HK1045856A1 - 抗细菌疫苗组合物 - Google Patents

抗细菌疫苗组合物 Download PDF

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Publication number
HK1045856A1
HK1045856A1 HK02107076.0A HK02107076A HK1045856A1 HK 1045856 A1 HK1045856 A1 HK 1045856A1 HK 02107076 A HK02107076 A HK 02107076A HK 1045856 A1 HK1045856 A1 HK 1045856A1
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HK
Hong Kong
Prior art keywords
leu
ala
lys
ser
glu
Prior art date
Application number
HK02107076.0A
Other languages
English (en)
Chinese (zh)
Inventor
D‧E‧洛沃里
D‧E‧洛沃裡
T‧E‧福勒
M‧J‧肯尼迪
Original Assignee
法玛西雅厄普约翰美国公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 法玛西雅厄普约翰美国公司 filed Critical 法玛西雅厄普约翰美国公司
Publication of HK1045856A1 publication Critical patent/HK1045856A1/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK02107076.0A 1999-04-09 2000-04-06 抗细菌疫苗组合物 HK1045856A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12868999P 1999-04-09 1999-04-09
US60/128,689 1999-04-09
US15345399P 1999-09-10 1999-09-10
US60/153,453 1999-09-10
PCT/US2000/009218 WO2000061724A2 (en) 1999-04-09 2000-04-06 Anti-bacterial vaccine compositions

Publications (1)

Publication Number Publication Date
HK1045856A1 true HK1045856A1 (zh) 2002-12-13

Family

ID=26826843

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02107076.0A HK1045856A1 (zh) 1999-04-09 2000-04-06 抗细菌疫苗组合物

Country Status (14)

Country Link
US (5) US20070237793A1 (cg-RX-API-DMAC7.html)
EP (5) EP1171577A2 (cg-RX-API-DMAC7.html)
JP (4) JP4892134B2 (cg-RX-API-DMAC7.html)
KR (4) KR20060134225A (cg-RX-API-DMAC7.html)
CN (1) CN1351653A (cg-RX-API-DMAC7.html)
AR (1) AR029622A1 (cg-RX-API-DMAC7.html)
AU (2) AU780887B2 (cg-RX-API-DMAC7.html)
BR (1) BR0009663A (cg-RX-API-DMAC7.html)
CA (1) CA2366520C (cg-RX-API-DMAC7.html)
ES (2) ES2535961T3 (cg-RX-API-DMAC7.html)
HK (1) HK1045856A1 (cg-RX-API-DMAC7.html)
MX (1) MXPA01010207A (cg-RX-API-DMAC7.html)
NZ (2) NZ514883A (cg-RX-API-DMAC7.html)
WO (1) WO2000061724A2 (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4892134B2 (ja) * 1999-04-09 2012-03-07 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 抗菌ワクチン組成物
US6790950B2 (en) * 1999-04-09 2004-09-14 Pharmacia & Upjohn Company Anti-bacterial vaccine compositions
ATE418615T1 (de) 2001-09-26 2009-01-15 Kyowa Hakko Kogyo Kk Verfahren zur herstellung von galactosehaltigem komplexem zucker
DE60236698D1 (de) * 2002-04-05 2010-07-22 Merial Sas Abgeschwächte gramnegative Bakterien
US7449178B2 (en) 2002-04-05 2008-11-11 Merial Limited Attenuated gram negative bacteria
GB0228691D0 (en) * 2002-12-09 2003-01-15 Imp College Innovations Ltd Bacterial virulence genes
EP1602720B1 (en) * 2003-03-05 2010-11-03 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Process for producing heterologous protein in e. coli
US8937154B2 (en) 2006-10-05 2015-01-20 New York Blood Center, Inc. Stabilized therapeutic small helical antiviral peptides
JP2010505831A (ja) * 2006-10-05 2010-02-25 ニューヨーク ブラッド センター， インコーポレイテッド 安定化した、治療用の小型のヘリックス性抗ウイルスペプチド
JP2011522796A (ja) 2008-05-06 2011-08-04 ニューヨーク ブラッド センター， インコーポレイテッド 抗ウイルス細胞透過性ペプチド
DE102011016772B8 (de) * 2011-04-12 2024-08-14 Mercedes-Benz Group AG Verfahren und Vorrichtung zur Überwachung zumindest eines Fahrzeuginsassen und Verfahren zum Betrieb zumindest einer Assistenzvorrichtung
WO2015066292A1 (en) 2013-11-01 2015-05-07 Merial Limited Attenuated pasteurella multocidavaccines & methods of making & use thereof
JP7183168B2 (ja) * 2017-02-10 2022-12-05 エピトピックス， エルエルシー タンパク質、及びＰａｓｔｅｕｒｅｌｌａタンパク質を含有する免疫化組成物、ならびに使用方法
TW202214294A (zh) 2020-09-30 2022-04-16 美商碩騰服務公司 具有ｈｙａＣ及ｎａｎＰ缺失之新穎多殺性巴斯德氏菌株及疫苗
TW202219269A (zh) * 2020-09-30 2022-05-16 美國農業部 新型多殺性巴斯德氏菌株及具有ｈｙａＣ與ｎａｎＰ缺失之疫苗
CN113567415A (zh) * 2021-07-05 2021-10-29 广西大学 表面增强拉曼散射结合免疫层析技术检测布鲁氏杆菌方法
CN115925536B (zh) * 2022-08-01 2025-02-28 北京农学院 靶向抑制DksA的小分子抑制剂和应用
CN116593695B (zh) * 2022-12-29 2025-08-05 重庆澳龙生物制品有限公司 一种牛多杀性巴氏杆菌荚膜a型elisa抗体检测试剂盒及其制备方法和应用

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL52815A (en) * 1977-08-24 1983-03-31 Israel State Fowl cholera vaccine and process for producing an attenuated non-virulent strain of pasteurella multocida
US4735801A (en) * 1982-09-07 1988-04-05 Board Of Trustees Of Leland Stanford Jr. University Novel non-reverting salmonella live vaccines
US5077044A (en) * 1980-05-19 1991-12-31 The Board Of Trustees Of The Leland Stanford Jr. University Novel non-reverting shigella live vaccines
SE8205892D0 (sv) 1982-10-18 1982-10-18 Bror Morein Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
DE3426532A1 (de) 1984-07-18 1986-01-30 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig Verwendung einer dna-sequenz zur expression sowie dna-struktur und expressionsvektor mit der dna-sequenz
SE8405493D0 (sv) 1984-11-01 1984-11-01 Bror Morein Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel
US4877612A (en) 1985-05-20 1989-10-31 Frank M. Berger Immunological adjuvant and process for preparing the same, pharmaceutical compositions, and process
DK166762B1 (da) 1986-01-14 1993-07-12 Nederlanden Staat Fremgangsmaade til fremstilling af immunogenkomplekser og farmaceutisk sammensaetning indeholdende saadanne komplekser
US4806352A (en) 1986-04-15 1989-02-21 Ribi Immunochem Research Inc. Immunological lipid emulsion adjuvant
CA1340522C (en) 1987-03-10 1999-05-04 Heinz Dobeli Fusion proteins containing neighbouring histidines for improved purification
IL86583A0 (en) * 1987-06-04 1988-11-15 Molecular Eng Ass Vaccine containing a derivative of a microbe and method for the production thereof
US5376369A (en) * 1987-11-03 1994-12-27 Syntex (U.S.A.) Inc. Vaccine adjuvant
DK46693D0 (cg-RX-API-DMAC7.html) * 1993-04-23 1993-04-23 Novo Nordisk As
HU219535B (hu) * 1991-03-05 2001-05-28 Wellcome Foundation Ltd. Rekombináns proteineket expresszáló, attenuált baktériumokat tartalmazó vakcinák
US5840312A (en) * 1991-05-02 1998-11-24 Institut Pasteur Recombinant Bacillus anthracis strains unable to produce the lethal factor protein or edema factor protein
AU5591694A (en) * 1992-11-06 1994-06-08 Regents Of The University Of Minnesota Composition protective against (p. multocida) pasteurellosis infection
US5585277A (en) 1993-06-21 1996-12-17 Scriptgen Pharmaceuticals, Inc. Screening method for identifying ligands for target proteins
US5587305A (en) 1993-12-06 1996-12-24 The United States Of America As Represented By The Department Of Agriculture Pasteurella haemolytica transformants
AU1662595A (en) 1994-01-28 1995-08-15 Herbert Altmann Method of determining the activity of a regulatory factor, and use of the method
JP3709564B2 (ja) 1994-08-30 2005-10-26 味の素株式会社 Ｌ−バリン及びｌ−ロイシンの製造法
RU2370541C2 (ru) * 1994-12-09 2009-10-20 Имерджент Продакт Дивелопмент Юк Лимитед Vgc2 днк salmonella typhimurium, мутантная бактерия, обладающая пониженной способностью к адаптации к условиям окружающей среды, и способ ее получения
CA2170839A1 (en) * 1995-03-01 1996-09-02 Janet Macinnes Bacterial preparations, method for producing same, and their use as vaccines
US6355450B1 (en) 1995-04-21 2002-03-12 Human Genome Sciences, Inc. Computer readable genomic sequence of Haemophilus influenzae Rd, fragments thereof, and uses thereof
GB9518220D0 (en) 1995-09-06 1995-11-08 Medical Res Council Checkpoint gene
US5994066A (en) 1995-09-11 1999-11-30 Infectio Diagnostic, Inc. Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US5925354A (en) 1995-11-30 1999-07-20 Michigan State University Riboflavin mutants as vaccines against Actinobacillus pleuropneumoniae
US5840556A (en) * 1996-05-08 1998-11-24 The United States Of America As Represented By The Department Of Agriculture Molecular genetic construction of vaccine strains of pasteurellaceae
CN1117862C (zh) * 1996-05-31 2003-08-13 阿克佐诺贝尔公司 活的减毒的产rtx巴斯德氏菌科细菌
US6020474A (en) 1997-01-15 2000-02-01 Incyte Pharmaceuticals, Inc. ATP synthase subunits
US6673538B1 (en) 1997-07-25 2004-01-06 The Trustees Of Boston University Methods and compositions for designing vaccines
US6790950B2 (en) 1999-04-09 2004-09-14 Pharmacia & Upjohn Company Anti-bacterial vaccine compositions
JP4892134B2 (ja) * 1999-04-09 2012-03-07 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 抗菌ワクチン組成物
AU7131600A (en) 1999-06-21 2001-01-09 North Carolina State University Acid-inducible promoters for gene expression
US6376211B1 (en) 1999-07-12 2002-04-23 Xoma Technology Ltd. Agents and methods for inhibiting F1/F0 ATPase

Also Published As

Publication number Publication date
JP2016019528A (ja) 2016-02-04
EP2281835A3 (en) 2011-11-23
AU2005203189B2 (en) 2007-12-20
EP1171577A2 (en) 2002-01-16
KR20060134225A (ko) 2006-12-27
EP2281834B1 (en) 2015-03-04
US8974798B2 (en) 2015-03-10
JP2010284165A (ja) 2010-12-24
JP5377433B2 (ja) 2013-12-25
EP2281833A3 (en) 2011-11-30
JP2002541790A (ja) 2002-12-10
KR20060116041A (ko) 2006-11-13
JP2013121347A (ja) 2013-06-20
AR029622A1 (es) 2003-07-10
NZ530012A (en) 2005-10-28
US20100322975A1 (en) 2010-12-23
US9289486B2 (en) 2016-03-22
CN1351653A (zh) 2002-05-29
CA2366520A1 (en) 2000-10-19
BR0009663A (pt) 2002-04-09
CA2366520C (en) 2013-10-01
US20090202594A1 (en) 2009-08-13
WO2000061724A3 (en) 2001-02-01
KR20070011622A (ko) 2007-01-24
EP2281835A2 (en) 2011-02-09
ES2439645T3 (es) 2014-01-24
AU780887B2 (en) 2005-04-21
MXPA01010207A (es) 2003-07-21
EP2281834A2 (en) 2011-02-09
AU2005203189A1 (en) 2005-08-18
ES2535961T3 (es) 2015-05-19
EP2281834A3 (en) 2011-11-23
JP5973634B2 (ja) 2016-08-23
JP4892134B2 (ja) 2012-03-07
US7763262B2 (en) 2010-07-27
EP2281835B1 (en) 2013-11-06
US20120148625A1 (en) 2012-06-14
AU4077600A (en) 2000-11-14
EP2281833A2 (en) 2011-02-09
US20150182615A1 (en) 2015-07-02
EP1860117A2 (en) 2007-11-28
US20070237793A1 (en) 2007-10-11
WO2000061724A2 (en) 2000-10-19
NZ514883A (en) 2004-03-26
EP1860117A3 (en) 2008-09-03
KR20010112937A (ko) 2001-12-22
EP2281833B1 (en) 2014-07-02

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