NL1020706A1 - Werkwijze voor het inkapselen van een actieve substantie. - Google Patents

Werkwijze voor het inkapselen van een actieve substantie.

Info

Publication number
NL1020706A1
NL1020706A1 NL1020706A NL1020706A NL1020706A1 NL 1020706 A1 NL1020706 A1 NL 1020706A1 NL 1020706 A NL1020706 A NL 1020706A NL 1020706 A NL1020706 A NL 1020706A NL 1020706 A1 NL1020706 A1 NL 1020706A1
Authority
NL
Netherlands
Prior art keywords
active substance
inter
coating
product
encapsulating
Prior art date
Application number
NL1020706A
Other languages
English (en)
Other versions
NL1020706C2 (nl
Inventor
Francis Sean Moolman
Heidi Rolfes
Thilo Lothar Van Der Merwe
Original Assignee
Csir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25589180&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL1020706(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Csir filed Critical Csir
Publication of NL1020706A1 publication Critical patent/NL1020706A1/nl
Application granted granted Critical
Publication of NL1020706C2 publication Critical patent/NL1020706C2/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Medicinal Preparation (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Paints Or Removers (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NL1020706A 2001-05-30 2002-05-29 Werkwijze voor het inkapselen van een actieve substantie. NL1020706C2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA200104451 2001-05-30
ZA200104451 2001-05-30

Publications (2)

Publication Number Publication Date
NL1020706A1 true NL1020706A1 (nl) 2002-12-03
NL1020706C2 NL1020706C2 (nl) 2003-04-28

Family

ID=25589180

Family Applications (1)

Application Number Title Priority Date Filing Date
NL1020706A NL1020706C2 (nl) 2001-05-30 2002-05-29 Werkwijze voor het inkapselen van een actieve substantie.

Country Status (21)

Country Link
US (1) US7641917B2 (nl)
EP (1) EP1401404B1 (nl)
JP (1) JP4313196B2 (nl)
CN (1) CN1255099C (nl)
AT (1) ATE392203T1 (nl)
AU (1) AU2002310567B2 (nl)
BR (1) BR0210000A (nl)
CA (1) CA2455208C (nl)
CH (1) CH695418A5 (nl)
CY (1) CY1108199T1 (nl)
DE (2) DE10296849T5 (nl)
DK (1) DK1401404T3 (nl)
ES (1) ES2305250T3 (nl)
FR (1) FR2825292B1 (nl)
GB (1) GB2392619B (nl)
HK (1) HK1066488A1 (nl)
IT (1) ITMI20021169A1 (nl)
NL (1) NL1020706C2 (nl)
PT (1) PT1401404E (nl)
WO (1) WO2003013478A2 (nl)
ZA (1) ZA200309983B (nl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1401404B1 (en) 2001-05-30 2008-04-16 Csir Method of encapsulating an active substance
US7903319B2 (en) * 2006-07-11 2011-03-08 E Ink Corporation Electrophoretic medium and display with improved image stability
US20080082764A1 (en) * 2006-10-03 2008-04-03 Yi Feng Jang Memory accessing system and method
GB0812742D0 (en) 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Process
GB201317756D0 (en) 2013-10-08 2013-11-20 Critical Pharmaceuticals Ltd New process
DE102018210030A1 (de) * 2018-06-20 2019-12-24 Thyssenkrupp Ag Verwendung und Recyclieren von überkritischen CO2 als Lösungsmittel für PLA und weitere biologisch abbaubaren Polymere in das Beschichtungsverfahren für Düngemittel
IT201800007993A1 (it) * 2018-08-09 2020-02-09 Greenbone Ortho Srl Impianto finalizzato alla trasformazione chimica di materiali nello stato 3d
CN112812355B (zh) * 2020-12-31 2022-09-23 厦门天生爱科技有限公司 一种具有缓释挥发性中草药有效成分的功能高分子发泡材料、制备方法和用途

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8500121D0 (en) 1985-01-03 1985-02-13 Connaught Lab Microencapsulation of living cells
EP0321607B1 (en) * 1987-12-21 1993-09-22 Union Carbide Corporation Supercritical fluids as diluents in liquid spray application of coatings
EP0706821A1 (en) * 1994-10-06 1996-04-17 Centre De Microencapsulation Method of coating particles
US5939485A (en) * 1995-06-19 1999-08-17 Medlogic Global Corporation Responsive polymer networks and methods of their use
WO1997006787A2 (en) * 1995-08-17 1997-02-27 Dyer, Alison, Margaret Controlled release products
FR2753639B1 (fr) * 1996-09-25 1998-12-11 Procede de preparation de microcapsules de matieres actives enrobees par un polymere et nouvelles microcapsules notamment obtenues selon le procede
US5766637A (en) * 1996-10-08 1998-06-16 University Of Delaware Microencapsulation process using supercritical fluids
JP3770917B2 (ja) * 1997-02-17 2006-04-26 株式会社ドペル 人造石の製造方法
GB9800936D0 (en) 1997-05-10 1998-03-11 Univ Nottingham Biofunctional polymers
ES2342747T3 (es) 1997-10-15 2010-07-13 University Of South Florida Recubrimiento de material en particulas asistido por un fluido supercritico.
IT1296464B1 (it) * 1997-11-19 1999-06-25 Vectorpharma Int Composizioni farmaceutiche in forma di polveri di polimeri reticolati caricati con farmaci e relativo processo di preparazione mediante
GB9814619D0 (en) 1998-07-06 1998-09-02 Cole Polytechnique Fudurale De Materials and methods relating to encapsulation
US6340722B1 (en) 1998-09-04 2002-01-22 The University Of Akron Polymerization, compatibilized blending, and particle size control of powder coatings in a supercritical fluid
US6350786B1 (en) * 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers
GB9920558D0 (en) * 1999-08-31 1999-11-03 Bradford Particle Design Ltd Methods for particle formation and their products
US6372259B1 (en) * 1999-11-10 2002-04-16 University Of Iowa Research Foundation Palatable, sustained release drug granules
US6521258B1 (en) * 2000-09-08 2003-02-18 Ferro Corporation Polymer matrices prepared by supercritical fluid processing techniques
AU2001285242A1 (en) 2000-09-08 2002-03-22 Ferro Corporation Controlled-release pharmaceuticals prepared by supercritical fluid processing techniques
EP1401404B1 (en) 2001-05-30 2008-04-16 Csir Method of encapsulating an active substance

Also Published As

Publication number Publication date
GB2392619B (en) 2004-10-20
ZA200309983B (en) 2005-01-26
EP1401404B1 (en) 2008-04-16
DE10296849T5 (de) 2004-04-29
FR2825292B1 (fr) 2006-06-09
US7641917B2 (en) 2010-01-05
US20050112205A1 (en) 2005-05-26
CN1512877A (zh) 2004-07-14
JP4313196B2 (ja) 2009-08-12
JP2005502642A (ja) 2005-01-27
ATE392203T1 (de) 2008-05-15
HK1066488A1 (en) 2005-03-24
DE60226140T2 (de) 2009-05-07
CA2455208A1 (en) 2003-02-20
DK1401404T3 (da) 2008-08-11
CH695418A5 (de) 2006-05-15
ITMI20021169A1 (it) 2003-12-01
ES2305250T3 (es) 2008-11-01
WO2003013478A8 (en) 2003-04-03
CN1255099C (zh) 2006-05-10
GB2392619A (en) 2004-03-10
EP1401404A2 (en) 2004-03-31
WO2003013478A2 (en) 2003-02-20
ITMI20021169A0 (it) 2002-05-30
BR0210000A (pt) 2004-05-04
GB0327381D0 (en) 2003-12-31
DE60226140D1 (de) 2008-05-29
FR2825292A1 (fr) 2002-12-06
CA2455208C (en) 2009-02-03
WO2003013478A3 (en) 2003-05-30
CY1108199T1 (el) 2014-02-12
PT1401404E (pt) 2008-07-23
NL1020706C2 (nl) 2003-04-28
AU2002310567B2 (en) 2005-10-20

Similar Documents

Publication Publication Date Title
NO990790L (no) Blandinger omfattende mikropartikler av vann-ul°selige forbindelser og fremgangsmÕte for fremstilling av samme
CY1110569T1 (el) Συσκευη και μεθοδος για την απομονωση παραγομενων σωματιδιων ως ενα εναιωρημα σε ενα μη-υπερκρισιμο ρευστο
NL193956B (nl) Werkwijze voor het regelen van de geleringssnelheid in een waterige breekvloeistof.
DK1180062T3 (da) Fremgangsmåde til fremstilling af morfologisk ensartede mikro- og nanopartikler ved hjælp af en anordning til mikroblanding
EP1721658A3 (en) Process and apparatus for producing microcapsules
WO2002013786A3 (en) Method of forming microparticles
WO2005037439A3 (en) Method and a device for treating microparticles
WO2002093132A3 (en) Method for manufacture of fine particles
NL1020706A1 (nl) Werkwijze voor het inkapselen van een actieve substantie.
DE60119947D1 (de) Einen wirkstoff enthaltende, beschichtete teilchen
TW200609036A (en) Process for coating powders
MXPA03007635A (es) P-tienilbencilamidas que sirven como agonistas de receptores para angiotensina-(1-7), metodo para su produccion, su uso y preparaciones farmaceuticas que las contienen.
WO2004108117A3 (en) Extended release osmo-microsealed formulation comprising venlafaxine
WO2008054412A3 (en) Method and apparatus for forming chromonic nanoparticles
TW200620450A (en) Supercritical fluid processing system having a coating on internal members and a method of using
DE69932182D1 (de) Präparationen, die virus-ähnliche partikel als immunpotentiatoren enthalten und durch die schleimhaut verabreicht werden.
WO2006017002A3 (en) A method of dispersing fine particles in a spray
WO2003035818A3 (de) Mittel und vorrichtung sowie verfahren zu seiner herstellung
WO2005009411A3 (fr) Particules comprenant un principe actif sous forme de co-precipite
NL1016937A1 (nl) Inrichting en werkwijze voor de afscheiding van vloeibare producten uitgaande van een suspensie, die een vaste stof bevat, en in aanwezigheid van een verdunningsmiddel.
BRPI0409625B1 (pt) mÉtodo de densificar um material de partÍculas a granel, e, aparelho de reduzir tamanho e de densificar um material de partÍculas a granel.
EP1550501A3 (en) Method and apparatus for producing a flowable powdery material
WO2002100378A3 (en) Process for the preparation of a particulate material
WO2003030867A3 (fr) Procede de preparation d'un compose d'interaction d'un derive anilide avec un support poreux par fluide supercritique
WO2003092647A3 (de) Peptid-modifizierte lipide als biologische transportsysteme für mikronutrients

Legal Events

Date Code Title Description
AD1A A request for search or an international type search has been filed
RD2N Patents in respect of which a decision has been taken or a report has been made (novelty report)

Effective date: 20021223

PD2B A search report has been drawn up
MK Patent expired because of reaching the maximum lifetime of a patent

Effective date: 20220528