HK1040704B - 2-羥基丙酸類消旋物的拆分 - Google Patents

2-羥基丙酸類消旋物的拆分

Info

Publication number
HK1040704B
HK1040704B HK02102528.5A HK02102528A HK1040704B HK 1040704 B HK1040704 B HK 1040704B HK 02102528 A HK02102528 A HK 02102528A HK 1040704 B HK1040704 B HK 1040704B
Authority
HK
Hong Kong
Prior art keywords
hydroxypropionic acids
racemate splitting
racemate
hydroxypropionic
acids
Prior art date
Application number
HK02102528.5A
Other languages
English (en)
Other versions
HK1040704A1 (en
Inventor
H‧博納德
H‧理查斯
Original Assignee
Royalty Pharma Collection Trust
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Royalty Pharma Collection Trust filed Critical Royalty Pharma Collection Trust
Publication of HK1040704A1 publication Critical patent/HK1040704A1/xx
Publication of HK1040704B publication Critical patent/HK1040704B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK02102528.5A 1998-10-30 2002-04-04 2-羥基丙酸類消旋物的拆分 HK1040704B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19850301A DE19850301A1 (de) 1998-10-30 1998-10-30 Verfahren zur Racematspaltung von 2-Hydroxypropionsäuren
PCT/EP1999/007858 WO2000026170A1 (de) 1998-10-30 1999-10-16 Verfahren zur racematspaltung von 2-hydroxypropionsäuren

Publications (2)

Publication Number Publication Date
HK1040704A1 HK1040704A1 (en) 2002-06-21
HK1040704B true HK1040704B (zh) 2004-05-21

Family

ID=7886311

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02102528.5A HK1040704B (zh) 1998-10-30 2002-04-04 2-羥基丙酸類消旋物的拆分

Country Status (15)

Country Link
US (1) US6559338B1 (zh)
EP (1) EP1124782B1 (zh)
JP (1) JP3946954B2 (zh)
KR (1) KR100403905B1 (zh)
CN (1) CN1129571C (zh)
AT (1) ATE257142T1 (zh)
AU (1) AU6203599A (zh)
CA (1) CA2347758C (zh)
DE (2) DE19850301A1 (zh)
ES (1) ES2214047T3 (zh)
HK (1) HK1040704B (zh)
HU (1) HU228134B1 (zh)
IL (2) IL142669A0 (zh)
SK (1) SK284637B6 (zh)
WO (1) WO2000026170A1 (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19533023B4 (de) 1994-10-14 2007-05-16 Basf Ag Neue Carbonsäurederivate, ihre Herstellung und Verwendung
WO2010091877A2 (en) 2009-02-13 2010-08-19 Ratiopharm Gmbh Process for producing ambrisentan
DE202009009917U1 (de) 2009-07-21 2010-02-11 Ratiopharm Gmbh Ambrisentan in spezifischer kristalliner Form
JP5531097B2 (ja) * 2009-07-10 2014-06-25 カディラ・ヘルスケア・リミテッド アンブリセンタンを調製するための改善された方法およびその新規な中間体
EP2603491B1 (en) * 2010-08-12 2014-09-24 Sanofi Process for the preparation of enantiomeric forms of 2,3-diaminopropionic acid derivatives
US20140256004A1 (en) 2011-10-19 2014-09-11 Cipla Limited Process for the Preparation of an Endothelin Receptor Antagonist
CN103360241B (zh) * 2012-03-29 2016-08-03 中国药科大学 光学纯5-氧代三环[2，2，1，02，6]庚烷-3-羧酸的制备方法
CN103387525B (zh) * 2012-05-09 2015-04-01 北大方正集团有限公司 一种拆分2,3-二巯基丙醇外消旋体的方法
PL2867214T3 (pl) 2012-06-29 2017-02-28 Kern Pharma, S.L. Sposób wytwarzania pochodnych kwasów karboksylowych i ich związków pośrednich
CN103086877B (zh) * 2012-12-14 2017-08-25 浙江华海药业股份有限公司 一种2‑羟基丙酸类消旋物的拆分方法
CN104098462B (zh) * 2013-04-12 2017-11-17 江苏豪森药业集团有限公司 2‑羟基‑3‑甲氧基‑3,3‑二苯基丙酸消旋物的拆分方法
AU2014275574C1 (en) 2013-06-05 2018-09-20 Snpshot Trustee Limited Improvements in and relating to tissue sampling
CN109232220B (zh) * 2017-09-15 2021-09-10 上海健康医学院 一种3-羟基-3-苯基丙酸类化合物的化学拆分方法
CN108503535B (zh) * 2018-05-15 2021-02-26 上海予利生物科技股份有限公司 一种手性苯基乳酸的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9127304D0 (en) 1991-12-23 1992-02-19 Boots Co Plc Therapeutic agents
DE19533023B4 (de) 1994-10-14 2007-05-16 Basf Ag Neue Carbonsäurederivate, ihre Herstellung und Verwendung
US6030975A (en) * 1997-03-14 2000-02-29 Basf Aktiengesellschaft Carboxylic acid derivatives, their preparation and use in treating cancer
US6342636B1 (en) * 1997-11-06 2002-01-29 Yamakawa Chemical Industry Co., Ltd. Process for preparing optically active amines and optically active carboxylic acids, and intermediates for preparation

Also Published As

Publication number Publication date
CA2347758C (en) 2004-09-21
JP3946954B2 (ja) 2007-07-18
AU6203599A (en) 2000-05-22
CA2347758A1 (en) 2000-05-11
ES2214047T3 (es) 2004-09-01
IL142669A0 (en) 2002-03-10
WO2000026170A1 (de) 2000-05-11
US6559338B1 (en) 2003-05-06
CN1325375A (zh) 2001-12-05
HUP0104010A3 (en) 2002-12-28
DE59908211D1 (de) 2004-02-05
KR20010082276A (ko) 2001-08-29
IL142669A (en) 2006-12-10
EP1124782A1 (de) 2001-08-22
CN1129571C (zh) 2003-12-03
HUP0104010A2 (hu) 2002-03-28
JP2002528524A (ja) 2002-09-03
ATE257142T1 (de) 2004-01-15
EP1124782B1 (de) 2004-01-02
KR100403905B1 (ko) 2003-11-05
HU228134B1 (hu) 2012-12-28
SK284637B6 (sk) 2005-08-04
DE19850301A1 (de) 2000-05-04
SK5292001A3 (en) 2001-10-08
HK1040704A1 (en) 2002-06-21

Similar Documents

Publication Publication Date Title
HK1040704A1 (en) Method for racemate splitting of 2-hydroxypropionic acids
DE69527617D1 (de) Verfahren zur racematspaltung von etodolac unter verwendung von glucamin-derivaten
DE69007599T2 (de) Verfahren zur Racemisierung optisch aktiver Carbonsäureester.
AU8445691A (en) Process for transforming (benzoyl-3 phenyl)-2 propionic acid into an s(+) isomer
ATE138414T1 (de) Verfahren zur herstellung von optisch aktiver 2- arylpropionsäure
PL338894A1 (en) Method of increasing optical purity of 2r-[1-hydroxy-1-trifluoromethy-3-cyclopropylopropin-2-yl]-4-chloroaniline
ATE137736T1 (de) Verfahren zur herstellung von einem optisch reinen aminoalkohol
PT1140794E (pt) Novo processo de preparacao de aminoacidos quirais
DK0474200T3 (da) Fremgangsmåde til racematspaltning af 2,2-dimethylcyclopropancarboxylsyre
DK0442585T3 (da) Fremgangsmåde til racemisering af et optisk aktivt aminosyreamid
SE9801726D0 (sv) New process
YU12600A (sh) Postupak za povećanje optičke čistoće 2r- /1-hidroksi-1-trifluorometil-3-ciklopropilpropin-2-il/- 4-hloranilina
KR960703116A (ko) 광학활성 N-tert-부틸-2-피페라진카르복시아미드의 제조방법 및 그 라세미화법(PROCESS FOR PRODUCING OPTICALLY ACTIVE N-TERT-BUTYL-2-PIPERAZINECARBOXAMIDE AND METHOD OF RACEMIZING THE AMIDE)
RU99125069A (ru) Способ получения энантиомеров биарилкетокарбоновых кислот
HUT53854A (en) Process for the racemization of arylalkylamines

Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20191015