DK1165584T3 - 2'-substitueret RNA fremstilling - Google Patents

2'-substitueret RNA fremstilling

Info

Publication number
DK1165584T3
DK1165584T3 DK00909534T DK00909534T DK1165584T3 DK 1165584 T3 DK1165584 T3 DK 1165584T3 DK 00909534 T DK00909534 T DK 00909534T DK 00909534 T DK00909534 T DK 00909534T DK 1165584 T3 DK1165584 T3 DK 1165584T3
Authority
DK
Denmark
Prior art keywords
compound
formula
rna preparation
substituted rna
sup
Prior art date
Application number
DK00909534T
Other languages
English (en)
Inventor
Colin Bernard Reese
Quanlai Song
Original Assignee
Avecia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avecia Ltd filed Critical Avecia Ltd
Application granted granted Critical
Publication of DK1165584T3 publication Critical patent/DK1165584T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK00909534T 1999-03-19 2000-03-15 2'-substitueret RNA fremstilling DK1165584T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9906328.1A GB9906328D0 (en) 1999-03-19 1999-03-19 2-Substituted RNA preparation
PCT/GB2000/000965 WO2000056747A1 (en) 1999-03-19 2000-03-15 2'-substituted rna preparation

Publications (1)

Publication Number Publication Date
DK1165584T3 true DK1165584T3 (da) 2004-05-17

Family

ID=10849939

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00909534T DK1165584T3 (da) 1999-03-19 2000-03-15 2'-substitueret RNA fremstilling

Country Status (12)

Country Link
US (1) US6884881B1 (da)
EP (1) EP1165584B1 (da)
JP (1) JP2002540117A (da)
KR (1) KR20020013511A (da)
AT (1) ATE258187T1 (da)
AU (1) AU3181600A (da)
CA (1) CA2362714A1 (da)
DE (1) DE60007848T2 (da)
DK (1) DK1165584T3 (da)
ES (1) ES2215032T3 (da)
GB (1) GB9906328D0 (da)
WO (1) WO2000056747A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2254306T3 (es) * 2000-10-25 2006-06-16 F. Hoffmann-La Roche Ag Amplificacion usando cebadores modificados.
KR100480498B1 (ko) * 2002-05-24 2005-04-06 학교법인 포항공과대학교 뉴클레오시드를 이용한 저분자 유기 젤레이터 및 그합성방법
CN102993255B (zh) * 2011-09-19 2016-02-10 上海兆维科技发展有限公司 2’-o-(2-甲氧乙基)-5-甲基尿苷和2’-o-(2-甲氧乙基)-5-甲基胞苷及其衍生物的制备及其纯化方法
CN114369124B (zh) * 2022-01-21 2024-03-26 北京瑞博奥医药科技有限公司 一种2`-位取代嘧啶类核苷的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2192950A1 (en) 1994-06-22 1995-12-28 Danny P.C. Mcgee Novel method of preparation of known and novel 2'-modified nucleosides by intramolecular nucleophilic displacement
JPH10512894A (ja) * 1995-03-06 1998-12-08 アイシス・ファーマシューティカルス・インコーポレーテッド ２’−ｏ−置換ピリミジンおよびそのオリゴマー化合物の合成の改良法

Also Published As

Publication number Publication date
GB9906328D0 (en) 1999-05-12
ATE258187T1 (de) 2004-02-15
JP2002540117A (ja) 2002-11-26
DE60007848D1 (de) 2004-02-26
AU3181600A (en) 2000-10-09
KR20020013511A (ko) 2002-02-20
ES2215032T3 (es) 2004-10-01
WO2000056747A1 (en) 2000-09-28
CA2362714A1 (en) 2000-09-28
DE60007848T2 (de) 2004-12-30
EP1165584B1 (en) 2004-01-21
EP1165584A1 (en) 2002-01-02
US6884881B1 (en) 2005-04-26

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