HK1052512B - 西酞普蘭的製備方法 - Google Patents

西酞普蘭的製備方法

Info

Publication number
HK1052512B
HK1052512B HK03104874.0A HK03104874A HK1052512B HK 1052512 B HK1052512 B HK 1052512B HK 03104874 A HK03104874 A HK 03104874A HK 1052512 B HK1052512 B HK 1052512B
Authority
HK
Hong Kong
Prior art keywords
preparation
citalopram
phtalid
cyano
new
Prior art date
Application number
HK03104874.0A
Other languages
English (en)
Other versions
HK1052512A1 (en
Inventor
Petersen Hans
Harold Rock Michael
Original Assignee
H. 隆德貝克有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. 隆德貝克有限公司 filed Critical H. 隆德貝克有限公司
Publication of HK1052512A1 publication Critical patent/HK1052512A1/xx
Publication of HK1052512B publication Critical patent/HK1052512B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44Palladium
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/70Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
    • B01J23/74Iron group metals
    • B01J23/755Nickel
HK03104874.0A 1999-12-30 2003-07-08 西酞普蘭的製備方法 HK1052512B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/DK1999/000740 WO2001049672A1 (en) 1999-12-30 1999-12-30 Method for the preparation of citalopram

Publications (2)

Publication Number Publication Date
HK1052512A1 HK1052512A1 (en) 2003-09-19
HK1052512B true HK1052512B (zh) 2006-03-03

Family

ID=8157174

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03104874.0A HK1052512B (zh) 1999-12-30 2003-07-08 西酞普蘭的製備方法

Country Status (28)

Country Link
US (2) US20020198391A1 (zh)
EP (1) EP1246813B1 (zh)
JP (1) JP2003519218A (zh)
KR (1) KR100653141B1 (zh)
CN (1) CN1211377C (zh)
AT (1) ATE253568T1 (zh)
AU (1) AU1858400A (zh)
BR (1) BR9917604A (zh)
CA (1) CA2395733C (zh)
CZ (1) CZ20022627A3 (zh)
DE (1) DE69912652T2 (zh)
DK (1) DK1246813T3 (zh)
EA (1) EA004055B1 (zh)
ES (1) ES2207312T3 (zh)
HK (1) HK1052512B (zh)
HR (1) HRP20020633A2 (zh)
HU (1) HUP0203840A3 (zh)
IL (2) IL150367A0 (zh)
IS (1) IS2167B (zh)
MX (1) MXPA02006504A (zh)
NO (1) NO328359B1 (zh)
PL (1) PL198803B1 (zh)
PT (1) PT1246813E (zh)
SI (1) SI1246813T1 (zh)
SK (1) SK11052002A3 (zh)
TR (1) TR200201688T2 (zh)
UA (1) UA73336C2 (zh)
WO (1) WO2001049672A1 (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2195554T5 (es) * 1999-04-14 2010-02-02 H. Lundbeck A/S Metodo para la preparacion de citalopram.
AU778751B2 (en) 1999-12-28 2004-12-16 H. Lundbeck A/S Method for the preparation of citalopram
WO2001051477A1 (en) 2000-01-14 2001-07-19 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
JP2003527385A (ja) 2000-03-13 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット 5−置換された1−(4−フルオロフェニル)−1,3−ジヒドロイソベンゾフランの段階的アルキル化法
PL360110A1 (en) 2000-03-13 2004-09-06 H.Lundbeck A/S Method for the preparation of citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
PL360107A1 (en) 2000-03-14 2004-09-06 H.Lundbeck A/S Method for the preparation of citalopram
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
US6339182B1 (en) * 2000-06-20 2002-01-15 Chevron U.S.A. Inc. Separation of olefins from paraffins using ionic liquid solutions
AU2003223105A1 (en) * 2003-03-24 2004-10-18 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
CN100457747C (zh) * 2006-11-21 2009-02-04 浙江大学 抗抑郁药西酞普兰关键中间体5-氰基苯酞的制备工艺
CN103127815B (zh) * 2013-02-19 2015-10-28 浙江大学 一种利用卤硫作用提高二氧化硫捕集性能的方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (zh) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
US4665181A (en) * 1984-05-17 1987-05-12 Pennwalt Corporation Anti-inflammatory phthalazinones
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
JPH0881456A (ja) * 1994-09-14 1996-03-26 Sumitomo Chem Co Ltd 1,1,3,3−テトラクロロ−1,3−ジヒドロイソベンゾフラン誘導体の製造法
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
DK1015416T3 (da) 1997-07-08 2001-11-05 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
JP3813820B2 (ja) 1997-11-11 2006-08-23 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
EA002977B1 (ru) 1998-10-20 2002-12-26 Х.Лундбекк А/С Способ получения циталопрама
PT1140886E (pt) 1998-12-23 2003-08-29 Lundbeck & Co As H Metodo para a preparacao de 5- cianoftalida
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
ES2195554T5 (es) 1999-04-14 2010-02-02 H. Lundbeck A/S Metodo para la preparacion de citalopram.
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ES2169709A1 (es) 1999-10-25 2002-07-01 Lundbeck & Co As H Metodo para la preparacion de citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
AU778751B2 (en) 1999-12-28 2004-12-16 H. Lundbeck A/S Method for the preparation of citalopram
WO2001051477A1 (en) 2000-01-14 2001-07-19 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
FR2805812A1 (fr) 2000-02-24 2001-09-07 Lundbeck & Co As H Procede de preparation du citalopram
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IL144817A0 (en) 2000-08-18 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
CA2360303C (en) 2000-12-22 2003-08-12 Marco Villa Process for the preparation of pure citalopram
EP1181272B1 (en) 2000-12-28 2002-08-28 H. Lundbeck A/S Process for the preparation of pure citalopram

Also Published As

Publication number Publication date
EA200200728A1 (ru) 2002-12-26
HUP0203840A2 (en) 2003-05-28
UA73336C2 (en) 2005-07-15
HRP20020633A2 (en) 2004-12-31
TR200201688T2 (tr) 2002-11-21
KR100653141B1 (ko) 2006-12-01
MXPA02006504A (es) 2002-12-09
WO2001049672A1 (en) 2001-07-12
IL150367A0 (en) 2002-12-01
EA004055B1 (ru) 2003-12-25
EP1246813A1 (en) 2002-10-09
NO328359B1 (no) 2010-02-01
PT1246813E (pt) 2004-02-27
CA2395733A1 (en) 2001-07-12
NO20023150D0 (no) 2002-06-28
SK11052002A3 (sk) 2003-01-09
NO20023150L (no) 2002-06-28
SI1246813T1 (en) 2004-08-31
CZ20022627A3 (cs) 2002-10-16
BR9917604A (pt) 2002-12-31
US7271273B2 (en) 2007-09-18
CN1391566A (zh) 2003-01-15
US20060079700A1 (en) 2006-04-13
ATE253568T1 (de) 2003-11-15
AU1858400A (en) 2001-07-16
DE69912652T2 (de) 2004-06-09
US20020198391A1 (en) 2002-12-26
CN1211377C (zh) 2005-07-20
DE69912652D1 (de) 2003-12-11
KR20020073495A (ko) 2002-09-26
ES2207312T3 (es) 2004-05-16
IS2167B (is) 2006-11-15
JP2003519218A (ja) 2003-06-17
DK1246813T3 (da) 2004-03-01
HUP0203840A3 (en) 2005-02-28
EP1246813B1 (en) 2003-11-05
PL355531A1 (en) 2004-05-04
IS6433A (is) 2002-06-19
IL150367A (en) 2010-06-16
HK1052512A1 (en) 2003-09-19
CA2395733C (en) 2007-03-20
PL198803B1 (pl) 2008-07-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20121230