HK1099020A1 - Method of preparing 3-fluorinated quinolines - Google Patents
Method of preparing 3-fluorinated quinolinesInfo
- Publication number
- HK1099020A1 HK1099020A1 HK07106501.2A HK07106501A HK1099020A1 HK 1099020 A1 HK1099020 A1 HK 1099020A1 HK 07106501 A HK07106501 A HK 07106501A HK 1099020 A1 HK1099020 A1 HK 1099020A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- alkyl
- optionally substituted
- protecting group
- quinolines
- fluoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
- B01J23/44—Palladium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oncology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0313384A FR2862301B1 (fr) | 2003-11-17 | 2003-11-17 | Nouveau procede de preparation de quinoleines 3-fluorees |
| PCT/FR2004/002910 WO2005049575A1 (fr) | 2003-11-17 | 2004-11-15 | Nouveau procede de preparation de quinoleines 3-fluorees |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1099020A1 true HK1099020A1 (en) | 2007-08-03 |
Family
ID=34508487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK07106501.2A HK1099020A1 (en) | 2003-11-17 | 2007-06-16 | Method of preparing 3-fluorinated quinolines |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1687276B1 (zh) |
| JP (1) | JP4751333B2 (zh) |
| KR (1) | KR20060123161A (zh) |
| CN (1) | CN100537540C (zh) |
| AT (1) | ATE445605T1 (zh) |
| AU (1) | AU2004291376A1 (zh) |
| CA (1) | CA2542796C (zh) |
| DE (1) | DE602004023640D1 (zh) |
| ES (1) | ES2334796T3 (zh) |
| FR (1) | FR2862301B1 (zh) |
| HK (1) | HK1099020A1 (zh) |
| HR (1) | HRP20060168A2 (zh) |
| IL (1) | IL175649A (zh) |
| IS (1) | IS8423A (zh) |
| MX (1) | MXPA06005599A (zh) |
| NO (1) | NO20062761L (zh) |
| RU (1) | RU2351591C2 (zh) |
| WO (1) | WO2005049575A1 (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7396934B2 (en) | 2003-11-17 | 2008-07-08 | Youssef El-Ahmad | Process for preparing 3-fluoroquinolines |
| CA2750047A1 (en) | 2009-01-21 | 2010-07-29 | Basilea Pharmaceutica Ag | Novel bicyclic antibiotics |
| CN104672131B (zh) * | 2013-11-27 | 2017-03-15 | 中国科学院大连化学物理研究所 | 一种合成3‑氟喹啉衍生物的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA801526B (en) * | 1979-03-26 | 1981-08-26 | Robins Co Inc A H | 4-amino-3-quinolinecarboxylic acids and esters-antisecretory, anti-ulcer compounds |
| DE3620856A1 (de) * | 1986-06-21 | 1987-12-23 | Basf Ag | 3-cyanchinolinderivate |
| DK273689A (da) * | 1988-06-06 | 1989-12-07 | Sanofi Sa | 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler |
| JPH06287187A (ja) * | 1993-04-02 | 1994-10-11 | Nippon Soda Co Ltd | 新規なピラゾ−ル誘導体及びその農園芸用殺菌剤 |
| SE0004056D0 (sv) * | 2000-11-06 | 2000-11-06 | Astrazeneca Ab | N-type calcium channel antagonists for the treatment of pain |
| FR2816618B1 (fr) * | 2000-11-15 | 2002-12-27 | Aventis Pharma Sa | Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent |
| FR2822154B1 (fr) * | 2001-03-13 | 2005-10-21 | Aventis Pharma Sa | Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent |
| TWI275390B (en) * | 2002-04-30 | 2007-03-11 | Wyeth Corp | Process for the preparation of 7-substituted-3- quinolinecarbonitriles |
-
2003
- 2003-11-17 FR FR0313384A patent/FR2862301B1/fr not_active Expired - Fee Related
-
2004
- 2004-11-15 EP EP04805450A patent/EP1687276B1/fr active Active
- 2004-11-15 AU AU2004291376A patent/AU2004291376A1/en not_active Abandoned
- 2004-11-15 DE DE602004023640T patent/DE602004023640D1/de active Active
- 2004-11-15 CN CNB2004800337575A patent/CN100537540C/zh not_active Expired - Fee Related
- 2004-11-15 KR KR1020067009538A patent/KR20060123161A/ko not_active Application Discontinuation
- 2004-11-15 CA CA2542796A patent/CA2542796C/fr not_active Expired - Fee Related
- 2004-11-15 AT AT04805450T patent/ATE445605T1/de not_active IP Right Cessation
- 2004-11-15 JP JP2006538900A patent/JP4751333B2/ja not_active Expired - Fee Related
- 2004-11-15 RU RU2006120275/04A patent/RU2351591C2/ru not_active IP Right Cessation
- 2004-11-15 WO PCT/FR2004/002910 patent/WO2005049575A1/fr active Application Filing
- 2004-11-15 MX MXPA06005599A patent/MXPA06005599A/es active IP Right Grant
- 2004-11-15 ES ES04805450T patent/ES2334796T3/es active Active
-
2006
- 2006-04-21 IS IS8423A patent/IS8423A/is unknown
- 2006-05-09 HR HR20060168A patent/HRP20060168A2/xx not_active Application Discontinuation
- 2006-05-15 IL IL175649A patent/IL175649A/en not_active IP Right Cessation
- 2006-06-13 NO NO20062761A patent/NO20062761L/no not_active Application Discontinuation
-
2007
- 2007-06-16 HK HK07106501.2A patent/HK1099020A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2862301B1 (fr) | 2007-12-21 |
| JP4751333B2 (ja) | 2011-08-17 |
| JP2007511490A (ja) | 2007-05-10 |
| EP1687276A1 (fr) | 2006-08-09 |
| CA2542796A1 (fr) | 2005-06-02 |
| NO20062761L (no) | 2006-08-17 |
| CA2542796C (fr) | 2011-08-02 |
| RU2006120275A (ru) | 2008-01-10 |
| ATE445605T1 (de) | 2009-10-15 |
| ES2334796T3 (es) | 2010-03-16 |
| EP1687276B1 (fr) | 2009-10-14 |
| IL175649A0 (en) | 2006-09-05 |
| HRP20060168A2 (en) | 2006-09-30 |
| FR2862301A1 (fr) | 2005-05-20 |
| IL175649A (en) | 2011-01-31 |
| IS8423A (is) | 2006-04-21 |
| MXPA06005599A (es) | 2007-01-26 |
| WO2005049575A1 (fr) | 2005-06-02 |
| AU2004291376A1 (en) | 2005-06-02 |
| DE602004023640D1 (de) | 2009-11-26 |
| CN100537540C (zh) | 2009-09-09 |
| CN1894216A (zh) | 2007-01-10 |
| RU2351591C2 (ru) | 2009-04-10 |
| KR20060123161A (ko) | 2006-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20131115 |