AU1662595A - Method of determining the activity of a regulatory factor, and use of the method - Google Patents

Method of determining the activity of a regulatory factor, and use of the method

Info

Publication number
AU1662595A
AU1662595A AU16625/95A AU1662595A AU1662595A AU 1662595 A AU1662595 A AU 1662595A AU 16625/95 A AU16625/95 A AU 16625/95A AU 1662595 A AU1662595 A AU 1662595A AU 1662595 A AU1662595 A AU 1662595A
Authority
AU
Australia
Prior art keywords
activity
determining
regulatory factor
regulatory
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU16625/95A
Inventor
Herbert Altmann
Wolfgang Wendler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medigene AG
Original Assignee
Medigene AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medigene AG filed Critical Medigene AG
Publication of AU1662595A publication Critical patent/AU1662595A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU16625/95A 1994-01-28 1995-01-27 Method of determining the activity of a regulatory factor, and use of the method Abandoned AU1662595A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4402569 1994-01-28
DE4402569 1994-01-28
PCT/EP1995/000297 WO1995020652A1 (en) 1994-01-28 1995-01-27 Method of determining the activity of a regulatory factor, and use of the method

Publications (1)

Publication Number Publication Date
AU1662595A true AU1662595A (en) 1995-08-15

Family

ID=6508926

Family Applications (1)

Application Number Title Priority Date Filing Date
AU16625/95A Abandoned AU1662595A (en) 1994-01-28 1995-01-27 Method of determining the activity of a regulatory factor, and use of the method

Country Status (3)

Country Link
AU (1) AU1662595A (en)
DE (1) DE19502584C2 (en)
WO (1) WO1995020652A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2731014B1 (en) * 1995-02-23 1997-03-28 Rhone Poulenc Rorer Sa DNA MOLECULES, PREPARATION AND USE IN GENE THERAPY
EP0850318A1 (en) * 1995-09-13 1998-07-01 Chiron Corporation Method and construct for screening for inhibitors of transcriptional activation
GB9616685D0 (en) * 1995-10-02 1996-09-25 Cancer Res Campaign Tech Antitumour vector constructs and methods
EP0790304A1 (en) * 1995-12-21 1997-08-20 AMERSHAM INTERNATIONAL plc Improvements relating to assay systems
US5948620A (en) * 1996-08-05 1999-09-07 Amersham International Plc Reverse two-hybrid system employing post-translation signal modulation
WO1998013502A2 (en) * 1996-09-27 1998-04-02 Icos Corporation Method to identify compounds for disrupting protein/protein interactions
US5885779A (en) * 1997-09-09 1999-03-23 University Of British Columbia Repressed trans-activator system for characterization of protein-protein interactions
CA2317816C (en) 1998-01-09 2009-02-17 Tvw Telethon Institute For Child Health Research Peptide detection method
AU4057600A (en) 1999-03-31 2000-10-16 Rosetta Inpharmatics, Inc. Methods for the identification of reporter and target molecules using comprehensive gene expression profiles
US6790950B2 (en) 1999-04-09 2004-09-14 Pharmacia & Upjohn Company Anti-bacterial vaccine compositions
KR20060134225A (en) 1999-04-09 2006-12-27 파마시아 앤드 업존 캄파니 엘엘씨 Anti-bacterial vaccine compositions
WO2001000815A1 (en) * 1999-05-28 2001-01-04 Sangamo Biosciences, Inc. Molecular switches
US6200746B1 (en) 1999-08-25 2001-03-13 Pharmacia & Upjohn Company Methods of identifying anti-viral agents
US6344549B1 (en) 1999-10-14 2002-02-05 Icos Corporation ATR-2 cell cycle checkpoint
CA2388599A1 (en) 1999-10-22 2001-05-03 Pharmacia & Upjohn Company Drosophila g protein coupled receptors, nucleic acids, and methods related to the same
US6734005B2 (en) 2000-05-22 2004-05-11 Pharmacia & Upjohn Company Matrix metalloproteinases
US7067626B2 (en) 2000-07-05 2006-06-27 Pharmacia & Upjohn Company Human ion channel proteins
US7179912B2 (en) 2000-09-01 2007-02-20 Icos Corporation Materials and methods to potentiate cancer treatment
DE10210285A1 (en) * 2002-03-08 2003-11-13 Medigene Ag Reversible toxin and its use
AU2003291002A1 (en) 2002-11-15 2004-06-15 Chiron Corporation Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
US8404681B2 (en) 2003-03-24 2013-03-26 Luitpold Pharmaceuticals, Inc. Xanthones, thioxanthones and acridinones as DNA-PK inhibitors
FR2861745A1 (en) * 2003-10-31 2005-05-06 Centre Nat Rech Scient Selecting compounds that inhibit the mycobacterial EthR repressor, useful in treatment of tuberculosis and leprosy, improve efficiency of conversion of ethionamide to its active form
FR2861742B1 (en) * 2003-10-31 2006-02-24 Centre Nat Rech Scient LIGANDS OF THE MYCOBATERIAN REPRESSOR ETR, SELECTION METHODS AND APPLICATIONS
ATE540115T1 (en) * 2007-07-11 2012-01-15 Yeda Res & Dev NUCLEIC ACID CONSTRUCT SYSTEMS WITH CAPABILITY TO DIAGNOSE OR TREAT A CELL CONDITION

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0370813A3 (en) * 1988-11-25 1991-06-19 Exemplar Corporation Rapid screening mutagenesis and teratogenesis assay
US5283173A (en) * 1990-01-24 1994-02-01 The Research Foundation Of State University Of New York System to detect protein-protein interactions
US5322801A (en) * 1990-04-19 1994-06-21 The General Hospital Corporation Protein partner screening assays and uses thereof
ATE142259T1 (en) * 1990-04-19 1996-09-15 Gen Hospital Corp SCREENING FOR PROTEIN PARTNERS AND THEIR USE
AU7667191A (en) * 1990-04-19 1991-11-11 General Hospital Corporation, The Screening assays for compounds which inhibit the binding of c-myc to dna
US5401629A (en) * 1990-08-07 1995-03-28 The Salk Institute Biotechnology/Industrial Associates, Inc. Assay methods and compositions useful for measuring the transduction of an intracellular signal
CZ49693A3 (en) * 1990-09-24 1994-02-16 Gen Hospital Corp Method for testing of a compound capability to inhibit onco-protein activity
CA2070058A1 (en) * 1991-05-31 1992-12-01 Robert A. Gadski Vectors and methods for assaying the regulation of apolipoprotein ai synthesis
EP0614491A1 (en) * 1991-11-18 1994-09-14 Massachusetts Institute Of Technology Transcription adaptors in eukaryotes
WO1993015227A1 (en) * 1992-01-29 1993-08-05 Duke University Method of assaying for the oncogenic state of cells
US5917122A (en) * 1992-08-26 1999-06-29 Byrne; Guerard Tetracycline repressor-mediated binary regulation system for control of gene expression in transgenic mice
WO1994029442A2 (en) * 1993-06-14 1994-12-22 Basf Aktiengesellschaft Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters

Also Published As

Publication number Publication date
DE19502584C2 (en) 1999-08-12
DE19502584A1 (en) 1995-08-03
WO1995020652A1 (en) 1995-08-03

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