HK1050905A1 - Process for the preparation of peptides - Google Patents

Process for the preparation of peptides

Info

Publication number
HK1050905A1
HK1050905A1 HK03103038.5A HK03103038A HK1050905A1 HK 1050905 A1 HK1050905 A1 HK 1050905A1 HK 03103038 A HK03103038 A HK 03103038A HK 1050905 A1 HK1050905 A1 HK 1050905A1
Authority
HK
Hong Kong
Prior art keywords
preparation
peptides
activated carboxylic
anion
component
Prior art date
Application number
HK03103038.5A
Other languages
English (en)
Inventor
Ivo Franci Eggen
Kortenaar Paulus Bernardus Wilhelmus Ten
Original Assignee
Msd Oss Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Msd Oss Bv filed Critical Msd Oss Bv
Publication of HK1050905A1 publication Critical patent/HK1050905A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK03103038.5A 2001-07-19 2003-04-29 Process for the preparation of peptides HK1050905A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01202751 2001-07-19

Publications (1)

Publication Number Publication Date
HK1050905A1 true HK1050905A1 (en) 2003-07-11

Family

ID=8180655

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03103038.5A HK1050905A1 (en) 2001-07-19 2003-04-29 Process for the preparation of peptides

Country Status (25)

Country Link
US (2) US6864357B2 (xx)
EP (1) EP1277761B1 (xx)
JP (1) JP3579038B2 (xx)
KR (1) KR100869520B1 (xx)
CN (1) CN1254482C (xx)
AR (1) AR035258A1 (xx)
AT (1) ATE531724T1 (xx)
AU (1) AU2002300166C1 (xx)
BR (1) BRPI0202779B1 (xx)
CA (1) CA2394216C (xx)
DK (1) DK1277761T3 (xx)
EC (1) ECSP024292A (xx)
ES (1) ES2374389T3 (xx)
HK (1) HK1050905A1 (xx)
HR (1) HRP20020608A2 (xx)
HU (1) HUP0202370A2 (xx)
IL (1) IL150600A (xx)
MX (1) MXPA02006997A (xx)
NO (1) NO326377B1 (xx)
PE (1) PE20030215A1 (xx)
PL (1) PL355126A1 (xx)
RU (1) RU2242457C2 (xx)
SG (1) SG120874A1 (xx)
TW (1) TWI243826B (xx)
ZA (1) ZA200205408B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI247012B (en) * 2001-07-19 2006-01-11 Akzo Nobel Nv Process for rapid solution synthesis of peptides
US7393277B2 (en) * 2003-08-25 2008-07-01 Igt Horseshoe payline system and games using that system
EP1790656A1 (en) 2005-11-25 2007-05-30 Nanokem S.A. Solution-phase synthesis of leuprolide
ES2340885T3 (es) * 2006-01-17 2010-06-10 N.V. Organon Hidrolisis enzimatica selectiva de esteres terc-butilicos c terminal de peptidos.
JP4684124B2 (ja) * 2006-02-16 2011-05-18 富士通株式会社 移動局装置及び同装置における送信電力制御方法
US8716439B2 (en) 2006-03-01 2014-05-06 Kaneka Corporation Method of producing peptide
US7601062B2 (en) * 2006-11-06 2009-10-13 Igt Gaming device and method including moving paylines
US8124372B2 (en) * 2007-06-25 2012-02-28 N.V. Organon Selective enzymatic amidation of C-terminal esters or acids of peptides
EP2755690B1 (en) 2011-08-04 2020-04-01 Merck Sharp & Dohme B.V. Kisspeptide-pentasaccharide conjugates
US9177447B2 (en) 2012-09-25 2015-11-03 Igt Gaming system and method for providing a symbol matrix with a moveable symbol display window
EP2907809B1 (en) * 2014-02-14 2018-08-22 Corden Pharma International GmbH Base-free process for the preparation of ketone intermediates usable for manufacture of nebivolol
JPWO2021192488A1 (xx) * 2020-03-27 2021-09-30

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221754A (en) * 1989-06-09 1993-06-22 Research Corporation Technologies, Inc. Reagents for rapid peptide synthesis
US5101059A (en) * 1989-12-05 1992-03-31 Research Corporation Technologies, Inc. Amino acid protecting groups
US5516892A (en) * 1992-12-28 1996-05-14 Indiana University Foundation Polymer-bound mixed carboxylic anhdrides as a stable form of activated carboxylic acids
US6310180B1 (en) * 1993-06-21 2001-10-30 Vanderbilt University Method for synthesis of proteins
US5516639A (en) * 1993-07-22 1996-05-14 Mayo Foundation For Medical Education And Research Antibodies specific for human prostate glandular kallkrein
US5849954A (en) * 1996-01-18 1998-12-15 Research Corporation Technologies, Inc. Method of peptide synthesis
US6306959B1 (en) * 1996-05-03 2001-10-23 Warner Lambert Company Rapid purification by polymer supported quench
US6121488A (en) * 1997-09-24 2000-09-19 Warner-Lambert Company Quenching reagents for solution phase synthesis
JPH11217397A (ja) * 1997-11-27 1999-08-10 Saburo Aimoto ペプチドチオールエステルの製造方法
FR2780061B1 (fr) * 1998-06-22 2001-09-07 Rhone Poulenc Rorer Sa Nouveau procede de preparation de derives de cyclosporine
WO2000071567A2 (en) * 1999-05-06 2000-11-30 Human Genome Sciences, Inc. Fibroblast growth factor 13
EP1180115A1 (en) * 1999-05-26 2002-02-20 Abbott Laboratories Minimal isolation peptide synthesis process using ion-exchange resins as scavenging agents
US20020127219A1 (en) * 1999-12-30 2002-09-12 Okkels Jens Sigurd Lysosomal enzymes and lysosomal enzyme activators
EP1301604B1 (en) * 2000-07-19 2008-05-28 Pharmacia & Upjohn Company LLC Substrates and assays for beta-secretase activity

Also Published As

Publication number Publication date
JP2003073396A (ja) 2003-03-12
EP1277761B1 (en) 2011-11-02
ZA200205408B (en) 2002-09-05
EP1277761A2 (en) 2003-01-22
US20050101764A1 (en) 2005-05-12
AU2002300166C1 (en) 2006-04-13
JP3579038B2 (ja) 2004-10-20
CN1398875A (zh) 2003-02-26
BR0202779A (pt) 2003-05-13
HUP0202370A2 (hu) 2003-10-28
EP1277761A3 (en) 2007-04-11
NO326377B1 (no) 2008-11-17
ES2374389T3 (es) 2012-02-16
CN1254482C (zh) 2006-05-03
HU0202370D0 (xx) 2002-09-28
HRP20020608A2 (en) 2003-02-28
US20030018163A1 (en) 2003-01-23
MXPA02006997A (es) 2003-07-14
ECSP024292A (es) 2002-09-27
PL355126A1 (en) 2003-01-27
TWI243826B (en) 2005-11-21
NO20023445L (no) 2003-01-20
AR035258A1 (es) 2004-05-05
BRPI0202779B1 (pt) 2016-01-05
KR20030009187A (ko) 2003-01-29
CA2394216A1 (en) 2003-01-19
ATE531724T1 (de) 2011-11-15
CA2394216C (en) 2009-11-03
IL150600A0 (en) 2003-02-12
NO20023445D0 (no) 2002-07-18
AU2002300166B2 (en) 2005-02-17
DK1277761T3 (da) 2012-02-20
PE20030215A1 (es) 2003-03-17
US6864357B2 (en) 2005-03-08
RU2002119631A (ru) 2004-01-20
IL150600A (en) 2005-09-25
RU2242457C2 (ru) 2004-12-20
KR100869520B1 (ko) 2008-11-19
SG120874A1 (en) 2006-04-26

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Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20220714