HK1060728A1 - Antagonists of mcp-1 function and methods of use thereof - Google Patents
Antagonists of mcp-1 function and methods of use thereofInfo
- Publication number
- HK1060728A1 HK1060728A1 HK04103275A HK04103275A HK1060728A1 HK 1060728 A1 HK1060728 A1 HK 1060728A1 HK 04103275 A HK04103275 A HK 04103275A HK 04103275 A HK04103275 A HK 04103275A HK 1060728 A1 HK1060728 A1 HK 1060728A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- mcp
- antagonists
- methods
- function
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Quinoline Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27279201P | 2001-03-01 | 2001-03-01 | |
PCT/US2002/006256 WO2002070509A2 (fr) | 2001-03-01 | 2002-02-28 | Antagonistes de la fonction mcp-1 et procede d'utilisation de ceux-ci |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1060728A1 true HK1060728A1 (en) | 2004-08-20 |
Family
ID=23041292
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK04103275A HK1060728A1 (en) | 2001-03-01 | 2004-05-11 | Antagonists of mcp-1 function and methods of use thereof |
Country Status (15)
Country | Link |
---|---|
US (2) | US6809113B2 (fr) |
EP (1) | EP1363897B1 (fr) |
JP (1) | JP4291576B2 (fr) |
KR (1) | KR20040018336A (fr) |
CN (1) | CN1259315C (fr) |
AR (1) | AR035759A1 (fr) |
AT (1) | ATE313537T1 (fr) |
BR (1) | BR0207750A (fr) |
CA (1) | CA2439849A1 (fr) |
DE (1) | DE60208159T2 (fr) |
ES (1) | ES2254653T3 (fr) |
HK (1) | HK1060728A1 (fr) |
MX (1) | MXPA03007861A (fr) |
TW (1) | TWI245761B (fr) |
WO (1) | WO2002070509A2 (fr) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002217999A1 (en) | 2000-11-01 | 2002-05-15 | Cor Therapeutics, Inc. | Process for the production of 4-quinazolinylpiperazin-1-carboxylic acid phenylamides |
US7732162B2 (en) | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
WO2006029173A2 (fr) * | 2004-09-08 | 2006-03-16 | Boys Town National Research Hospital | Traitement d'une maladie de la membrane basale glomerulaire dans laquelle intervient la metalloprotease matricielle 12 |
WO2006103511A1 (fr) | 2005-03-31 | 2006-10-05 | Pfizer Products Inc. | Derives de cyclopentapyridine et de tetrahydroquinoline |
WO2007066496A1 (fr) * | 2005-12-07 | 2007-06-14 | Sumitomo Chemical Company, Limited | Compose benzoyluree et son utilisation |
US7601716B2 (en) * | 2006-05-01 | 2009-10-13 | Cephalon, Inc. | Pyridopyrazines and derivatives thereof as ALK and c-Met inhibitors |
CA2658719A1 (fr) * | 2006-07-24 | 2008-01-31 | Yeda Research And Development Co. Ltd. | Compositions pharmaceutiques comprenant ccl2 et leur utilisation dans le traitement d'une inflammation |
US20080076120A1 (en) * | 2006-09-14 | 2008-03-27 | Millennium Pharmaceuticals, Inc. | Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders |
WO2008055945A1 (fr) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | Dérivés 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one utiles en tant qu' inhibiteurs de la glutaminyl-cyclase dans le traitement des ulcères, du cancer et d'autres maladies |
EP2091948B1 (fr) | 2006-11-30 | 2012-04-18 | Probiodrug AG | Nouveaux inhibiteurs de glutaminylcyclase |
CA2672229A1 (fr) * | 2006-12-14 | 2008-06-19 | Actogenix N.V. | Delivrance de molecules de liaison pour induire une immunomodulation |
MX2009009234A (es) | 2007-03-01 | 2009-12-01 | Probiodrug Ag | Uso nuevo de inhibidores de ciclasa de glutaminilo. |
EP2865670B1 (fr) | 2007-04-18 | 2017-01-11 | Probiodrug AG | Dérivés de thio-urée utilisés comme inhibiteurs de la glutaminyl cyclase |
US8356920B2 (en) * | 2007-12-12 | 2013-01-22 | Levine Jonathan E | Lighting device |
WO2010068881A1 (fr) * | 2008-12-12 | 2010-06-17 | Forest Laboratories Holdings Limited | Nouveaux dérivés de benzodioxane et benzoxazine utiles en tant que ligands pour les récepteurs de chimiokine cc |
ES2548913T3 (es) | 2009-09-11 | 2015-10-21 | Probiodrug Ag | Derivados heterocíclicos como inhibidores de glutaminil ciclasa |
ES2586231T3 (es) | 2010-03-03 | 2016-10-13 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
AU2011226074B2 (en) | 2010-03-10 | 2015-01-22 | Vivoryon Therapeutics N.V. | Heterocyclic inhibitors of glutaminyl cyclase (QC, EC 2.3.2.5) |
EP2560953B1 (fr) | 2010-04-21 | 2016-01-06 | Probiodrug AG | Inhibiteurs de glutaminyl cyclase |
US8530670B2 (en) | 2011-03-16 | 2013-09-10 | Probiodrug Ag | Inhibitors |
EP2522341A1 (fr) * | 2011-05-13 | 2012-11-14 | Tragex Pharma | Compositions pharmaceutiques comportant des inhibiteurs de la neuropiline et leur utilisation dans la prévention et/ou le traitement des troubles angiogènes et des cancers |
EP3071203B1 (fr) | 2013-11-18 | 2020-12-23 | Forma Therapeutics, Inc. | Compositions de tétrahydroquinoline utilisées comme inhibiteurs de protéines à bromodomaine et domaine extraterminal (bet) |
WO2015074081A1 (fr) | 2013-11-18 | 2015-05-21 | Bair Kenneth W | Compositions de benzopipérazine en tant qu'inhibiteurs de bromodomaines bet |
US20180206726A1 (en) | 2016-12-07 | 2018-07-26 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
CA3045310A1 (fr) | 2016-12-14 | 2018-06-21 | Progenity, Inc. | Traitement d'une maladie du tractus gastro-intestinal avec une chimoikine/un inhibiteur du recepteur de chimiokine |
US11351227B2 (en) * | 2017-04-27 | 2022-06-07 | Washington University | Chemokine decoy receptors of rodent gammaherpesviruses and uses thereof |
DK3461819T3 (da) | 2017-09-29 | 2020-08-10 | Probiodrug Ag | Inhibitorer af glutaminylcyklase |
EP3643711A1 (fr) | 2018-10-24 | 2020-04-29 | Bayer Animal Health GmbH | Nouveaux composés anthelminthiques |
WO2020106754A1 (fr) | 2018-11-19 | 2020-05-28 | Progenity, Inc. | Méthodes et dispositifs pour traiter une maladie à l'aide d'agents biothérapeutiques |
WO2021119482A1 (fr) | 2019-12-13 | 2021-06-17 | Progenity, Inc. | Dispositif ingérable pour administrer un agent thérapeutique dans le tractus gastro-intestinal |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE32700B1 (en) | 1968-02-03 | 1973-10-31 | Beecham Group Ltd | Penicillins |
GB1250611A (fr) | 1968-02-03 | 1971-10-20 | ||
DE2131034A1 (de) | 1971-06-23 | 1973-01-11 | Hoechst Ag | Acylharnstoffe und verfahren zu ihrer herstellung |
DE2652004C3 (de) | 1976-11-15 | 1979-09-13 | Basf Ag, 6700 Ludwigshafen | l-Acyl-2-arylamino-2-imidazoline, Verfahren zu ihrer Herstellung und ihre Verwendung |
US4163784A (en) | 1978-03-09 | 1979-08-07 | Pfizer Inc. | Heterocyclylcarbonyl derivatives of urea, agents for dissolution of gallstones |
GB8528234D0 (en) | 1985-11-15 | 1985-12-18 | Wyeth John & Brother Ltd | Heterocyclic compounds |
JP2650055B2 (ja) | 1988-11-28 | 1997-09-03 | キヤノン株式会社 | 電子写真感光体 |
FR2672888B1 (fr) | 1991-02-14 | 1994-02-04 | Fabre Medicament Pierre | Nouvelles urees et thiourees, leur preparation et leur application en therapeutique. |
JP3964478B2 (ja) | 1995-06-30 | 2007-08-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬 |
WO1997024325A1 (fr) | 1995-12-28 | 1997-07-10 | Takeda Chemical Industries, Ltd. | DERIVES DE DIPHENYLMETHANE UTILISES COMME ANTAGONISTES DU RECEPTEUR MIP-1α/RANTES |
JPH09255572A (ja) | 1996-03-26 | 1997-09-30 | Takeda Chem Ind Ltd | ケモカイン受容体拮抗剤 |
WO1997044329A1 (fr) | 1996-05-20 | 1997-11-27 | Teijin Limited | Derives de diamine cyclique de diarylaklyle utilises en tant qu'antagonistes des recepteurs de chimiokines |
CA2259927A1 (fr) | 1996-07-12 | 1998-01-22 | Leukosite, Inc. | Antagonistes des recepteurs de la chemokine et procedes d'utilisation de ces derniers |
CA2261633A1 (fr) | 1996-07-29 | 1998-02-05 | Banyu Pharmaceutical Co., Ltd. | Antagonistes de recepteurs de chemokines |
WO1998006703A1 (fr) | 1996-08-14 | 1998-02-19 | Warner-Lambert Company | Derives 2-phenyle benzimidazole en tant qu'antagonistes de mcp-1 |
AU5812498A (en) | 1996-12-20 | 1998-07-17 | Merck & Co., Inc. | Substituted aminoquinolines as modulators of chemokine receptor activity |
GB9716656D0 (en) | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
WO1999040072A1 (fr) | 1998-02-03 | 1999-08-12 | Boehringer Ingelheim Pharma Kg | Heterocycles benzo condenses a 5 chainons utilises comme agents antithrombotiques |
US6342516B1 (en) | 1998-07-31 | 2002-01-29 | Nippon Soda Co., Ltd. | Phenylazole compounds, process for producing the same and drugs for hyperlipemia |
US6316449B1 (en) | 1999-07-08 | 2001-11-13 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists |
US6777413B2 (en) | 2000-02-01 | 2004-08-17 | Millennium Pharmaceuticals, Inc. | 2-[1H]-quinolone and 2-[1H]-quinoxalone inhibitors of factor Xa |
AU2001236606A1 (en) | 2000-02-01 | 2001-08-14 | Cor Therapeutics, Inc. | 3,4-dihydro-2h-benzo(1,4)oxazine inhibitors of factor xa |
AU2001230537A1 (en) | 2000-02-01 | 2001-08-14 | Daiichi Pharmaceutical Co., Ltd. | Pyridoxazine derivatives |
-
2002
- 2002-02-25 TW TW091103254A patent/TWI245761B/zh not_active IP Right Cessation
- 2002-02-27 US US10/087,208 patent/US6809113B2/en not_active Expired - Fee Related
- 2002-02-28 BR BR0207750-7A patent/BR0207750A/pt not_active IP Right Cessation
- 2002-02-28 CA CA002439849A patent/CA2439849A1/fr not_active Abandoned
- 2002-02-28 WO PCT/US2002/006256 patent/WO2002070509A2/fr active IP Right Grant
- 2002-02-28 DE DE60208159T patent/DE60208159T2/de not_active Expired - Fee Related
- 2002-02-28 JP JP2002569829A patent/JP4291576B2/ja not_active Expired - Fee Related
- 2002-02-28 KR KR10-2003-7011481A patent/KR20040018336A/ko active IP Right Grant
- 2002-02-28 AT AT02709746T patent/ATE313537T1/de not_active IP Right Cessation
- 2002-02-28 AR ARP020100728A patent/AR035759A1/es unknown
- 2002-02-28 MX MXPA03007861A patent/MXPA03007861A/es active IP Right Grant
- 2002-02-28 ES ES02709746T patent/ES2254653T3/es not_active Expired - Lifetime
- 2002-02-28 EP EP02709746A patent/EP1363897B1/fr not_active Expired - Lifetime
- 2002-02-28 CN CNB028057929A patent/CN1259315C/zh not_active Expired - Fee Related
-
2004
- 2004-05-11 HK HK04103275A patent/HK1060728A1/xx not_active IP Right Cessation
- 2004-10-19 US US10/969,440 patent/US7297696B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2004527503A (ja) | 2004-09-09 |
TWI245761B (en) | 2005-12-21 |
WO2002070509A3 (fr) | 2003-05-30 |
US20050054668A1 (en) | 2005-03-10 |
EP1363897A2 (fr) | 2003-11-26 |
CA2439849A1 (fr) | 2002-09-12 |
AR035759A1 (es) | 2004-07-07 |
BR0207750A (pt) | 2004-03-23 |
US6809113B2 (en) | 2004-10-26 |
DE60208159D1 (de) | 2006-01-26 |
ES2254653T3 (es) | 2006-06-16 |
DE60208159T2 (de) | 2006-08-17 |
KR20040018336A (ko) | 2004-03-03 |
US7297696B2 (en) | 2007-11-20 |
WO2002070509A8 (fr) | 2003-11-06 |
WO2002070509A2 (fr) | 2002-09-12 |
EP1363897B1 (fr) | 2005-12-21 |
ATE313537T1 (de) | 2006-01-15 |
MXPA03007861A (es) | 2004-10-15 |
CN1494539A (zh) | 2004-05-05 |
JP4291576B2 (ja) | 2009-07-08 |
CN1259315C (zh) | 2006-06-14 |
US20030105085A1 (en) | 2003-06-05 |
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