PT1401404E - Método de encapsular uma substância activa - Google Patents

Método de encapsular uma substância activa Download PDF

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Publication number
PT1401404E
PT1401404E PT02735680T PT02735680T PT1401404E PT 1401404 E PT1401404 E PT 1401404E PT 02735680 T PT02735680 T PT 02735680T PT 02735680 T PT02735680 T PT 02735680T PT 1401404 E PT1401404 E PT 1401404E
Authority
PT
Portugal
Prior art keywords
active substance
inter
coating
product
encapsulating
Prior art date
Application number
PT02735680T
Other languages
English (en)
Inventor
Francis Sean Moolman
Heidi Rolfes
Thilo Lothar Van Der Merwe
Original Assignee
Csir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25589180&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1401404(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Csir filed Critical Csir
Publication of PT1401404E publication Critical patent/PT1401404E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Paints Or Removers (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT02735680T 2001-05-30 2002-05-28 Método de encapsular uma substância activa PT1401404E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ZA200104451 2001-05-30

Publications (1)

Publication Number Publication Date
PT1401404E true PT1401404E (pt) 2008-07-23

Family

ID=25589180

Family Applications (1)

Application Number Title Priority Date Filing Date
PT02735680T PT1401404E (pt) 2001-05-30 2002-05-28 Método de encapsular uma substância activa

Country Status (21)

Country Link
US (1) US7641917B2 (pt)
EP (1) EP1401404B1 (pt)
JP (1) JP4313196B2 (pt)
CN (1) CN1255099C (pt)
AT (1) ATE392203T1 (pt)
AU (1) AU2002310567B2 (pt)
BR (1) BR0210000A (pt)
CA (1) CA2455208C (pt)
CH (1) CH695418A5 (pt)
CY (1) CY1108199T1 (pt)
DE (2) DE60226140T2 (pt)
DK (1) DK1401404T3 (pt)
ES (1) ES2305250T3 (pt)
FR (1) FR2825292B1 (pt)
GB (1) GB2392619B (pt)
HK (1) HK1066488A1 (pt)
IT (1) ITMI20021169A1 (pt)
NL (1) NL1020706C2 (pt)
PT (1) PT1401404E (pt)
WO (1) WO2003013478A2 (pt)
ZA (1) ZA200309983B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1401404T3 (da) 2001-05-30 2008-08-11 Csir Fremgangsmåde til indkapsling af et aktivt stof
US7903319B2 (en) * 2006-07-11 2011-03-08 E Ink Corporation Electrophoretic medium and display with improved image stability
US20080082764A1 (en) * 2006-10-03 2008-04-03 Yi Feng Jang Memory accessing system and method
GB0812742D0 (en) 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Process
GB201317756D0 (en) 2013-10-08 2013-11-20 Critical Pharmaceuticals Ltd New process
DE102018210030A1 (de) * 2018-06-20 2019-12-24 Thyssenkrupp Ag Verwendung und Recyclieren von überkritischen CO2 als Lösungsmittel für PLA und weitere biologisch abbaubaren Polymere in das Beschichtungsverfahren für Düngemittel
IT201800007993A1 (it) * 2018-08-09 2020-02-09 Greenbone Ortho Srl Impianto finalizzato alla trasformazione chimica di materiali nello stato 3d
CN112812355B (zh) * 2020-12-31 2022-09-23 厦门天生爱科技有限公司 一种具有缓释挥发性中草药有效成分的功能高分子发泡材料、制备方法和用途

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8500121D0 (en) 1985-01-03 1985-02-13 Connaught Lab Microencapsulation of living cells
EP0321607B1 (en) * 1987-12-21 1993-09-22 Union Carbide Corporation Supercritical fluids as diluents in liquid spray application of coatings
EP0706821A1 (en) * 1994-10-06 1996-04-17 Centre De Microencapsulation Method of coating particles
US5939485A (en) * 1995-06-19 1999-08-17 Medlogic Global Corporation Responsive polymer networks and methods of their use
EP0844870B1 (en) * 1995-08-17 2001-11-21 Csir Controlled release products
FR2753639B1 (fr) * 1996-09-25 1998-12-11 Procede de preparation de microcapsules de matieres actives enrobees par un polymere et nouvelles microcapsules notamment obtenues selon le procede
US5766637A (en) * 1996-10-08 1998-06-16 University Of Delaware Microencapsulation process using supercritical fluids
JP3770917B2 (ja) * 1997-02-17 2006-04-26 株式会社ドペル 人造石の製造方法
GB9800936D0 (en) 1997-05-10 1998-03-11 Univ Nottingham Biofunctional polymers
EP1028820B1 (en) 1997-10-15 2009-12-30 University Of South Florida Supercritical fluid aided coating of particulate material
IT1296464B1 (it) * 1997-11-19 1999-06-25 Vectorpharma Int Composizioni farmaceutiche in forma di polveri di polimeri reticolati caricati con farmaci e relativo processo di preparazione mediante
GB9814619D0 (en) 1998-07-06 1998-09-02 Cole Polytechnique Fudurale De Materials and methods relating to encapsulation
US6340722B1 (en) 1998-09-04 2002-01-22 The University Of Akron Polymerization, compatibilized blending, and particle size control of powder coatings in a supercritical fluid
US6350786B1 (en) * 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers
GB9920558D0 (en) * 1999-08-31 1999-11-03 Bradford Particle Design Ltd Methods for particle formation and their products
US6372259B1 (en) * 1999-11-10 2002-04-16 University Of Iowa Research Foundation Palatable, sustained release drug granules
US6521258B1 (en) * 2000-09-08 2003-02-18 Ferro Corporation Polymer matrices prepared by supercritical fluid processing techniques
WO2002020624A1 (en) 2000-09-08 2002-03-14 Ferro Corporation Controlled-release pharmaceuticals prepared by supercritical fluid processing techniques
DK1401404T3 (da) 2001-05-30 2008-08-11 Csir Fremgangsmåde til indkapsling af et aktivt stof

Also Published As

Publication number Publication date
WO2003013478A2 (en) 2003-02-20
CA2455208C (en) 2009-02-03
NL1020706A1 (nl) 2002-12-03
FR2825292A1 (fr) 2002-12-06
CY1108199T1 (el) 2014-02-12
GB0327381D0 (en) 2003-12-31
CN1255099C (zh) 2006-05-10
US20050112205A1 (en) 2005-05-26
EP1401404B1 (en) 2008-04-16
AU2002310567B2 (en) 2005-10-20
ZA200309983B (en) 2005-01-26
JP4313196B2 (ja) 2009-08-12
DK1401404T3 (da) 2008-08-11
ITMI20021169A0 (it) 2002-05-30
WO2003013478A8 (en) 2003-04-03
ITMI20021169A1 (it) 2003-12-01
DE10296849T5 (de) 2004-04-29
NL1020706C2 (nl) 2003-04-28
US7641917B2 (en) 2010-01-05
WO2003013478A3 (en) 2003-05-30
DE60226140D1 (de) 2008-05-29
GB2392619B (en) 2004-10-20
DE60226140T2 (de) 2009-05-07
JP2005502642A (ja) 2005-01-27
EP1401404A2 (en) 2004-03-31
ATE392203T1 (de) 2008-05-15
CN1512877A (zh) 2004-07-14
BR0210000A (pt) 2004-05-04
HK1066488A1 (en) 2005-03-24
ES2305250T3 (es) 2008-11-01
CA2455208A1 (en) 2003-02-20
CH695418A5 (de) 2006-05-15
GB2392619A (en) 2004-03-10
FR2825292B1 (fr) 2006-06-09

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