HK1101315A1 - Fsh glycosylation mutant fsh - Google Patents

Fsh glycosylation mutant fsh

Info

Publication number
HK1101315A1
HK1101315A1 HK07109465.0A HK07109465A HK1101315A1 HK 1101315 A1 HK1101315 A1 HK 1101315A1 HK 07109465 A HK07109465 A HK 07109465A HK 1101315 A1 HK1101315 A1 HK 1101315A1
Authority
HK
Hong Kong
Prior art keywords
fsh
glycosylation mutant
mutant
glycosylation
lifes
Prior art date
Application number
HK07109465.0A
Other languages
English (en)
Inventor
Louise M Garone
Stephen J Arkinstall
William H Brondyk
Robert K Campbell
Xuliang Jiang
Sean D Mckenna
Mark Tepper
Original Assignee
Merck Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono Sa filed Critical Merck Serono Sa
Publication of HK1101315A1 publication Critical patent/HK1101315A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/59Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK07109465.0A 2003-09-02 2007-08-30 Fsh glycosylation mutant fsh HK1101315A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49980203P 2003-09-02 2003-09-02
PCT/US2004/029042 WO2005020934A2 (en) 2003-09-02 2004-09-02 Fsh glycosylation mutant

Publications (1)

Publication Number Publication Date
HK1101315A1 true HK1101315A1 (en) 2007-10-12

Family

ID=34272871

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07109465.0A HK1101315A1 (en) 2003-09-02 2007-08-30 Fsh glycosylation mutant fsh

Country Status (24)

Country Link
US (1) US7700112B2 (xx)
EP (1) EP1694271B1 (xx)
JP (1) JP4653090B2 (xx)
KR (1) KR101099809B1 (xx)
CN (1) CN1984926B (xx)
AT (1) ATE511829T1 (xx)
AU (1) AU2004268683B2 (xx)
BR (1) BRPI0413206A (xx)
CA (1) CA2535522A1 (xx)
CY (1) CY1112439T1 (xx)
DK (1) DK1694271T3 (xx)
EA (1) EA012175B1 (xx)
ES (1) ES2367784T3 (xx)
HK (1) HK1101315A1 (xx)
HR (1) HRP20110430T1 (xx)
IL (1) IL174037A0 (xx)
MX (1) MXPA06002119A (xx)
NO (1) NO20061446L (xx)
PL (1) PL1694271T3 (xx)
PT (1) PT1694271E (xx)
SI (1) SI1694271T1 (xx)
UA (1) UA88879C2 (xx)
WO (1) WO2005020934A2 (xx)
ZA (1) ZA200601803B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1917276T1 (en) 2005-08-26 2018-05-31 Ares Trading S.A. PROCEDURE FOR PREPARATION OF GLYCOSYLATED INTERFERONE BETA
US8604175B2 (en) 2005-12-09 2013-12-10 Ares Trading S.A. Method for purifying FSH or a FSH mutant
WO2008010840A2 (en) * 2005-12-22 2008-01-24 Laboratoires Serono S.A. Fsh mutants
EA013974B1 (ru) * 2006-01-17 2010-08-30 Мерк Сероно С.А. Мутантный fsh и способы его применения
CN101679525B (zh) * 2007-03-26 2013-06-19 诺瓦提斯公司 用于监测肾功能的预测性的肾安全性生物标志物和生物标志物标签
AR081755A1 (es) 2010-04-02 2012-10-17 Hanmi Holdings Co Ltd Formulacion de accion prolongada de la hormona estimuladora de los foliculos donde se usa un fragmento de inmunoglobulina, metodo de preparacion y metodo para tratar a un sujeto que sufre un trastorno reproductivo
CN108676096B (zh) * 2018-05-22 2022-03-29 北京伟杰信生物科技有限公司 重组猪fsh-ctp融合蛋白及其制备方法与应用
CA3160345A1 (en) * 2019-11-06 2021-05-14 The Regents Of The University Of Colorado, A Body Corporate Modified follicle-stimulating hormone and methods of using the same
CN114213523B (zh) * 2021-11-15 2024-07-09 广州源博医药科技有限公司 一种用于重组蛋白的高糖基化修饰序列及其重组猪促卵泡激素和应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5156957A (en) 1983-11-02 1992-10-20 Genzyme Corporation Follicle stimulating hormone
US5639639A (en) 1983-11-02 1997-06-17 Genzyme Corporation Recombinant heterodimeric human fertility hormones, and methods, cells, vectors and DNA for the production thereof
US4840896A (en) 1983-11-02 1989-06-20 Integrated Genetics, Inc. Heteropolymeric protein
US4923805A (en) 1983-11-02 1990-05-08 Integrated Genetics, Inc. Fsh
US4845077A (en) 1984-04-03 1989-07-04 Serono Laboratories, Inc. Method of inducing ovulation
US4589402A (en) 1984-07-26 1986-05-20 Serono Laboratories, Inc. Method of in vitro fertilization
US5338835A (en) 1989-02-21 1994-08-16 Washington University CTP-extended form of FSH
EP0461200B1 (en) 1989-02-21 1997-01-22 Washington University Modified forms of reproductive hormones
US5508261A (en) 1991-06-18 1996-04-16 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered receptor binding specificity and activity and methods for preparing and using same
US6407205B1 (en) 1997-06-04 2002-06-18 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College FSH-releasing peptides
AU8727798A (en) * 1997-06-20 1999-01-04 Akzo Nobel N.V. Gonadotropin releasing hormone antagonist
PT1102763E (pt) * 1998-08-07 2005-01-31 Applied Research Systems Mimeticos fsh para o tratamento da infertilidade
BR0107881A (pt) 2000-01-27 2003-04-01 Applied Research Systems Uso de fsh tratamento de infertilidade
US20020127652A1 (en) * 2000-02-11 2002-09-12 Schambye Hans Thalsgard Follicle stimulating hormones
WO2001058493A1 (en) * 2000-02-11 2001-08-16 Maxygen Aps Conjugates of follicle stimulating hormones
ES2389835T3 (es) 2001-10-22 2012-11-02 Merck Serono Sa Glicoproteínas mutantes

Also Published As

Publication number Publication date
EP1694271B1 (en) 2011-06-08
EA012175B1 (ru) 2009-08-28
WO2005020934A2 (en) 2005-03-10
BRPI0413206A (pt) 2006-10-03
UA88879C2 (xx) 2009-12-10
CN1984926A (zh) 2007-06-20
ZA200601803B (en) 2007-05-30
MXPA06002119A (es) 2006-05-31
JP4653090B2 (ja) 2011-03-16
US20050100989A1 (en) 2005-05-12
KR20070029620A (ko) 2007-03-14
EA200600526A1 (ru) 2007-04-27
CN1984926B (zh) 2012-04-11
ATE511829T1 (de) 2011-06-15
NO20061446L (no) 2006-03-30
SI1694271T1 (sl) 2011-08-31
AU2004268683A2 (en) 2005-03-10
WO2005020934A3 (en) 2007-02-15
US7700112B2 (en) 2010-04-20
PT1694271E (pt) 2011-07-07
HRP20110430T1 (hr) 2011-07-31
EP1694271A2 (en) 2006-08-30
DK1694271T3 (da) 2011-09-12
AU2004268683B2 (en) 2010-06-24
PL1694271T3 (pl) 2011-11-30
JP2007508245A (ja) 2007-04-05
AU2004268683A1 (en) 2005-03-10
ES2367784T3 (es) 2011-11-08
IL174037A0 (en) 2006-08-01
CY1112439T1 (el) 2015-12-09
KR101099809B1 (ko) 2011-12-27
CA2535522A1 (en) 2005-03-10

Similar Documents

Publication Publication Date Title
HK1101315A1 (en) Fsh glycosylation mutant fsh
AU2003272536A8 (en) Use of a human amniotic membrane composition for prophylaxis and treatment of diseases and conditions of the eye and skin
AU2003264282A1 (en) Phenethanolamine derivatives and their use in the treatment of respiratory diseases
GB0001309D0 (en) Valve arrangement
AU4346401A (en) Human cord blood as a source of neural tissue for repair of the brain and spinalcord
EP1536834A4 (en) DESIGN OF CHEMOKINE ANALOGS FOR THE TREATMENT OF HUMAN DISEASES
IL131084A0 (en) The use of levobupivacaine in facial surgery
EA200870177A1 (ru) Новый гликозилированный вариант fsh d3n
MX2008008322A (es) Mutantes de fsh.
WO2002076313A8 (fr) Extenseur de l'os maxillaire
WO2004050679A3 (en) Mutant glycoproteins
GB2404148B (en) Method of producing a manufactured article in silk indicated in the treatment of some skin diseases of the human body
HUT63441A (en) Megakariocyte colony stimultating factor protein
AU2003281257A8 (en) A novel use of rapamycin and structural analogues thereof
USD467344S1 (en) Treatment couch
GB0202410D0 (en) Treatment of IL deficiencies
CN2345194Y (zh) 一种扣叩器
AU2003232356A1 (en) Improved baby garment
AU2002364889A8 (en) Methods for diagnosis and treatment of diseases associated with altered expression of nrf2
ATE95995T1 (de) Ergonomisches kopfkissen, insbesondere zur verhuetung und/oder behandlung von nackenbeschwerden.
GR990100106A (el) Οργανο παθητικης κινησιοθεραπειας σε ορθια θεση για ατομα με αναπηρια στα κατω ακρα
CA102676S (en) Cot
AU126541S (en) An attachment for a medical examination couch
UA28676A (uk) Спосіб підготовки хворого до стоматологічного втручання
GR980100337A (el) Ιατρικο πτυσσομενο ορθοπεδικο κρεβατι

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160902