HK1066488A1 - Method of encapsulating an active substance - Google Patents

Method of encapsulating an active substance

Info

Publication number
HK1066488A1
HK1066488A1 HK04109553A HK04109553A HK1066488A1 HK 1066488 A1 HK1066488 A1 HK 1066488A1 HK 04109553 A HK04109553 A HK 04109553A HK 04109553 A HK04109553 A HK 04109553A HK 1066488 A1 HK1066488 A1 HK 1066488A1
Authority
HK
Hong Kong
Prior art keywords
active substance
inter
coating
product
encapsulating
Prior art date
Application number
HK04109553A
Other languages
English (en)
Inventor
Francis Sean Moolman
Heidi Rolfes
Thilo Lothar Van Der Merwe
Original Assignee
Csir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25589180&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1066488(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Csir filed Critical Csir
Publication of HK1066488A1 publication Critical patent/HK1066488A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Paints Or Removers (AREA)
HK04109553A 2001-05-30 2004-12-02 Method of encapsulating an active substance HK1066488A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA200104451 2001-05-30
PCT/IB2002/001853 WO2003013478A2 (fr) 2001-05-30 2002-05-28 Procede d'encapsulation d'une substance active

Publications (1)

Publication Number Publication Date
HK1066488A1 true HK1066488A1 (en) 2005-03-24

Family

ID=25589180

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04109553A HK1066488A1 (en) 2001-05-30 2004-12-02 Method of encapsulating an active substance

Country Status (21)

Country Link
US (1) US7641917B2 (fr)
EP (1) EP1401404B1 (fr)
JP (1) JP4313196B2 (fr)
CN (1) CN1255099C (fr)
AT (1) ATE392203T1 (fr)
AU (1) AU2002310567B2 (fr)
BR (1) BR0210000A (fr)
CA (1) CA2455208C (fr)
CH (1) CH695418A5 (fr)
CY (1) CY1108199T1 (fr)
DE (2) DE10296849T5 (fr)
DK (1) DK1401404T3 (fr)
ES (1) ES2305250T3 (fr)
FR (1) FR2825292B1 (fr)
GB (1) GB2392619B (fr)
HK (1) HK1066488A1 (fr)
IT (1) ITMI20021169A1 (fr)
NL (1) NL1020706C2 (fr)
PT (1) PT1401404E (fr)
WO (1) WO2003013478A2 (fr)
ZA (1) ZA200309983B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2305250T3 (es) 2001-05-30 2008-11-01 Csir Procedimiento de encapsulacion de una sustancia activa.
US7903319B2 (en) * 2006-07-11 2011-03-08 E Ink Corporation Electrophoretic medium and display with improved image stability
US20080082764A1 (en) * 2006-10-03 2008-04-03 Yi Feng Jang Memory accessing system and method
GB0812742D0 (en) * 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Process
GB201317756D0 (en) 2013-10-08 2013-11-20 Critical Pharmaceuticals Ltd New process
DE102018210030A1 (de) * 2018-06-20 2019-12-24 Thyssenkrupp Ag Verwendung und Recyclieren von überkritischen CO2 als Lösungsmittel für PLA und weitere biologisch abbaubaren Polymere in das Beschichtungsverfahren für Düngemittel
IT201800007993A1 (it) * 2018-08-09 2020-02-09 Greenbone Ortho Srl Impianto finalizzato alla trasformazione chimica di materiali nello stato 3d
CN112812355B (zh) * 2020-12-31 2022-09-23 厦门天生爱科技有限公司 一种具有缓释挥发性中草药有效成分的功能高分子发泡材料、制备方法和用途

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8500121D0 (en) 1985-01-03 1985-02-13 Connaught Lab Microencapsulation of living cells
DE3787533T2 (de) * 1987-12-21 1994-01-20 Union Carbide Corp Verwendung von superkritischen Flüssigkeiten als Verdünner beim Aufsprühen von Überzügen.
EP0706821A1 (fr) * 1994-10-06 1996-04-17 Centre De Microencapsulation Procédé pour l'enrobage de particules
US5939485A (en) * 1995-06-19 1999-08-17 Medlogic Global Corporation Responsive polymer networks and methods of their use
US6221399B1 (en) * 1995-08-17 2001-04-24 Csir Method of making controlled release particles of complexed polymers
FR2753639B1 (fr) * 1996-09-25 1998-12-11 Procede de preparation de microcapsules de matieres actives enrobees par un polymere et nouvelles microcapsules notamment obtenues selon le procede
US5766637A (en) * 1996-10-08 1998-06-16 University Of Delaware Microencapsulation process using supercritical fluids
AU735334B2 (en) * 1997-02-17 2001-07-05 Doppel Co., Ltd. Method for manufacturing artificial stone
GB9800936D0 (en) 1997-05-10 1998-03-11 Univ Nottingham Biofunctional polymers
DE69841422D1 (de) 1997-10-15 2010-02-11 Univ South Florida Beschichtung von partikelmaterial mittels superkritischer flüssigkeit
IT1296464B1 (it) 1997-11-19 1999-06-25 Vectorpharma Int Composizioni farmaceutiche in forma di polveri di polimeri reticolati caricati con farmaci e relativo processo di preparazione mediante
GB9814619D0 (en) 1998-07-06 1998-09-02 Cole Polytechnique Fudurale De Materials and methods relating to encapsulation
US6340722B1 (en) 1998-09-04 2002-01-22 The University Of Akron Polymerization, compatibilized blending, and particle size control of powder coatings in a supercritical fluid
US6350786B1 (en) * 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers
GB9920558D0 (en) 1999-08-31 1999-11-03 Bradford Particle Design Ltd Methods for particle formation and their products
US6372259B1 (en) * 1999-11-10 2002-04-16 University Of Iowa Research Foundation Palatable, sustained release drug granules
WO2002020624A1 (fr) 2000-09-08 2002-03-14 Ferro Corporation Medicaments a liberation prolongee prepares par des techniques de traitement par fluides supercritiques
US6521258B1 (en) * 2000-09-08 2003-02-18 Ferro Corporation Polymer matrices prepared by supercritical fluid processing techniques
ES2305250T3 (es) 2001-05-30 2008-11-01 Csir Procedimiento de encapsulacion de una sustancia activa.

Also Published As

Publication number Publication date
CA2455208C (fr) 2009-02-03
GB2392619B (en) 2004-10-20
ITMI20021169A0 (it) 2002-05-30
NL1020706C2 (nl) 2003-04-28
US20050112205A1 (en) 2005-05-26
DE10296849T5 (de) 2004-04-29
PT1401404E (pt) 2008-07-23
CN1512877A (zh) 2004-07-14
CH695418A5 (de) 2006-05-15
JP2005502642A (ja) 2005-01-27
NL1020706A1 (nl) 2002-12-03
BR0210000A (pt) 2004-05-04
WO2003013478A3 (fr) 2003-05-30
DK1401404T3 (da) 2008-08-11
FR2825292B1 (fr) 2006-06-09
CY1108199T1 (el) 2014-02-12
CN1255099C (zh) 2006-05-10
GB2392619A (en) 2004-03-10
DE60226140T2 (de) 2009-05-07
GB0327381D0 (en) 2003-12-31
ITMI20021169A1 (it) 2003-12-01
WO2003013478A2 (fr) 2003-02-20
CA2455208A1 (fr) 2003-02-20
JP4313196B2 (ja) 2009-08-12
EP1401404B1 (fr) 2008-04-16
US7641917B2 (en) 2010-01-05
ES2305250T3 (es) 2008-11-01
FR2825292A1 (fr) 2002-12-06
ZA200309983B (en) 2005-01-26
AU2002310567B2 (en) 2005-10-20
DE60226140D1 (de) 2008-05-29
WO2003013478A8 (fr) 2003-04-03
EP1401404A2 (fr) 2004-03-31
ATE392203T1 (de) 2008-05-15

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20180528