HK1081855A1 - Administration form for pharmaceutically active peptides with sustained release and method for the production thereof - Google Patents

Administration form for pharmaceutically active peptides with sustained release and method for the production thereof

Info

Publication number
HK1081855A1
HK1081855A1 HK06102131.0A HK06102131A HK1081855A1 HK 1081855 A1 HK1081855 A1 HK 1081855A1 HK 06102131 A HK06102131 A HK 06102131A HK 1081855 A1 HK1081855 A1 HK 1081855A1
Authority
HK
Hong Kong
Prior art keywords
production
sustained release
pharmaceutically active
active peptides
administration form
Prior art date
Application number
HK06102131.0A
Other languages
English (en)
Inventor
Horst Bauer
Thomas Reissmann
Peter Romeis
Berthold Roessler
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10245525A external-priority patent/DE10245525A1/de
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of HK1081855A1 publication Critical patent/HK1081855A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
HK06102131.0A 2002-09-27 2006-02-17 Administration form for pharmaceutically active peptides with sustained release and method for the production thereof HK1081855A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US41422502P 2002-09-27 2002-09-27
DE10245525A DE10245525A1 (de) 2002-09-27 2002-09-27 Darreichungsform für pharmazeutisch aktive Peptide mit anhaltender Wirkstofffreigabe (sustained release) und Verfahren zu deren Herstellung
DE10320051 2003-04-26
PCT/EP2003/010732 WO2004030650A2 (fr) 2002-09-27 2003-09-26 Forme d'administration de peptides pharmaceutiquement actifs avec liberation prolongee du principe actif et son procede de production

Publications (1)

Publication Number Publication Date
HK1081855A1 true HK1081855A1 (en) 2006-05-26

Family

ID=43646377

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06102131.0A HK1081855A1 (en) 2002-09-27 2006-02-17 Administration form for pharmaceutically active peptides with sustained release and method for the production thereof

Country Status (23)

Country Link
US (1) US7884071B2 (fr)
EP (1) EP1565160B1 (fr)
JP (1) JP4898118B2 (fr)
KR (1) KR100633280B1 (fr)
CN (1) CN100509053C (fr)
AU (1) AU2003287950B2 (fr)
BR (1) BRPI0314546B8 (fr)
CA (1) CA2507524C (fr)
DK (1) DK1565160T3 (fr)
ES (1) ES2457019T3 (fr)
HK (1) HK1081855A1 (fr)
HR (1) HRP20050371B1 (fr)
IL (1) IL167415A (fr)
IS (1) IS7750A (fr)
ME (1) ME00509B (fr)
MX (1) MXPA05003318A (fr)
NO (1) NO338309B1 (fr)
NZ (1) NZ538928A (fr)
PL (1) PL208073B1 (fr)
RS (2) RS20050247A (fr)
RU (1) RU2333743C2 (fr)
WO (1) WO2004030650A2 (fr)
ZA (1) ZA200502150B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1984024A2 (fr) * 2006-01-05 2008-10-29 Novartis AG Méthodes pour prévenir et traiter des métastases de cancer et des pertes osseuses associées à des métastases de cancer
US20070219811A1 (en) * 2006-03-16 2007-09-20 Kim John S Method for using an internet-based CRM application to create an on-line leads marketplace
EP1891964A1 (fr) * 2006-08-08 2008-02-27 AEterna Zentaris GmbH Utilisation de doses initiales d'analogues de LHRH et doses de maintenance d'antagonistes de LHRH pour le traitement de cancers dépendant des hormones
CA2671925A1 (fr) * 2006-12-21 2008-07-10 Stryker Corporation Formulations a liberation entretenue comprenant des cristaux, des gels macromoleculaires et des suspensions particulaires d'agents biologiques
EP2252627B1 (fr) 2008-01-24 2017-04-19 Esperance Pharmaceuticals Produits de fusion recombinants à domaine lytique et leurs procédés de fabrication et d'utilisation
TWI539959B (zh) 2008-02-11 2016-07-01 菲瑞茵國際中心股份有限公司 治療轉移階段攝護腺癌的方法
US8324347B2 (en) * 2009-02-24 2012-12-04 Institute For Systems Biology Methods of using halogenated peptides as internal standards for liquid chromatography-mass spectrometry
WO2010125468A1 (fr) * 2009-05-01 2010-11-04 Ferring International Center Sa Composition pour le traitement d'un cancer de la prostate
NZ600891A (en) 2010-01-13 2014-05-30 Ipsen Pharma Sas Process for the preparation of pharmaceutical compositions for the sustained release of somatostatin analogs
CN102204889B (zh) * 2011-05-23 2013-09-18 蚌埠丰原涂山制药有限公司 一种醋酸地加瑞克冻干粉针剂及其制备方法
MX364010B (es) * 2012-06-01 2019-04-11 Ferring Bv Manufactura de degarelix.
ITMI20121638A1 (it) * 2012-10-02 2014-04-03 Marco Sbracia Utilizzo di degarelix nel trattamento dell'endometriosi e di patologie ad essa correlate
EP4035685A1 (fr) 2012-10-30 2022-08-03 Esperance Pharmaceuticals, Inc. Conjugués anticorps-médicament et procédés d'utilisation
AR101476A1 (es) 2014-08-07 2016-12-21 Acerta Pharma Bv Métodos para tratar cánceres, enfermedades inmunes y autoinmunes, y enfermedades inflamatorias en base a la tasa de ocupación de la tirosin quinasa de bruton (btk) y a la tasa de resíntesis de la tirosin quinasa de bruton (btk)
UA127018C2 (uk) * 2017-01-31 2023-03-15 Веру Інк. КОМПОЗИЦІЇ ТА СПОСОБИ ТРИВАЛОГО ВИВІЛЬНЕННЯ АНТАГОНІСТІВ ГОНАДОТРОПІН-ВИВІЛЬНЯЮЧОГО ГОРМОНА (GnRH)
MX2020002247A (es) * 2017-09-27 2021-03-25 Novel Pharma Inc Derivado de gnrh de conjugado a ácido palmítico de larga duración y composición farmacéutica que lo contiene.
KR102408886B1 (ko) * 2018-01-31 2022-06-14 저장 산후아 클라이메이트 앤드 어플라이언스 컨트롤스 그룹 컴퍼니 리미티드 밸브 코어 조립체

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US5411951A (en) * 1984-10-04 1995-05-02 Monsanto Company Prolonged release of biologically active somatotropin
GB9108634D0 (en) * 1991-04-23 1991-06-12 Ciba Geigy Pharmaceutical compositions
US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
DE4305225A1 (de) 1993-02-19 1994-08-25 Asta Medica Ag Neues Herstellverfahren für Cetrorelix Lyophilisat
DE4342091A1 (de) * 1993-12-09 1995-06-14 Asta Medica Ag Erzeugnisse zur Anwendung von initial hohen Dosen von Cetrorelix und Herstellung einer Kombinationspackung zur Verwendung bei Therapie von Krankheiten
US5595760A (en) * 1994-09-02 1997-01-21 Delab Sustained release of peptides from pharmaceutical compositions
US5942493A (en) * 1995-11-28 1999-08-24 Asta Medica Aktiengesellschaft LH-RH antagonists having improved action
US5916582A (en) * 1996-07-03 1999-06-29 Alza Corporation Aqueous formulations of peptides
NZ334236A (en) * 1996-08-30 2000-06-23 Peptech Ltd Composition comprising GnRH, lecithin and stearin
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
FR2776520B1 (fr) 1998-03-25 2000-05-05 Sod Conseils Rech Applic Nouvelles compositions pharmaceutiques destinees a la liberation prolongee de peptides et leur procede de preparation
CN1243543C (zh) * 1998-07-20 2006-03-01 派普泰克有限公司 生物植入物配方
CO5160256A1 (es) * 1999-02-08 2002-05-30 Zentaris Ag Sales de peptidos farmaceuticamente activos para la liberacion sostenida y proceso de produccion
DE19911771B4 (de) * 1999-03-17 2006-03-30 Zentaris Gmbh LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung
US7005418B1 (en) * 1999-09-23 2006-02-28 Zentaris Gmbh Method for the therapeutic management of extrauterine proliferation of endometrial tissue, chronic pelvic pain and fallopian tube obstruction
US6635739B2 (en) * 1999-10-15 2003-10-21 Theresa Siler-Khodr Non-mammalian GnRH analogs and uses thereof in regulation of fertility and pregnancy
DE10024451A1 (de) * 2000-05-18 2001-11-29 Asta Medica Ag Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
GB0117057D0 (en) 2001-07-12 2001-09-05 Ferring Bv Pharmaceutical composition
EP1674082A1 (fr) * 2004-12-22 2006-06-28 Zentaris GmbH Procédé pour la manufacture des suspensions ou lyophilisates steriles des complexes mal-soluble de peptides basic, des formulations pharmaceutiques avec ces complexes et leur utilisation comme medicament

Also Published As

Publication number Publication date
NZ538928A (en) 2006-10-27
JP2006505538A (ja) 2006-02-16
BR0314546A (pt) 2005-08-09
WO2004030650A3 (fr) 2004-07-15
BRPI0314546B8 (pt) 2021-05-25
DK1565160T3 (da) 2014-04-28
CA2507524A1 (fr) 2004-04-15
HRP20050371A2 (en) 2005-06-30
RS52966B (en) 2014-02-28
KR100633280B1 (ko) 2006-10-16
RU2333743C2 (ru) 2008-09-20
EP1565160A2 (fr) 2005-08-24
AU2003287950A1 (en) 2004-04-23
CA2507524C (fr) 2012-12-11
CN1684703A (zh) 2005-10-19
WO2004030650A2 (fr) 2004-04-15
PL376446A1 (en) 2005-12-27
US7884071B2 (en) 2011-02-08
US20050282731A1 (en) 2005-12-22
IL167415A (en) 2014-05-28
BRPI0314546A8 (pt) 2015-12-15
ZA200502150B (en) 2005-11-30
ME00509B (fr) 2011-10-10
RS20050247A (en) 2007-06-04
JP4898118B2 (ja) 2012-03-14
NO20052041L (no) 2005-06-10
RU2005113163A (ru) 2005-10-10
ES2457019T3 (es) 2014-04-24
NO338309B1 (no) 2016-08-08
AU2003287950B2 (en) 2009-01-29
PL208073B1 (pl) 2011-03-31
EP1565160B1 (fr) 2014-01-22
MXPA05003318A (es) 2005-09-12
HRP20050371B1 (hr) 2014-09-26
KR20050084829A (ko) 2005-08-29
IS7750A (is) 2005-03-17
CN100509053C (zh) 2009-07-08
BRPI0314546B1 (pt) 2020-04-07

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Legal Events

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PE Patent expired

Effective date: 20230921