HK1040429B - 作為早期中樞神經系統損傷標誌的tau - Google Patents
作為早期中樞神經系統損傷標誌的tauInfo
- Publication number
- HK1040429B HK1040429B HK02100080.9A HK02100080A HK1040429B HK 1040429 B HK1040429 B HK 1040429B HK 02100080 A HK02100080 A HK 02100080A HK 1040429 B HK1040429 B HK 1040429B
- Authority
- HK
- Hong Kong
- Prior art keywords
- tau
- cns
- cns damage
- marker
- individual
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Carbon And Carbon Compounds (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Devices That Are Associated With Refrigeration Equipment (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98870190 | 1998-09-08 | ||
PCT/EP1999/006592 WO2000014546A1 (en) | 1998-09-08 | 1999-09-07 | Tau as a marker for early cns damage |
Publications (2)
Publication Number | Publication Date |
---|---|
HK1040429A1 HK1040429A1 (en) | 2002-06-07 |
HK1040429B true HK1040429B (zh) | 2005-08-12 |
Family
ID=8237090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02100080.9A HK1040429B (zh) | 1998-09-08 | 2002-01-04 | 作為早期中樞神經系統損傷標誌的tau |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1112500B1 (zh) |
JP (1) | JP4624559B2 (zh) |
CN (2) | CN1325491A (zh) |
AT (1) | ATE277353T1 (zh) |
AU (1) | AU772151B2 (zh) |
BR (1) | BR9913112A (zh) |
CA (1) | CA2340433A1 (zh) |
DE (1) | DE69920487T2 (zh) |
ES (1) | ES2229817T3 (zh) |
HK (1) | HK1040429B (zh) |
WO (1) | WO2000014546A1 (zh) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004016655A1 (ja) | 2002-08-14 | 2004-02-26 | Mitsubishi Chemical Corporation | 中枢性タウ蛋白質特異的抗体 |
WO2004032711A2 (en) | 2002-10-09 | 2004-04-22 | Dmi Biosciences, Inc. | Diagnosis and monitoring of inflammation, ischemia and appendicitis |
WO2008124066A1 (en) | 2007-04-05 | 2008-10-16 | The J. David Gladstone Institutes | Agents that reduce neuronal overexcitation |
US20110143375A1 (en) | 2008-08-11 | 2011-06-16 | Banyan Blomakers, Inc. | Biomarker detection process and assay of neurological condition |
US20130022982A1 (en) | 2009-09-14 | 2013-01-24 | Kevin Ka-Wang Wang | Micro-rna, autoantibody and protein markers for diagnosis of neuronal injury |
RU2449287C1 (ru) * | 2011-03-17 | 2012-04-27 | Государственное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГОУ ВПО СибГМУ Минздравсоцразвития) | Способ антенатального прогнозирования последствий перинатальных поражений нервной системы у детей |
WO2012142301A2 (en) | 2011-04-12 | 2012-10-18 | Quanterix Corporation | Methods of determining a treatment protocol for and/or a prognosis of a patients recovery from a brain injury |
JP6345655B2 (ja) | 2012-07-03 | 2018-06-20 | ワシントン・ユニバーシティWashington University | タウに対する抗体 |
KR101582387B1 (ko) * | 2013-12-12 | 2016-01-05 | 서울대학교산학협력단 | 뇌전이암 원인종양 진단용 조성물 및 그의 용도 |
TWI664190B (zh) | 2014-06-27 | 2019-07-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
RU2568914C1 (ru) * | 2014-07-31 | 2015-11-20 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский институт акушерства и педиатрии" Министерства здравоохранения Российской Федерации | Способ прогнозирования перинатального поражения цнс у недоношенных новорожденных |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69220503T2 (de) * | 1991-10-25 | 1998-02-05 | Innogenetics Nv | Monoklonale Antikörper gegen das mikrotubulusassoziierte Protein Tau. |
AU690092B2 (en) * | 1992-12-14 | 1998-04-23 | N.V. Innogenetics S.A. | Monoclonal antibodies directed against the microtubule-associated protein tau, hybridomas secreting these antibodies, antigen recognition by these monoclonal antibodies and their applications |
JPH06239899A (ja) * | 1993-02-12 | 1994-08-30 | Teijin Ltd | ヒトタウ蛋白に対する抗体、並びに該抗体を利用する体液中のヒトタウ蛋白の測定方法 |
EP0772634B1 (en) * | 1994-07-29 | 2003-03-12 | Innogenetics N.V. | Monoclonal antibodies specific for an epitope of a particular subclass or form of phosphorylated tau, hybridomas secreting them, antigen recognition of these antibodies and their applications |
US7427392B1 (en) * | 1994-11-14 | 2008-09-23 | Elan Pharmaceuticals, Inc. | Methods for aiding in the diagnosis of alzheimer's disease by measuring amyloid-β peptide (x-≧41) and tau |
-
1999
- 1999-09-07 EP EP99968716A patent/EP1112500B1/en not_active Expired - Lifetime
- 1999-09-07 DE DE69920487T patent/DE69920487T2/de not_active Expired - Lifetime
- 1999-09-07 ES ES99968716T patent/ES2229817T3/es not_active Expired - Lifetime
- 1999-09-07 BR BR9913112-9A patent/BR9913112A/pt not_active IP Right Cessation
- 1999-09-07 AU AU59746/99A patent/AU772151B2/en not_active Expired
- 1999-09-07 CA CA002340433A patent/CA2340433A1/en not_active Abandoned
- 1999-09-07 JP JP2000569239A patent/JP4624559B2/ja not_active Expired - Fee Related
- 1999-09-07 AT AT99968716T patent/ATE277353T1/de not_active IP Right Cessation
- 1999-09-07 CN CN99812850A patent/CN1325491A/zh active Pending
- 1999-09-07 WO PCT/EP1999/006592 patent/WO2000014546A1/en active IP Right Grant
- 1999-09-07 CN CN2007101032457A patent/CN101046476B/zh not_active Expired - Fee Related
-
2002
- 2002-01-04 HK HK02100080.9A patent/HK1040429B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HK1040429A1 (en) | 2002-06-07 |
CN1325491A (zh) | 2001-12-05 |
CN101046476B (zh) | 2013-04-10 |
WO2000014546A1 (en) | 2000-03-16 |
BR9913112A (pt) | 2001-05-08 |
EP1112500B1 (en) | 2004-09-22 |
CA2340433A1 (en) | 2000-03-16 |
JP2002524740A (ja) | 2002-08-06 |
AU5974699A (en) | 2000-03-27 |
DE69920487D1 (de) | 2004-10-28 |
ES2229817T3 (es) | 2005-04-16 |
ATE277353T1 (de) | 2004-10-15 |
CN101046476A (zh) | 2007-10-03 |
AU772151B2 (en) | 2004-04-08 |
EP1112500A1 (en) | 2001-07-04 |
DE69920487T2 (de) | 2006-03-09 |
JP4624559B2 (ja) | 2011-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CHRG | Changes in the register |
Free format text: ADDITION OF INVENTOR: ANDRE VAN DE VOORDE; STEFAAN VAN GOOL |
|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20160907 |