HK1070573A1 - Nociceptin compounds - Google Patents

Nociceptin compounds

Info

Publication number
HK1070573A1
HK1070573A1 HK05103227.4A HK05103227A HK1070573A1 HK 1070573 A1 HK1070573 A1 HK 1070573A1 HK 05103227 A HK05103227 A HK 05103227A HK 1070573 A1 HK1070573 A1 HK 1070573A1
Authority
HK
Hong Kong
Prior art keywords
nociceptin
compounds
nociceptin compounds
Prior art date
Application number
HK05103227.4A
Other languages
English (en)
Inventor
Richard R Goehring
Zhengming Chen
Donald Kyle
Sam Victory
Parviz Gharagozloo
John Whitehead
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of HK1070573A1 publication Critical patent/HK1070573A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK05103227.4A 2001-04-18 2005-04-15 Nociceptin compounds HK1070573A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28467601P 2001-04-18 2001-04-18
US28467401P 2001-04-18 2001-04-18
PCT/US2002/012356 WO2002085291A2 (en) 2001-04-18 2002-04-18 Nociceptin analogs

Publications (1)

Publication Number Publication Date
HK1070573A1 true HK1070573A1 (en) 2005-06-24

Family

ID=26962736

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05103227.4A HK1070573A1 (en) 2001-04-18 2005-04-15 Nociceptin compounds

Country Status (14)

Country Link
US (3) US6861421B2 (zh)
EP (2) EP1997818A3 (zh)
JP (2) JP4380992B2 (zh)
KR (3) KR100729242B1 (zh)
CN (1) CN100441182C (zh)
AU (2) AU2002303406B2 (zh)
BR (1) BR0209128A (zh)
CA (1) CA2444108C (zh)
HK (1) HK1070573A1 (zh)
HU (1) HUP0402510A3 (zh)
IL (2) IL158486A0 (zh)
MX (1) MXPA03009602A (zh)
RU (1) RU2268883C2 (zh)
WO (1) WO2002085291A2 (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1485353B1 (en) * 2002-03-13 2011-08-24 Janssen Pharmaceutica NV New inhibitors of histone deacetylase
ES2392340T3 (es) 2002-03-29 2012-12-07 Mitsubishi Tanabe Pharma Corporation Remedio para los trastornos del sueño
US7718652B2 (en) 2006-12-12 2010-05-18 Wyeth Llc Substituted benzothiadiazinedioxide derivatives and methods of their use
CL2007003590A1 (es) * 2006-12-12 2008-02-29 Wyeth Corp Compuestos derivados de aril sulfamida; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso en prevencion y tratamiento de sintomas vasomotrices, disfuncion sexual, transtornos gastrointestinales, transt
ES2353448T3 (es) * 2007-01-16 2011-03-02 Purdue Pharma L.P. Piperidinas heterocíclico-sustituidas como ligandos de orl-1.
NZ582940A (en) 2007-08-31 2013-01-25 Purdue Pharma Lp Substituted-quinoxaline-type piperidine compounds and the uses thereof
BRPI0911031B8 (pt) 2008-07-21 2021-05-25 Purdue Pharma Lp compostos de piperidina ligada do tipo quinoxalina substituídos e os usos destes
ES2613631T3 (es) 2010-12-22 2017-05-25 Purdue Pharma L.P. Compuestos de piperidina de tipo quinoxalina sustituidos con fósforo y usos de los mismos
US9951038B2 (en) 2012-12-27 2018-04-24 Purdue Pharma L.P. Quinazolin-4(3H)-one-type piperidine compounds and uses thereof
WO2014102594A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
US9963458B2 (en) 2012-12-27 2018-05-08 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
WO2014102590A1 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Substituted piperidin-4-amino-type compounds and uses thereof
CA2896871A1 (en) * 2012-12-31 2014-07-03 Kerry L. Spear Heterocyclic compounds and methods of use thereof
RS60315B1 (sr) 2016-01-13 2020-07-31 Gruenenthal Gmbh Derivati 3-((hetero-)aril)-alkil-8-amino-2-okso-1,3-diaza-spiro-[4.5]-dekana
SI3402785T1 (sl) 2016-01-13 2020-07-31 Gruenenthal Gmbh Derivati 3-(karboksimetil)-8-amino-2-okso-1,3-diaza-spiro-(4.5)-dekana
CA3011182A1 (en) 2016-01-13 2017-07-20 Grunenthal Gmbh 8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives
AR107361A1 (es) 2016-01-13 2018-04-25 Gruenenthal Gmbh Derivados de 3-(carboxietil)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano
BR112018014305B1 (pt) 2016-01-13 2023-10-17 Grünenthal GmbH Derivados de 3-((hetero-)aril)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3161645A (en) 1962-12-18 1964-12-15 Res Lab Dr C Janssen N V 1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compounds
US3318900A (en) 1964-05-06 1967-05-09 Janssen Pharmaceutica Nv Derivatives of benzimidazolinyl piperidine
US3325499A (en) 1964-11-02 1967-06-13 Mcneilab Inc 1-(1-hydrocarbyl-4-piperdyl)-2-indolinone
DE2609645A1 (de) 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen
EP0029707B1 (en) * 1979-11-21 1984-02-01 Kyowa Hakko Kogyo Co., Ltd Novel piperidine derivatives, method for the preparation thereof and pharmaceutical compositions containing them
US4344945A (en) * 1980-03-10 1982-08-17 Kyowa Hakko Kogyo Co., Ltd. Piperidine derivatives
US4329353A (en) 1980-10-22 1982-05-11 Janssen Pharmaceutica, N.V. 1-(4-Aryl-cyclohexyl)piperidine derivatives, method of use thereof and pharmaceutical compositions thereof
US4410528A (en) 1980-05-16 1983-10-18 Kyowa Hakko Kogyo Co., Ltd. Hypotensive piperidine derivatives
JPS5759889A (en) * 1980-09-30 1982-04-10 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative
JPS58180481A (ja) 1982-04-15 1983-10-21 Kyowa Hakko Kogyo Co Ltd 新規なピペリジン誘導体
JPS60120872A (ja) 1983-12-01 1985-06-28 Kyowa Hakko Kogyo Co Ltd 新規なヘテロ環状化合物及び強心剤
DE69009785T2 (de) * 1989-02-10 1994-11-03 Otsuka Pharma Co Ltd Carbostyrilderivate.
WO1995019773A1 (en) * 1992-10-07 1995-07-27 Merck & Co., Inc. Carbostyril oxytocin receptor antagonists
WO1995002405A1 (en) * 1993-07-16 1995-01-26 Merck & Co., Inc. Benzoxazinone and benzopyrimidinone piperidinyl tocolytic oxytocin receptor antagonists
WO1995028397A1 (en) 1994-04-14 1995-10-26 Merck & Co., Inc. Alpha1c adrenergic receptor antagonists
FR2722190B1 (fr) 1994-07-05 1996-10-04 Sanofi Sa Derives de 1-benzyl-1,3-dihydro-2h-benzimidazol-2-one, leur preparation, les compositions pharmaceutique en contenant
US5767118A (en) * 1994-10-26 1998-06-16 Merck & Co., Inc. 4-Heterocyclic peperidines promote release of growth hormone
US5574044A (en) 1994-10-27 1996-11-12 Merck & Co., Inc. Muscarine antagonists
US6136839A (en) 1995-06-12 2000-10-24 G. D. Searle & Co. Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor
EP0974583B1 (en) 1995-09-13 2002-05-29 Kyowa Hakko Kogyo Co., Ltd. Phenylpiperidine derivatives
EP0898568B1 (en) 1996-04-19 2006-10-04 Neurosearch A/S 1-(4-piperidyl)-benzimidazoles having neurotrophic activity
US6063796A (en) * 1997-04-04 2000-05-16 Merck & Co., Inc. Somatostatin agonists
WO1998054168A1 (fr) 1997-05-30 1998-12-03 Banyu Pharmaceutical Co., Ltd. Derives de 2-0xoimidazole
JPH10330377A (ja) * 1997-06-02 1998-12-15 Kyowa Hakko Kogyo Co Ltd ピペリジン誘導体
US6166037A (en) 1997-08-28 2000-12-26 Merck & Co., Inc. Pyrrolidine and piperidine modulators of chemokine receptor activity
SI0921125T1 (en) 1997-12-05 2002-04-30 F. Hoffmann-La Roche Ag 1,3,8-Triazaspiro(4,5)decan-4-on derivatives
US6166209A (en) 1997-12-11 2000-12-26 Hoffmann-La Roche Inc. Piperidine derivatives
PL342046A1 (en) 1998-01-19 2001-05-21 Pfizer 4-(2-keto-1-benzimidazolinyl)piperidine compounds as agonists of orl1 receptor
CN1301154A (zh) 1998-03-26 2001-06-27 日本烟草产业株式会社 酰胺衍生物和nociceptin拮抗剂
AU3809999A (en) 1998-05-18 1999-12-06 Novo Nordisk A/S Novel 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes
US6262066B1 (en) 1998-07-27 2001-07-17 Schering Corporation High affinity ligands for nociceptin receptor ORL-1
ID29137A (id) 1998-07-27 2001-08-02 Schering Corp Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
MA26659A1 (fr) 1998-08-06 2004-12-20 Pfizer Dérivés de benzimidazole nouveaux, compositions pharmaceutiques les contenant et procédé pour leur préparation.
JP2001044213A (ja) * 1999-07-30 2001-02-16 Hitachi Cable Ltd ヘテロバイポーラトランジスタ用エピタキシャルウエハ
SE9904652D0 (sv) * 1999-12-17 1999-12-17 Astra Pharma Prod Novel Compounds
DE60112725T2 (de) 2000-02-18 2006-06-01 Meiji Seika Kaisha Ltd. Phenoxyalkylaminderivate als agonisten des opioid-delta rezeptors
PL213103B1 (pl) * 2000-08-14 2013-01-31 Ortho Mcneil Pharm Inc Podstawiona pochodna pirazolu, jej zastosowanie i zawierajaca ja kompozycja farmaceutyczna
HUP0302475A2 (hu) * 2000-09-06 2003-11-28 Ortho-Mcneil Pharmaceutical, Inc. Eljárás allergia kezelésére szubsztituált pirazolok alkalmazásával
JP2007009500A (ja) * 2005-06-30 2007-01-18 Nissei Ltd パズル循環式駐車設備の運転方法

Also Published As

Publication number Publication date
CN100441182C (zh) 2008-12-10
EP1379252A2 (en) 2004-01-14
IL158486A0 (en) 2004-05-12
KR20060129103A (ko) 2006-12-14
US20090253727A1 (en) 2009-10-08
AU2006202794A1 (en) 2006-07-20
KR100729242B1 (ko) 2007-06-15
KR100855204B1 (ko) 2008-09-01
EP1997818A2 (en) 2008-12-03
JP2009280603A (ja) 2009-12-03
EP1997818A3 (en) 2009-04-08
JP2005506302A (ja) 2005-03-03
RU2003133454A (ru) 2005-05-27
JP4380992B2 (ja) 2009-12-09
KR20030096326A (ko) 2003-12-24
EP1379252A4 (en) 2005-11-02
US7563809B2 (en) 2009-07-21
BR0209128A (pt) 2005-11-01
WO2002085291A3 (en) 2003-02-20
HUP0402510A3 (en) 2012-08-28
CA2444108A1 (en) 2002-10-31
US20050148580A1 (en) 2005-07-07
WO2002085291A2 (en) 2002-10-31
KR20050118315A (ko) 2005-12-16
MXPA03009602A (es) 2004-04-02
AU2002303406B2 (en) 2006-03-30
KR100722207B1 (ko) 2007-05-29
CA2444108C (en) 2012-07-24
US20030013874A1 (en) 2003-01-16
CN1568188A (zh) 2005-01-19
RU2268883C2 (ru) 2006-01-27
US6861421B2 (en) 2005-03-01
IL158486A (en) 2010-11-30
HUP0402510A2 (hu) 2005-04-28

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20140418