HK1034978A1 - Adenosine derivatives. - Google Patents

Adenosine derivatives.

Info

Publication number
HK1034978A1
HK1034978A1 HK01105686A HK01105686A HK1034978A1 HK 1034978 A1 HK1034978 A1 HK 1034978A1 HK 01105686 A HK01105686 A HK 01105686A HK 01105686 A HK01105686 A HK 01105686A HK 1034978 A1 HK1034978 A1 HK 1034978A1
Authority
HK
Hong Kong
Prior art keywords
adenosine derivatives
adenosine
derivatives
Prior art date
Application number
HK01105686A
Other languages
English (en)
Inventor
David Edmund Bays
Richard Peter Charles Cousins
Hazel Joan Dyke
Colin David Eldred
Brian David Judkins
Martin Pass
Andrew Michael Kenneth Pennell
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of HK1034978A1 publication Critical patent/HK1034978A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HK01105686A 1998-06-23 2001-08-14 Adenosine derivatives. HK1034978A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9813554.4A GB9813554D0 (en) 1998-06-23 1998-06-23 Chemical compounds
PCT/EP1999/004182 WO1999067262A1 (en) 1998-06-23 1999-06-21 Adenosine derivatives

Publications (1)

Publication Number Publication Date
HK1034978A1 true HK1034978A1 (en) 2001-11-09

Family

ID=10834247

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01105686A HK1034978A1 (en) 1998-06-23 2001-08-14 Adenosine derivatives.

Country Status (40)

Country Link
US (2) US6492348B1 (es)
EP (2) EP1090019B1 (es)
JP (2) JP3378240B2 (es)
KR (1) KR100612797B1 (es)
CN (2) CN1616459A (es)
AP (1) AP2000002014A0 (es)
AR (1) AR018917A1 (es)
AT (1) ATE277941T1 (es)
AU (1) AU758018B2 (es)
BG (1) BG65064B1 (es)
BR (1) BR9911498A (es)
CA (1) CA2335520C (es)
CO (1) CO5040216A1 (es)
DE (1) DE69920697T2 (es)
EA (1) EA003828B1 (es)
EE (1) EE04853B1 (es)
ES (1) ES2226399T3 (es)
GB (1) GB9813554D0 (es)
GE (1) GEP20032958B (es)
HK (1) HK1034978A1 (es)
HR (1) HRP20000896B1 (es)
HU (1) HUP0102453A3 (es)
ID (1) ID27484A (es)
IL (2) IL140284A0 (es)
IS (1) IS5773A (es)
MY (1) MY122481A (es)
NO (1) NO318788B1 (es)
NZ (1) NZ508915A (es)
OA (1) OA11574A (es)
PE (1) PE20000704A1 (es)
PL (1) PL194087B1 (es)
PT (1) PT1090019E (es)
RS (1) RS50042B (es)
SI (1) SI1090019T1 (es)
SK (1) SK19582000A3 (es)
TR (1) TR200100449T2 (es)
TW (1) TW541312B (es)
UA (1) UA64794C2 (es)
WO (1) WO1999067262A1 (es)
ZA (1) ZA200007514B (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9813554D0 (en) * 1998-06-23 1998-08-19 Glaxo Group Ltd Chemical compounds
JP5042425B2 (ja) * 2000-03-01 2012-10-03 ユーロセルティック ソシエテ アノニム 機能性胃腸疾患治療用トラマドール
US20040162422A1 (en) * 2001-03-20 2004-08-19 Adrian Hall Chemical compounds
GB0106867D0 (en) 2001-03-20 2001-05-09 Glaxo Group Ltd Process
GB0115178D0 (en) * 2001-06-20 2001-08-15 Glaxo Group Ltd Compounds
GB0115182D0 (en) * 2001-06-20 2001-08-15 Glaxo Group Ltd Medicaments
US6946449B2 (en) 2001-07-13 2005-09-20 Cv Therapeutics, Inc. Partial and full agonists of A1 adenosine receptors
US7713946B2 (en) 2002-07-11 2010-05-11 Cv Therapeutics, Inc. Partial and full agonists A1 adenosine receptors
US7157440B2 (en) 2001-07-13 2007-01-02 Cv Therapeutics, Inc. Partial and full agonists of A1 adenosine receptors
JP2005527502A (ja) 2002-02-19 2005-09-15 シーブイ・セラピューティクス・インコーポレイテッド Ａ１アデノシン受容体の部分的および全アゴニスト
EP1513858A2 (en) * 2002-06-17 2005-03-16 Glaxo Group Limited Process for the preparation of heterocyclyl substituted adenosine derivatives
ATE368048T1 (de) * 2002-08-15 2007-08-15 Cv Therapeutics Inc Partielle und volle agonisten von a1- adenosinrezeptoren
AU2003298204A1 (en) * 2002-12-18 2004-07-09 Glaxo Group Limited Adenosine derivative in polymorph v form
AU2003290088A1 (en) * 2002-12-18 2004-07-09 Glaxo Group Limited Adenosine derivative in polymorph iv form
AU2003292255A1 (en) * 2002-12-18 2004-07-09 Glaxo Group Limited Polymorph
AU2004209986C1 (en) 2003-02-03 2009-08-13 Gilead Palo Alto, Inc. Partial and full agonists of A1 adenosine receptors
WO2005053712A1 (en) * 2003-12-02 2005-06-16 Glaxo Group Limited Use of adenonsine derivatives for treating dyslipidemia, obesity, cardiovascular risk factors, metabolic syndrome, polycystic ovary syndrome, niddm
GT200500281A (es) * 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
GB0500785D0 (en) * 2005-01-14 2005-02-23 Novartis Ag Organic compounds
GB0607944D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
AR060607A1 (es) 2006-04-21 2008-07-02 Novartis Ag Derivados de purina,composiciones farmaceuticas que los contienen, metodo de preparacion y usos en enfermedades obstructivas o inflamatorias de las vias respiratorias.
GB0607950D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607953D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607954D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607948D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
EP1889846A1 (en) 2006-07-13 2008-02-20 Novartis AG Purine derivatives as A2a agonists
EP1903044A1 (en) * 2006-09-14 2008-03-26 Novartis AG Adenosine Derivatives as A2A Receptor Agonists
MX2009004991A (es) * 2006-11-10 2009-05-20 Novartis Ag Derivados de monoacetato de ciclopenteno-diol.
US20090088403A1 (en) * 2007-05-07 2009-04-02 Randy Blakely A3 adenosine receptors as targets for the modulation of central serotonergic signaling
CN101712709A (zh) * 2008-10-06 2010-05-26 中国医学科学院药物研究所 三乙酰基-3-羟基苯基腺苷及其调血脂的用途
EP2849566B1 (en) * 2012-02-11 2018-04-04 Academia Sinica Adenosine analogues for the treatment of pain
MX2017010844A (es) * 2015-02-24 2017-12-07 Pfizer Derivados de nucleosidos sustituidos utiles como agentes anticancerosos.
CN108864099A (zh) * 2018-09-08 2018-11-23 湖北荆洪生物科技股份有限公司 一种高纯6-糠氨基嘌呤的合成方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962194A (en) * 1987-04-02 1990-10-09 Warner-Lambert Company Method of preparing 51,N6-disubstituted adenosines from inosines
US5646128A (en) * 1989-09-15 1997-07-08 Gensia, Inc. Methods for treating adenosine kinase related conditions
US5244896A (en) * 1990-09-14 1993-09-14 Marion Merrell Dow Inc. Carbocyclic adenosine analogs useful as immunosuppressants
DK62592D0 (es) * 1992-05-14 1992-05-14 Novo Nordisk As
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
ES2132419T3 (es) * 1993-07-23 1999-08-16 Merrell Pharma Inc Nuevos agentes de nucleosidos 9-n-biciclicos utiles como inhibidores selectivos de citocinas proinflamatorias.
WO1998001459A1 (en) * 1996-07-05 1998-01-15 Novo Nordisk A/S Novel n-alkoxyadenine derivatives acting as cytokine inhibitors
UA51716C2 (uk) * 1996-07-08 2002-12-16 Авентіс Фармасьютікалз Продактс Інк. Сполуки, що мають гіпотензивну, кардіопротекторну, анти-ішемічну та антиліполітичну властивості, фармацевтична композиція та способи лікування
AU4377397A (en) * 1996-10-14 1998-05-11 Novo Nordisk A/S Novel therapeutically active adenosine derivatives
TW528755B (en) * 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
PE20000270A1 (es) 1998-02-14 2000-05-20 Glaxo Group Ltd Derivados de 2-(purin-9-il)-tetrahidrofuran-3,4-diol
GB9813554D0 (en) * 1998-06-23 1998-08-19 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
KR100612797B1 (ko) 2006-08-17
HRP20000896A2 (en) 2001-12-31
CA2335520A1 (en) 1999-12-29
HUP0102453A3 (en) 2002-10-28
GEP20032958B (en) 2003-04-25
BR9911498A (pt) 2001-03-20
OA11574A (en) 2004-07-21
CN1202118C (zh) 2005-05-18
CO5040216A1 (es) 2001-05-29
NO20006520L (no) 2001-02-14
NO20006520D0 (no) 2000-12-20
UA64794C2 (en) 2004-03-15
JP3378240B2 (ja) 2003-02-17
NO318788B1 (no) 2005-05-09
US6492348B1 (en) 2002-12-10
DE69920697T2 (de) 2005-02-24
IL140284A0 (en) 2002-02-10
ES2226399T3 (es) 2005-03-16
RS50042B (sr) 2008-11-28
TR200100449T2 (tr) 2001-08-21
YU82800A (sh) 2003-04-30
BG65064B1 (bg) 2007-01-31
NZ508915A (en) 2003-09-26
US20030096788A1 (en) 2003-05-22
AU758018B2 (en) 2003-03-13
HUP0102453A2 (hu) 2002-04-29
EP1090019A1 (en) 2001-04-11
EP1090019B1 (en) 2004-09-29
DE69920697D1 (de) 2004-11-04
IL140284A (en) 2006-04-10
ATE277941T1 (de) 2004-10-15
JP2002518509A (ja) 2002-06-25
TW541312B (en) 2003-07-11
ZA200007514B (en) 2002-01-23
US6677316B2 (en) 2004-01-13
AR018917A1 (es) 2001-12-12
PE20000704A1 (es) 2000-08-03
GB9813554D0 (en) 1998-08-19
PL194087B1 (pl) 2007-04-30
HRP20000896B1 (en) 2006-03-31
AP2000002014A0 (en) 2000-12-31
JP2003040891A (ja) 2003-02-13
KR20010083067A (ko) 2001-08-31
ID27484A (id) 2001-04-12
EP1447407A1 (en) 2004-08-18
WO1999067262A1 (en) 1999-12-29
CN1314910A (zh) 2001-09-26
EA003828B1 (ru) 2003-10-30
SK19582000A3 (sk) 2001-11-06
CA2335520C (en) 2007-02-20
IS5773A (is) 2000-12-15
SI1090019T1 (en) 2005-02-28
MY122481A (en) 2006-04-29
AU4514699A (en) 2000-01-10
PT1090019E (pt) 2005-01-31
EE200000784A (et) 2002-04-15
PL345089A1 (en) 2001-12-03
EA200001222A1 (ru) 2001-08-27
BG105155A (en) 2001-09-28
CN1616459A (zh) 2005-05-18
EE04853B1 (et) 2007-06-15

Similar Documents

Publication Publication Date Title
HK1034978A1 (en) Adenosine derivatives.
ZA99254B (en) Benzosulfone derivatives.
HK1047942A1 (en) Purine derivatives.
ZA200110208B (en) Purine derivatives.
HK1047110A1 (en) Purine derivatives.
PL346155A1 (en) 1h-imidazopyridine derivatives
PL345540A1 (en) Thiobenzimidazole derivatives
ZA200005136B (en) Dihydropyrimides.
ZA9811940B (en) Novel erythromycin derivatives.
GB9809664D0 (en) a-Ketoamide derivatives
ZA992322B (en) Phosphodiesterase iv-inhibiting diazepinoindoles.
ZA991550B (en) Cyclohexanediole derivatives.
ZA992443B (en) Hydroxy-methyl-hexanones.
EG23802A (en) 2-Phenylpyran-4-one derivatives
ZA982436B (en) Thiazolimine derivatives.
ZA993123B (en) Trisresorcinyltriazines.
ZA995325B (en) Methylcyclotetradec-5-en-1-ones.
ZA983902B (en) Erythromycin derivatives.
GB9827729D0 (en) Thieno-indole derivatives
ZA994369B (en) Acridin derivatives.
EP1061912A4 (en) PHENANTHROFURANDERIVATE
IL139276A0 (en) Cyclohexenondioxthio chromanoyl derivatives
ZA981307B (en) 4-aminoethoxyindazole derivatives.
HK1042478A1 (zh) 2-氧代-2h-喹啉衍生物
ZA200007320B (en) Hydrazine derivatives.

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090621