1) CA2580448C (xx)
CY (1) CY1114594T1 (xx)
DE (1) DE602005025232D1 (xx)
DK (1) DK1793844T3 (xx)
EA (1) EA012650B1 (xx)
ES (1) ES2357587T3 (xx)
GE (1) GEP20104960B (xx)
HK (1) HK1104236A1 (xx)
HR (1) HRP20110169T1 (xx)
IL (1) IL182362A0 (xx)
MA (1) MA28950B1 (xx)
MX (1) MX2007003387A (xx)
NZ (1) NZ554412A (xx)
PL (1) PL1793844T3 (xx)
PT (1) PT1793844E (xx)
RS (1) RS51614B (xx)
SG (1) SG139750A1 (xx)
SI (1) SI1793844T1 (xx)
TN (1) TNSN07084A1 (xx)
UA (1) UA88484C2 (xx)
WO (1) WO2006038088A1 (xx)
ZA (1) ZA200702610B (xx)

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MX2007000503A (es) 2004-07-14 2007-03-08 Novartis Ag Uso de una combinacion de ciclosporina e interferon pegilado para el tratamiento de hepatitis c(hcv).
US7196161B2 (en) 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
EP1814902B1 (en) 2004-11-22 2008-10-22 Astellas Pharma Inc. Cyclosporine analogue
EP1830871A1 (en) 2004-12-23 2007-09-12 Novartis AG Compositions for hcv treatment
MX2007007721A (es) * 2004-12-23 2007-08-14 Novartis Ag Compuestos para el tratamiento de flaviviridae.
WO2006138507A1 (en) * 2005-06-17 2006-12-28 Novartis Ag Use of sanglifehrin in hcv
US7754685B2 (en) 2005-09-30 2010-07-13 Scynexis, Inc. Methods and pharmaceutical compositions for the treatment and prevention of hepatitis C infection
WO2007041631A1 (en) 2005-09-30 2007-04-12 Scynexis, Inc. ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION
CN101305019B (zh) 2005-10-26 2012-12-12 安斯泰来制药有限公司 新的环肽化合物
NZ571826A (en) 2006-04-11 2012-01-12 Novartis Ag HCV/HIV inhibitors and their uses
CA2652662C (en) 2006-05-19 2015-11-03 Scynexis, Inc. Methods for the treatment and prevention of ocular disorders
WO2008043797A1 (en) * 2006-10-12 2008-04-17 Novartis Ag Use of modified cyclosporins
WO2008069917A2 (en) 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
KR20100017547A (ko) 2007-05-02 2010-02-16 아스텔라스세이야쿠 가부시키가이샤 신규 시클릭 펩티드 화합물
EP2195009B1 (en) 2007-09-26 2014-07-30 Oregon Health and Science University Cyclic undecapeptides and derivatives as multiple sclerosis therapies
WO2009098533A1 (en) * 2008-02-08 2009-08-13 Debiopharm Sa Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy
WO2009148615A1 (en) * 2008-06-06 2009-12-10 Scynexis, Inc. Cyclosporin analogs and their use in the treatment of hcv infections
US9090671B2 (en) 2008-06-06 2015-07-28 Scynexis, Inc. Macrocyclic peptides
UA102414C2 (ru) * 2008-11-06 2013-07-10 Дебио Решерш Фармасьютик С.А. Циклоундекадепсипептидные соединения для лечения инфекций, вызванных вирусом гепатита с
AU2009334790B2 (en) 2008-12-31 2016-09-08 Scynexis, Inc. Derivatives of cyclosporin A
SG173180A1 (en) 2009-01-30 2011-09-29 Enanta Pharm Inc Cyclosporin analogues for preventing or treating hepatitis c infection
US8481483B2 (en) 2009-02-19 2013-07-09 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US20110182850A1 (en) 2009-04-10 2011-07-28 Trixi Brandl Organic compounds and their uses
US8512690B2 (en) 2009-04-10 2013-08-20 Novartis Ag Derivatised proline containing peptide compounds as protease inhibitors
US8367053B2 (en) 2009-07-09 2013-02-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8349312B2 (en) 2009-07-09 2013-01-08 Enanta Pharmaceuticals, Inc. Proline substituted cyclosporin analogues
US8685917B2 (en) 2009-07-09 2014-04-01 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US20110117055A1 (en) 2009-11-19 2011-05-19 Macdonald James E Methods of Treating Hepatitis C Virus with Oxoacetamide Compounds
EP2509615A1 (en) 2009-12-09 2012-10-17 Scynexis, Inc. Novel cyclic peptides
US8623814B2 (en) 2010-02-23 2014-01-07 Enanta Pharmaceuticals, Inc. Antiviral agents
WO2011141891A1 (en) 2010-05-12 2011-11-17 Debio Recherche Pharmaceutique S.A. Use of cycloundecadepsipeptide compounds
CN103153329A (zh) 2010-07-16 2013-06-12 美国科技环球有限公司 新颖的环孢霉素a衍生物在病毒感染的治疗和预防中的应用
US9573978B2 (en) 2010-08-12 2017-02-21 S&T Global, Inc. Cyclosporin derivatives for the treatment and prevention of a viral infection
CN103179974A (zh) * 2010-10-05 2013-06-26 诺华有限公司 丙型肝炎病毒感染的新疗法
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CN103476409A (zh) 2011-03-31 2013-12-25 诺华股份有限公司 治疗丙肝病毒感染的阿拉泊韦
KR20140010097A (ko) 2011-04-01 2014-01-23 노파르티스 아게 B형 간염 바이러스 단독 감염 또는 델타 간염 바이러스와의 조합 감염 및 연관된 간 질환의 치료
EP2696883A1 (en) * 2011-04-13 2014-02-19 Novartis AG Treatment of hepatitis c virus infection with alisporivir
MX2014003753A (es) 2011-09-27 2014-05-01 Novartis Ag Alisporivir para el tratamiento de la infeccion por virus de la hepatitis c.
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
GB2506086A (en) 2011-10-21 2014-03-19 Abbvie Inc Methods for treating HCV comprising at least two direct acting antiviral agent, ribavirin but not interferon
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
CA2811250C (en) 2011-10-21 2015-08-11 Abbvie Inc. Methods for treating hcv
CN104284671A (zh) 2012-05-07 2015-01-14 诺华股份有限公司 使用阿拉泊韦的药代动力学调节
AR090964A1 (es) * 2012-05-09 2014-12-17 Novartis Ag Proceso para la elaboracion de undecapeptidos ciclicos
US8906853B2 (en) 2012-11-28 2014-12-09 Enanta Pharmaceuticals, Inc. [N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection
US20140205566A1 (en) 2012-11-30 2014-07-24 Novartis Ag Cyclic nucleuoside derivatives and uses thereof
WO2015008223A1 (en) 2013-07-17 2015-01-22 Novartis Ag Treatment of hepatitis c virus infection with alisporivir and ribavirin
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Also Published As

Publication number Publication date
BRPI0515494A (pt) 2008-07-29
KR101191833B1 (ko) 2012-10-16
USRE43371E1 (en) 2012-05-08
CA2580448C (en) 2012-09-18
SG139750A1 (en) 2008-02-29
MX2007003387A (es) 2007-05-23
ATE490778T1 (de) 2010-12-15
US20090081164A1 (en) 2009-03-26
EA012650B1 (ru) 2009-12-30
PL1793844T3 (pl) 2011-05-31
JP2008514690A (ja) 2008-05-08
AU2005290984A1 (en) 2006-04-13
CN101056648B (zh) 2012-08-15
JP4892486B2 (ja) 2012-03-07
DE602005025232D1 (de) 2011-01-20
KR20070073761A (ko) 2007-07-10
AU2005290984B2 (en) 2010-09-09
US7439227B2 (en) 2008-10-21
IL182362A0 (en) 2007-07-24
CA2580448A1 (en) 2006-04-13
RS51614B (en) 2011-08-31
CY1114594T1 (el) 2016-10-05
PT1793844E (pt) 2011-03-10
CN101056648A (zh) 2007-10-17
DK1793844T3 (da) 2011-03-21
TNSN07084A1 (en) 2008-06-02
EP1793844A1 (en) 2007-06-13
UA88484C2 (ru) 2009-10-26
EA200700725A1 (ru) 2007-10-26
HRP20110169T1 (hr) 2011-04-30
US7772184B2 (en) 2010-08-10
ES2357587T3 (es) 2011-04-27
MA28950B1 (fr) 2007-10-01
WO2006038088A1 (en) 2006-04-13
US20060252675A1 (en) 2006-11-09
ZA200702610B (en) 2008-08-27
SI1793844T1 (sl) 2011-05-31
NZ554412A (en) 2011-01-28
EP1793844B1 (en) 2010-12-08
GEP20104960B (en) 2010-04-26

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Legal Events

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20171003