HK1083837A1 - Pyrroloimidazole derivatives, their preperation, pharmaceutical compositions containing them, and their use as nootropic agents - Google Patents
Pyrroloimidazole derivatives, their preperation, pharmaceutical compositions containing them, and their use as nootropic agentsInfo
- Publication number
- HK1083837A1 HK1083837A1 HK06103951A HK06103951A HK1083837A1 HK 1083837 A1 HK1083837 A1 HK 1083837A1 HK 06103951 A HK06103951 A HK 06103951A HK 06103951 A HK06103951 A HK 06103951A HK 1083837 A1 HK1083837 A1 HK 1083837A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pharmaceutical compositions
- preperation
- compositions containing
- nootropic agents
- action
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000573A ITMI20030573A1 (it) | 2003-03-24 | 2003-03-24 | Composti ad azione nootropica, loro preparazione, |
PCT/EP2004/050339 WO2004085438A2 (en) | 2003-03-24 | 2004-03-22 | Pyrroloimidazole derivatives, their preparation, pharmaceutical composition containing them, and their use as nootropic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1083837A1 true HK1083837A1 (en) | 2006-07-14 |
Family
ID=33042696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06103951A HK1083837A1 (en) | 2003-03-24 | 2006-03-30 | Pyrroloimidazole derivatives, their preperation, pharmaceutical compositions containing them, and their use as nootropic agents |
Country Status (24)
Country | Link |
---|---|
US (3) | US7544705B2 (ja) |
EP (1) | EP1608655B8 (ja) |
JP (1) | JP4920408B2 (ja) |
CN (1) | CN100522963C (ja) |
AT (1) | ATE401327T1 (ja) |
AU (1) | AU2004224087B2 (ja) |
BR (1) | BRPI0408601A (ja) |
CA (1) | CA2520008C (ja) |
CY (1) | CY1108401T1 (ja) |
DE (1) | DE602004015089D1 (ja) |
DK (1) | DK1608655T3 (ja) |
EA (1) | EA009558B1 (ja) |
ES (1) | ES2309534T3 (ja) |
HK (1) | HK1083837A1 (ja) |
HR (1) | HRP20050833A2 (ja) |
IT (1) | ITMI20030573A1 (ja) |
NO (1) | NO20054898L (ja) |
NZ (1) | NZ543154A (ja) |
PL (2) | PL378939A1 (ja) |
PT (1) | PT1608655E (ja) |
RS (1) | RS20050725A (ja) |
SI (1) | SI1608655T1 (ja) |
WO (1) | WO2004085438A2 (ja) |
ZA (1) | ZA200508578B (ja) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20030573A1 (it) * | 2003-03-24 | 2004-09-25 | Nikem Research Srl | Composti ad azione nootropica, loro preparazione, |
EP1925304A1 (en) * | 2006-11-15 | 2008-05-28 | Nikem Research S.R.L. | Pyrrolo[1,2-a]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents |
AU2012201853B2 (en) * | 2007-04-16 | 2013-06-27 | Neurotune Ag | Use of dimiracetam in the treatment of chronic pain |
ITMI20070770A1 (it) * | 2007-04-16 | 2008-10-17 | Brane Discovery S R L | Impiego di dimiracetam nel trattamento del dolore cronico |
EP3260118B1 (en) | 2008-10-16 | 2021-03-24 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
US9125898B2 (en) | 2008-11-14 | 2015-09-08 | Neurotune Ag | Acetam derivatives for pain relief |
WO2011100373A1 (en) * | 2010-02-09 | 2011-08-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
PL2598504T3 (pl) * | 2010-07-26 | 2014-10-31 | Neurotune Ag | Sposób otrzymywania dimiracetamu |
US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
CN105142623A (zh) | 2013-03-15 | 2015-12-09 | 艾吉因生物股份有限公司 | 用于改善认知功能的方法和组合物 |
EP2968237A4 (en) | 2013-03-15 | 2016-08-31 | Univ Johns Hopkins | METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION |
US10159648B2 (en) | 2015-05-22 | 2018-12-25 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
JOP20190251A1 (ar) | 2017-05-31 | 2019-10-21 | Metys Pharmaceuticals AG | تركيبات تآزرية تشتمل على (r)-ديميراسيتام (1) و(s)-ديميراسيتام (2) بنسبة غير راسيمية |
BR112021010796A2 (pt) | 2018-12-04 | 2021-08-24 | Metys Pharmaceuticals AG | Composições sinérgicas compreendendo r-2-(sulfonil substituído)-hexahidro-pirrolo[1,2-a]pirazin-6(2h)-onas e s-2- (sulfonil substituído)-hexahidro-pirrolo[1,2-a]pirazin-6(2h)-onas em uma relação não racêmica |
WO2020115093A1 (en) | 2018-12-04 | 2020-06-11 | Metys Pharmaceuticals AG | Synergistic compositions comprising (r)-2-(2-oxopyrrolidin-1-yl)butanamide and (s)-2-(2-oxopyrrolidin-1-yl)butanamide in a non-racemic ratio |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4582838A (en) | 1984-08-24 | 1986-04-15 | Warner-Lambert Company | Derivatives of dihydro-1H-pyrrolo[1,2-c]imidazol-3,5-dione as cognition activators |
US5200406A (en) * | 1988-02-08 | 1993-04-06 | I.S.F. Societa Per Azioni | Pharmaceutically useful 2,5-dioxo-1H-octahydroimidazo[1,2-A]azepines |
IT1233860B (it) * | 1988-02-08 | 1992-04-21 | Isf Spa | Derivati del peridroazacicloalca (1,2-a) imidazolo ad attivita' nootropa |
JP3400466B2 (ja) * | 1991-10-28 | 2003-04-28 | 日本水産株式会社 | 高純度エイコサペンタエン酸またはそのエステルの製造方法 |
GB9123641D0 (en) | 1991-11-07 | 1992-01-02 | Isf Spa | Process |
ITMI20030573A1 (it) * | 2003-03-24 | 2004-09-25 | Nikem Research Srl | Composti ad azione nootropica, loro preparazione, |
EP1925304A1 (en) * | 2006-11-15 | 2008-05-28 | Nikem Research S.R.L. | Pyrrolo[1,2-a]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents |
-
2003
- 2003-03-24 IT IT000573A patent/ITMI20030573A1/it unknown
-
2004
- 2004-03-22 PL PL378939A patent/PL378939A1/pl unknown
- 2004-03-22 NZ NZ543154A patent/NZ543154A/en unknown
- 2004-03-22 PL PL04741432T patent/PL1608655T3/pl unknown
- 2004-03-22 CA CA2520008A patent/CA2520008C/en not_active Expired - Fee Related
- 2004-03-22 EP EP04741432A patent/EP1608655B8/en not_active Expired - Lifetime
- 2004-03-22 AU AU2004224087A patent/AU2004224087B2/en not_active Ceased
- 2004-03-22 DK DK04741432T patent/DK1608655T3/da active
- 2004-03-22 BR BRPI0408601-5A patent/BRPI0408601A/pt not_active Application Discontinuation
- 2004-03-22 AT AT04741432T patent/ATE401327T1/de not_active IP Right Cessation
- 2004-03-22 WO PCT/EP2004/050339 patent/WO2004085438A2/en active IP Right Grant
- 2004-03-22 ES ES04741432T patent/ES2309534T3/es not_active Expired - Lifetime
- 2004-03-22 CN CNB2004800055916A patent/CN100522963C/zh not_active Expired - Fee Related
- 2004-03-22 JP JP2006505479A patent/JP4920408B2/ja not_active Expired - Fee Related
- 2004-03-22 US US10/550,483 patent/US7544705B2/en not_active Expired - Fee Related
- 2004-03-22 EA EA200501501A patent/EA009558B1/ru not_active IP Right Cessation
- 2004-03-22 DE DE602004015089T patent/DE602004015089D1/de not_active Expired - Lifetime
- 2004-03-22 SI SI200430868T patent/SI1608655T1/sl unknown
- 2004-03-22 RS YUP-2005/0725A patent/RS20050725A/sr unknown
- 2004-03-22 PT PT04741432T patent/PT1608655E/pt unknown
-
2005
- 2005-09-22 HR HR20050833A patent/HRP20050833A2/hr not_active Application Discontinuation
- 2005-10-21 ZA ZA200508578A patent/ZA200508578B/en unknown
- 2005-10-24 NO NO20054898A patent/NO20054898L/no not_active Application Discontinuation
-
2006
- 2006-03-30 HK HK06103951A patent/HK1083837A1/xx not_active IP Right Cessation
-
2008
- 2008-10-08 CY CY20081101113T patent/CY1108401T1/el unknown
-
2009
- 2009-02-13 US US12/378,475 patent/US7732473B2/en not_active Expired - Fee Related
-
2010
- 2010-02-17 US US12/658,973 patent/US20100173945A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20120322 |