HK1042324B - 控制齊核甙酸的延展的方法 - Google Patents

控制齊核甙酸的延展的方法

Info

Publication number
HK1042324B
HK1042324B HK02102877.2A HK02102877A HK1042324B HK 1042324 B HK1042324 B HK 1042324B HK 02102877 A HK02102877 A HK 02102877A HK 1042324 B HK1042324 B HK 1042324B
Authority
HK
Hong Kong
Prior art keywords
oligonucleotide
extension
polynucleotide sequence
target polynucleotide
binding substance
Prior art date
Application number
HK02102877.2A
Other languages
English (en)
Other versions
HK1042324A1 (en
Inventor
Nurith Kurn
Yen Ping Liu
Alla Lishanski
Marc Taylor
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of HK1042324A1 publication Critical patent/HK1042324A1/xx
Publication of HK1042324B publication Critical patent/HK1042324B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
HK02102877.2A 1999-01-19 2002-04-16 控制齊核甙酸的延展的方法 HK1042324B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/233,413 US6200757B1 (en) 1999-01-19 1999-01-19 Method for controlling the extension of an oligonucleotide
PCT/US1999/029253 WO2000043544A1 (en) 1999-01-19 1999-12-10 Method for controlling the extension of an oligonucleotide

Publications (2)

Publication Number Publication Date
HK1042324A1 HK1042324A1 (en) 2002-08-09
HK1042324B true HK1042324B (zh) 2006-06-23

Family

ID=22877144

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02102877.2A HK1042324B (zh) 1999-01-19 2002-04-16 控制齊核甙酸的延展的方法

Country Status (8)

Country Link
US (1) US6200757B1 (zh)
EP (1) EP1147230B1 (zh)
JP (1) JP4657454B2 (zh)
AT (1) ATE322557T1 (zh)
CA (1) CA2358992C (zh)
DE (1) DE69930765T2 (zh)
HK (1) HK1042324B (zh)
WO (1) WO2000043544A1 (zh)

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US6274353B1 (en) 1999-09-22 2001-08-14 Genecopoeia, Inc. Method and compositions for improved polynucleotide synthesis
US7033763B2 (en) * 2000-02-23 2006-04-25 City Of Hope Pyrophosphorolysis activated polymerization (PAP)
WO2001062975A2 (en) * 2000-02-23 2001-08-30 City Of Hope Pyrophosphorolysis activated polymerization (pap): application to allele-specific amplification and nucleic acid sequence determination
EP1275735A1 (en) * 2001-07-11 2003-01-15 Roche Diagnostics GmbH Composition and method for hot start nucleic acid amplification
US6667165B2 (en) 2001-11-13 2003-12-23 Eppendorf Ag Method and compositions for reversible inhibition of thermostable polymerases
US7211382B2 (en) * 2002-04-09 2007-05-01 Orchid Cellmark Inc. Primer extension using modified nucleotides
CA2521127C (en) * 2003-04-01 2014-05-27 Eragen Biosciences, Inc. Polymerase inhibitor and method of using same
EP2489746B1 (en) 2005-06-07 2016-02-03 Luminex Corporation Methods for detection and typing of nucleic acids
US20070048758A1 (en) * 2005-06-09 2007-03-01 Epoch Biosciences, Inc. Improved primer-based amplification methods
AU2006287548A1 (en) * 2005-09-06 2007-03-15 Gen-Probe Incorporated Methods, compositions and kits for isothermal amplification of nucleic acids
ES2357746T3 (es) * 2006-03-28 2011-04-29 Commonwealth Scientific And Industrial Research Organisation Amplificación de fragmentos de adn.
DE102008005667A1 (de) 2008-01-19 2009-07-30 Olfert Landt Basenmodifizierte Primeroligomere für die Multiplex-RT-PCR
WO2010046067A1 (en) * 2008-10-20 2010-04-29 Roche Diagnostics Gmbh Improved allele-specific amplification
AU2010307991A1 (en) * 2009-10-13 2012-05-10 Syntezza Molecular Detection Israel Ltd. Methods and compositions for amplifying target sequences from nucleic acid samples
US9238832B2 (en) 2009-12-11 2016-01-19 Roche Molecular Systems, Inc. Allele-specific amplification of nucleic acids
US8614071B2 (en) 2009-12-11 2013-12-24 Roche Molecular Systems, Inc. Preferential amplification of mRNA over DNA using chemically modified primers
EP3502272A1 (en) 2010-06-21 2019-06-26 Life Technologies Corporation Compositions, kits, and methods for synthesis and/or detection of nucleic acids
US9005895B2 (en) 2010-06-21 2015-04-14 Life Technologies Corporation Compositions, methods and kits for nucleic acid synthesis and amplification
US9115394B2 (en) 2011-12-22 2015-08-25 Roche Molecular Systems, Inc. Methods and reagents for reducing non-specific amplification
CN108018343B (zh) 2012-05-10 2023-01-03 通用医疗公司 用于测定核苷酸序列的方法
CN106661612A (zh) 2014-01-27 2017-05-10 通用医疗公司 制备用于测序的核酸的方法
US9909169B2 (en) 2014-12-17 2018-03-06 Roche Molecular Systems, Inc. Allele-specific amplification of nucleic acids using blocking oligonucleotides for wild type suppression
CA3037190A1 (en) 2016-09-15 2018-03-22 ArcherDX, Inc. Methods of nucleic acid sample preparation for analysis of cell-free dna
ES2903357T3 (es) 2016-09-15 2022-04-01 Archerdx Llc Métodos de preparación de muestras de ácido nucleico
AU2019276719A1 (en) * 2018-05-31 2020-11-26 Pacific Biosciences Of California, Inc. Increased signal to noise in nucleic acid sequencing

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CA2008096A1 (en) * 1989-01-19 1990-07-19 Samuel Rose Nucleic acid amplification using single primer
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ATE188509T1 (de) 1990-02-16 2000-01-15 Hoffmann La Roche Verbesserungen in der spezifität und zweckmässigkeit der polymerase-kettenreaktion
US5348853A (en) 1991-12-16 1994-09-20 Biotronics Corporation Method for reducing non-specific priming in DNA amplification
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DK0866071T3 (da) * 1997-03-20 2005-01-17 Hoffmann La Roche Modificerede primere

Also Published As

Publication number Publication date
DE69930765T2 (de) 2006-11-23
US6200757B1 (en) 2001-03-13
HK1042324A1 (en) 2002-08-09
EP1147230A1 (en) 2001-10-24
CA2358992A1 (en) 2000-07-27
CA2358992C (en) 2010-10-12
WO2000043544A1 (en) 2000-07-27
JP4657454B2 (ja) 2011-03-23
DE69930765D1 (de) 2006-05-18
JP2002534986A (ja) 2002-10-22
EP1147230B1 (en) 2006-04-05
ATE322557T1 (de) 2006-04-15

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20151210