HK1046142A1 - Process for preparing n-(4hydroxyphenyl)-N' -4'-aminophenyl)- piperazine. - Google Patents

Process for preparing n-(4hydroxyphenyl)-N' -4'-aminophenyl)- piperazine.

Info

Publication number
HK1046142A1
HK1046142A1 HK02107791A HK02107791A HK1046142A1 HK 1046142 A1 HK1046142 A1 HK 1046142A1 HK 02107791 A HK02107791 A HK 02107791A HK 02107791 A HK02107791 A HK 02107791A HK 1046142 A1 HK1046142 A1 HK 1046142A1
Authority
HK
Hong Kong
Prior art keywords
compound
formula
aminophenyl
piperazine
preparing
Prior art date
Application number
HK02107791A
Other languages
English (en)
Inventor
Brigitte Giesinger
Ingrid Mergelsberg
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of HK1046142A1 publication Critical patent/HK1046142A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
HK02107791A 1999-11-08 2002-10-28 Process for preparing n-(4hydroxyphenyl)-N' -4'-aminophenyl)- piperazine. HK1046142A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43504999A 1999-11-08 1999-11-08
PCT/US2000/030457 WO2001034587A2 (en) 1999-11-08 2000-11-06 Process for preparing n-(4-hydroxy-phenyl)-n'-(4'-aminophenyl)-piperazine

Publications (1)

Publication Number Publication Date
HK1046142A1 true HK1046142A1 (en) 2002-12-27

Family

ID=23726755

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02107791A HK1046142A1 (en) 1999-11-08 2002-10-28 Process for preparing n-(4hydroxyphenyl)-N' -4'-aminophenyl)- piperazine.

Country Status (11)

Country Link
EP (1) EP1230231B1 (xx)
JP (1) JP4903963B2 (xx)
CN (1) CN1177840C (xx)
AT (1) ATE298325T1 (xx)
AU (1) AU1465301A (xx)
CA (1) CA2390296C (xx)
DE (1) DE60020988T2 (xx)
ES (1) ES2240202T3 (xx)
HK (1) HK1046142A1 (xx)
MX (1) MXPA02004545A (xx)
WO (1) WO2001034587A2 (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007075869A2 (en) 2005-12-23 2007-07-05 Ariad Pharmaceuticals, Inc. Bicyclic heteroaryl compounds
RU2585760C2 (ru) 2010-05-19 2016-06-10 Сандоз Аг Способ получения хиральных триазолонов
MX2012013331A (es) 2010-05-19 2013-02-01 Sandoz Ag Purificacion de posaconazol y de intermediarios de posaconazol.
MX337804B (es) 2010-05-19 2016-03-18 Sandoz Ag Proceso para la preparacion de hidrazinas quirales.
BR112012029226A2 (pt) 2010-05-19 2015-10-20 Sandoz Ag processo para a preparação de um composto quiral, composto quiral cristalino, sal de hcl do composto quiral cristalino, composto quiral e uso do composto
CN101824009A (zh) * 2010-05-27 2010-09-08 北京德众万全药物技术开发有限公司 一种泊沙康唑及其哌嗪中间体的简单制备方法
CN103635465A (zh) 2011-06-16 2014-03-12 桑多斯股份公司 制备手性化合物的方法
CA3022250A1 (en) 2012-12-12 2014-06-12 Ariad Pharmaceuticals, Inc. Crystalline forms of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide mono hydrochloride
EP2789610A1 (en) 2013-04-10 2014-10-15 Sandoz Ag Purification of Posaconazole Intermediates
CN108003118A (zh) * 2017-12-27 2018-05-08 张家口市格瑞高新技术有限公司 一种泊沙康唑中间体1-（4-羟基苯基）-4-（4-氨基苯基）-哌嗪的制备工艺
CN114516849A (zh) * 2020-11-18 2022-05-20 江苏恒盛药业有限公司 一种1-(4-氨基苯基)-4-(4-羟基苯基)哌嗪的合成方法
CN114276315A (zh) * 2021-12-16 2022-04-05 苏州汉德创宏生化科技有限公司 一种4-[4-[4-(4-羟基苯基)哌嗪-1-基]苯基]氨基甲酸苯酯的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0753715B2 (ja) * 1986-02-25 1995-06-07 大塚製薬株式会社 ベンゾヘテロ環化合物
CA1331757C (en) * 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
JPH04247074A (ja) * 1991-02-01 1992-09-03 Yoshitomi Pharmaceut Ind Ltd ４−モルホリノ安息香酸誘導体の製造法
DE4234295A1 (de) * 1992-10-12 1994-04-14 Thomae Gmbh Dr K Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
JPH0971564A (ja) * 1995-07-06 1997-03-18 Japan Tobacco Inc ベンズアミドオキシム誘導体及びその医薬用途

Also Published As

Publication number Publication date
CA2390296C (en) 2009-12-29
DE60020988T2 (de) 2006-04-27
JP2003513966A (ja) 2003-04-15
CN1387520A (zh) 2002-12-25
WO2001034587A3 (en) 2002-03-21
AU1465301A (en) 2001-06-06
ATE298325T1 (de) 2005-07-15
DE60020988D1 (de) 2005-07-28
ES2240202T3 (es) 2005-10-16
WO2001034587A2 (en) 2001-05-17
EP1230231A2 (en) 2002-08-14
JP4903963B2 (ja) 2012-03-28
CA2390296A1 (en) 2001-05-17
MXPA02004545A (es) 2002-09-02
EP1230231B1 (en) 2005-06-22
CN1177840C (zh) 2004-12-01

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20141106