HK1051218A1 - Process for producing trans-4-hydroxy-l-proline. - Google Patents

Process for producing trans-4-hydroxy-l-proline.

Info

Publication number
HK1051218A1
HK1051218A1 HK03103458A HK03103458A HK1051218A1 HK 1051218 A1 HK1051218 A1 HK 1051218A1 HK 03103458 A HK03103458 A HK 03103458A HK 03103458 A HK03103458 A HK 03103458A HK 1051218 A1 HK1051218 A1 HK 1051218A1
Authority
HK
Hong Kong
Prior art keywords
proline
hydroxy
trans
useful
aqueous medium
Prior art date
Application number
HK03103458A
Other languages
English (en)
Inventor
Ozaki Akio
Mori Hideo
Shibasaki Takeshi
Ando Katsuhiko
Chiba Shigeru
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Publication of HK1051218A1 publication Critical patent/HK1051218A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/24—Proline; Hydroxyproline; Histidine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
    • C12Y114/11002—Procollagen-proline dioxygenase (1.14.11.2), i.e. proline-hydroxylase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK03103458A 1993-09-07 2003-05-16 Process for producing trans-4-hydroxy-l-proline. HK1051218A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22194093 1993-09-07
JP33256193 1993-12-27

Publications (1)

Publication Number Publication Date
HK1051218A1 true HK1051218A1 (en) 2003-07-25

Family

ID=26524587

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03103458A HK1051218A1 (en) 1993-09-07 2003-05-16 Process for producing trans-4-hydroxy-l-proline.

Country Status (7)

Country Link
EP (1) EP0641862B1 (zh)
KR (1) KR100356926B1 (zh)
CN (2) CN1085253C (zh)
AT (1) ATE210729T1 (zh)
DE (1) DE69429396T2 (zh)
ES (1) ES2164675T3 (zh)
HK (1) HK1051218A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1132938C (zh) * 1995-03-07 2003-12-31 协和发酵工业株式会社 生产反－4－羟基－l－脯氨酸的方法
JP3739143B2 (ja) * 1996-09-03 2006-01-25 協和醗酵工業株式会社 トランス−４−ヒドロキシ−ｌ−プロリンの製造法
CA2234412C (en) * 1997-06-09 2008-09-02 Kyowa Hakko Kogyo Co., Ltd. Method for producing optically active compound
DK2847327T3 (en) 2012-05-08 2019-03-11 Codexis Inc BIO-CATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS
CN104428313B (zh) 2012-05-11 2017-11-17 科德克希思公司 工程化亚胺还原酶以及用于酮和胺化合物的还原胺化的方法
HUE053379T2 (hu) 2013-11-13 2021-06-28 Codexis Inc Génmódosított imin-reduktázok és eljárások keton és amin vegyületek reduktív aminálására
US10370648B2 (en) 2014-11-25 2019-08-06 Codexis, Inc. Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
CN105483069B (zh) * 2015-12-09 2019-01-18 浙江绿创生物科技有限公司 一株生产反式-4-羟基-l-脯氨酸的重组菌株及其构建与应用
WO2017213758A1 (en) 2016-06-09 2017-12-14 Codexis, Inc. Biocatalysts and methods for hydroxylation of chemical compounds
WO2017218325A1 (en) 2016-06-15 2017-12-21 Codexis, Inc. Engineered beta-glucosidases and glucosylation methods
WO2018038906A1 (en) 2016-08-26 2018-03-01 Codexis, Inc. Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
CN116855551A (zh) * 2023-08-22 2023-10-10 石家庄市冀荣药业有限公司 一种生物法转化生产l-羟脯氨酸的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190350A1 (en) * 1984-07-31 1986-08-13 NAGAI, Yoshiki Process for preparing human proline hydroxylase
US5374542A (en) * 1991-08-26 1994-12-20 Kyowa Hakko Kogyo Co., Ltd. Process for producing 4-hydroxy-L-proline
JPH05236980A (ja) * 1991-12-17 1993-09-17 Sankyo Co Ltd トランス−４−ヒドロキシ−ｌ−プロリンの製造法

Also Published As

Publication number Publication date
DE69429396T2 (de) 2002-06-13
ES2164675T3 (es) 2002-03-01
DE69429396D1 (de) 2002-01-24
KR950008692A (ko) 1995-04-19
ATE210729T1 (de) 2001-12-15
EP0641862A3 (en) 1997-06-04
KR100356926B1 (ko) 2003-01-10
EP0641862A2 (en) 1995-03-08
CN1106457A (zh) 1995-08-09
CN1085253C (zh) 2002-05-22
CN1392257A (zh) 2003-01-22
CN1171992C (zh) 2004-10-20
EP0641862B1 (en) 2001-12-12

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090905