HK1070883A1 - R-(-)-1-2-(7-chlorobenzo-b-thiophen-3-yl-methoxy)-2(2,4-dichlorophenyl)ethyl-1h-imidazole - Google Patents

R-(-)-1-2-(7-chlorobenzo-b-thiophen-3-yl-methoxy)-2(2,4-dichlorophenyl)ethyl-1h-imidazole

Info

Publication number
HK1070883A1
HK1070883A1 HK05100468A HK05100468A HK1070883A1 HK 1070883 A1 HK1070883 A1 HK 1070883A1 HK 05100468 A HK05100468 A HK 05100468A HK 05100468 A HK05100468 A HK 05100468A HK 1070883 A1 HK1070883 A1 HK 1070883A1
Authority
HK
Hong Kong
Prior art keywords
thiophen
imidazole
methoxy
ethyl
chlorobenzo
Prior art date
Application number
HK05100468A
Other languages
English (en)
Inventor
Foguet Rafael
Ramentol Jorge
Guglietta Antonio
Palacin Celia
Anglada Luis
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of HK1070883A1 publication Critical patent/HK1070883A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HK05100468A 2002-02-11 2005-01-18 R-(-)-1-2-(7-chlorobenzo-b-thiophen-3-yl-methoxy)-2(2,4-dichlorophenyl)ethyl-1h-imidazole HK1070883A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200200328A ES2203316B1 (es) 2002-02-11 2002-02-11 R-(-)-1-(2-(7-cloro-benzo(b)tiofen-3-il-metoxi)-2-(2,4-dicloro-fenil)-etil)1h-imidazol.
PCT/EP2003/001089 WO2003068770A1 (en) 2002-02-11 2003-02-04 R- (-) -1- [2- (7-CHLOROBENZO [b] THIOPHEN-3 -YL- METHOXY) -2- (2,4-DICHLOROPHENYL) -ETHYL] -1H-IMIDAZOLE

Publications (1)

Publication Number Publication Date
HK1070883A1 true HK1070883A1 (en) 2005-06-30

Family

ID=27675919

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05100468A HK1070883A1 (en) 2002-02-11 2005-01-18 R-(-)-1-2-(7-chlorobenzo-b-thiophen-3-yl-methoxy)-2(2,4-dichlorophenyl)ethyl-1h-imidazole

Country Status (25)

Country Link
US (1) US7323433B2 (xx)
EP (1) EP1474422B1 (xx)
JP (1) JP5095070B2 (xx)
KR (1) KR100701457B1 (xx)
CN (1) CN1315824C (xx)
AT (1) ATE382618T1 (xx)
AU (1) AU2003205733B8 (xx)
BR (1) BR0307754A (xx)
CA (1) CA2474627C (xx)
CO (1) CO5601026A2 (xx)
DE (1) DE60318395T2 (xx)
DK (1) DK1474422T3 (xx)
ES (1) ES2203316B1 (xx)
HK (1) HK1070883A1 (xx)
IL (1) IL163452A (xx)
MX (1) MXPA04007581A (xx)
NO (1) NO327937B1 (xx)
NZ (1) NZ534464A (xx)
PL (1) PL211168B1 (xx)
PT (1) PT1474422E (xx)
RU (1) RU2276152C1 (xx)
TN (1) TNSN04140A1 (xx)
UA (1) UA78010C2 (xx)
WO (1) WO2003068770A1 (xx)
ZA (1) ZA200405941B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2249992B1 (es) 2004-09-13 2007-03-01 Ferrer Internacional, S.A. Un procedimiento para fabricar compuestos enantiomericos del imidazol.
ES2249991B1 (es) * 2004-09-13 2007-03-01 Ferrer Internacional, S.A. Procedimiento de fabricacion de compuestos imidazolicos, sus sales y sus pseudopolimorfos.
EP1698336A1 (en) * 2005-03-01 2006-09-06 Ferrer Internacional, S.A. Antifungal compositions comprising Sertaconazole and either Hydrocortisone or an antibacterial agent
RU2477280C1 (ru) * 2008-12-09 2013-03-10 Феррер Интернасионал С.А. Полиморфная модификация ii противогрибкового соединения, способ ее получения (варианты), фармацевтическая и сельскохозяйственная композиции на ее основе, способ лечения или профилактики заболеваний, вызванных грибками и/или дрожжами
EP2436374A1 (en) * 2010-09-30 2012-04-04 Ferrer Internacional, S.A. Ovule for vaginal administration of arasertaconazole
EP2551351A1 (en) 2011-07-29 2013-01-30 Interquim, S.A. Process for production of optically active (R)-(-)-1-(2,4-dichloro-phenyl)-2-imidazole-1-yl-ethanol
CN102440947B (zh) * 2011-11-15 2012-12-26 海南海神同洲制药有限公司 硝酸舍他康唑乳膏剂
KR101717968B1 (ko) 2016-07-18 2017-03-20 씨앤아이 주식회사 스마트폰 결합 모듈
CN113480517B (zh) * 2021-07-30 2022-09-09 海南海神同洲制药有限公司 3-溴甲基-7-氯苯并[b]噻吩的合成方法
CN113735843B (zh) * 2021-09-07 2023-05-26 海南海神同洲制药有限公司 一种低熔点硝酸舍他康唑的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1250586A (en) * 1984-02-02 1989-02-28 Manuel Raga 1h-imidazole derivatives and process for their production
US5135943A (en) * 1984-02-02 1992-08-04 Ferrer Internacional S.A. 1H-imidazole derivative compounds and pharmaceutical compositions containing the same
US5087620A (en) * 1990-05-17 1992-02-11 Bristol-Myers Squibb Co. Controlled dermal penetration enhancement using imidazoles
AU691234B2 (en) * 1995-01-04 1998-05-14 Ferrer Internacional, S.A. Process for preparing polymorphs B and C of 1- 2,4-dichloro -beta- (7-chlorobenzo b thien-3-yl)methoxy phenethyl imidazole mononitrate

Also Published As

Publication number Publication date
ES2203316A1 (es) 2004-04-01
UA78010C2 (uk) 2007-02-15
CN1315824C (zh) 2007-05-16
BR0307754A (pt) 2004-12-07
US20050065201A1 (en) 2005-03-24
RU2276152C1 (ru) 2006-05-10
PL370251A1 (en) 2005-05-16
PL211168B1 (pl) 2012-04-30
EP1474422B1 (en) 2008-01-02
US7323433B2 (en) 2008-01-29
KR20040079996A (ko) 2004-09-16
MXPA04007581A (es) 2004-11-10
PT1474422E (pt) 2008-02-28
RU2004127573A (ru) 2006-02-10
AU2003205733B8 (en) 2008-09-04
CO5601026A2 (es) 2006-01-31
ZA200405941B (en) 2006-07-26
ES2203316B1 (es) 2005-03-01
WO2003068770A1 (en) 2003-08-21
NO327937B1 (no) 2009-10-26
DE60318395T2 (de) 2009-01-02
ATE382618T1 (de) 2008-01-15
TNSN04140A1 (en) 2007-03-12
CA2474627A1 (en) 2003-08-21
CN1630654A (zh) 2005-06-22
EP1474422A1 (en) 2004-11-10
NO20043377L (no) 2004-08-13
KR100701457B1 (ko) 2007-03-29
DK1474422T3 (da) 2008-05-13
DE60318395D1 (de) 2008-02-14
NZ534464A (en) 2006-02-24
JP2005524639A (ja) 2005-08-18
AU2003205733B2 (en) 2008-08-14
JP5095070B2 (ja) 2012-12-12
AU2003205733A1 (en) 2003-09-04
CA2474627C (en) 2009-09-22
IL163452A (en) 2011-11-30

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20170204