CA2131775A1 - Process for producing trans-4-hydroxy-l-proline - Google Patents
Process for producing trans-4-hydroxy-l-prolineInfo
- Publication number
- CA2131775A1 CA2131775A1 CA002131775A CA2131775A CA2131775A1 CA 2131775 A1 CA2131775 A1 CA 2131775A1 CA 002131775 A CA002131775 A CA 002131775A CA 2131775 A CA2131775 A CA 2131775A CA 2131775 A1 CA2131775 A1 CA 2131775A1
- Authority
- CA
- Canada
- Prior art keywords
- proline
- hydroxy
- trans
- useful
- aqueous medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Provided is a process for industrially producing trans-4-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is converted into trans-4-hydroxy-L-proline in the presence of an enzyme source which is derived from a microorganism belonging to the genus Dactylosporangium or Amycolatopsis and which catalyzes the hydroxylation of L-proline into trans-4-hydroxy-L-proline, a divalent iron ion and 2-ketoglutaric acid, in an aqueous medium, and the produced trans-4-hydroxy-L-proline is collected from the aqueous medium. Also provided is a novel enzyme L-proline-4-hydroxylase, which is useful for the process.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP332561/93 | 1993-12-27 | ||
JP33256193 | 1993-12-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2131775A1 true CA2131775A1 (en) | 1995-06-28 |
CA2131775C CA2131775C (en) | 2002-02-26 |
Family
ID=18256303
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002131775A Expired - Fee Related CA2131775C (en) | 1993-12-27 | 1994-09-09 | Process for producing trans-4-hydroxy-l-proline |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2131775C (en) |
-
1994
- 1994-09-09 CA CA002131775A patent/CA2131775C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2131775C (en) | 2002-02-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |