PL1608655T3 - Pochodne piroloimidazolowe, ich wytwarzanie, zawierające je kompozycje farmaceutyczne i ich zastosowanie jako środków o działaniu nootropowym - Google Patents
Pochodne piroloimidazolowe, ich wytwarzanie, zawierające je kompozycje farmaceutyczne i ich zastosowanie jako środków o działaniu nootropowymInfo
- Publication number
- PL1608655T3 PL1608655T3 PL04741432T PL04741432T PL1608655T3 PL 1608655 T3 PL1608655 T3 PL 1608655T3 PL 04741432 T PL04741432 T PL 04741432T PL 04741432 T PL04741432 T PL 04741432T PL 1608655 T3 PL1608655 T3 PL 1608655T3
- Authority
- PL
- Poland
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- nootropic agents
- action
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000002664 nootropic agent Substances 0.000 title 1
- MHOZZUICEDXVGD-UHFFFAOYSA-N pyrrolo[2,3-d]imidazole Chemical class C1=NC2=CC=NC2=N1 MHOZZUICEDXVGD-UHFFFAOYSA-N 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003070 anti-hyperalgesia Effects 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 230000007278 cognition impairment Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001777 nootropic effect Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000573A ITMI20030573A1 (it) | 2003-03-24 | 2003-03-24 | Composti ad azione nootropica, loro preparazione, |
| PCT/EP2004/050339 WO2004085438A2 (en) | 2003-03-24 | 2004-03-22 | Pyrroloimidazole derivatives, their preparation, pharmaceutical composition containing them, and their use as nootropic agents |
| EP04741432A EP1608655B8 (en) | 2003-03-24 | 2004-03-22 | Pyrroloimidazole derivatives, their preparation, pharmaceutical compositions containing them, and their use as nootropic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1608655T3 true PL1608655T3 (pl) | 2009-03-31 |
Family
ID=33042696
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL378939A PL378939A1 (pl) | 2003-03-24 | 2004-03-22 | Związki z działaniem nootropowym, ich wytwarzanie, zawierające je kompozycje farmaceutyczne i ich zastosowanie |
| PL04741432T PL1608655T3 (pl) | 2003-03-24 | 2004-03-22 | Pochodne piroloimidazolowe, ich wytwarzanie, zawierające je kompozycje farmaceutyczne i ich zastosowanie jako środków o działaniu nootropowym |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL378939A PL378939A1 (pl) | 2003-03-24 | 2004-03-22 | Związki z działaniem nootropowym, ich wytwarzanie, zawierające je kompozycje farmaceutyczne i ich zastosowanie |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US7544705B2 (pl) |
| EP (1) | EP1608655B8 (pl) |
| JP (1) | JP4920408B2 (pl) |
| CN (1) | CN100522963C (pl) |
| AT (1) | ATE401327T1 (pl) |
| AU (1) | AU2004224087B2 (pl) |
| BR (1) | BRPI0408601A (pl) |
| CA (1) | CA2520008C (pl) |
| CY (1) | CY1108401T1 (pl) |
| DE (1) | DE602004015089D1 (pl) |
| DK (1) | DK1608655T3 (pl) |
| EA (1) | EA009558B1 (pl) |
| ES (1) | ES2309534T3 (pl) |
| HR (1) | HRP20050833A2 (pl) |
| IT (1) | ITMI20030573A1 (pl) |
| NO (1) | NO20054898L (pl) |
| NZ (1) | NZ543154A (pl) |
| PL (2) | PL378939A1 (pl) |
| PT (1) | PT1608655E (pl) |
| RS (1) | RS20050725A (pl) |
| SI (1) | SI1608655T1 (pl) |
| WO (1) | WO2004085438A2 (pl) |
| ZA (1) | ZA200508578B (pl) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20030573A1 (it) * | 2003-03-24 | 2004-09-25 | Nikem Research Srl | Composti ad azione nootropica, loro preparazione, |
| EP1925304A1 (en) * | 2006-11-15 | 2008-05-28 | Nikem Research S.R.L. | Pyrrolo[1,2-a]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents |
| ITMI20070770A1 (it) * | 2007-04-16 | 2008-10-17 | Brane Discovery S R L | Impiego di dimiracetam nel trattamento del dolore cronico |
| AU2012201853B2 (en) * | 2007-04-16 | 2013-06-27 | Neurotune Ag | Use of dimiracetam in the treatment of chronic pain |
| EP2346500B1 (en) | 2008-10-16 | 2017-05-17 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| US9125898B2 (en) | 2008-11-14 | 2015-09-08 | Neurotune Ag | Acetam derivatives for pain relief |
| EP2533645B1 (en) * | 2010-02-09 | 2016-07-27 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| PL2598504T3 (pl) * | 2010-07-26 | 2014-10-31 | Neurotune Ag | Sposób otrzymywania dimiracetamu |
| US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| US10806717B2 (en) | 2013-03-15 | 2020-10-20 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| CA2904767C (en) | 2013-03-15 | 2022-06-21 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
| EA034167B8 (ru) | 2015-05-22 | 2021-04-27 | Эйджинбайо, Инк. | Фармацевтические композиции леветирацетама пролонгированного высвобождения |
| JOP20190251A1 (ar) | 2017-05-31 | 2019-10-21 | Metys Pharmaceuticals AG | تركيبات تآزرية تشتمل على (r)-ديميراسيتام (1) و(s)-ديميراسيتام (2) بنسبة غير راسيمية |
| EA202191486A1 (ru) | 2018-12-04 | 2021-09-14 | Метис Фармасьютиклз Аг | СИНЕРГЕТИЧЕСКИЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ R-2-(ЗАМЕЩЕННЫЙ СУЛЬФОНИЛ)ГЕКСАГИДРОПИРРОЛО[1,2-а]ПИРАЗИН-6(2H)ОНЫ И S-2-(ЗАМЕЩЕННЫЙ СУЛЬФОНИЛ)ГЕКСАГИДРОПИРРОЛО[1,2-а]ПИРАЗИН-6(2H)ОНЫ В НЕРАЦЕМИЧЕСКОМ СООТНОШЕНИИ |
| JP2022510363A (ja) | 2018-12-04 | 2022-01-26 | メティス ファーマシューティカルズ アクチェンゲゼルシャフト | （ｒ）－２－（２－オキソピロリジン－１－イル）ブタンアミドと（ｓ）－２－（２－オキソピロリジン－１－イル）ブタンアミドを非ラセミ比で含む相乗的組成物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4582838A (en) | 1984-08-24 | 1986-04-15 | Warner-Lambert Company | Derivatives of dihydro-1H-pyrrolo[1,2-c]imidazol-3,5-dione as cognition activators |
| IT1233860B (it) * | 1988-02-08 | 1992-04-21 | Isf Spa | Derivati del peridroazacicloalca (1,2-a) imidazolo ad attivita' nootropa |
| US5200406A (en) * | 1988-02-08 | 1993-04-06 | I.S.F. Societa Per Azioni | Pharmaceutically useful 2,5-dioxo-1H-octahydroimidazo[1,2-A]azepines |
| JP3400466B2 (ja) * | 1991-10-28 | 2003-04-28 | 日本水産株式会社 | 高純度エイコサペンタエン酸またはそのエステルの製造方法 |
| GB9123641D0 (en) | 1991-11-07 | 1992-01-02 | Isf Spa | Process |
| ITMI20030573A1 (it) * | 2003-03-24 | 2004-09-25 | Nikem Research Srl | Composti ad azione nootropica, loro preparazione, |
| EP1925304A1 (en) * | 2006-11-15 | 2008-05-28 | Nikem Research S.R.L. | Pyrrolo[1,2-a]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents |
-
2003
- 2003-03-24 IT IT000573A patent/ITMI20030573A1/it unknown
-
2004
- 2004-03-22 PL PL378939A patent/PL378939A1/pl unknown
- 2004-03-22 SI SI200430868T patent/SI1608655T1/sl unknown
- 2004-03-22 PL PL04741432T patent/PL1608655T3/pl unknown
- 2004-03-22 NZ NZ543154A patent/NZ543154A/en unknown
- 2004-03-22 AU AU2004224087A patent/AU2004224087B2/en not_active Ceased
- 2004-03-22 PT PT04741432T patent/PT1608655E/pt unknown
- 2004-03-22 ES ES04741432T patent/ES2309534T3/es not_active Expired - Lifetime
- 2004-03-22 BR BRPI0408601-5A patent/BRPI0408601A/pt not_active Application Discontinuation
- 2004-03-22 RS YUP-2005/0725A patent/RS20050725A/sr unknown
- 2004-03-22 AT AT04741432T patent/ATE401327T1/de not_active IP Right Cessation
- 2004-03-22 JP JP2006505479A patent/JP4920408B2/ja not_active Expired - Fee Related
- 2004-03-22 EP EP04741432A patent/EP1608655B8/en not_active Expired - Lifetime
- 2004-03-22 DK DK04741432T patent/DK1608655T3/da active
- 2004-03-22 HR HR20050833A patent/HRP20050833A2/hr not_active Application Discontinuation
- 2004-03-22 US US10/550,483 patent/US7544705B2/en not_active Expired - Fee Related
- 2004-03-22 CN CNB2004800055916A patent/CN100522963C/zh not_active Expired - Fee Related
- 2004-03-22 DE DE602004015089T patent/DE602004015089D1/de not_active Expired - Lifetime
- 2004-03-22 CA CA2520008A patent/CA2520008C/en not_active Expired - Fee Related
- 2004-03-22 WO PCT/EP2004/050339 patent/WO2004085438A2/en not_active Ceased
- 2004-03-22 EA EA200501501A patent/EA009558B1/ru not_active IP Right Cessation
-
2005
- 2005-10-21 ZA ZA200508578A patent/ZA200508578B/en unknown
- 2005-10-24 NO NO20054898A patent/NO20054898L/no not_active Application Discontinuation
-
2008
- 2008-10-08 CY CY20081101113T patent/CY1108401T1/el unknown
-
2009
- 2009-02-13 US US12/378,475 patent/US7732473B2/en not_active Expired - Fee Related
-
2010
- 2010-02-17 US US12/658,973 patent/US20100173945A1/en not_active Abandoned
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