HK1078781A1 - Processes for preparing 1,3-dioxolane nucleosides - Google Patents
Processes for preparing 1,3-dioxolane nucleosidesInfo
- Publication number
- HK1078781A1 HK1078781A1 HK05110765.7A HK05110765A HK1078781A1 HK 1078781 A1 HK1078781 A1 HK 1078781A1 HK 05110765 A HK05110765 A HK 05110765A HK 1078781 A1 HK1078781 A1 HK 1078781A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- preparing
- processes
- dioxolane nucleosides
- nucleosides
- dioxolane
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/20—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40165502P | 2002-08-06 | 2002-08-06 | |
| PCT/US2003/024986 WO2004028445A2 (en) | 2002-08-06 | 2003-08-06 | Processes for preparing 1,3-dioxolane nucleosides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1078781A1 true HK1078781A1 (en) | 2006-03-24 |
Family
ID=32043165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK05110765.7A HK1078781A1 (en) | 2002-08-06 | 2005-11-25 | Processes for preparing 1,3-dioxolane nucleosides |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6855821B2 (es) |
| EP (1) | EP1534255B1 (es) |
| JP (1) | JP4560407B2 (es) |
| KR (1) | KR101108115B1 (es) |
| AT (1) | ATE496054T1 (es) |
| AU (1) | AU2003294212B2 (es) |
| BR (1) | BR0313302A (es) |
| CA (1) | CA2494183C (es) |
| DE (1) | DE60335805D1 (es) |
| ES (1) | ES2360096T3 (es) |
| HK (1) | HK1078781A1 (es) |
| IL (2) | IL166682A0 (es) |
| MX (1) | MXPA05001451A (es) |
| WO (1) | WO2004028445A2 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100406017C (zh) * | 2002-12-09 | 2008-07-30 | 佐治亚大学研究基金会 | 用于对抗hiv抗性株的二氧戊环基胸腺嘧啶及其组合物 |
| ES2586668T3 (es) | 2003-05-30 | 2016-10-18 | Gilead Pharmasset Llc | Análogos de nucleósidos fluorados modificados |
| US7785839B2 (en) | 2004-02-03 | 2010-08-31 | Emory University | Methods to manufacture 1,3-dioxolane nucleosides |
| US7956087B2 (en) * | 2005-04-21 | 2011-06-07 | Kao Corporation | Cosmetic composition for skin and wrinkle improver |
| AU2009223833A1 (en) * | 2008-03-03 | 2009-09-17 | Stiefel Laboratories, Inc. | Processes for preparing enantiomerically pure diol and dioxolane compounds |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3028519A1 (de) * | 1980-07-28 | 1982-02-25 | Dynamit Nobel Ag, 5210 Troisdorf | Substituierte 2,5,7-trioxan-bicyclo (2.2.2) octan-6-one und 3,6,8-trioxa-bicyclo (3.2.1) octan-4-one und verfahren zu deren herstellung |
| US5047407A (en) | 1989-02-08 | 1991-09-10 | Iaf Biochem International, Inc. | 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties |
| US5204466A (en) | 1990-02-01 | 1993-04-20 | Emory University | Method and compositions for the synthesis of bch-189 and related compounds |
| US5276151A (en) | 1990-02-01 | 1994-01-04 | Emory University | Method of synthesis of 1,3-dioxolane nucleosides |
| US5925643A (en) * | 1990-12-05 | 1999-07-20 | Emory University | Enantiomerically pure β-D-dioxolane-nucleosides |
| IT1244501B (it) | 1991-03-22 | 1994-07-15 | Sigma Tau Ind Farmaceuti | Derivati amminoacilici e oligopeptidici dell'allopurinolo dotati di attivita' immunostimolante e composizioni farmaceutiche che li contengono |
| ZA923640B (en) | 1991-05-21 | 1993-02-24 | Iaf Biochem Int | Processes for the diastereoselective synthesis of nucleosides |
| GB9525606D0 (en) | 1995-12-14 | 1996-02-14 | Iaf Biochem Int | Method and compositions for the synthesis of dioxolane nucleosides with - configuration |
| US5792773A (en) * | 1996-11-15 | 1998-08-11 | Yale University | L-β-dioxolane uridine analog administration for treating Epstein-Barr virus infection |
| IT1301977B1 (it) * | 1998-07-31 | 2000-07-20 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione di r-(-)-carnitina |
| ES2232169T3 (es) | 1998-08-12 | 2005-05-16 | Gilead Sciences, Inc. | Procedimiento de fabricacion de nucleosidos de 1,3-oxatiolano. |
| ATE254126T1 (de) | 1998-12-23 | 2003-11-15 | Shire Biochem Inc | Antivirale nukleosidanaloga |
-
2003
- 2003-08-06 CA CA2494183A patent/CA2494183C/en not_active Expired - Fee Related
- 2003-08-06 IL IL16668203A patent/IL166682A0/xx unknown
- 2003-08-06 AT AT03789692T patent/ATE496054T1/de not_active IP Right Cessation
- 2003-08-06 WO PCT/US2003/024986 patent/WO2004028445A2/en active Application Filing
- 2003-08-06 EP EP03789692A patent/EP1534255B1/en not_active Expired - Lifetime
- 2003-08-06 KR KR1020057002178A patent/KR101108115B1/ko not_active IP Right Cessation
- 2003-08-06 BR BR0313302-8A patent/BR0313302A/pt not_active IP Right Cessation
- 2003-08-06 AU AU2003294212A patent/AU2003294212B2/en not_active Ceased
- 2003-08-06 ES ES03789692T patent/ES2360096T3/es not_active Expired - Lifetime
- 2003-08-06 US US10/635,971 patent/US6855821B2/en not_active Expired - Fee Related
- 2003-08-06 JP JP2004539827A patent/JP4560407B2/ja not_active Expired - Fee Related
- 2003-08-06 DE DE60335805T patent/DE60335805D1/de not_active Expired - Lifetime
- 2003-08-06 MX MXPA05001451A patent/MXPA05001451A/es active IP Right Grant
-
2005
- 2005-02-03 IL IL166682A patent/IL166682A/en not_active IP Right Cessation
- 2005-11-25 HK HK05110765.7A patent/HK1078781A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006504703A (ja) | 2006-02-09 |
| JP4560407B2 (ja) | 2010-10-13 |
| EP1534255A4 (en) | 2006-10-18 |
| AU2003294212A1 (en) | 2004-04-19 |
| AU2003294212B2 (en) | 2010-01-07 |
| WO2004028445A2 (en) | 2004-04-08 |
| BR0313302A (pt) | 2005-06-28 |
| IL166682A (en) | 2011-06-30 |
| ES2360096T3 (es) | 2011-05-31 |
| EP1534255A2 (en) | 2005-06-01 |
| CA2494183C (en) | 2012-01-03 |
| WO2004028445A3 (en) | 2004-06-10 |
| ATE496054T1 (de) | 2011-02-15 |
| US6855821B2 (en) | 2005-02-15 |
| MXPA05001451A (es) | 2005-09-30 |
| KR20050052461A (ko) | 2005-06-02 |
| EP1534255B1 (en) | 2011-01-19 |
| CA2494183A1 (en) | 2004-04-08 |
| IL166682A0 (en) | 2006-01-15 |
| KR101108115B1 (ko) | 2012-01-31 |
| DE60335805D1 (de) | 2011-03-03 |
| US20040087806A1 (en) | 2004-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2002098865A3 (fr) | Inhibiteurs des phosphodiesterases des nucleotides cycliques, preparation et utilisations de ces inhibiteurs | |
| GEP20074099B (en) | 3-β-D-RIBOFURANO-SYLTHIAZOLO[4,5-d]PYRIDIMINE NUCLEOSIDES AND USES THEREOF | |
| HK1053122A1 (en) | Pyrimidine compounds and their use in the preparation of a triazolo-pyrimidine carba nucleoside | |
| WO2002102313A3 (en) | Pyrimidine inhibitors of phosphodiesterase (pde) 7 | |
| IL166710A0 (en) | Process for the preparation of 4-ÄÄ4-ÄÄ-(2-cyanoethenyl)2,6-dimethylphenylÜaminoÜ-2-pyrimidinylÜaminoÜbenzonitrile | |
| WO2003015798A1 (en) | Novel virus proliferation inhibition/virucidal method and novel pyradine nucleotide/pyradine nucleoside analogue | |
| IL163781A0 (en) | Purine derivatives as kinase inhibitors | |
| IL112539A (en) | Chloropyrimidine intermediates for preparing-2-aminopurine nucleoside analogues and their preparation | |
| NZ527470A (en) | Acylated indanyl amines and their use as pharmaceuticals | |
| MXPA03001431A (es) | Polimeros de un analogo de epotilona. | |
| DE69025529T2 (de) | Weitere antivirale Pyrimidin-Nukleosiden | |
| IL172015A0 (en) | Pyrimidine compounds having phosphonate groups as antiviral nucleotide analogs | |
| PT1280813E (pt) | Analogos de nucleosidos de pirimidina antivirais | |
| HK1078781A1 (en) | Processes for preparing 1,3-dioxolane nucleosides | |
| MXPA03008811A (es) | Procedimiento para la preparacion de 4,6-diaminopirimido (5,4-d) pirimidinas. | |
| AU2003248647A1 (en) | Stereoselective synthesis of 1,2-disubstituted cycloalkyls | |
| AU2003272886A1 (en) | (1,2,4)-TRIAZOLO(1,5-c)PYRIMIDINE DERIVATIVE | |
| WO2003002580A8 (en) | 6-`2-(phosphonomethoxy)alkoxy pyrimidine derivatives having antiviral activity | |
| GB0229081D0 (en) | Multifunctional cationic photoinitiators, their preparation and use | |
| HK1034512A1 (en) | Process for the production of purine derivatives and intermediates therefor | |
| AU8204001A (en) | Process for the preparation of baccatin iii derivatives | |
| EP1613606A4 (en) | PROCESS FOR PREPARING 2,3,5,6-SUBSTITUTED 3H-PYRIMIDIN-4-ONES | |
| AU2003276009A1 (en) | Regulation of human 3', 5' cyclic nucleotide phosphodiesterase pde1c | |
| WO2004039808A3 (en) | Process for the preparation of ganciclovir | |
| WO2004096828A3 (fr) | Nouveau procede et intermediaires de preparation de composes 19-nor-steroïdes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20150806 |