HK1048319A1 - 新的季銨化合物,其製備方法和其藥物用途 - Google Patents

新的季銨化合物,其製備方法和其藥物用途

Info

Publication number
HK1048319A1
HK1048319A1 HK03100574.1A HK03100574A HK1048319A1 HK 1048319 A1 HK1048319 A1 HK 1048319A1 HK 03100574 A HK03100574 A HK 03100574A HK 1048319 A1 HK1048319 A1 HK 1048319A1
Authority
HK
Hong Kong
Prior art keywords
sub
quaternary ammonium
pharmaceutical use
preparing same
ammonium derivatives
Prior art date
Application number
HK03100574.1A
Other languages
English (en)
Inventor
J-C‧梅德爾蒙特
I‧吉勞德
C‧尼科拉斯
J-C‧毛裡澤斯
M‧拉普
M‧奧裡爾
P‧雷納德
D-H‧蓋傑納德
Original Assignee
瑟維爾實驗室
國家健康科學研究所
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 瑟維爾實驗室, 國家健康科學研究所 filed Critical 瑟維爾實驗室
Publication of HK1048319A1 publication Critical patent/HK1048319A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D259/00Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/021,2-Thiazines; Hydrogenated 1,2-thiazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005Compounds without a metal-carbon linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06Aminosugars
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function
HK03100574.1A 1999-06-23 2003-01-23 新的季銨化合物,其製備方法和其藥物用途 HK1048319A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9908020A FR2795412B1 (fr) 1999-06-23 1999-06-23 Nouveaux derives d'ammonium quaternaire, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2000/001731 WO2001000621A1 (fr) 1999-06-23 2000-06-22 Derives d'ammonium quaternaire, leur procede de preparation et leur usage en pharmacie

Publications (1)

Publication Number Publication Date
HK1048319A1 true HK1048319A1 (zh) 2003-03-28

Family

ID=9547207

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03100574.1A HK1048319A1 (zh) 1999-06-23 2003-01-23 新的季銨化合物,其製備方法和其藥物用途

Country Status (21)

Country Link
US (2) US6759406B1 (zh)
EP (1) EP1185526B1 (zh)
JP (1) JP2003503407A (zh)
KR (1) KR20020016846A (zh)
CN (1) CN1370161A (zh)
AT (1) ATE276251T1 (zh)
AU (1) AU771865B2 (zh)
BR (1) BR0011943A (zh)
CA (1) CA2377154A1 (zh)
DE (1) DE60013818T2 (zh)
EA (1) EA004292B1 (zh)
ES (1) ES2231222T3 (zh)
FR (1) FR2795412B1 (zh)
HK (1) HK1048319A1 (zh)
HU (1) HUP0201552A3 (zh)
MX (1) MXPA01013148A (zh)
NO (1) NO20016267L (zh)
NZ (1) NZ516337A (zh)
PL (1) PL353032A1 (zh)
WO (1) WO2001000621A1 (zh)
ZA (1) ZA200109850B (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19627523C1 (de) 1996-07-09 1997-10-23 Alpha Calcit Fuellstoff Gmbh Verfahren zur Wiederverwertung von Füllstoffen und Streichpigmenten der Papier-, Pappe- und Kartonherstellung
FR2818641B1 (fr) * 2000-12-21 2004-03-05 Servier Lab Nouveaux derives de 1,1-dioxo-2h-1,2-benzothiazine 3-carboxamides, leur procede de preparation et les compositions pharmaceutiques que les contiennent
CN104987296B (zh) * 2006-10-03 2018-11-23 于崇曦 具有快速皮肤穿透速度的带正电荷的水溶性的芥子类化合物及其相关化合物的前药
EP2077991B1 (en) 2006-10-03 2014-02-26 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of mustards and related compounds with very high skin penetration rates
FR2981849B1 (fr) * 2011-10-28 2014-01-03 Univ Claude Bernard Lyon Nanoparticules fonctionnalisees pour le ciblage des proteoglycanes et leurs applications
EP2639227A1 (en) * 2012-03-14 2013-09-18 Bracco Imaging S.p.A A new class of diazepine derivative chelating agents and complexes with paramagnetic metals as MRI contrast agents
FR2989280B1 (fr) 2012-04-13 2017-02-24 Univ Claude Bernard Lyon Nanoparticules ultrafines comme agent de contraste multimodal
WO2016016272A1 (en) 2014-07-28 2016-02-04 Institut National De La Sante Et De La Recherche Medicale (Inserm) Macrocyclic complexes, their process of preparation and use as pet imaging agents
FR3072281B1 (fr) 2017-10-13 2020-12-04 Nh Theraguix Nanovecteurs et utilisations, en particulier pour le traitement de tumeurs
GB202102243D0 (en) 2021-02-17 2021-03-31 Royal Veterinary College New compounds and uses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4623486A (en) * 1985-05-29 1986-11-18 Pfizer Inc. [4-substituted benzoyloxy]-N-substituted-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides having anti-arthritic activity
IL115113A (en) * 1995-08-31 2002-11-10 Israel State 3-carbamoyloxy pyridinium derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EA200200041A1 (ru) 2002-06-27
ATE276251T1 (de) 2004-10-15
BR0011943A (pt) 2002-05-14
HUP0201552A2 (en) 2002-08-28
ZA200109850B (en) 2003-02-26
US20040208822A1 (en) 2004-10-21
DE60013818T2 (de) 2005-11-17
CA2377154A1 (fr) 2001-01-04
FR2795412A1 (fr) 2000-12-29
US6759406B1 (en) 2004-07-06
ES2231222T3 (es) 2005-05-16
EP1185526B1 (fr) 2004-09-15
PL353032A1 (en) 2003-10-06
AU5989300A (en) 2001-01-31
WO2001000621A1 (fr) 2001-01-04
NO20016267L (no) 2002-01-30
KR20020016846A (ko) 2002-03-06
NO20016267D0 (no) 2001-12-20
US7008613B2 (en) 2006-03-07
MXPA01013148A (es) 2004-08-19
AU771865B2 (en) 2004-04-01
EA004292B1 (ru) 2004-02-26
DE60013818D1 (de) 2004-10-21
NZ516337A (en) 2003-11-28
CN1370161A (zh) 2002-09-18
HUP0201552A3 (en) 2004-03-01
EP1185526A1 (fr) 2002-03-13
FR2795412B1 (fr) 2001-07-13
JP2003503407A (ja) 2003-01-28

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