FR2861742B1 - LIGANDS OF THE MYCOBATERIAN REPRESSOR ETR, SELECTION METHODS AND APPLICATIONS - Google Patents

LIGANDS OF THE MYCOBATERIAN REPRESSOR ETR, SELECTION METHODS AND APPLICATIONS

Info

Publication number
FR2861742B1
FR2861742B1 FR0312801A FR0312801A FR2861742B1 FR 2861742 B1 FR2861742 B1 FR 2861742B1 FR 0312801 A FR0312801 A FR 0312801A FR 0312801 A FR0312801 A FR 0312801A FR 2861742 B1 FR2861742 B1 FR 2861742B1
Authority
FR
France
Prior art keywords
mycobaterian
etr
repressor
ligands
applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0312801A
Other languages
French (fr)
Other versions
FR2861742A1 (en
Inventor
Frederique Frenois
Ndong Jean Engohang
Vincent Villeret
Camille Locht
Alain Baulard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Institut Pasteur de Lille, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR0312801A priority Critical patent/FR2861742B1/en
Priority to FR0404636A priority patent/FR2861745A1/en
Priority to PCT/FR2004/002721 priority patent/WO2005047538A2/en
Publication of FR2861742A1 publication Critical patent/FR2861742A1/en
Application granted granted Critical
Publication of FR2861742B1 publication Critical patent/FR2861742B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FR0312801A 2003-10-31 2003-10-31 LIGANDS OF THE MYCOBATERIAN REPRESSOR ETR, SELECTION METHODS AND APPLICATIONS Expired - Fee Related FR2861742B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR0312801A FR2861742B1 (en) 2003-10-31 2003-10-31 LIGANDS OF THE MYCOBATERIAN REPRESSOR ETR, SELECTION METHODS AND APPLICATIONS
FR0404636A FR2861745A1 (en) 2003-10-31 2004-04-30 Selecting compounds that inhibit the mycobacterial EthR repressor, useful in treatment of tuberculosis and leprosy, improve efficiency of conversion of ethionamide to its active form
PCT/FR2004/002721 WO2005047538A2 (en) 2003-10-31 2004-10-22 Ligands of the mycobacterial repressor ethr, selection methods, and applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0312801A FR2861742B1 (en) 2003-10-31 2003-10-31 LIGANDS OF THE MYCOBATERIAN REPRESSOR ETR, SELECTION METHODS AND APPLICATIONS

Publications (2)

Publication Number Publication Date
FR2861742A1 FR2861742A1 (en) 2005-05-06
FR2861742B1 true FR2861742B1 (en) 2006-02-24

Family

ID=34429800

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0312801A Expired - Fee Related FR2861742B1 (en) 2003-10-31 2003-10-31 LIGANDS OF THE MYCOBATERIAN REPRESSOR ETR, SELECTION METHODS AND APPLICATIONS

Country Status (1)

Country Link
FR (1) FR2861742B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201820863D0 (en) 2018-12-20 2019-02-06 Univ Bath Screening assay

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378603A (en) * 1987-03-30 1995-01-03 Board Of Regents, The University Of Texas System Method and composition for identifying substances which activate transcription of the LDL receptor gene
DE19502584C2 (en) * 1994-01-28 1999-08-12 Medigene Ag Ges Fuer Molekular Method for determining the activity of a regulatory factor and use of this method
FR2750705B1 (en) * 1996-07-04 1998-10-30 Centre Nat Rech Scient PROTEIN-PROTEIN INTERACTION DETECTION SYSTEM

Also Published As

Publication number Publication date
FR2861742A1 (en) 2005-05-06

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20070629