HK1037628A1 - Condensed thienopyrimidines with phosphodiesterase-v inhibiting action and the method for preparing the same and use thereof. - Google Patents

Condensed thienopyrimidines with phosphodiesterase-v inhibiting action and the method for preparing the same and use thereof.

Info

Publication number
HK1037628A1
HK1037628A1 HK01108477A HK01108477A HK1037628A1 HK 1037628 A1 HK1037628 A1 HK 1037628A1 HK 01108477 A HK01108477 A HK 01108477A HK 01108477 A HK01108477 A HK 01108477A HK 1037628 A1 HK1037628 A1 HK 1037628A1
Authority
HK
Hong Kong
Prior art keywords
thienopyrimidines
phosphodiesterase
condensed
preparing
same
Prior art date
Application number
HK01108477A
Other languages
English (en)
Inventor
Rochus Jonas
Pierre Schelling
Fran-Werner Kluxen
Maria Christadler
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HK1037628A1 publication Critical patent/HK1037628A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK01108477A 1998-04-29 2001-12-03 Condensed thienopyrimidines with phosphodiesterase-v inhibiting action and the method for preparing the same and use thereof. HK1037628A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19819023A DE19819023A1 (de) 1998-04-29 1998-04-29 Thienopyrimidine
PCT/EP1999/002738 WO1999055708A1 (de) 1998-04-29 1999-04-23 Kondensierte thienopyrimidine mit pde v inhibierender wirkung

Publications (1)

Publication Number Publication Date
HK1037628A1 true HK1037628A1 (en) 2002-02-15

Family

ID=7866082

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01108477A HK1037628A1 (en) 1998-04-29 2001-12-03 Condensed thienopyrimidines with phosphodiesterase-v inhibiting action and the method for preparing the same and use thereof.

Country Status (27)

Country Link
US (1) US6495557B1 (sk)
EP (1) EP1084125B1 (sk)
JP (1) JP4242561B2 (sk)
KR (1) KR20010042628A (sk)
CN (1) CN1142936C (sk)
AR (1) AR016233A1 (sk)
AT (1) ATE314374T1 (sk)
AU (1) AU743230B2 (sk)
BR (1) BR9910032A (sk)
CA (1) CA2328280C (sk)
CO (1) CO5011050A1 (sk)
CZ (1) CZ291109B6 (sk)
DE (2) DE19819023A1 (sk)
ES (1) ES2255754T3 (sk)
HK (1) HK1037628A1 (sk)
HU (1) HUP0101832A3 (sk)
ID (1) ID27049A (sk)
MY (1) MY121864A (sk)
NO (1) NO20005434L (sk)
PL (1) PL343637A1 (sk)
RU (1) RU2224760C2 (sk)
SK (1) SK15972000A3 (sk)
TR (1) TR200003144T2 (sk)
TW (1) TWI232220B (sk)
UA (1) UA66856C2 (sk)
WO (1) WO1999055708A1 (sk)
ZA (1) ZA200006994B (sk)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19928146A1 (de) * 1999-06-19 2000-12-21 Merck Patent Gmbh Thienopyrimidine
DE19943815A1 (de) * 1999-09-14 2001-03-15 Merck Patent Gmbh Verwendung von Thienopyrimidinen
DE19944604A1 (de) * 1999-09-17 2001-03-22 Merck Patent Gmbh Aminderivate
DE10001021A1 (de) * 2000-01-13 2001-07-19 Merck Patent Gmbh Pharmazeutische Zubereitung
US20030153585A1 (en) * 2000-01-13 2003-08-14 Sven-Alexander Schreder Pharmaceutical preparations containing 2-pyrrolidone as the dissolving intermediary
DE10010612A1 (de) * 2000-03-03 2001-09-27 Merck Patent Gmbh Verwendung von PDE V-Inhibitoren
DE10017947A1 (de) 2000-04-11 2001-10-25 Merck Patent Gmbh Verfahren zur Herstellung benzo-annelierter Heterocyclen
DE10031585A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 2-Aminoalkyl-thieno[2,3-d]pyrimidine
MXPA03005441A (es) * 2000-12-19 2003-09-10 Merck Patent Gmbh Formulacion farmaceutica que contiene tienopirimidinas y antitromboticos, antagonistas de calcio, prostaglandinas o derivados de prostaglandina (2).
DE10064994A1 (de) * 2000-12-23 2002-07-04 Merck Patent Gmbh Sulfamidothienopyrimidine
CZ20032339A3 (cs) * 2001-01-31 2004-09-15 Merck Patent Gmbh Farmaceutický prostředek obsahující parazolo [4,3-d]pyrimidiny a nitráty nebo thienopyrimidiny a nitráty
DE10107261B4 (de) * 2001-02-16 2005-03-10 Merck Patent Gmbh Pharmazeutische Zusammensetzung
DE10148883A1 (de) * 2001-10-04 2003-04-10 Merck Patent Gmbh Pyrimidinderivate
JPWO2003035653A1 (ja) * 2001-10-26 2005-02-10 日本曹達株式会社 ピリドチエノピリミジン化合物およびその塩
US8207172B2 (en) * 2004-08-20 2012-06-26 Bayer Intellectual Property Gmbh Pyrimidinothienoindazoles useful for the treatment of hyperproliferative disorders
ES2259891B1 (es) * 2004-11-30 2007-11-01 Laboratorios Almirall S.A. Nuevos derivados de piridotienopirimidina.
ES2259892B1 (es) * 2004-11-30 2007-11-01 Laboratorios Almirall S.A. Nuevos derivados de piridotienopirimidina.
MX2007012711A (es) 2005-04-19 2008-01-11 Nycomed Gmbh Roflumilast para el tratamiento de hipertension pulmonar.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2657760B2 (ja) 1992-07-15 1997-09-24 小野薬品工業株式会社 ４−アミノキナゾリン誘導体およびそれを含有する医薬品
PH31122A (en) * 1993-03-31 1998-02-23 Eisai Co Ltd Nitrogen-containing fused-heterocycle compounds.
GB9301192D0 (en) * 1993-06-09 1993-06-09 Trott Francis W Flower shaped mechanised table
ATE163647T1 (de) 1993-08-26 1998-03-15 Ono Pharmaceutical Co 4-aminopyrimidin derivate
US5869486A (en) 1995-02-24 1999-02-09 Ono Pharmaceutical Co., Ltd. Fused pyrimidines and pyriazines as pharmaceutical compounds
DE19632423A1 (de) 1996-08-12 1998-02-19 Merck Patent Gmbh Thienopyrimidine
DE19644228A1 (de) 1996-10-24 1998-04-30 Merck Patent Gmbh Thienopyrimidine
DE19752952A1 (de) 1997-11-28 1999-06-02 Merck Patent Gmbh Thienopyrimidine

Also Published As

Publication number Publication date
HUP0101832A3 (en) 2002-11-28
NO20005434D0 (no) 2000-10-27
CN1298406A (zh) 2001-06-06
ATE314374T1 (de) 2006-01-15
CA2328280C (en) 2009-09-29
UA66856C2 (uk) 2004-06-15
CO5011050A1 (es) 2001-02-28
BR9910032A (pt) 2001-10-16
WO1999055708A1 (de) 1999-11-04
AU3709899A (en) 1999-11-16
SK15972000A3 (sk) 2001-05-10
AU743230B2 (en) 2002-01-24
HUP0101832A2 (hu) 2001-11-28
EP1084125A1 (de) 2001-03-21
MY121864A (en) 2006-02-28
DE59912986D1 (de) 2006-02-02
ID27049A (id) 2001-02-22
CN1142936C (zh) 2004-03-24
EP1084125B1 (de) 2005-12-28
ZA200006994B (en) 2002-05-28
TR200003144T2 (tr) 2001-03-21
CA2328280A1 (en) 1999-11-04
US6495557B1 (en) 2002-12-17
RU2224760C2 (ru) 2004-02-27
TWI232220B (en) 2005-05-11
ES2255754T3 (es) 2006-07-01
CZ291109B6 (cs) 2002-12-11
PL343637A1 (en) 2001-08-27
JP4242561B2 (ja) 2009-03-25
CZ20003976A3 (cs) 2001-02-14
NO20005434L (no) 2000-10-27
DE19819023A1 (de) 1999-11-04
KR20010042628A (ko) 2001-05-25
JP2002513026A (ja) 2002-05-08
AR016233A1 (es) 2001-06-20

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080423