HK1069974A1 - Pharmaceutical compositions comprising metformine and glibenclamide for the treatment of type-II diabetes mellitus - Google Patents

Pharmaceutical compositions comprising metformine and glibenclamide for the treatment of type-II diabetes mellitus

Info

Publication number
HK1069974A1
HK1069974A1 HK05102373A HK05102373A HK1069974A1 HK 1069974 A1 HK1069974 A1 HK 1069974A1 HK 05102373 A HK05102373 A HK 05102373A HK 05102373 A HK05102373 A HK 05102373A HK 1069974 A1 HK1069974 A1 HK 1069974A1
Authority
HK
Hong Kong
Prior art keywords
metformine
glibenclamide
treatment
type
pharmaceutical compositions
Prior art date
Application number
HK05102373A
Other languages
English (en)
Inventor
Tosetti Alessandro
Guiducci Mauro
Viti Giovanni
Original Assignee
Menarini Int Operations Lu Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11442301&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1069974(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Menarini Int Operations Lu Sa filed Critical Menarini Int Operations Lu Sa
Publication of HK1069974A1 publication Critical patent/HK1069974A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK05102373A 2001-11-29 2005-03-18 Pharmaceutical compositions comprising metformine and glibenclamide for the treatment of type-II diabetes mellitus HK1069974A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001FI000230A ITFI20010230A1 (it) 2001-11-29 2001-11-29 Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii
PCT/EP2002/013497 WO2003045355A1 (en) 2001-11-29 2002-11-29 Pharmaceutical compositions comprising metformine and glibenclamide for the treatment of type-ii diabetes mellitus

Publications (1)

Publication Number Publication Date
HK1069974A1 true HK1069974A1 (en) 2005-06-10

Family

ID=11442301

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05102373A HK1069974A1 (en) 2001-11-29 2005-03-18 Pharmaceutical compositions comprising metformine and glibenclamide for the treatment of type-II diabetes mellitus

Country Status (40)

Country Link
US (1) US20050053661A1 (uk)
EP (1) EP1458364B1 (uk)
JP (1) JP4474162B2 (uk)
KR (1) KR20040079898A (uk)
CN (1) CN1596103B (uk)
AR (1) AR037407A1 (uk)
AT (1) ATE387190T1 (uk)
AU (1) AU2002358061B2 (uk)
BR (1) BR0214403A (uk)
CA (1) CA2466677A1 (uk)
CO (1) CO5590906A2 (uk)
CY (1) CY1107966T1 (uk)
DE (1) DE60225331T2 (uk)
DK (1) DK1458364T3 (uk)
EA (1) EA006766B1 (uk)
EG (1) EG24124A (uk)
ES (1) ES2302862T3 (uk)
HK (1) HK1069974A1 (uk)
HN (1) HN2002000341A (uk)
HR (1) HRP20040501A2 (uk)
HU (1) HUP0402154A3 (uk)
IL (1) IL162143A0 (uk)
IT (1) ITFI20010230A1 (uk)
MA (1) MA27087A1 (uk)
MX (1) MXPA04004974A (uk)
MY (1) MY141243A (uk)
NO (1) NO20042713L (uk)
NZ (1) NZ533779A (uk)
PA (1) PA8559801A1 (uk)
PE (1) PE20030580A1 (uk)
PL (1) PL206016B1 (uk)
PT (1) PT1458364E (uk)
RS (1) RS50937B (uk)
SI (1) SI1458364T1 (uk)
SV (1) SV2004001415A (uk)
TN (1) TNSN04095A1 (uk)
UA (1) UA81615C2 (uk)
UY (1) UY27549A1 (uk)
WO (1) WO2003045355A1 (uk)
ZA (1) ZA200404880B (uk)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1349531A1 (en) * 2001-01-12 2003-10-08 Sun Pharmaceuticals Industries Ltd. Spaced drug delivery system
EP1515701B1 (en) 2002-06-17 2014-09-17 Inventia Healthcare Private Limited Process for the manufacture of multilayer tablet compositions comprising thiazolidinedione and biguanide
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en) 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
EP2316456B1 (en) 2003-04-29 2017-06-14 Orexigen Therapeutics, Inc. Compositions for affecting weight loss comprising an opioid antagonist and bupropion
UY29445A1 (es) * 2005-03-30 2006-10-02 Generex Pharm Inc Composiciones para la transmisión transmucosa oral de la metformina
TWI471145B (zh) * 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
KR101479324B1 (ko) * 2006-11-09 2015-01-05 오렉시젠 세러퓨틱스 인크. 신속하게 용해되는 중간층을 포함하는 층상의 약제학적 제형
ITMI20062254A1 (it) * 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
CA2725930A1 (en) 2008-05-30 2009-12-30 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
CA2638240C (en) 2008-08-29 2010-02-02 Alexander Macgregor Method of treating dysglycemia and glucose excursions
US9248123B2 (en) 2010-01-11 2016-02-02 Orexigen Therapeutics, Inc. Methods of providing weight loss therapy in patients with major depression
RU2483717C2 (ru) * 2010-11-22 2013-06-10 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Фармацевтическая композиция для лечения диабета (варианты)
US9572784B2 (en) 2011-01-07 2017-02-21 Elcelyx Therapeutics, Inc. Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
MX2013007884A (es) 2011-01-07 2013-09-13 Elcelyx Therapeutics Inc Terapias a base de ligando del receptor quimiosensorial.
US9480663B2 (en) 2011-01-07 2016-11-01 Elcelyx Therapeutics, Inc. Biguanide compositions and methods of treating metabolic disorders
US11974971B2 (en) 2011-01-07 2024-05-07 Anji Pharmaceuticals Inc. Compositions and methods for treating metabolic disorders
US11759441B2 (en) 2011-01-07 2023-09-19 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
US9211263B2 (en) 2012-01-06 2015-12-15 Elcelyx Therapeutics, Inc. Compositions and methods of treating metabolic disorders
US8796338B2 (en) 2011-01-07 2014-08-05 Elcelyx Therapeutics, Inc Biguanide compositions and methods of treating metabolic disorders
CN110693867A (zh) 2012-01-06 2020-01-17 埃尔舍利克斯治疗公司 用于治疗代谢性病症的组合物和方法
AU2012363873B2 (en) 2012-01-06 2017-11-23 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
AU2013271622B2 (en) 2012-06-06 2018-03-01 Nalpropion Pharmaceuticals Llc Methods of treating overweight and obesity
WO2016076280A1 (ja) 2014-11-11 2016-05-19 塩野義製薬株式会社 光に対して不安定な薬物を含有する多層錠剤
KR101750690B1 (ko) * 2015-10-28 2017-06-27 주식회사 종근당 메트포르민 및 로베글리타존을 포함하는 약제학적 조성물
CN105596339A (zh) * 2015-12-23 2016-05-25 青岛海之源智能技术有限公司 一种二甲双胍阿昔莫司复方组合物及制备方法
CN110128305A (zh) * 2019-05-10 2019-08-16 天津大学 二甲双胍-甲苯磺丁脲新盐型、其制备方法及医药用途
JP2021120357A (ja) * 2020-01-30 2021-08-19 サンノーバ株式会社 錠剤
GB2599950A (en) * 2020-10-16 2022-04-20 Zentiva Ks Pharmaceutical compositions with low amounts of nitrosamine impurities and methods for producing the same
CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2347531A1 (de) * 1973-09-21 1975-04-30 Hoechst Ag Arzneizubereitungen zur oralen diabetes-behandlung
IT1276130B1 (it) * 1995-11-14 1997-10-27 Gentili Ist Spa Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo
EA003101B1 (ru) * 1998-03-19 2002-12-26 Бристол-Майерз Сквибб Компани Двухфазная система доставки с регулируемым высвобождением для фармацевтических средств с высокой растворимостью и способ лечения диабета с помощью этой системы
ATE250418T1 (de) * 1998-07-15 2003-10-15 Merck Sante Sas Tabletten enthaltend eine kombination von glibenclamid und metformin
US6780432B1 (en) * 2000-05-01 2004-08-24 Aeropharm Technology, Inc. Core formulation
EP1349531A1 (en) * 2001-01-12 2003-10-08 Sun Pharmaceuticals Industries Ltd. Spaced drug delivery system

Also Published As

Publication number Publication date
SV2004001415A (es) 2004-05-07
ITFI20010230A1 (it) 2003-05-29
PA8559801A1 (es) 2003-06-30
EA006766B1 (ru) 2006-04-28
HRP20040501A2 (en) 2004-12-31
CY1107966T1 (el) 2013-09-04
UA81615C2 (uk) 2008-01-25
CN1596103B (zh) 2010-06-16
MA27087A1 (fr) 2004-12-20
CO5590906A2 (es) 2005-12-30
KR20040079898A (ko) 2004-09-16
ZA200404880B (en) 2005-07-29
EP1458364A1 (en) 2004-09-22
HN2002000341A (es) 2009-12-07
BR0214403A (pt) 2004-10-19
US20050053661A1 (en) 2005-03-10
IL162143A0 (en) 2005-11-20
ATE387190T1 (de) 2008-03-15
PL369851A1 (en) 2005-05-02
HUP0402154A3 (en) 2008-04-28
RS50937B (sr) 2010-08-31
EG24124A (en) 2008-07-07
AU2002358061A1 (en) 2003-06-10
UY27549A1 (es) 2003-06-30
EP1458364B1 (en) 2008-02-27
NZ533779A (en) 2007-02-23
AU2002358061B2 (en) 2007-01-11
DE60225331T2 (de) 2009-02-26
WO2003045355A1 (en) 2003-06-05
SI1458364T1 (sl) 2008-08-31
CN1596103A (zh) 2005-03-16
RS47304A (en) 2006-10-27
AR037407A1 (es) 2004-11-10
HUP0402154A2 (hu) 2005-02-28
DK1458364T3 (da) 2008-06-23
EA200400664A1 (ru) 2004-10-28
JP2005518360A (ja) 2005-06-23
TNSN04095A1 (en) 2006-06-01
MY141243A (en) 2010-03-31
PE20030580A1 (es) 2003-09-05
DE60225331D1 (de) 2008-04-10
ES2302862T3 (es) 2008-08-01
JP4474162B2 (ja) 2010-06-02
MXPA04004974A (es) 2004-08-11
PL206016B1 (pl) 2010-06-30
CA2466677A1 (en) 2003-06-05
PT1458364E (pt) 2008-05-26
NO20042713L (no) 2004-07-16

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20111129