DK1694271T3 - FSH-glykosyleringsmutant - Google Patents

FSH-glykosyleringsmutant

Info

Publication number
DK1694271T3
DK1694271T3 DK04783331.4T DK04783331T DK1694271T3 DK 1694271 T3 DK1694271 T3 DK 1694271T3 DK 04783331 T DK04783331 T DK 04783331T DK 1694271 T3 DK1694271 T3 DK 1694271T3
Authority
DK
Denmark
Prior art keywords
fsh
glykosyleringsmutant
mutant
lifes
permits
Prior art date
Application number
DK04783331.4T
Other languages
English (en)
Inventor
Louise M Garone
Stephen J Arkinstall
William H Brondyk
Robert K Campbell
Xuliang Jiang
Sean D Mckenna
Mark Tepper
Original Assignee
Merck Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono Sa filed Critical Merck Serono Sa
Application granted granted Critical
Publication of DK1694271T3 publication Critical patent/DK1694271T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/59Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK04783331.4T 2003-09-02 2004-09-02 FSH-glykosyleringsmutant DK1694271T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49980203P 2003-09-02 2003-09-02
PCT/US2004/029042 WO2005020934A2 (en) 2003-09-02 2004-09-02 Fsh glycosylation mutant

Publications (1)

Publication Number Publication Date
DK1694271T3 true DK1694271T3 (da) 2011-09-12

Family

ID=34272871

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04783331.4T DK1694271T3 (da) 2003-09-02 2004-09-02 FSH-glykosyleringsmutant

Country Status (23)

Country Link
US (1) US7700112B2 (da)
EP (1) EP1694271B1 (da)
JP (1) JP4653090B2 (da)
KR (1) KR101099809B1 (da)
CN (1) CN1984926B (da)
AT (1) ATE511829T1 (da)
AU (1) AU2004268683B2 (da)
BR (1) BRPI0413206A (da)
CA (1) CA2535522A1 (da)
CY (1) CY1112439T1 (da)
DK (1) DK1694271T3 (da)
EA (1) EA012175B1 (da)
ES (1) ES2367784T3 (da)
HR (1) HRP20110430T1 (da)
IL (1) IL174037A0 (da)
MX (1) MXPA06002119A (da)
NO (1) NO20061446L (da)
PL (1) PL1694271T3 (da)
PT (1) PT1694271E (da)
SI (1) SI1694271T1 (da)
UA (1) UA88879C2 (da)
WO (1) WO2005020934A2 (da)
ZA (1) ZA200601803B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA015901B1 (ru) 2005-08-26 2011-12-30 Арес Трейдинг С.А. Способ получения гликозилированного интерферона бета
CA2625978A1 (en) * 2005-12-09 2007-06-14 Ares Trading S.A. Method for purifying fsh or a fsh mutant
KR20080087854A (ko) * 2005-12-22 2008-10-01 라보라토리스 세로노 에스.에이. Fsh 변종
JP2009523445A (ja) * 2006-01-17 2009-06-25 ラボラトワール セローノ ソシエテ アノニム 新規fshグリコシル化変異体d3n
PT2125899E (pt) * 2007-03-26 2013-01-24 Novartis Ag Biomarcadores preditivos de segurança renal e assinaturas de biomarcadores para monitorizar a função renal
AR081755A1 (es) 2010-04-02 2012-10-17 Hanmi Holdings Co Ltd Formulacion de accion prolongada de la hormona estimuladora de los foliculos donde se usa un fragmento de inmunoglobulina, metodo de preparacion y metodo para tratar a un sujeto que sufre un trastorno reproductivo
CN108676096B (zh) * 2018-05-22 2022-03-29 北京伟杰信生物科技有限公司 重组猪fsh-ctp融合蛋白及其制备方法与应用
EP4055038A4 (en) * 2019-11-06 2023-11-15 The Regents of the University of Colorado, a body corporate MODIFIED FOLLICLE-STIMULATING HORMONE AND METHOD OF USE THEREOF
CN114213523B (zh) * 2021-11-15 2024-07-09 广州源博医药科技有限公司 一种用于重组蛋白的高糖基化修饰序列及其重组猪促卵泡激素和应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639639A (en) 1983-11-02 1997-06-17 Genzyme Corporation Recombinant heterodimeric human fertility hormones, and methods, cells, vectors and DNA for the production thereof
US5156957A (en) 1983-11-02 1992-10-20 Genzyme Corporation Follicle stimulating hormone
US4923805A (en) 1983-11-02 1990-05-08 Integrated Genetics, Inc. Fsh
US4840896A (en) 1983-11-02 1989-06-20 Integrated Genetics, Inc. Heteropolymeric protein
US4845077A (en) 1984-04-03 1989-07-04 Serono Laboratories, Inc. Method of inducing ovulation
US4589402A (en) 1984-07-26 1986-05-20 Serono Laboratories, Inc. Method of in vitro fertilization
US5338835A (en) 1989-02-21 1994-08-16 Washington University CTP-extended form of FSH
AU648020B2 (en) 1989-02-21 1994-04-14 Washington University Modified forms of reproductive hormones
US5508261A (en) 1991-06-18 1996-04-16 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered receptor binding specificity and activity and methods for preparing and using same
US6407205B1 (en) * 1997-06-04 2002-06-18 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College FSH-releasing peptides
EP0994718B1 (en) * 1997-06-20 2005-08-17 Akzo Nobel N.V. Gonadotropin releasing hormone antagonist
PT1102763E (pt) 1998-08-07 2005-01-31 Applied Research Systems Mimeticos fsh para o tratamento da infertilidade
US7291593B2 (en) * 2000-01-27 2007-11-06 Laboratoires Serono Sa Use of fish for treating infertility
AU2001231531A1 (en) 2000-02-11 2001-08-20 Maxygen Aps Follicle stimulating hormones
US20020127652A1 (en) * 2000-02-11 2002-09-12 Schambye Hans Thalsgard Follicle stimulating hormones
AU2002368265B2 (en) 2001-10-22 2007-06-07 Merck Serono Sa Mutant glycoproteins

Also Published As

Publication number Publication date
JP2007508245A (ja) 2007-04-05
CN1984926B (zh) 2012-04-11
AU2004268683A1 (en) 2005-03-10
PL1694271T3 (pl) 2011-11-30
ZA200601803B (en) 2007-05-30
EA200600526A1 (ru) 2007-04-27
PT1694271E (pt) 2011-07-07
UA88879C2 (en) 2009-12-10
US7700112B2 (en) 2010-04-20
BRPI0413206A (pt) 2006-10-03
ES2367784T3 (es) 2011-11-08
CY1112439T1 (el) 2015-12-09
MXPA06002119A (es) 2006-05-31
AU2004268683A2 (en) 2005-03-10
WO2005020934A2 (en) 2005-03-10
EP1694271B1 (en) 2011-06-08
AU2004268683B2 (en) 2010-06-24
KR20070029620A (ko) 2007-03-14
JP4653090B2 (ja) 2011-03-16
EA012175B1 (ru) 2009-08-28
US20050100989A1 (en) 2005-05-12
IL174037A0 (en) 2006-08-01
CN1984926A (zh) 2007-06-20
SI1694271T1 (sl) 2011-08-31
NO20061446L (no) 2006-03-30
KR101099809B1 (ko) 2011-12-27
HK1101315A1 (en) 2007-10-12
WO2005020934A3 (en) 2007-02-15
HRP20110430T1 (hr) 2011-07-31
CA2535522A1 (en) 2005-03-10
ATE511829T1 (de) 2011-06-15
EP1694271A2 (en) 2006-08-30

Similar Documents

Publication Publication Date Title
CY1112439T1 (el) Μεταλλαγμα fsh-γλυκοζυλιωσης
AU2003272536A8 (en) Use of a human amniotic membrane composition for prophylaxis and treatment of diseases and conditions of the eye and skin
ATE312635T1 (de) Ventilanordnung
AU2003264282A1 (en) Phenethanolamine derivatives and their use in the treatment of respiratory diseases
ATE299675T1 (de) Einfach an jeden zahnarztstuhl und/oder operationstisch anpassbare armstütze
IL172396A0 (en) Replikin peptides and uses thereof
HUP9900681A2 (hu) TH1/TH2-citokinexpresszió modulálása Ribavirinnel és Ribavirin-analógokkal, aktivált T-limfocitákban
MXPA05001885A (es) El uso de una combinacion de ciclesonida y antihistaminas para el tratamiento de la rinitis alergica.
DE60115432D1 (de) Apoptotische körper zur verwendung in der behandlung von t-zell-vermittelten- und entzündungserkrankungen
NZ528164A (en) Use of flumazenil to produce a medicament for the treatment of cocaine dependency
WO2007084441A3 (en) Novel fsh glycosylation variant d3n
ITTO20020684A1 (it) Nuovo uso dell'angelicina e di suoi analoghi strutturali.
ES2094757T3 (es) Un factor megacariocitopoyetico.
MX2008008322A (es) Mutantes de fsh.
AU2003281257A8 (en) A novel use of rapamycin and structural analogues thereof
WO2004050679A3 (en) Mutant glycoproteins
AU2002364889A8 (en) Methods for diagnosis and treatment of diseases associated with altered expression of nrf2
CN2345194Y (zh) 一种扣叩器
ATE95995T1 (de) Ergonomisches kopfkissen, insbesondere zur verhuetung und/oder behandlung von nackenbeschwerden.
BR8000814U (pt) Instrumento de massagem à vácuo
GR990100106A (el) Οργανο παθητικης κινησιοθεραπειας σε ορθια θεση για ατομα με αναπηρια στα κατω ακρα
SE9704451D0 (sv) New method and compositions for the treatment of autoimmune diseases
TW519919U (en) Structure of health care chair capable of performing therapeutic ch'I-gong with biological spectrum
BR8102461U (pt) Mouse fìsico estimulador
CA102676S (en) Cot